Human SerRS/SIRT2 complex structure reveals cross regulation between translation and NAD+ metabolism www.biorxiv.org/content/10.1101/2025.09.23.677902v1 #cryoem

Cryo-EM structure of influenza polymerase bound to the cRNA promoter provides insights into the mechanism of virus replication www.biorxiv.org/content/10.1101/2025.09.23.677976v1 #cryoem

Structural basis for a filamentous morpheein model of human cystathionine beta-synthase www.biorxiv.org/content/10.1101/2025.09.24.678195v1 #cryoem

Sphingolipids in Extracellular Vesicles Released From the Skeletal Muscle Plasma Membrane Control Muscle Stem Cell Fate During Muscle Regeneration pubmed.ncbi.nlm.nih.gov/40984725/ #cryoem

gapTrick - Structural characterisation of protein-protein interactions using AlphaFold pubmed.ncbi.nlm.nih.gov/40985612/ #cryoem

Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages increased bedaquiline resistance pubmed.ncbi.nlm.nih.gov/40986343/ #cryoem

In situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper for effector translocation pubmed.ncbi.nlm.nih.gov/40986344/ #cryoem

Particle Restoration: A Novel Image Processing Framework for Improving Real Cryo-EM Image Quality in Single Particle Analysis pubmed.ncbi.nlm.nih.gov/40986588/ #cryoem

Dose-efficient cryo-electron microscopy for thick samples using tilt- corrected scanning transmission electron microscopy pubmed.ncbi.nlm.nih.gov/40987871/ #cryoem

Allosteric pockets in the measles and Nipah virus polymerases: Mechanobiological insights and AI-driven drug discovery opportunities pubmed.ncbi.nlm.nih.gov/40978313/ #cryoem

Cryo-EM structure of the human MON1A-CCZ1-RAB7A complex provides insights into nucleotide exchange mechanism pubmed.ncbi.nlm.nih.gov/40979223/ #cryoem

Structural insights into the Pseudomonas aeruginosa ClpP1•ClpP2 heterocomplex and its interactions with the AAA+ ClpX unfoldase pubmed.ncbi.nlm.nih.gov/40980994/ #cryoem

p-Alkoxy-Substituted Anisomycins with Potent Anti-Trypanosomiasis Activity and Expanded Modes of Action pubmed.ncbi.nlm.nih.gov/40980996/ #cryoem

Structural Insights into RubisCO Dynamics and Pyrenoid Architecture in Chlamydomonas reinhardtii www.biorxiv.org/content/10.1101/2025.09.18.677200v1 #cryoem

The structure of the Human Adenovirus 7 virus-like particles reveals that pentons and core-genome promote hexon-pIIIa interactions during capsid maturation www.biorxiv.org/content/10.1101/2025.09.22.677823v1 #cryoem

CryoEM of ATP-driven dynamics and itraconazole binding in a fungal ABC pump www.biorxiv.org/content/10.1101/2025.09.22.677697v1 #cryoem

Single-sequence deep learning delivers crystal-quality models of covalent K-Ras G12 hotspot complexes www.biorxiv.org/content/10.1101/2025.09.16.676163v1 #cryoem

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-EM micrographs www.biorxiv.org/content/10.1101/2025.09.19.677446v1 #cryoem

Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase pubmed.ncbi.nlm.nih.gov/40975169/ #cryoem

Harnessing Protein Unfolding for Thermosensing: Structural Insights from TRPV3 www.biorxiv.org/content/10.1101/2025.09.17.676191v1 #cryoem

LieOTMap-FFT: A Differentiable Fitting Framework Combining Lie Algebra and FFT-accelerated Optimal Transport for Cryo-EM Maps www.biorxiv.org/content/10.1101/2025.09.18.676986v1 #cryoem

TOR signaling on membranes pubmed.ncbi.nlm.nih.gov/40970512/ #cryoem

Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization pubmed.ncbi.nlm.nih.gov/40971423/ #cryoem

Graph Neural Network and Diffusion Model for Modeling RNA Interatomic Interactions pubmed.ncbi.nlm.nih.gov/40971857/ #cryoem

Structural characterization of five functional states of metabotropic glutamate receptor 8 pubmed.ncbi.nlm.nih.gov/40972528/ #cryoem

Molecular Mechanism of ATP Hydrolysis Catalyzed by p97: A QM/MM Study pubmed.ncbi.nlm.nih.gov/40973036/ #cryoem

Molecular blueprints: Guiding drug discovery through protein structure analysis pubmed.ncbi.nlm.nih.gov/40973406/ #cryoem

The structure-based approaches to computing viral fitness pubmed.ncbi.nlm.nih.gov/40973410/ #cryoem

The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking pubmed.ncbi.nlm.nih.gov/40973728/ #cryoem

Convergent utilization of APN receptor by hedgehog merbecoviruses www.biorxiv.org/content/10.1101/2025.09.16.676546v1 #cryoem

NMR assignments and secondary structure analysis of the eIF1-interacting fragment of human eIF3c www.biorxiv.org/content/10.1101/2025.09.13.675972v1 #cryoem

LieOTMap: A Differentiable Approach to Cryo-EM Fitting via Lie-Theoretic Optimal Transport www.biorxiv.org/content/10.1101/2025.09.16.676533v1 #cryoem

RobPicker: A Meta Learning Framework for Robust Identification of Macromolecules in Cryo-Electron Tomograms www.biorxiv.org/content/10.1101/2025.09.16.676650v1 #cryoem

LieMap: A Fast and Transparent Gradient-Based Method for Cryo-EM Structure Fitting www.biorxiv.org/content/10.1101/2025.09.16.676663v1 #cryoem

In situ structure determination of Respiratory Supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane. www.biorxiv.org/content/10.1101/2025.09.19.677273v1 #cryoem

Rapid elicitation of a new class of neutralizing N332-glycan independent V3-glycan antibodies against HIV-1 in nonhuman primates pubmed.ncbi.nlm.nih.gov/40964314/ #cryoem

Structural Basis of Cold and Menthol Sensing by TRPM8 pubmed.ncbi.nlm.nih.gov/40964340/ #cryoem

Identification of a broad and potent V3 glycan site bNAb targeting an N332 gp120 glycan-independent epitope pubmed.ncbi.nlm.nih.gov/40964353/ #cryoem

CryoDataBot: a pipeline to curate cryoEM datasets for AI-driven structural biology pubmed.ncbi.nlm.nih.gov/40964354/ #cryoem

Cryo-EM structure of a methanogen nitrogenase-PII protein supercomplex pubmed.ncbi.nlm.nih.gov/40964395/ #cryoem

Proton Transfer through a Charged Conduit in Respiratory Complex I: Long-Range Effects and Conformational Gating pubmed.ncbi.nlm.nih.gov/40964828/ #cryoem

Cryo-EM structure of the prohibitin complex in open conformation pubmed.ncbi.nlm.nih.gov/40966277/ #cryoem

Mechanistic insights into RAD51-mediated nucleosome binding and remodeling in homologous recombination pubmed.ncbi.nlm.nih.gov/40967099/ #cryoem

Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2 pubmed.ncbi.nlm.nih.gov/40968163/ #cryoem

Correlative MS Imaging for cellular identification and analysis of in situ cryo-ET www.biorxiv.org/content/10.1101/2025.09.16.676641v1 #cryoem

Structure of E. coli Twin-arginine translocase (Tat) complex with bound cargo www.biorxiv.org/content/10.1101/2025.09.16.676506v1 #cryoem

Mapping rRNA, tRNA, and mRNA modifications in ribosomes at high resolution pubmed.ncbi.nlm.nih.gov/40962562/ #cryoem

Building a dynamic model for EGFR-family dimerization using quantitative, live-cell fluorescence methods pubmed.ncbi.nlm.nih.gov/40958417/ #cryoem

Rapaprotin, an Endopeptidase-Activated Proteasome Inhibitor that Induces 26S Disassembly pubmed.ncbi.nlm.nih.gov/40960209/ #cryoem

Disrupting the epigenetic alliance: structural insights and therapeutic strategies targeting DNMT1-UHRF1 pubmed.ncbi.nlm.nih.gov/40960568/ #cryoem