Gave my last lecture yesterday. Started celebrating that, for the first time, I managed an entire semester without getting sick. Started feeling sick today 🤒…had a solid run though 😅

On the cover of #SoftMatter! Our work on condensate microstructure. Cover designed by Daniel Tan☺️ pubs.rsc.org/en/content/a...

Have not fully stopped but definitely way less now than before 💔

Very insightful reconsideration what Stress Granules might actually be good for! Going back to the fundamentals & questions arising from Susan Lindquist's and Nancy Kedersha's work. Amazing talk & scholarship by @drummondlab.bsky.social! youtu.be/caAPToh8v0Q

Is there a way to directly connect microstructural dynamics of condensates to their mechanical response? In his new pre-print, Pablo presents a “condensate Deborah number” that does just that! www.biorxiv.org/content/10.1...

Out now in #ACSMacroLett: we demonstrate how molecular charge asymmetry can control the size of condensates! Work done in collaboration with @zwickergroup.bsky.social!! Theory led by Chengjie Luo and simulations by @nathanieldhess.bsky.social!! pubs.acs.org/doi/10.1021/...

Out now in #SoftMatter, our work on linking single molecule features, microstructure, and macroscopic properties of condensates! Led by Daniel Tan, a former undergrad student who is now pursuing a PhD in Computational biophysics, Dilimulati Aierken and Pablo Garcia! pubs.rsc.org/en/content/a...

Now out in #ProteinScience! Work led by the talented 🥳🥳@ananyac2000.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

Who else gets nervous for the first lecture of the semester? It doesn’t matter how many times you’ve taught the course?!!! 😩#fallsemester

On the cover of JACS Au! @alinaemelianova.bsky.social’s work with Pablo and Daniel on using atomistic and residue-resolution coarse-grained simulation to probe interactions between small molecules and biomolecular condensates!! Cover designed by D. Aierken w/ Alina! 1/

I second that!!! ♥️

Huge congratulations to @alinaemelianova.bsky.social Pablo and Daniel on their paper on small-molecule partitioning into condensates now published in JACS Au and selected as ACS Editor’s Choice!!! pubs.acs.org/doi/full/10....

Can't say enough about the Condensates program at @kitp-ucsb.bsky.social. Invigorating discussions, fantastic facilities, and a beautiful location (a place I consider "home"). Thanks to @weber-lab.bsky.social, @jerelleaj.bsky.social, @zwickergroup.bsky.social, and Frank Julicher for organizing!

Few more days left to nominate a rising star in bioengineering! Self-nominations are welcomed!

“Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” The conference associated with our #KITP program on condensates runs for the next three days. Looking forward to meeting everyone and the discussions! www.kitp.ucsb.edu/activities/b...

There’s nothing quite like #KITP! So grateful that we got the opportunity to put this on! The fun continues…🥰

This was a big week for the group! Our four seniors graduated and made us very proud. Ethan graduates as a Sachs Scholar, Ian secured several minors, Daniel won the MacCracken Senior Thesis Award from SEAS, and Caroline earned the highest awards in both CBE and Engineering!

@natsmb.nature.com has launched new content this month, namely Q&As. This interview with Dr. Joseph @jerelleaj.bsky.social‬ www.nature.com/articles/s41... highlights what's great about these pieces. Get to learn about the scientist and their interesting work (consensates/computational biol)!

See u all in Santa Barbara!!

Thanks to @natsmb.nature.com for interviewing on our work: “seeing biomolecular condensates with computation” www.nature.com/articles/s41...

Yesterday was a great day to be at WashU!

Join our interdisciplinary team developing computational approaches to understand and engineer biomolecular condensates. We’re looking for a postdoc—please apply or share with interested persons! 👩🏽‍💻💧🧬 puwebp.princeton.edu/AcadHire/app...

Congratulations to our 4 seniors (Dan, Ethan, Caroline and Ian) on defending their theses today in the #CBE poster session!! We’re so proud! They’re heading off to Rockefeller, Caltech, Fancy Industry job, and UCLA in the fall! 3/4 were the first 3 juniors in the group. *Cue the tears*😭😭

📣 Calling all Rising Stars in Biological Engineering. Nominate someone or self nominate: forms.gle/EszC1AvRFpfN...

Had the best time at Duke over the last three days! Many many thanks to @gladfelterlab.bsky.social and the entire Center for Quantitative Living Systems for being such amazing hosts!

The “social” network inside condensates is quite cliquey 🙃🙃 co-lead by undergrad student Daniel Tan w/ postdoc Dilimulati 🥳🥳🥳 Preprint out!! www.biorxiv.org/content/10.1...

Going to Cali and back to the east coast twice in one week is an extreme sport! #aps #acs #itsawrap

What a week!

This summer in beautiful Santa Barbara we will run a 3-day conference on “Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” June 16 to 18th. Register now: www.kitp.ucsb.edu/activities/b...

Predicting small molecule partitioning into biomolecular condensates is key for designing drugs that target aberrant condensates. But what drives partitioning at the molecular level? (1/6) 🧵👇

Second new preprint ‼️ Work led by brilliant postdoc @alinaemelianova.bsky.social (in collab with Pablo Garcia and Daniel Tan) where we leverage multiscale simulations to predict small-molecule partitioning into condensates 💦💊🙌🏽 www.biorxiv.org/content/10.1...

New Preprint ‼️ Work led by the incredible @ananyac2000.bsky.social 💃🏽💃🏽 Mpipi-T is finally here!!! 🥳🥳 👇🏽👇🏽 www.biorxiv.org/content/10.1...

New pre- print alert‼️ Fantastic work led by Gable Wadsworth (experiments) and Dilimulati Aierken (simulation)! Excited to probe molecular grammars of nucleic acid LCST behaviors in collaboration with @priya-r-banerjee.bsky.social 🥳🥳

Huge congrats to Ethan from our group on being named a Sachs Scholar!!! 🥳🥳🥳 www.princeton.edu/news/2025/02...

Congratulations to Daniel Tan from our group for winning the #BPS Poster Award Competition!! 🥳🥳🥳 What an achievement!!! Cheers to all the other winners!!

Proud to have the final version of our paper on mutations + condensates + scaling laws published in @elife.bsky.social! Work led by @juliamaristany.bsky.social w/ @rcollepardo.bsky.social ! Read the digest here: elifesciences.org/digests/9906...

Sad to miss #BPS this year. Luckily two members of the group are representing and so proud of them!! First up, star postdoc Dilimulati Aierken will co-chair the condensate session on Sunday and present his work on RNA interactions + condensates 🥰🥰🥰

Now online - the Review "Structured protein domains enter the spotlight: modulators of #biomolecularcondensate form and function" from Nathaniel Hess and @jerelleaj.bsky.social. #PhaseSeparation #ProteinProteinInteraction #Oligomerization #ProteinRNAInteraction authors.elsevier.com/sd/article/S...

It's about time we have a conversation about the role of structured protein domains in form and function of bimolecular condensates. Proud of graduate student Nate Hess for taking the lead on synthesizing these ideas and identifying important gaps in the field!! www.sciencedirect.com/science/arti...

The application window for the Summer Undergraduate Research Program in Computational Physical Chemistry at NYU is now open. This is a a 10-week summer program with a stipend of $10,000. Open to all U.S. students who are not already at NYU. Details at wp.nyu.edu/sccpc/summer...

“Biomolecular condensates control and are defined by RNA–RNA interactions that arise in viral replication”. New results from a wonderful collaboration with @gladfelterlab.bsky.social and Christine Roden (who just started her lab at University of Montreal!!) www.biorxiv.org/content/10.1...

Joseph Group Holiday Party 2024!! 🥳🥳

End of year festivities with the senior members of the group! 🥳🥳🥳 feel so lucky to get to work with them! ♥️🥺

Gave my last lecture for 2024 today ☺️ …from stat mech to MC to MD and then QM! Happy to say that I completed most of the syllabus 😅😅