Hector Peinado
@hps2022.bsky.social
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Group Leader of the Microenviroment and Metastasis Laboratory at CNB, Madrid, Spain.
Proud of our impact in the field!, Special thanks to David and all colleagues 👏👏👏.
www.frontiersin.org/journals/imm...
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Frontiers | Global hotspots and trends in pre-metastatic niche research: a bibliometric analysis(2005-2024)
BackgroundThe pre-metastatic niche (PMN) represents the microenvironment established in target organs before primary tumor metastasis, playing a crucial role...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1552053/full
4 months ago
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Hector Peinado
Fernando Calvo
6 months ago
New preprint alert 🚨 We are pleased to share our most recent story about how
#CAFs
rely on stress responses and proteostasis control to maintain their aberrantly activated state. A work spearheaded by Silvia Dominguez in my lab🧪.
doi.org/10.1101/2025...
🧵1/11
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Proteostasis control via HSP90α sustains YAP activity to drive aggressive behaviours in cancer-associated fibroblasts
Cancers adapt proteostasis to cope with the burden of misfolded proteins, stabilize key signalling nodes and sustain their malignant behaviour. Tumour stroma is subjected to similar stresses, but how ...
https://doi.org/10.1101/2025.04.04.647210
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Hector Peinado
6 months ago
Un estudio liderado por Héctor Peinado
@hps2022.bsky.social
, del #CNIOStopCancer, descubre que una dieta alta en grasas favorece la metástasis del cáncer de mama en modelos animales. Se publica en
@naturecomms.bsky.social
#CNIOStopCancer,
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La dieta alta en grasas favorece la metástasis del cáncer de mama en modelos animales
La obesidad se asocia a un mayor riesgo de desarrollar cáncer de mama, y a más propensión a que el cáncer se disemine a otros órganos –haga metástasis–. Pero las causas de esta asociación todavía no se entienden bien. Investigadores del Centro Nacional de Investigaciones Oncológicas (CNIO) aportan ahora nuevos datos, al descubrir que una […]
https://bit.ly/4hMAo4J
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Hector Peinado
6 months ago
A study led by Peinado
@hps2022.bsky.social
, at #CNIOStopCancer, discovers that a high-fat diet promote breast cancer metastasis in animal models. It appears in
@naturecomms.bsky.social
#CNIOStopCancer,
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High-fat diet promotes breast cancer metastasis in animal models
Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are still not well understood. Researchers at the Spanish National Cancer Research Center (CNIO) have now provided new data by discovering that a […]
https://www.cnio.es/en/news/high-fat-diet-promotes-breast-cancer-metastasis-in-animal-models/
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Happy to share our latest work
@cniostopcancer.bsky.social
@naturecomms.bsky.social
, defining the impact of a high fat diet on pre-metastatic niche formation - Thaks to my team members involved, collaborators and funding sources, specially
@worldwidecancer.bsky.social
.
www.nature.com/articles/s41...
6 months ago
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👉Vamos que nos vamos!! 🚨🚨Tienes hasta ESTE VIERNES 28 (🪐alineamiento de planetas🪐) para apuntarte un CURSO ON LINE sobre todo lo que siempre quisiste saber y nunca te atreviste a preguntar sobre VESICULAS EXTRACELULARES
postgrado.ufv.es/curso-de-esp...
8 months ago
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Hector Peinado
Ivano Amelio
8 months ago
Incredibly timely and informative review article
@cp-cell.bsky.social
by
@jstingele.bsky.social
and team on
#RNA
Damage
www.cell.com/cell/fulltex...
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Cellular responses to RNA damage
RNA plays a central role in protein biosynthesis and performs diverse regulatory and catalytic functions, making it essential for all processes of life. Like DNA, RNA is constantly subjected to damage...
https://www.cell.com/cell/fulltext/S0092-8674(25)00034-0?dgcid=raven_jbs_etoc_email
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Hector Peinado
Science Magazine
8 months ago
Researchers have constructed self-assembled nanopeptides that penetrate cells and target intracellular bacterial infections, which are increasingly difficult to treat due to antibiotic resistance. Learn more in
#ScienceAdvances
:
scim.ag/414fw2q
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Self-assembling peptide with dual function of cell penetration and antibacterial as a nano weapon to combat intracellular bacteria
A nanopeptide with “rapid reach” and “lethal strike” capabilities is identified as an executioner of intracellular bacteria.
https://scim.ag/414fw2q
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If you are working in Extracellular vesicles and metastasis you may want to submit your work to this special issue on EVs in Clinical Experimental Metastasis Journal (Official Journal of the Metastasis Research Society)
link.springer.com/collections/...
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Extracellular vesicles and Metastatic Disease
This collection focuses on the role of extracellular vesicles (EVs) in tumor progression and metastasis. EVs are increasingly recognized as key mediators of ...
https://link.springer.com/collections/fhdgcfihfc
8 months ago
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Hector Peinado
Waggoner Lab
8 months ago
Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
www.cell.com/cell-reports...
@cp-cellreports.bsky.social
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Sexta edición del curso Online GEIVEX/UFV MOOCS en español -
geivex.org/outreach/new...
- Un año más tenemos el Curso de Especialización en Vesículas Extracelulares online.
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Sexta edición del curso Online GEIVEX/UFV MOOCS en español – Geivex
GEIVEX is a working group of Spanish researchers specialized in the field of extracellular vesicles.
https://geivex.org/outreach/news/sexta-edicion-del-curso-online-geivex-ufv-moocs-en-espanol/
8 months ago
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Hector Peinado
9 months ago
Nicholas Fabiano, MD @NTFabiano Academics are paid nothing for peer review. Yet journals made a total of over $8.3 billion on article processing charges alone between 2019-2023. Make it make sense.
x.com/NTFabiano/st...
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x.com
https://x.com/NTFabiano/status/1882585718696063140
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reposted by
Hector Peinado
Chris Stringer
9 months ago
More than 40% of postdocs leave academia, study reveals
www.nature.com/articles/d41...
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More than 40% of postdocs leave academia, study reveals
Publishing highly cited papers helps postdoctoral researchers to land a faculty job.
https://www.nature.com/articles/d41586-025-00142-y
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