The fact that if you search for something on Google with a typo, it suggests a correct spelling (good!), and you select that spelling to search (also good!), but then click on the search bar, it RETAINS THE WRONG SPELLING is among the most bizarre UI/UX decisions I've seen in many years.

A university that signs the “compact” is one that acknowledges its own inability to compete and succeed based talent and merit. It would signal insecurity and mediocrity to current and future students and faculty. Say no. Recruit the best people, protect their freedom and support their hard work.

Molecular Armor: Simple Rules to Keep Proteins (Re)Soluble💧 Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social www.sciencedirect.com/science/arti...

Humbled to announce that we received a New Innovator award. I thank the NIH’s civil servants for their hard work during a stressful funding cycle. I thank the leadership (and chair, Marc Diamond) at UTSW for betting on my lab’s high risk, high reward research. www.utsouthwestern.edu/newsroom/art...

Musk FRS.

Also needs to be said that (as some folks know) our software packages are named after birds, so while I was away, the lab filled my office with birds... ...but honestly... *very* tastefully. Will stay for the foreseeable future!

I'm hiring for a PhD position at Malmö University, Sweden! The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes. More details and application form: tinyurl.com/4zm92365 Please feel free to share! @vetenskapsradet.bsky.social | @mau.se

Last week, Washington University made the perhaps questionable decision to award me tenure.

Join us for the first inaugural WALII Virtual Symposium on Tuesday, Nov 18, 2025! Abstract submissions for a contributed talk are NOW OPEN! Selected speakers will be chosen in Oct. & will present 10-12 min. talks followed by 3-5 min. of Q&A. Visit: walii.science/virtual-symp...

Reading today’s big NYT Magazine story made me physically sick It details how Trump & the men he put in charge of federal research—men like Jay Bhattacharya & RFK Jr—are dismantling cancer research Not just the US vaccine system—they’re crushing cancer R&D 🎁Link www.nytimes.com/2025/09/14/m...

1/14 Happy (but mostly relieved) to share my dream project with @boudkerlab.bsky.social, now published in @natsmb.nature.com! We used evolution, protein engineering & cryoEM to uncover how ion coupling in glutamate transporters works, and how it evolved.🧵 Free article: go.nature.com/4oRUC1q

Excited to welcome Rohit Pappu (@rohitpappu68.bsky.social) and Meredith Jackrel this week! Be sure not to miss their talks! Sign up here if you've not signed up already! idpseminars.com

Are you a computational biologist who loves the outdoors & is thinking about faculty positions? Then check this out: eeik.fa.us2.oraclecloud.com/hcmUI/Candid... Tenure track position at the University of Wyoming - amazing colleagues, beautiful landscape, and fantastic work-life balance.

🚨🚨IDPSeminars is BACK 🚨🚨 Season 19 (!) gets underway next week with @rohitpappu68.bsky.social and Meredith Jackrel! Date: Thur. Sept 4th Time: 1 pm EST [USA] / 7 pm CET [Europe] If you've previously signed up, you should be good to go, otherwise, please sign up at idpseminars.com

Our 4th generation protocol book has arrived!!

...as we cross the grim milestone of adding supplementary fig. S50, I am beginning to wonder where it all went wrong 🫠

PhD position on studying intrinsically disordered proteins by NMR and single molecule FRET, Dr. Sigrid Milles, The Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de Berlin, Germany leibniz-fmp.softgarden.io/job/58144047... #NMRjobs #NMRchat #NMR 🧲

Although the situation in the world right now is Not Good™, it remains such a preposterous privilege to work with such a wonderful bunch of people. Lab happy hour 25/08/01.

Ebola virus VP35 NNLNS motif modulates viral RNA synthesis and MIB2-mediated signaling https://www.biorxiv.org/content/10.1101/2025.07.27.667045v1

Our SUF4 condensation paper is finally out! cell.com/cell-reports... Thank you to everyone who has scientifically, mentally, and emotionally supported my co-authors and me over the years. Below is a summary of the work-- we hope you enjoy our findings!

Very happy (and frankly relieved) to see this paper finally out in peer-reviewed form. (Preprint was posted in August 2021, but this is the world we live in now). rdcu.be/erMk6

EPIGENETIC HULK READY TO SMASH AGAIN! GET IN LOSERS!

"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT. I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up." Thank you to Dr. Jenna Norton and NIH scientists for your courage!

Starts in 1.5 hours!!

IDPSeminars is back with another seminar this week from @sarahshammas.bsky.social and @sonia-longhi.bsky.social! Come hear about transcriptional regulation and viral pathogenesis! Thursday June 5th! PST 10 am EST 1 pm CET 7 pm! Info: idpseminars.com Signup form: forms.gle/3yCHeYvuuqLh...

If a foreign government conspired to decimate US science and technology in a manner akin to what Project 2025 architects purport to do, we would go to war. Just because they are under a cloak of self declared patriotism does not mean that they are not effectively acting as enemies of the state.

Now published! Big congrats to first author @gginell.bsky.social We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions. www.science.org/doi/10.1126/...

TIL: When the Original Star Wars Trilogy finally aired on Chilean TV in 2003, the network spliced custom beer commercials into the films themselves to avoid cutting to commercial breaks. these additional scenes turn Obi-Wan & Luke into raging space alcoholics who are constantly shotgunning booze.

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

I'd like to share a little bit of happy lab news in these chaotic times: a new preprint, driven by the brilliant Qinhao Cao! www.biorxiv.org/content/10.1... We address a big challenge in synbio: If you give me a protein "X", how can I give you a version of X whose activity is controlled by a kinase?

Back again TOMORROW (Thursday April 3rd) for another IDPSeminars! Noon central time - sign up for the webinar here forms.gle/3yCHeYvuuqLh...

Our 28-yr U-RISE/MARC NIH grant that has served over 500 students and made us one of the top institutions producing African American students who go on to receive MD/PhDs in the United States was just cancelled yesterday. What a unnecessary and tragic end to such an impactful program...

Happening TOMORROW! Get psyched!

The published version of our transcription factor isoforms survey is online www.sciencedirect.com/science/arti... we cloned 100's of isoforms (that arise through alternative splicing etc.) testing them in high-throughput assays for DNA-binding, protein-binding, activation, and more.

I'm so happy to report that our preprint on light-induced collective cell migration has now been published in Cell Systems! This project was a lot of fun and will be the basis for a lot of our ongoing & future work.

An open #PhD position is available in my lab in Munich 🇩🇪 If you are interested in structural biology, #AlphaFold, or disordered proteins, see below for more details. jobs.helmholtz-muenchen.de/jobposting/b... #science #PhD #research

Bluetorial: Women, courage, and leadership What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.

New Preprint ‼️ Work led by the incredible @ananyac2000.bsky.social 💃🏽💃🏽 Mpipi-T is finally here!!! 🥳🥳 👇🏽👇🏽 www.biorxiv.org/content/10.1...

STARTS IN 30 MINUTES!

Now published in JCIM! Thanks to reviewers and our editor for pushing us to (hopefully) clarify a few things and ensure it's clear what PENGUIN is trying to do (and what it's NOT trying to do). Also, in case you were unsure, graphic design is our passion. pubs.acs.org/doi/full/10....

IDPSeminars is back this week (Tomorrow, March 6th)! Come hear about nucleolar organization and IDRs in host-pathogen interactions! PST 10 am EST 1 pm CET 7 pm! Info: idpseminars.com Signup form: forms.gle/3yCHeYvuuqLh...

In lab’s #FIRSTPREPRINT, we present methods to measure nanometer-scale organization around & between specific proteins in condensates in live cells. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.

📣 Want to DONATE to help us Stand Up for Science on March 7th? *NEW LINK!* Make a tax-deductible donation using the QR code below! Direct link: www.paypal.com/ncp/payment/... #scienceforall #sciencenotsilence #standupforscience2025

This is shocking and incredibly sad. Per was a kind and thoughtful scholar and we exchanged many emails over the years on our mutual interest in the constraints IDR interactions place on their evolution. Thoughts and wishes with his family and friends.

And @bornanovak.bsky.social has only gone and won the BPS Student Research Achievement Award in the IDP section for his STARLING work (along with Vicky Liu of the Pappu lab - WashU represent!!)

The STARLING has landed - excited to share new work from @bornanovak.bsky.social and @jefflotthammer.bsky.social in what is also Borna's first Bluesky post! If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).

The answer is yes! Come hear about STARLING this afternoon at the Biophysical Society IDP subgroup symposium! Thread to follow later today... www.biorxiv.org/content/10.1...

Heading out to LA for the 2025 biophysical society meeting! The big question: Can we submit the preprint and get it online before my talk tomorrow?!?! WHO KNOWS!?