xavier salvatella
@xsalvatella1.bsky.social
📤 758
📥 512
📝 41
Scientist at ICREA and IRB Barcelona.
reposted by
xavier salvatella
Magnetic Resonance News
13 days ago
Memorial Minute for Martin Karplus - Harvard Gazette
news.harvard.edu/gazette/stor...
#NMRchat
🧲
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Memorial Minute for Martin Karplus — Harvard Gazette
At a meeting of the Faculty of Arts and Sciences on May 5, 2026, the following tribute to the life and service of the late Martin Karplus was spread upon the permanent records of the Faculty.
https://news.harvard.edu/gazette/story/2026/05/martin-karplus-94/
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xavier salvatella
Raimon Sunyer
14 days ago
Interested in molecular motors? Don’t miss this wonderful symposium in Salamanca on "The Structure and Workings of Molecular Machines" with an outstanding lineup of speakers. 📍 Salamanca, Spain 📅 Monday, June 22, 2026 🎟️ Attendance is free, but registration is required 👇👇👇
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xavier salvatella
Magnetic Resonance News
13 days ago
4th Workshop on Structural Biophysics, October 12-16, 2026, Bordeaux, France, registration closes May 19
www.cbmn.u-bordeaux.fr/ivth-worksho...
#NMRchat
🧲
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IVth Workshop on Structural Biophysics. - CBMN
5 jours de Workshop en Biophysique à Bordeaux ! Les techniques en biophysique permettent d’appréhender les mécanismes d’interactions entre entités biomoléculaires à une échelle allant de la taille de ...
https://www.cbmn.u-bordeaux.fr/ivth-workshop-on-structural-biophysics-2/
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xavier salvatella
Junjie Guo
13 days ago
Check out the phenomenal PhD work by Katie Copley, a current postdoc in our lab
@yaleneuro.bsky.social
@yalerna.bsky.social
.
www.science.org/doi/10.1126/...
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Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
Aberrant aggregation of the prion-like RNA binding protein TDP-43 drives several fatal neurodegenerative proteinopathies, including amyotrophic lateral sclerosis (ALS). In this work, we define how sho...
https://www.science.org/doi/10.1126/science.adv3301
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xavier salvatella
Department of Chemistry, Stanford University
21 days ago
Join Stanford Chem for this year's McConnell Lecturer in Chem: Prof. Lewis E. Kay (Univ. of Toronto), a pioneer in biomolecular NMR. He’ll present “The Essentiality of Solution NMR Spectroscopy in the Post-Alpha Fold Era,” May 5, 3–4 PM, Sapp Center 114.
chemistry.stanford.edu/events/mccon...
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xavier salvatella
IRB Barcelona
29 days ago
🧬 Mutations in the "translators" of the human cell alter the reading of the genetic code in #cancer and #aging. ✍️ Lluís Ribas (#IRBBarcelona) et al. 📰
@genomeresearch.bsky.social
#cancer
#aging.
#IRBBarcelona)
ead more ➡️ https://shorturl.at/5pk2P 📌 DOI: 10.1101/gr.281022.125
#IRBScience
#AgeingResearch
#AgingResearch
🧪
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xavier salvatella
Mohammed AlQuraishi
about 1 month ago
Does AlphaFold’s latent space encode only the native state or something like a distribution over conformations? We begin to answer this question with ConforNets, a mechanism for producing diverse states, or very specific ones, via inference-time adaption of OF3p’s latent space👇
add a skeleton here at some point
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xavier salvatella
BIST-Barcelona Institute of Science and Technology
about 1 month ago
El nou edifici que acolllirà grups de recerca de 5 centres
#BISTCommunity
i enfocat en medicina de precisió va prenent forma. 👉https://www.ara.cat/societat/horitzo-2028-gran-hub-biomedicina-sud-d-europa-pren-forma_1_5702563.html?giveAway=uCQdvPiwpW4GkqLE
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xavier salvatella
IRB Barcelona
about 1 month ago
🔬A new mechanism explains how protein production is regulated in #FattyLiver under metabolic stress. 📰 Science Advances ✍️ Raúl Méndez, Eulàlia Belloc, Vittorio Calderone, Mercedes Fernández,
@idibaps.bsky.social
@ptck72.bsky.social
et al. ➡️
https://shorturl.at/UtRVB
📌 DOI: 10.1126/sciadv.aea4125
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xavier salvatella
Kazuhiro Maeshima
about 1 month ago
Our linker histone H1 paper is featured on the cover of the April 10 issue of
#ScienceAdvances
.
www.science.org/doi/10.1126/...
A molecular dynamics simulation of nucleosomes and linker histone H1, with single-H1 trajectories (background). 🎉 Full cover caption:
www.science.org/toc/sciadv/1...
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xavier salvatella
Kresten Lindorff-Larsen
2 months ago
We are hiring a postdoc in computational biophysics and machine learning studies of intrinsically disordered proteins We aim to study the function of IDPs by combining CG MD, ML and bioinformatics in collaboration with
@tanjamittag.bsky.social
&
@rhp-lab.bsky.social
tinyurl.com/REWIRE-PD
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xavier salvatella
IRB Barcelona
about 2 months ago
📢 We are
#hiring
!
#GroupLeader
positions open at
#IRBBarcelona
in
#ChemicalBiology
and
#StructuralBiology
. Application deadline: May 22, 2026 𝗚𝗿𝗼𝘂𝗽 𝗟𝗲𝗮𝗱𝗲𝗿 𝗶𝗻 𝗖𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗕𝗶𝗼𝗹𝗼𝗴𝘆 ➡️
shorturl.at/1tE3n
𝗚𝗿𝗼𝘂𝗽 𝗟𝗲𝗮𝗱𝗲𝗿 𝗶𝗻 𝗦𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗮𝗹 𝗕𝗶𝗼𝗹𝗼𝗴𝘆 ➡️
shorturl.at/eKiJn
#IRBJobs
#Jobs
#AcademicSky
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reposted by
xavier salvatella
about 2 months ago
#paper
#highlight
February 2026 Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule By S. Bielskutė-García et al in
#ScienceAdvances
sbe.es/highlights-p..
.
@xsalvatella1.bsky.social
@irbbarcelona.org
@icreacommunity.bsky.social
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xavier salvatella
IRB Barcelona
about 2 months ago
📢 Upcoming Seminar | Join us for a plenary seminar this Friday, with Dr.
@adelaljord.bsky.social
, from the
@crg.eu
. 🤝 Hosted by Dr.
@xsalvatella1.bsky.social
Register here ➡️ https://shorturl.at/A9VMZ
#IRBBarcelona
#Seminar
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Happy to announce that my institution,
@irbbarcelona.org
, is opening two group leader positions, 1 in chemical biology and 1 in structural biology, to strengthen our expertise in molecular sciences: please spread the word !
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2 months ago
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Our work on how oligomerization can enable selectively targeting intrinsic disorder with small molecules is now out in Science Advances:
www.science.org/doi/10.1126/...
). Congratulations Stase Bielskute and
@borjaml.bsky.social
and thanks to the collaborators and funders !
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Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule
The druggability of intrinsically disordered regions.
https://www.science.org/doi/10.1126/sciadv.adz7400
2 months ago
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reposted by
xavier salvatella
IDPSeminars
3 months ago
IDPSeminars is back TOMORROW! Come see
@tanjamittag.bsky.social
and
@xsalvatella1.bsky.social
! Not to be missed!!
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reposted by
xavier salvatella
The EMBO Journal
3 months ago
Yeast ubiquilin Dsk2 scaffolds proteasome-containing condensates under stress via multivalent interactions –
@castanedalab.bsky.social
et al show how dynamic interactions among its STI1 domain & transient helices in its disordered region promote its phase-separation
link.springer.com/article/10.1...
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STI1 domain engages transient helices to mediate Dsk2 phase separation and proteasome condensation - The EMBO Journal
Ubiquitin-binding shuttle proteins are important components of stress-induced biomolecular condensates in cells. Yeast Dsk2 scaffolds proteasome-containing condensates via multivalent interactions wit...
https://link.springer.com/article/10.1038/s44318-026-00696-1
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reposted by
xavier salvatella
Emmanuel Levy's lab
3 months ago
In 2017 we showed that homomers evolve on the edge of supramolecular self-assembly. Here we show how to exploit this vulnerability so that ALL homomers can become bona fide drug-🎯. Delighted that Aim 3 of our
@erc.europa.eu
finally polymerized! Manuscript: 👉
rdcu.be/e27bT
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An excellent review on a fascinating topic !
add a skeleton here at some point
3 months ago
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xavier salvatella
Biophysical Society
4 months ago
Join 2026 BPS Lecturer Lewis Kay on Tuesday, February 24, 2:00 PM - 3:00 PM at
#bps2026
for an informal discussion. Dr. Kay will share insights from his scientific career—from pioneering discoveries to lessons learned along the way—and reflect on how the field continues to evolve
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xavier salvatella
IRB Barcelona
4 months ago
📢 #MAINFRAME Symposium comes to Barcelona! Experts in #AI, computational chemistry & small-molecule #DrugDiscovery meet to advance open, large-scale screening for 2,000+ human proteins. 📆 Mar 18–19 📍 Ateneu Barcelonès ℹ️ https://shorturl.at/1aKKS
@ptck72.bsky.social
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xavier salvatella
Alejo Rodriguez-Fraticelli
4 months ago
🚨WE'RE RECRUITING AT
@irbbarcelona.org
!!!! --- ADVANCED GENOMICS FACILITY MANAGER --- An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!! APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
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Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona
IRB Barcelona invites applications for the position of Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the Director, Technology Strateg...
https://recruitment.irbbarcelona.org/jobs/7124180-head-advanced-genomics-technologies-core-facility-ref-cf-26-01
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xavier salvatella
Jerelle Joseph
4 months ago
How does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social
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xavier salvatella
IRB Barcelona
4 months ago
You can’t miss this video we shared today during the tribute to Dr.
#JoanGuinovart
. Today, the scientific community, institutional leaders, colleagues, friends, and family gathers to honour the life and legacy of the founder and first director of
#IRBBarcelona
. 🎥
youtu.be/_SJ5Rudj2ik
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16 de enero de 2026
YouTube video by IRB Barcelona
https://youtu.be/_SJ5Rudj2ik
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xavier salvatella
IRB Barcelona
6 months ago
📌 Don't miss our plenary #seminar this week, with Prof. Edward Lemke, from
@unimainz.bsky.social
. Host: Dr.
@xsalvatella1.bsky.social
#seminar
#IRBBarcelona
Register here ➡️
https://shorturl.at/I58yN
🧪
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reposted by
xavier salvatella
The Francis Crick Institute
7 months ago
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️
www.crick.ac.uk/careers-stud...
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xavier salvatella
Giulio Tesei
8 months ago
I'm hiring for a PhD position at Malmö University, Sweden! The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes. More details and application form:
tinyurl.com/4zm92365
Please feel free to share!
@vetenskapsradet.bsky.social
|
@mau.se
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Thank you Fundación
@bbvaenespana.bsky.social
for supporting our collaboration with Michael Krieg of
@icfo.eu
!
add a skeleton here at some point
8 months ago
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xavier salvatella
The New Yorker
8 months ago
Antoni Gaudí’s vision for the Sagrada Família, a church that’s been under construction for nearly 150 years, was never universally liked. George Orwell called the church “one of the most hideous buildings in the world.”
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Is the Sagrada Família a Masterpiece or Kitsch?
In the century since Antoni Gaudí died, his wild design has been obsessively realized, creating the world’s tallest church—and an endlessly debated icon.
https://www.newyorker.com/magazine/2025/09/22/is-the-sagrada-familia-a-masterpiece-or-kitsch?utm_medium=social&utm_social-type=owned&utm_source=bluesky&mbid=social_bluesky&utm_brand=tny
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xavier salvatella
Nature
9 months ago
RFK Jr has vowed to find out what’s responsible for the rise in autism diagnoses, but scientists say he is ignoring answers from decades of research
go.nature.com/47R4brs
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Autism is on the rise: what’s really behind the increase?
Nature - RFK Jr has vowed to find out what’s responsible, but scientists say he is ignoring answers from decades of research.
https://go.nature.com/47R4brs
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xavier salvatella
Alex Holehouse
9 months ago
Are you a computational biologist who loves the outdoors & is thinking about faculty positions? Then check this out:
eeik.fa.us2.oraclecloud.com/hcmUI/Candid...
Tenure track position at the University of Wyoming - amazing colleagues, beautiful landscape, and fantastic work-life balance.
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Asst Professor - Molecular Biology - Computational Biochemist
The Department of Molecular Biology (MOLB) and the School of Computing (SoC) at the University of Wyoming seeks candidates for a tenure-track position at the rank of Assistant Professor starting in th...
https://eeik.fa.us2.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1/job/252589/?utm_medium=jobshare&utm_source=External+Job+Share
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xavier salvatella
Tanja Mittag
11 months ago
New paper on transcription factor phase separation published from my colleague Aseem Ansari's and my lab: Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function
authors.elsevier.com/sd/article/S...
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xavier salvatella
Centre de Regulació Genòmica (CRG)
11 months ago
Exciting news: our Board of Trustees has appointed
@monicabettencourt.bsky.social
as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...
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xavier salvatella
RSC-ESR Group
11 months ago
Congratulations to RSC-ESR group committee member Adam Brookfield and his colleague, Dr Muralidharan Shanmugam, for winning the RSC Technical Excellence Prize for their operations of the EPSRC NRF for EPR in Manchester, UK.
www.manchester.ac.uk/about/news/f...
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Four University colleagues win prestigious Royal Society of Chemistry prizes
Four University of Manchester colleagues have been honoured by the Royal Society of Chemistry for their outstanding contributions to the chemical sciences.Professor Igor Larrosa has been selected to r...
https://www.manchester.ac.uk/about/news/four-university-colleagues-win-prestigious-royal-society-of-chemistry-prizes/
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xavier salvatella
IRB Barcelona
11 months ago
🏆 La investigación sobre la causa del #autismo, premio #VanguardiadelaCiencia 2025! ¡Enhorabuena a las premiadas: Dra. Carla Garcia Cabau y Dra. Anna Bartomeu, del #IRBBarcelona!👏👏👏 ➡️ https://shorturl.at/1hXF0
@lavanguardia.com
@xsalvatella1.bsky.social
🧪
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reposted by
xavier salvatella
Nature Biotechnology
11 months ago
Today’s uniquely challenging biotech climate may result in a more resilient sector
nature.com/articles/s41...
rdcu.be/etg7h
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Biotech financing: divide and reset - Nature Biotechnology
Today’s uniquely challenging biotech climate may result in a more resilient sector.
https://nature.com/articles/s41587-025-02723-8
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xavier salvatella
Derek Lowe
11 months ago
“What is common knowledge in your field, but shocks outsiders?” Most drugs have several activities in the human body, and discovery of these effects goes on for years after they are on the market.
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xavier salvatella
Philip Ball
11 months ago
...the amino-acid sequence does not necessarily determine 3D shape, because many of our proteins have functionally crucial disordered regions that don't really have a shape. (Sometimes they fold on binding, perhaps in a ligand-specific way, sometimes they don't.)...
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xavier salvatella
Rachel W. Martin
11 months ago
Here's an anniversary worth celebrating!
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xavier salvatella
Stan Stanminson
12 months ago
Patent departments have budget targets that lead to “pound foolish” decisions to abandon all the time.
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xavier salvatella
IDPSeminars
12 months ago
IDPSeminars is back with another seminar this week from
@sarahshammas.bsky.social
and
@sonia-longhi.bsky.social
! Come hear about transcriptional regulation and viral pathogenesis! Thursday June 5th! PST 10 am EST 1 pm CET 7 pm! Info:
idpseminars.com
Signup form:
forms.gle/3yCHeYvuuqLh...
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reposted by
xavier salvatella
Max Planck Institute for Molecular Genetics
about 1 year ago
Nuage Therapeutics, co-founded by our group leader Denes Hnisz was highlighted in recent Nature Spotlight article:
www.nature.com/articles/d42...
Find out more about work in the Hnisz lab:
www.molgen.mpg.de/3857230/tran...
@irbbarcelona.org
@xsalvatella1.bsky.social
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reposted by
xavier salvatella
Pedro Beltrao
about 1 year ago
The Gulbenkian Institute of Molecular Medicine (GIMM) is one of the best research institutes in Portugal. It's currently recruiting for three Group Leaders (junior or senior) across different areas, including systems biology and bioinformatics.
gimm.pt/jobs/open-ca...
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Research Group Leaders – GIMMResearch Group Leaders – GIMM
Thank you very much for your generous donation and for sharing your testimony.We hope to more people feel inspired to join this mission of discovery and innovation!
https://gimm.pt/jobs/open-call-research-group-leaders
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xavier salvatella
Ylva Ivarsson
about 1 year ago
Looking for a senior lecturer (associate
#professor
) position in
#biochemistry
? Come and join our neighbouring department at Uppsala University:
www.uu.se/en/about-uu/...
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Senior lecturer in medical biochemistry - Uppsala University
Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University
https://www.uu.se/en/about-uu/join-us/jobs-and-vacancies/job-details?query=807098
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reposted by
xavier salvatella
Kresten Lindorff-Larsen
about 1 year ago
The Structural Biology and NMR Laboratory—or SBiNLab as we call it—is turning 25 🎉🧲🇩🇰 We're celebrating with a symposium on Aug. 23 that is free and open to all Great speakers incl. Ad Bax, Frauke Gräter, Harald Schwalbe, Sarah Shammas, Mikael Akke & alumni! Join us:
www1.bio.ku.dk/english/rese...
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xavier salvatella
Yolanda Perez
about 1 year ago
Looking for a postdoc in the beautiful city of Barcelona? Are you interested in biocatalysis, enzymes, structural biology (NMR, SAXS, etc.) and sustainable chemistry? The Biotransformation team (PIs Prof. Pere Clapés and myself) is looking for candidates to apply for the MSCA-PF 2025 call (1/2)⏬
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xavier salvatella
Trends in Biochemical Sciences
about 1 year ago
Online now - a tribute to the memory of Prof. Joan J. Guinovart from Jordi Duran and Matthew Gentry. Prof. Guinovart was a renowned biochemist in the field of glycogen metabolism and known for his leadership in science. (1/4)
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reposted by
xavier salvatella
Nature
about 1 year ago
Nature research paper: Low overlap of transcription factor DNA binding and regulatory targets
https://go.nature.com/4jedGUz
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Low overlap of transcription factor DNA binding and regulatory targets - Nature
A near-complete survey of transcription factor activities in Saccharomyces cerevisiae reveals that most transcription factors have both activator and repressor activities and limited overlap between their binding sites on DNA and regulation of nearby genes.
https://go.nature.com/4jdgSQa
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