bioRxiv Biophysics
@biorxiv-biophys.bsky.social
📤 3124
📥 0
📝 4566
When Animals Turn Inside Out: The Eversion of Bloodworms
https://www.biorxiv.org/content/10.1101/2025.11.05.686822v1
about 14 hours ago
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Massively parallel evolution reveals a biophysical scaling law between cell size and internal cell density
https://www.biorxiv.org/content/10.1101/2025.11.05.686806v1
about 16 hours ago
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A hydrophobic cluster controls long-range allostery in the TRMT2A RNA recognition motif
https://www.biorxiv.org/content/10.1101/2025.11.05.686750v1
about 20 hours ago
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Hepatitis B virus HBx protein masks epigenetic reader Spindlin1 via an inter-molecular zinc finger to subvert transcriptional control
https://www.biorxiv.org/content/10.1101/2025.11.05.686744v1
about 20 hours ago
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Direct Optical Quantification of Chain Collapse, Reduced Dielectric, and Water Release Driving Protein Phase Separation
https://www.biorxiv.org/content/10.1101/2025.11.04.686660v1
about 21 hours ago
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Identification of a First-In-Class Small Molecule CAPON Binder Using Affinity Selection-Mass Spectrometry Screening
https://www.biorxiv.org/content/10.1101/2025.11.05.686689v1
about 21 hours ago
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Molecular Dynamics-Guided All-Atom Reconstruction of Cryo-ET Maps Reveals Mechanisms of Histone Tail-Mediated Chromatin Compaction
https://www.biorxiv.org/content/10.1101/2025.11.05.686627v1
1 day ago
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Temporal Dynamics of Antigen-Specific T Cell Expansion in Primary SARS-CoV-2 Infection
https://www.biorxiv.org/content/10.1101/2025.11.04.686558v1
1 day ago
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An agent-based model of Trypanosoma brucei social motility to explore determinants of colony pattern formation
https://www.biorxiv.org/content/10.1101/2025.11.04.686461v1
2 days ago
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Key determinants of VDAC-hexokinase I complex assembly revealed by a minimal vesicle-based interaction assay
https://www.biorxiv.org/content/10.1101/2025.11.03.686449v1
3 days ago
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Rule-based mitigation of charge asymmetry-triggered monoclonal antibody self-assembly
https://www.biorxiv.org/content/10.1101/2025.11.03.686261v1
3 days ago
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qcGEM: a graph-based molecular representation with quantum chemistry awareness
https://www.biorxiv.org/content/10.1101/2025.11.02.686183v1
3 days ago
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Geometry-Constrained Prediction of Catalytically Competent Kinase Domains Across the Human Kinome
https://www.biorxiv.org/content/10.1101/2025.11.03.686188v1
3 days ago
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Blind Prediction of Complex Water and Ion Ensembles Around RNA in CASP16
https://www.biorxiv.org/content/10.1101/2025.11.03.685595v1
4 days ago
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Transforming a Fragile Protein Helix into an Ultrastable Scaffold via a Hierarchical AI and Chemistry Framework
https://www.biorxiv.org/content/10.1101/2025.11.03.686355v1
4 days ago
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Neutral Frustration Landscape Architecture of SARS-CoV-2 Spike -Antibody Interfaces Shapes Immune Evasion Mechanisms for Ultrapotent ...
https://www.biorxiv.org/content/10.1101/2025.10.31.685956v1
4 days ago
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Aducanumab Binding to Aβ1-42 Fibrils Alters Dynamics of the N-Terminal Tail While Preserving the Fibril Core
https://www.biorxiv.org/content/10.1101/2025.11.01.686027v1
4 days ago
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Probing the energy landscape of α-Synuclein amyloid fibril formation by systematic K-to-Q mutagenesis
https://www.biorxiv.org/content/10.1101/2025.11.01.685997v1
4 days ago
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Dangling Ends of Third Strand and Duplex Drive Nucleic Acid Triplex Stabilization through Bimodal Association
https://www.biorxiv.org/content/10.1101/2025.11.02.686076v1
4 days ago
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SIMAIS: A swarm intelligence inspired biosensor for rapid protein detection
https://www.biorxiv.org/content/10.1101/2025.10.31.685929v1
4 days ago
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T cell costimulatory and inhibitory signals differentially modulate LAT condensate nucleation propensity after TCR ligation
https://www.biorxiv.org/content/10.1101/2025.11.01.685673v1
4 days ago
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A Python framework for magnetic tweezers real-time image processing and microscope control
https://www.biorxiv.org/content/10.1101/2025.10.31.685671v1
4 days ago
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Mapping Allosteric Rewiring in Viral RNA: Sequence-Encoded Control of Protein Binding Mechanisms
https://www.biorxiv.org/content/10.1101/2025.11.01.685830v1
5 days ago
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Structural basis for lipid binding by the blood protein vitronectin, a component of HDL
https://www.biorxiv.org/content/10.1101/2025.11.01.685992v1
5 days ago
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Studying macromolecular composition in cell-cell interfaces using 3D membrane reconstitution systems
https://www.biorxiv.org/content/10.1101/2025.11.01.686034v1
5 days ago
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Physical mechanisms of nanoparticle-membrane interactions: A coarse-grained study
https://www.biorxiv.org/content/10.1101/2025.10.31.685850v1
5 days ago
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CryoWriter: A Robotic Solution for Improved Cryo-EM Grid Preparation
https://www.biorxiv.org/content/10.1101/2025.11.01.686008v1
5 days ago
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Classification models distinguish functional and trafficking effects of KCNQ1 variants to enhance variant interpretation
https://www.biorxiv.org/content/10.1101/2025.10.31.685955v1
5 days ago
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Structural Mechanism of Prestin-Membrane Mechanotransduction
https://www.biorxiv.org/content/10.1101/2025.10.31.685930v1
6 days ago
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Mathematical modeling of light chain aggregation and cardiac damage in AL amyloidosis
https://www.biorxiv.org/content/10.1101/2025.10.30.685705v1
6 days ago
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A unifying model of LAT condensates in reconstitution experiments
https://www.biorxiv.org/content/10.1101/2025.10.31.685772v1
6 days ago
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The secreted staphylococcal biofilm protein Sbp forms biomolecular condensates in the presence of DNA
https://www.biorxiv.org/content/10.1101/2025.10.30.685619v1
6 days ago
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Protein-protein interaction networks can be highly sensitive to the membrane phase transition
https://www.biorxiv.org/content/10.1101/2025.10.30.685611v1
7 days ago
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Viscoelasticity Analysis of Coarse-grained Cytoskeletal Simulations with Cytosim and Cytocalc
https://www.biorxiv.org/content/10.1101/2025.10.30.685558v1
7 days ago
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Glycation enhances protein association with lipid bilayer membranes
https://www.biorxiv.org/content/10.1101/2025.10.30.685514v1
7 days ago
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Two-dimensional NMR from a Single Pulse: Reconstructing Heteronuclear 2D spectra via off-resonance decoupling and Deep Neural Networks
https://www.biorxiv.org/content/10.1101/2025.10.30.685498v1
7 days ago
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Nuclear Packing Sets Fluidity Along the Epithelial to Mesenchymal Spectrum
https://www.biorxiv.org/content/10.1101/2025.10.29.684532v1
8 days ago
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Dual-Field Interference as a Common Biomechanical Origin of Cell Division, Differentiation, and Aging
https://www.biorxiv.org/content/10.1101/2025.10.28.684574v1
8 days ago
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Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system
https://www.biorxiv.org/content/10.1101/2025.10.29.685381v1
8 days ago
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Structural and Functional Insights into Alkaline-pH Sensing by the Alka Channel
https://www.biorxiv.org/content/10.1101/2025.10.29.685377v1
8 days ago
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Cytokines control the physical state of immune tissue
https://www.biorxiv.org/content/10.1101/2025.10.28.685215v1
8 days ago
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Mechanical de-skewing enables high-resolution imaging of thin tissue slices with a mesoSPIM light-sheet microscope
https://www.biorxiv.org/content/10.1101/2025.10.29.684106v1
8 days ago
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Electric field intensity modulates keratocyte migration without altering turning dynamics
https://www.biorxiv.org/content/10.1101/2025.10.29.684651v1
8 days ago
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Two-Step Mechanism of Bruton's Tyrosine Kinase MembraneRecruitment and Activation
https://www.biorxiv.org/content/10.1101/2025.10.28.685231v1
8 days ago
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Uniform distribution of photosystems in dark-adapted Synechocystis cells
https://www.biorxiv.org/content/10.1101/2025.10.29.685299v1
8 days ago
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Quantitative comparison of methodologies for translation site imaging in living cells
https://www.biorxiv.org/content/10.1101/2025.10.29.685314v1
8 days ago
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Coupling Step-Wise Motility and Traction Force Patterns in chemotaxing cells
https://www.biorxiv.org/content/10.1101/2025.10.28.685178v1
8 days ago
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The dynamic response of the bacterial flagellar motor to its direct intracellular input signal
https://www.biorxiv.org/content/10.1101/2025.10.28.684865v1
8 days ago
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A conformationally heterogeneous bending pivot enables bent-to-straight transition in the central helix of mycobacterial FtsZ
https://www.biorxiv.org/content/10.1101/2025.10.28.685025v1
9 days ago
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Prioritizing Stability-enhancing Mutations using a Protein Language Model in conjunction with Physics-Based Predictions
https://www.biorxiv.org/content/10.1101/2025.10.28.683791v1
9 days ago
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