bioRxiv Biophysics
@biorxiv-biophys.bsky.social
📤 3155
📥 0
📝 4869
Integrating NMR restraints into coarse-grained simulations: toward accurate conformational ensembles of complex protein systems
https://www.biorxiv.org/content/10.64898/2025.12.22.695971v1
about 1 hour ago
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Spatio-temporal resource landscapes govern the confinement and escape of therapy-resistant mutants in structured populations
https://www.biorxiv.org/content/10.64898/2025.12.22.695823v1
about 1 hour ago
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Enhancing the imaging rate of high-speed atomic force microscopy using a combination of multiple techniques
https://www.biorxiv.org/content/10.64898/2025.12.22.695957v1
about 2 hours ago
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Mechanistic Interpretability of Fine-Tuned Protein Language Models for Nanobody Thermostability Prediction
https://www.biorxiv.org/content/10.64898/2025.12.22.695878v1
about 5 hours ago
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Evidence for the Progressive Improvement of All-Atom Force Fields in Reproducing Local Conformational Preferences of Flexible Peptides
https://www.biorxiv.org/content/10.64898/2025.12.22.695171v1
about 10 hours ago
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2
1
A food chain of ribozymes built on an ancestral strand
https://www.biorxiv.org/content/10.64898/2025.12.22.695801v1
about 17 hours ago
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2
1
The Structural Basis for RNA Binding and Recognition of the Disordered Prion-Like Domain of TDP-43
https://www.biorxiv.org/content/10.64898/2025.12.22.695782v1
about 17 hours ago
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1
1
Molecular interactions underlying selective partitioning of clients into MED1 and FUS condensates
https://www.biorxiv.org/content/10.64898/2025.12.23.696191v1
about 17 hours ago
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1
1
Dynamic domain interactions encode possible CheA autophosphorylation mechanisms revealed by coarse-grained simulations
https://www.biorxiv.org/content/10.64898/2025.12.21.695815v1
about 21 hours ago
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Quantum Computing Reveals Energetics of Tau Peptide Fragments
https://www.biorxiv.org/content/10.64898/2025.12.21.695828v1
about 21 hours ago
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Backbone Hydrogen Bonding as a Determinant of Condensate Material States
https://www.biorxiv.org/content/10.64898/2025.12.21.695814v1
about 22 hours ago
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Characterizing the Impact of Nucleoid-Associated Proteins on HU-DNA Interactions by Live-Cell Single-Molecule Tracking
https://www.biorxiv.org/content/10.64898/2025.12.19.695591v1
1 day ago
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Drude SILCS-Nucleic: Harnessing Explicit Electronic Polarization in Targeting RNA and DNA for Drug Design
https://www.biorxiv.org/content/10.64898/2025.12.20.695737v1
1 day ago
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3
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Fingerprints as Frozen Nematic Fields
https://www.biorxiv.org/content/10.64898/2025.12.19.695577v1
1 day ago
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3
1
The spatial and temporal spread of highly pathogenic avian influenza in North America: Newton's Cradle hypothesis
https://www.biorxiv.org/content/10.64898/2025.12.19.695483v1
2 days ago
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Fractionation-Free Protein Corona Quantification Through Synchrotron-Based Small-Angle X-ray Scattering
https://www.biorxiv.org/content/10.64898/2025.12.19.695217v1
2 days ago
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Contactless micro-elastography of single cells using oscillating microbubbles as shear wave sources
https://www.biorxiv.org/content/10.64898/2025.12.19.695456v1
2 days ago
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Myelin Basic Protein Binding Is Modulated by Leaflet Asymmetry and Lipid Composition
https://www.biorxiv.org/content/10.64898/2025.12.19.695364v1
2 days ago
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2
1
Multiscale modeling of blood circulation with cerebral autoregulation and network pathway analysis for hemodynamic redistribution in the vascular network with anatomical variations and stenosis conditions
https://www.biorxiv.org/content/10.64898/2025.12.19.695348v1
2 days ago
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Robust ciliary flows protect early Xenopus embryos from pathogens independent of multiciliated cell patterning
https://www.biorxiv.org/content/10.64898/2025.12.19.694354v1
2 days ago
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2
1
Structural basis of half-site reactivity in Class Ib ribonucleotide reductases
https://www.biorxiv.org/content/10.64898/2025.12.21.695763v1
3 days ago
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PIP2 Binding at Allosteric Site Blocks Activation in Human Rod CNG Channels
https://www.biorxiv.org/content/10.64898/2025.12.19.695557v1
3 days ago
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1
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Kalman-filter Force Inference: an estimation framework for cellular forces from temporal evolution of epithelial morphogenesis
https://www.biorxiv.org/content/10.64898/2025.12.19.695339v1
3 days ago
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A geometric-surface PDE model for cell-nucleus translocation through confinement
https://www.biorxiv.org/content/10.64898/2025.12.18.695144v1
4 days ago
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1
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Tuning the H2 Production Activity of ToHydA by Molecular Simulation-Informed Protein Engineering
https://www.biorxiv.org/content/10.64898/2025.12.18.695218v1
4 days ago
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Molecular basis for thermoresponsive protein condensation in plants
https://www.biorxiv.org/content/10.64898/2025.12.18.695255v1
4 days ago
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The structural disorder of Dsup and its interaction with the human nucleosome: A computational study
https://www.biorxiv.org/content/10.64898/2025.12.17.694834v1
5 days ago
0
1
1
Drop on fixed target reaction initiation approach for serial and time resolved crystallography
https://www.biorxiv.org/content/10.64898/2025.12.17.694847v1
5 days ago
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1
1
Explainable Active Learning Framework for Ligand BindingAffinity Prediction
https://www.biorxiv.org/content/10.64898/2025.12.17.694851v1
5 days ago
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Self-blinking dye restores efficient use of nanobodies in single-molecule localization microscopy.
https://www.biorxiv.org/content/10.64898/2025.12.17.694880v1
5 days ago
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Learning Epithelial Elasticity via Local Tension Remodeling
https://www.biorxiv.org/content/10.64898/2025.12.17.694921v1
5 days ago
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Structural Basis of TACO1-Mediated Efficient Mitochondrial Translation
https://www.biorxiv.org/content/10.64898/2025.12.18.695269v1
5 days ago
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Wrinkles emerge from matrix complementarity in heterogenous biofilms
https://www.biorxiv.org/content/10.64898/2025.12.18.695073v1
5 days ago
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Single-Particle Tracking and Positional Phenotyping Reveals Variant-Specific Early Checkpoints in SARS-CoV-2 Cell Entry
https://www.biorxiv.org/content/10.64898/2025.12.18.695048v1
5 days ago
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In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
https://www.biorxiv.org/content/10.64898/2025.12.18.694444v1
5 days ago
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1
1
Tunable multivalent Fe(II)-based glycoassemblies as mimetics for native high-mannose glycans.
https://www.biorxiv.org/content/10.64898/2025.12.17.694979v1
5 days ago
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Differential receptor activation defines the fundamental limit of chemotactic sensing
https://www.biorxiv.org/content/10.64898/2025.12.17.694457v1
5 days ago
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1
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Boxcar Imaging FCS Reveals Membrane Raft Stabilization Kinetics in Antigen-Stimulated Mast Cells
https://www.biorxiv.org/content/10.64898/2025.12.16.694662v1
6 days ago
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Spatiotemporal mapping of microscale stiffness during collagen polymerization and crosslinking by optical multifrequency time-harmonic elastography
https://www.biorxiv.org/content/10.64898/2025.12.16.694603v1
6 days ago
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1
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Capsid flexibility during Ty1 virus-like particle assembly
https://www.biorxiv.org/content/10.64898/2025.12.17.694965v1
6 days ago
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Enhanced sampling of protein conformations in AlphaFold3 with repulsive bias in the diffusion generative model
https://www.biorxiv.org/content/10.64898/2025.12.17.693105v1
6 days ago
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1
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Single-molecule tracking of RNA-DNA hybrid removal enzymes important for lagging-strand replication
https://www.biorxiv.org/content/10.64898/2025.12.17.694926v1
6 days ago
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1
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Single-molecule FRET with a minimalistic 3D-printed setup and dyes in the blue-green spectral region
https://www.biorxiv.org/content/10.64898/2025.12.16.694555v1
6 days ago
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1
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Synaptic active zones are ordered nanostructures designed by supramolecular block copolymers
https://www.biorxiv.org/content/10.64898/2025.12.15.691964v1
6 days ago
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Substrates Coupling and Inhibition of the human Na+- dependent Cl-/HCO3-exchanger
https://www.biorxiv.org/content/10.64898/2025.12.15.693380v1
7 days ago
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Lipidomic Profile Reconstruction of TherapeuticMembrane Targets Using Physics-BasedOptimization with Limited Activity Data
https://www.biorxiv.org/content/10.64898/2025.12.15.694365v1
7 days ago
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Control of cellular cortical tension and shape by RhoGTPase signalling
https://www.biorxiv.org/content/10.64898/2025.12.15.694413v1
7 days ago
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Machine learning-based development of Gadolinium binding peptides
https://www.biorxiv.org/content/10.64898/2025.12.14.694215v1
7 days ago
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Excitable dynamics of ParA during bacterial cell division
https://www.biorxiv.org/content/10.64898/2025.12.16.694648v1
8 days ago
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Confinement prevents postmenopausal osteoporosis and obesity via nuclear mechanical remodeling
https://www.biorxiv.org/content/10.64898/2025.12.15.693823v1
8 days ago
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