Thrilled to contribute to this fantastic collaboration with @georg-meisl.bsky.social, @arosiolabeth.bsky.social, @tscheidt.bsky.social (many others). Lots of great experimental work went into this paper, but here's a brief thread on what I find exciting from the theory side. doi.org/10.1038/s414...

Structural defects in amyloid-β fibrils drive secondary nucleation www.nature.com/articles/s41...

Multidisciplinary training, over time, produces the highest impact people www.science.org/doi/10.1126/...

Physicist Leo Szilard, in a short science fiction story from 1948, describing how to retard science by making the funding application longer and harder than the proposed research - now called the ‘Szilard point’

Excited to share the first paper from my group with Gianluca Teza (MPI-PKS) and Attilio L. Stella (U Padova)! “Coarse-Graining via Lumping: Exact Calculations and Fundamental Limitations” shows when lumping is exact and when it fails even without approximations. arxiv.org/pdf/2512.11974

Finally!

Very cool work. I also thought about Hwa's growth laws while reading the thread. Quantitative curves are great to stimulate chin scratching!

Here’s the thing, emerging scientists aren’t going to flee to do science elsewhere…they just won’t do the science. We will lose at least one, if not two generations of knowledge if we don’t get this shit sorted out immediately.

The US is funding fewer grants compared to the past. The money is given in one lump sum instead a yearly infusion from a multi-year funded grant. This leads to more competition, less $ and time to do research. Not a win-win situation. 🧪🎁🔗 www.nytimes.com/interactive/...

"I, at any rate, am convinced that He is not playing at dice." Einstein sent a letter to Max Born #OTD in 1926, in which he gave his oft-quoted objection to the probabilistic interpretation of the wavefunction in quantum mechanics. 🧪 ⚛️ You may be surprised by where this is headed. (1/n)

We're back for our final seminar of 2025 with talks from @alexholehouse.bsky.social and Birthe Kragelund! 1 pm EST or 7 pm European time. If you're not already signed up, head on over to idpseminars.com to register!

New publication! How to read the curves in biomolecular phase diagrams! A collaboration between the Schmit Group and Jonathon Ditlev, Les Loew, and @ani-chattaraj.bsky.social. 1/7 pubs.acs.org/doi/10.1021/...

Out now in #SoftMatter, our work on linking single molecule features, microstructure, and macroscopic properties of condensates! Led by Daniel Tan, a former undergrad student who is now pursuing a PhD in Computational biophysics, Dilimulati Aierken and Pablo Garcia! pubs.rsc.org/en/content/a...

Excited to share our paper: “Historical and Experimental Evidence that Inherent Properties Are Overweighted in Early Scientific Explanation” I’m grateful to Zach Horne & my dear advisor @andreicimpian.bsky.social to let me be part of this project, it was a great experience! doi.org/10.1073/pnas...

Biomolecular phase boundaries are described by a solubility product that accounts for variable stoichiometry and soluble oligomers https://www.biorxiv.org/content/10.1101/2025.08.27.672390v1

"What does this curved line mean?" Like palm reading for your phase boundary. Plus, when is your condensate actually an oligomer (or vice versa)? A new preprint from the Schmit Group, in collaboration with Jonathon Ditlev, Les Loew, and @ani-chattaraj.bsky.social www.biorxiv.org/content/10.1...

Can't say enough about the Condensates program at @kitp-ucsb.bsky.social. Invigorating discussions, fantastic facilities, and a beautiful location (a place I consider "home"). Thanks to @weber-lab.bsky.social, @jerelleaj.bsky.social, @zwickergroup.bsky.social, and Frank Julicher for organizing!

What nanometer structure-function relationships exist in your favorite condensate? We hope you will try to measure it! Congrats to Kris, @evdokiiap.bsky.social, Abby, Archish, Gandhar, and @schmitbiophysics.bsky.social . 4/4

In lab’s #FIRSTPREPRINT, we present methods to measure nanometer-scale organization around & between specific proteins in condensates in live cells. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.

Here is a thread on a paper we published on Dec 30th: doi.org/10.1038/s414... In this collaborative work, we looked at the structure of proteins behind Huntington’s disease. HD is an inherited neurodegenerative disease, with patients having a mutated form of the huntingtin gene. (1/..)

Hoping the demise of the clock app drives me to discover more cool science here.

When the turkey is supposed to be the centerpiece but your 12yo steals your thunder.

Cutting NIH funding to improve federal cash flow is like cutting the wings off an airplane to make it lighter.

Shopping for summer 2025 conferences. Pitch me your favorites in: Biological LLPS Amyloids Self-assembly Soft condensed matter Physics Chromatin Systems biology Other???

Excited to find this place and find all the people from the biophysics and LLPS community are already here! I'd like to link up with the soft condensed matter community too. Any suggestions?