xavier salvatella
@xsalvatella1.bsky.social
📤 722
📥 473
📝 37
Scientist at ICREA and IRB Barcelona.
reposted by
xavier salvatella
IRB Barcelona
about 1 month ago
📌 Don't miss our plenary #seminar this week, with Prof. Edward Lemke, from
@unimainz.bsky.social
. Host: Dr.
@xsalvatella1.bsky.social
#seminar
#IRBBarcelona
Register here ➡️
https://shorturl.at/I58yN
🧪
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xavier salvatella
The Francis Crick Institute
3 months ago
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️
www.crick.ac.uk/careers-stud...
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Giulio Tesei
3 months ago
I'm hiring for a PhD position at Malmö University, Sweden! The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes. More details and application form:
tinyurl.com/4zm92365
Please feel free to share!
@vetenskapsradet.bsky.social
|
@mau.se
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Thank you Fundación
@bbvaenespana.bsky.social
for supporting our collaboration with Michael Krieg of
@icfo.eu
!
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3 months ago
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xavier salvatella
The New Yorker
3 months ago
Antoni Gaudí’s vision for the Sagrada Família, a church that’s been under construction for nearly 150 years, was never universally liked. George Orwell called the church “one of the most hideous buildings in the world.”
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Is the Sagrada Família a Masterpiece or Kitsch?
In the century since Antoni Gaudí died, his wild design has been obsessively realized, creating the world’s tallest church—and an endlessly debated icon.
https://www.newyorker.com/magazine/2025/09/22/is-the-sagrada-familia-a-masterpiece-or-kitsch?utm_medium=social&utm_social-type=owned&utm_source=bluesky&mbid=social_bluesky&utm_brand=tny
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xavier salvatella
Nature
4 months ago
RFK Jr has vowed to find out what’s responsible for the rise in autism diagnoses, but scientists say he is ignoring answers from decades of research
go.nature.com/47R4brs
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Autism is on the rise: what’s really behind the increase?
Nature - RFK Jr has vowed to find out what’s responsible, but scientists say he is ignoring answers from decades of research.
https://go.nature.com/47R4brs
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xavier salvatella
Alex Holehouse
4 months ago
Are you a computational biologist who loves the outdoors & is thinking about faculty positions? Then check this out:
eeik.fa.us2.oraclecloud.com/hcmUI/Candid...
Tenure track position at the University of Wyoming - amazing colleagues, beautiful landscape, and fantastic work-life balance.
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Asst Professor - Molecular Biology - Computational Biochemist
The Department of Molecular Biology (MOLB) and the School of Computing (SoC) at the University of Wyoming seeks candidates for a tenure-track position at the rank of Assistant Professor starting in th...
https://eeik.fa.us2.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1/job/252589/?utm_medium=jobshare&utm_source=External+Job+Share
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xavier salvatella
Tanja Mittag
6 months ago
New paper on transcription factor phase separation published from my colleague Aseem Ansari's and my lab: Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function
authors.elsevier.com/sd/article/S...
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xavier salvatella
Centre de Regulació Genòmica (CRG)
6 months ago
Exciting news: our Board of Trustees has appointed
@monicabettencourt.bsky.social
as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...
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xavier salvatella
RSC-ESR Group
6 months ago
Congratulations to RSC-ESR group committee member Adam Brookfield and his colleague, Dr Muralidharan Shanmugam, for winning the RSC Technical Excellence Prize for their operations of the EPSRC NRF for EPR in Manchester, UK.
www.manchester.ac.uk/about/news/f...
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Four University colleagues win prestigious Royal Society of Chemistry prizes
Four University of Manchester colleagues have been honoured by the Royal Society of Chemistry for their outstanding contributions to the chemical sciences.Professor Igor Larrosa has been selected to r...
https://www.manchester.ac.uk/about/news/four-university-colleagues-win-prestigious-royal-society-of-chemistry-prizes/
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xavier salvatella
IRB Barcelona
6 months ago
🏆 La investigación sobre la causa del #autismo, premio #VanguardiadelaCiencia 2025! ¡Enhorabuena a las premiadas: Dra. Carla Garcia Cabau y Dra. Anna Bartomeu, del #IRBBarcelona!👏👏👏 ➡️ https://shorturl.at/1hXF0
@lavanguardia.com
@xsalvatella1.bsky.social
🧪
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xavier salvatella
Nature Biotechnology
6 months ago
Today’s uniquely challenging biotech climate may result in a more resilient sector
nature.com/articles/s41...
rdcu.be/etg7h
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Biotech financing: divide and reset - Nature Biotechnology
Today’s uniquely challenging biotech climate may result in a more resilient sector.
https://nature.com/articles/s41587-025-02723-8
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xavier salvatella
Derek Lowe
6 months ago
“What is common knowledge in your field, but shocks outsiders?” Most drugs have several activities in the human body, and discovery of these effects goes on for years after they are on the market.
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xavier salvatella
Philip Ball
6 months ago
...the amino-acid sequence does not necessarily determine 3D shape, because many of our proteins have functionally crucial disordered regions that don't really have a shape. (Sometimes they fold on binding, perhaps in a ligand-specific way, sometimes they don't.)...
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xavier salvatella
Rachel W. Martin
6 months ago
Here's an anniversary worth celebrating!
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xavier salvatella
Stan Stanminson
7 months ago
Patent departments have budget targets that lead to “pound foolish” decisions to abandon all the time.
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xavier salvatella
IDPSeminars
7 months ago
IDPSeminars is back with another seminar this week from
@sarahshammas.bsky.social
and
@sonia-longhi.bsky.social
! Come hear about transcriptional regulation and viral pathogenesis! Thursday June 5th! PST 10 am EST 1 pm CET 7 pm! Info:
idpseminars.com
Signup form:
forms.gle/3yCHeYvuuqLh...
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xavier salvatella
Max Planck Institute for Molecular Genetics
8 months ago
Nuage Therapeutics, co-founded by our group leader Denes Hnisz was highlighted in recent Nature Spotlight article:
www.nature.com/articles/d42...
Find out more about work in the Hnisz lab:
www.molgen.mpg.de/3857230/tran...
@irbbarcelona.org
@xsalvatella1.bsky.social
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xavier salvatella
Pedro Beltrao
8 months ago
The Gulbenkian Institute of Molecular Medicine (GIMM) is one of the best research institutes in Portugal. It's currently recruiting for three Group Leaders (junior or senior) across different areas, including systems biology and bioinformatics.
gimm.pt/jobs/open-ca...
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Research Group Leaders – GIMMResearch Group Leaders – GIMM
Thank you very much for your generous donation and for sharing your testimony.We hope to more people feel inspired to join this mission of discovery and innovation!
https://gimm.pt/jobs/open-call-research-group-leaders
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xavier salvatella
Ylva Ivarsson
8 months ago
Looking for a senior lecturer (associate
#professor
) position in
#biochemistry
? Come and join our neighbouring department at Uppsala University:
www.uu.se/en/about-uu/...
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Senior lecturer in medical biochemistry - Uppsala University
Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University
https://www.uu.se/en/about-uu/join-us/jobs-and-vacancies/job-details?query=807098
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reposted by
xavier salvatella
@CDTI_innovacion
8 months ago
📢La SICC
#Innvierte
del CDTI Innovación invierte, junto con @SofinnovaVC, en Nuage TX,
#startup
que desarrolla nuevos 🧪#fármacos ➡️
acortar.link/3Zc7lg
#AyudasCDTI
#innovación
#pymes
#tecnología
#coinversiones
#CapitalRiesgo
#salud
#oncología
#cáncer
#terapia
#Agenda2030
#ODS3
#AyudandoCrearFuturo
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xavier salvatella
Kresten Lindorff-Larsen
8 months ago
The Structural Biology and NMR Laboratory—or SBiNLab as we call it—is turning 25 🎉🧲🇩🇰 We're celebrating with a symposium on Aug. 23 that is free and open to all Great speakers incl. Ad Bax, Frauke Gräter, Harald Schwalbe, Sarah Shammas, Mikael Akke & alumni! Join us:
www1.bio.ku.dk/english/rese...
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xavier salvatella
Yolanda Perez
8 months ago
Looking for a postdoc in the beautiful city of Barcelona? Are you interested in biocatalysis, enzymes, structural biology (NMR, SAXS, etc.) and sustainable chemistry? The Biotransformation team (PIs Prof. Pere Clapés and myself) is looking for candidates to apply for the MSCA-PF 2025 call (1/2)⏬
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xavier salvatella
Trends in Biochemical Sciences
8 months ago
Online now - a tribute to the memory of Prof. Joan J. Guinovart from Jordi Duran and Matthew Gentry. Prof. Guinovart was a renowned biochemist in the field of glycogen metabolism and known for his leadership in science. (1/4)
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xavier salvatella
Nature
8 months ago
Nature research paper: Low overlap of transcription factor DNA binding and regulatory targets
https://go.nature.com/4jedGUz
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Low overlap of transcription factor DNA binding and regulatory targets - Nature
A near-complete survey of transcription factor activities in Saccharomyces cerevisiae reveals that most transcription factors have both activator and repressor activities and limited overlap between their binding sites on DNA and regulation of nearby genes.
https://go.nature.com/4jdgSQa
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xavier salvatella
CERM/CIRMMP Infrastructure
9 months ago
🚨New research!
#NMR
study reveals hidden interplay between ordered and disordered regions in the CBP TAZ4 construct—shedding light on complexity often missed by traditional
#structuralbiology
Read more about this research conducted under the
#ITACA.SB
project!
@instruct-eric.bsky.social
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Decoding Order and Disorder in Proteins by NMR Spectroscopy
Proteins often have a complex architecture, consisting of both globular ordered domains and intrinsically disordered regions (IDRs). These multidomain proteins pose challenges for traditional structur...
https://pubs.acs.org/doi/10.1021/jacs.4c14959
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xavier salvatella
Rohit V. Pappu
9 months ago
We investigated the interfacial orientations of scaffold molecules vs. adsorbents in model condensates formed by pairs of RNA molecules with PEG. Experiments identify purine-rich RNAs as scaffolds & pyrimidine-rich RNAs as adsorbents that undergo wetting transitions.
www.nature.com/articles/s41...
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Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates - Nature Communications
Experiments and computations show that the organization and dynamics of molecules within and at interfaces of biomolecular condensates are governed by differential interaction strengths leading to the...
https://www.nature.com/articles/s41467-025-58736-z
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xavier salvatella
IRB Barcelona
9 months ago
Join us in our plenary #seminar tomorrow, with Prof. Ben Schuler, from the University of Zurich. Hosted by Dr.
@xsalvatella1.bsky.social
Save your spot now ➡️
https://shorturl.at/tflid
🧪
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xavier salvatella
Nature Portfolio
9 months ago
Individuals who were conceived in colder seasons are more likely to show higher brown adipose tissue activity, increased energy expenditure and a lower BMI, and lower fat accumulation around internal organs, suggests a study in Nature Metabolism.
https://go.nature.com/4i3EYM0
🧪
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So looking forward to this !
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9 months ago
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xavier salvatella
Jean-Philip Piquemal
9 months ago
#compchemsky
A change of paradigm in the use of MD is required. Trajectories should be stored under FAIR requirements to favor its reuse by the community under an open science paradigm. Happy to be part of this letter, now out
@naturemethods.bsky.social
#biosky
www.nature.com/articles/s41...
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The need to implement FAIR principles in biomolecular simulations - Nature Methods
In the Big Data era, a change of paradigm in the use of molecular dynamics is required. Trajectories should be stored under FAIR (findable, accessible, interoperable and reusable) requirements to favo...
https://www.nature.com/articles/s41592-025-02635-0
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xavier salvatella
Protein Society
9 months ago
Our March newsletter is hot off the press and FULL of great information: our 2025 Award winners, our 2024 Best Paper winners, the introduction of our new Protein Society Fellows program, PS39 Symposium information, and MORE!
mailchi.mp/092ac32c4994...
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xavier salvatella
Magnetic Resonance News
9 months ago
Lund University, Sweden, is recruiting an Assistant Professor in Biophysical Chemistry with a focus on NMR Spectroscopy
lu.varbi.com/en/what:job/...
#NMRjobs
#NMRchat
#NMR
#chemsky
🧲
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Assistant Professor in Biophysical Chemistry with a focus on NMR Spectroscopy
The Chemistry Department at Lund University, Faculty of Engineering invites applications for a position as Assistant Professor in Biophysical Chemistry with a focus on NMR Spectroscopy. Description of
https://lu.varbi.com/en/what:job/jobID:798803/#NMRjobs
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xavier salvatella
Olalla Vázquez
10 months ago
🔊 ‼️Last days to apply for
#PhD
position to combat climate change in a Max Planck & University Consortium 📅 Deadline 09.03 📅 We are looking for chemistry students with a strong multi-step synthesis background in organic chemistry. Application online 📩 Please RT - Thanks!
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xavier salvatella
Rohit V. Pappu
10 months ago
www.biorxiv.org/content/10.1...
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Molecular grammars of intrinsically disordered regions that span the human proteome
Intrinsically disordered regions (IDRs) of proteins are defined by functionally relevant molecular grammars. This refers to IDR-specific non-random amino acid compositions and non-random patterning of...
https://www.biorxiv.org/content/10.1101/2025.02.27.640591v1
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xavier salvatella
Doug Kojetin
10 months ago
Now published! Read our newest story!
doi.org/10.1038/s414...
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Yolanda Perez
10 months ago
The Specialised Group of NMR of the Spanish Royal Society of Chemistry (GERMN-RSEQ) is pleased to announce the XVI International Manuel Rico NMR School.
#NMRchat
🗓️1st to 6th June 2025 ⛰️Jaca (Spain)
germn.rseq.org/actividades1...
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International Manuel Rico NMR School – GERMN
Throughout its editions, this wellestablished course organized by the specialized Nuclear Magnetic Resonance (NMR) group of the RSEQ (GERMN) has become an excellent platform for improving the underst...
https://germn.rseq.org/actividades1/nmr-summer-school/
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xavier salvatella
IRB Barcelona
11 months ago
🧪 Join us in our Research Nodes #Seminar next week, with Prof.
@paulrobustelli.bsky.social
, from Dartmouth College. Host: Dr.
@xsalvatella1.bsky.social
Register here ➡️
https://tinyurl.com/awn8t2xm
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xavier salvatella
Jason Zhang 🏳️🌈🇺🇸
11 months ago
Excited to share my recent work on designing new Hsp70 activators to regulate condensates, and thus reveal their functions:
www.sciencedirect.com/science/arti...
@uwproteindesign.bsky.social
@cp-cellchembiol.bsky.social
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De novo designed Hsp70 activator dissolves intracellular condensates
Protein quality control (PQC) is carried out in part by the chaperone Hsp70 in concert with adapters of the J-domain protein (JDP) family. The JDPs, a…
https://www.sciencedirect.com/science/article/pii/S2451945625000297
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xavier salvatella
Philip Ball
11 months ago
In the cover story of the February issue of
@sciam.bsky.social
I explain what biomolecular condensates are and why they are transforming cell biology. A short 🧵 (You'll need a subscription to read the article.)
www.scientificamerican.com/article/myst...
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Mysterious Blobs in Cells Are Changing the Way We Understand Life
Tiny specks called biomolecular condensates are leading to a new understanding of the cell
https://www.scientificamerican.com/article/mysterious-blobs-found-in-cells-are-rewriting-how-life-works/
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xavier salvatella
Rohit V. Pappu
11 months ago
@philipcball.bsky.social
lhttps://www.scientificamerican.com/article/mysterious-blobs-found-in-cells-are-rewriting-how-life-works/
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xavier salvatella
IRB Barcelona
11 months ago
🧪 Don't miss our extraordinary Research Nodes #seminar this week, with Dr. Alexander Buell, from the Denmark Technical University (DTU). Host: Dr.
@xsalvatella1.bsky.social
Register here ➡️ https://s.mtrbio.com/uzxqxnzvng
#BarcelonaBiomed
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xavier salvatella
Jaume Collboni
11 months ago
Les descobertes de
@irbbarcelona.org
milloren la vida de persones de tot el món. Són esperança, referent i un orgull per la ciutat. Avui he agraït i encoratjat al personal investigador en la seva tasca.
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Very nice Spotlight by JR Huang on our recent paper on the link between CPEB4 aggregation and ASD : Microexon in action: How tiny fragments in a protein tune function, drive disease: Molecular Cell
www.cell.com/molecular-ce...
. Thank you for highlighting our work !
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Microexon in action: How tiny fragments in a protein tune function, drive disease
Intrinsically disordered regions (IDRs) of proteins can regulate function through phase separation. In a recent article in Nature, Garcia-Cabau et al. reveal that including or excluding a microexon wi...
https://www.cell.com/molecular-cell/fulltext/S1097-2765%2824%2901040-2
11 months ago
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Katja Petzold
11 months ago
Interested in computational NMR? Join us in beautiful Switzerland in June! Many slots for selected talks and great hiking opportunities. GRC conference 1-6th of June with GRS (
@chrisdkolloff.bsky.social
and Stase) on 30.05. please share
@nmr900.bsky.social
www.grc.org/computationa...
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xavier salvatella
Alex Holehouse
11 months ago
New review / perspective with
@albertilab-tud.bsky.social
on our thoughts on condensate speciality and recruitment, focusing on interplay between site specific and chemically specific interactions
www.cell.com/molecular-ce...
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Molecular determinants of condensate composition
Biomolecular condensates are non-stochiometric assemblies that organize cellular matter in space and time. Despite much work, many questions remain regarding what determines the recruitment and exclus...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)01039-6
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xavier salvatella
Arne Schneuing
11 months ago
Our paper on computational design of chemically induced protein interactions is out in
@natureportfolio.bsky.social
. Big thanks to all co-authors, especially Anthony Marchand, Stephen Buckley and Bruno Correia!
t.co/vtYlhi8aQm
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xavier salvatella
IRB Barcelona
12 months ago
📌 Don't miss our Research Nodes #seminar this week, with Dr.
@lindorfflarsen.bsky.social
, from the #LinderstrømLang Centre for Protein Science (Denmark)👇 🤝 Hosted by Dr.
@xsalvatella1.bsky.social
Register now! ➡️ shorturl.at/Q1LVA
#BarcelonaBiomed
🧪
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Looking forward to hosting you at
@irbbarcelona.org
!
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12 months ago
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