High-resolution structure of proIAPP(1-48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs pubmed.ncbi.nlm.nih.gov/41210656/ #cryoem

C-reactive protein is a broad-spectrum capsule-binding receptor for hepatic capture of blood-borne bacteria pubmed.ncbi.nlm.nih.gov/41214213/ #cryoem

Hydrophilic metformin and hydrophobic biguanides inhibit mitochondrial complex I by distinct mechanisms pubmed.ncbi.nlm.nih.gov/41214295/ #cryoem

Cryo-EM structures of the BAM-P2-visible SurA complex reveal dynamic and cooperative interactions in outer membrane protein assembly www.biorxiv.org/content/10.1101/2025.11.10.687524v1 #cryoem

Division of labor in cargo and membrane recognition by SNX1-SNX5: Insights from multiscale modelling pubmed.ncbi.nlm.nih.gov/41206513/ #cryoem

Future Research Directions on Mycobacterium tuberculosis Proteins pubmed.ncbi.nlm.nih.gov/41207945/ #cryoem

The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation www.biorxiv.org/content/10.1101/2025.11.08.687396v1 #cryoem

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline www.biorxiv.org/content/10.1101/2025.11.08.686982v1 #cryoem

Cryo-EM Structure of FcεRI Bound IgE Reveals Multiple Defined Conformations of the Fab-Fc Hinge pubmed.ncbi.nlm.nih.gov/41199488/ #cryoem

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection pubmed.ncbi.nlm.nih.gov/41201048/ #cryoem

Structural basis of herpesvirus helicase-primase inhibition by pritelivir and amenamevir pubmed.ncbi.nlm.nih.gov/41202142/ #cryoem

Seeing is believing-Plasmodium falciparum translation in action pubmed.ncbi.nlm.nih.gov/41202797/ #cryoem

Structural characterization of zebrafish Ngly2, an ovary-enriched acid PNGase required for egg free glycan production pubmed.ncbi.nlm.nih.gov/41203122/ #cryoem

Molecular mechanisms of the mammalian fatty acid cycle pubmed.ncbi.nlm.nih.gov/41203489/ #cryoem

Molecular architecture and diversity of StopGo/2A translational recoding www.biorxiv.org/content/10.1101/2025.11.07.687186v1 #cryoem

Topological defects drive influenza glycoprotein lattice assembly on spherical membranes www.biorxiv.org/content/10.1101/2025.11.06.686978v1 #cryoem

Axonemal dynein contributions to flagellar beat types and waveforms www.biorxiv.org/content/10.1101/2025.11.06.687033v1 #cryoem

The SPATA5-SPATA5L1-CINP-C1ORF109 complex is essential for cytoplasmic pre-60S ribosome maturation www.biorxiv.org/content/10.1101/2025.11.07.687187v1 #cryoem

Direct and in situ examination of Li+ transport kinetics in an isotope-labeled solid-electrolyte interphase pubmed.ncbi.nlm.nih.gov/41196349/ #cryoem

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination pubmed.ncbi.nlm.nih.gov/41197730/ #cryoem

The Structure and Morphology of Single-Component Oligomeric RNA Delivery Vectors Derived from Amphiphilic Charge-Altering Releasable Transporters pubmed.ncbi.nlm.nih.gov/41194596/ #cryoem

Structural basis for a potent human neutralizing antibody targeting a conserved epitope on the H7 hemagglutinin head pubmed.ncbi.nlm.nih.gov/41196357/ #cryoem

The architecture of membrane structures involved in hepatitis C virus genome replication revealed under close-to-native conditions by cryo-electron tomography pubmed.ncbi.nlm.nih.gov/41196697/ #cryoem

Substituted cysteine modification and protection indicates selective interactions of the anesthetic photolabel pTFD-di-iPr-BnOH with α+/β- and α+/γ- transmembrane subunit interfaces of synaptic GABAA receptors pubmed.ncbi.nlm.nih.gov/41196917/ #cryoem

Cryo-electron microscopy visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2 pubmed.ncbi.nlm.nih.gov/41196948/ #cryoem

Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex pubmed.ncbi.nlm.nih.gov/41196993/ #cryoem

Nanoscale conformational dynamics of human propionyl-CoA carboxylase pubmed.ncbi.nlm.nih.gov/41197621/ #cryoem

Structural basis of isethionate transport by a TRAP transporter from a sulfate-reducing bacterium pubmed.ncbi.nlm.nih.gov/41197622/ #cryoem

Divergent acetyl-CoA binding modes mediate allosteric inhibition of bacterial hybrid-type malic enzymes pubmed.ncbi.nlm.nih.gov/41197718/ #cryoem

Development of an inhibitory TTC7B selective nanobody that blocks EFR3 recruitment of PI4KA pubmed.ncbi.nlm.nih.gov/41197736/ #cryoem

Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat pubmed.ncbi.nlm.nih.gov/41198571/ #cryoem

6-pentadecyl salicylic acid reduces cell proliferation in U373MG glioblastoma cells via glutamine uptake impairment pubmed.ncbi.nlm.nih.gov/41198624/ #cryoem

Extracellular filaments revealed by affinity capture cryogenic-electron tomography pubmed.ncbi.nlm.nih.gov/41198659/ #cryoem

The locking mechanism of human TRPV6 inhibition by intracellular magnesium pubmed.ncbi.nlm.nih.gov/41198662/ #cryoem

A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens pubmed.ncbi.nlm.nih.gov/41198680/ #cryoem

Mechanism of Arp2/3 complex branch disassembly by human Coro7 pubmed.ncbi.nlm.nih.gov/41198690/ #cryoem

Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1 pubmed.ncbi.nlm.nih.gov/41198955/ #cryoem

Architecture of the human KICSTOR and GATOR1-KICSTOR complexes pubmed.ncbi.nlm.nih.gov/41198956/ #cryoem

The molecular basis of μ-opioid receptor signaling plasticity pubmed.ncbi.nlm.nih.gov/41199005/ #cryoem

Sequence-Specific Protein Secondary-Structure Assignment with Isotope Reverse-Labeled Amide I Spectroscopy pubmed.ncbi.nlm.nih.gov/41199128/ #cryoem

Direct Optical Quantification of Chain Collapse, Reduced Dielectric, and Water Release Driving Protein Phase Separation www.biorxiv.org/content/10.1101/2025.11.04.686660v1 #cryoem

Structural snapshots capture nucleotide release at the μ-opioid receptor pubmed.ncbi.nlm.nih.gov/41193810/ #cryoem

Structural insight into Vibrio cholerae EIIC sugar transporter dimer captured in a substrate-free inward-facing state pubmed.ncbi.nlm.nih.gov/41189459/ #cryoem

Xenopus IgX informs engineering strategies of IgM and IgG hexamers pubmed.ncbi.nlm.nih.gov/41191733/ #cryoem

In situ structure of a gap junction-stomatin complex pubmed.ncbi.nlm.nih.gov/41191766/ #cryoem

Structural insights into the atypical filament assembly of pyrin domain-containing IFI16 pubmed.ncbi.nlm.nih.gov/41193640/ #cryoem

Atomically accurate de novo design of antibodies with RFdiffusion pubmed.ncbi.nlm.nih.gov/41193805/ #cryoem

Insights into the multifunctionality of viral glycoproteins F and HN in the lifecycle and pathogenesis of Newcastle disease virus: a systematic review pubmed.ncbi.nlm.nih.gov/41194263/ #cryoem

In situ Architecture of the Tad Pilus Machine in Caulobacter crescentus www.biorxiv.org/content/10.1101/2025.11.05.686773v1 #cryoem

Lessons learned from a Kaggle challenge for particle picking in cryo-electron tomography www.biorxiv.org/content/10.1101/2025.11.03.686153v1 #cryoem