Analysis and design of disordered polypeptides with optimized sequence patterning properties https://www.biorxiv.org/content/10.64898/2026.02.20.707115v1

An ER retention motif controls the heteromeric stoichiometry of hERG1a/1b channels https://www.biorxiv.org/content/10.64898/2026.02.20.707017v1

Mathematical Modeling of AA Amyloidosis: Coupling SAA-HDL Binding Dynamics with Path-Dependent Renal Aging https://www.biorxiv.org/content/10.64898/2026.02.19.706923v1

Fusion of lipid membranes: an alternative pathway https://www.biorxiv.org/content/10.64898/2026.02.19.706911v1

Magnetic sensitivity of cryptochrome 4a in domesticated quail with migratory origins https://www.biorxiv.org/content/10.64898/2026.02.19.706734v1

Subdomains of Endophilin-NBAR Can Synergistically Drive Membrane Remodeling and Facilitate Controlled Membrane Scission https://www.biorxiv.org/content/10.64898/2026.02.19.706845v1

Heterogeneity in cilia patterning enables multiple flow functions within a single cell https://www.biorxiv.org/content/10.64898/2026.02.19.706812v1

Actomyosin active torques determine body plan handedness in C. elegans https://www.biorxiv.org/content/10.64898/2026.02.19.706789v1

QuantiTrack: A unified software to study protein dynamics in living cells https://www.biorxiv.org/content/10.64898/2026.02.19.706877v1

Diurnal regulation of flagellar length and swimming speed in the red-tide raphidophyte Chattonella marina https://www.biorxiv.org/content/10.64898/2026.02.18.706705v1

A rapid, low-cost approach to solid immersion lens fabrication for enhanced resolution in optical microscopy https://www.biorxiv.org/content/10.64898/2026.02.19.706816v1

Chronotype asymmetry arises from stochastic sleep homeostasis under circadian entrainment https://www.biorxiv.org/content/10.64898/2026.02.18.706715v1

BEEP Learning: Multi-View Image Decomposition for Massively Multiplexed Biological Fluorescence Microscopy https://www.biorxiv.org/content/10.64898/2026.02.19.706833v1

A predictive mechanochemical modeling framework for the deformation and remodeling of the nuclear lamina https://www.biorxiv.org/content/10.64898/2026.02.19.706840v1

Dynamics of single cell-cell junctions as an indicator of cell state switch https://www.biorxiv.org/content/10.64898/2026.02.18.706725v1

Coarse-Grained Simulations of Mycobacterial Outer Membranes Reveal Fluidity-Dependent PDIM Redistribution Across Different Lipid Environments https://www.biorxiv.org/content/10.64898/2026.02.18.706594v1

The biophysical properties of the bacterial nucleoid are dynamic, heterogeneous, and responsive to perturbations of cellular processes https://www.biorxiv.org/content/10.64898/2026.02.18.706702v1

Membrane Environment Sets the Functional pKa of Ionizable Lipids https://www.biorxiv.org/content/10.64898/2026.02.18.706567v1

Asymmetry-induced distinct mechanisms and the transporting role of sodium in bacterial fluoride channel Fluc https://www.biorxiv.org/content/10.64898/2026.02.18.706662v1

The magnetic field-dependent fluorescence of MagLOV2 in live bacterial cells is consistent with the radical pair mechanism https://www.biorxiv.org/content/10.64898/2026.02.18.706690v1

Systematic mutational mapping reveals optimal amyloid formation for RIPK function https://www.biorxiv.org/content/10.64898/2026.02.19.706818v1

A Non-Alchemical Absolute Binding Free Energy Framework for Small Molecule Drugs https://www.biorxiv.org/content/10.64898/2026.02.18.706686v1

Fuel-driven catalytic molecular templating https://www.biorxiv.org/content/10.64898/2026.02.18.706517v1

Cumulative geomagnetic disturbances modulate global photosystem stoichiometry through temperature-dependent gating https://www.biorxiv.org/content/10.64898/2026.02.17.706448v1

Mechanisms of macular oedema development and therapeutic response: An in-silico modelling study https://www.biorxiv.org/content/10.64898/2026.02.17.706117v1

Membrane tubulation by adhesion of spherical nanoparticles https://www.biorxiv.org/content/10.64898/2026.02.17.706332v1

ATLAS: Graph-based 3D RNA Motif Library Incorporating non-Watson-Crick Interactions https://www.biorxiv.org/content/10.64898/2026.02.17.706471v1

Local Confinement within Plasma Membrane Nanodomains Drives Constitutive Activity of GPCRs https://www.biorxiv.org/content/10.64898/2026.02.17.706370v1

Real-time mass-resolved label-free single-molecule immunoassay https://www.biorxiv.org/content/10.64898/2026.02.17.706360v1

Finite Element Modeling of the Scaphoid Shift Maneuver: Implications for Scapholunate Ligament injuries https://www.biorxiv.org/content/10.64898/2026.02.17.705556v1

Mechanism of Gating and Isoform-Specific Inhibition in Renal CLC Chloride Channels https://www.biorxiv.org/content/10.64898/2026.02.17.706469v1

High-Performance, Computer-Controlled Bipedal DNA Motor https://www.biorxiv.org/content/10.64898/2026.02.17.706383v1

Structural Rewiring of IL-7R Dimerization by an Oncogenic Transmembrane Mutation Can Be Reversed by Rational Design https://www.biorxiv.org/content/10.64898/2026.02.17.706319v1

Quantifying interleaflet coupling of phase behavior and observing anti-registered phases in asymmetric lipid bilayers https://www.biorxiv.org/content/10.64898/2026.02.17.706271v1

Engineering nanocondensate formation through sequence composition and patterning https://www.biorxiv.org/content/10.64898/2026.02.17.706365v1

Estimation of Protein Melting Temperatures Using Small-Ladder Replica Exchange Simulations https://www.biorxiv.org/content/10.64898/2026.02.17.706302v1

Chemical interactions in polyethylene glycol-induced condensates lead to an anomalous FRET response from a flexible linker-fluorescent protein crowding sensor https://www.biorxiv.org/content/10.64898/2026.02.16.706251v1

Myosin Filaments of Vertebrate Skeletal and Cardiac Muscle are Highly Similar, but not Identical https://www.biorxiv.org/content/10.64898/2026.02.16.706210v1

A Goldilocks zone of DNA flexibility defines stable yet plastic nucleosomes, tuned by histone chemistry https://www.biorxiv.org/content/10.64898/2026.02.16.706184v1

Bringing calorimetry (back) to life https://www.biorxiv.org/content/10.64898/2026.02.16.706158v1

Cellular Chemical Dynamics Governing Signal Transduction and Adaptive Gene Expression: Beyond Classical Kinetics https://www.biorxiv.org/content/10.64898/2026.02.13.705865v1

Piezo2 tension sensitivity and its modulation by alternative splicing https://www.biorxiv.org/content/10.64898/2026.02.16.706133v1

Quantitative mapping of nanoscale EGFR-Grb2 assemblies by DNA-PAINT https://www.biorxiv.org/content/10.64898/2026.02.16.706070v1

Non-muscle actinopathy-associated loss-of-function actin variants modulate cytoskeletal reorganization https://www.biorxiv.org/content/10.64898/2026.02.13.705838v1

Ion Mobility Mass Spectrometry Guided Modeling with AlphaFold and Rosetta Improves Protein Complex Structure Prediction https://www.biorxiv.org/content/10.64898/2026.02.16.706193v1

Growth-dependent sensory bet-hedging enhances collective navigation https://www.biorxiv.org/content/10.64898/2026.02.13.705748v1

Large-scale exploration of protein space by automated NMR https://www.biorxiv.org/content/10.64898/2026.02.16.706194v1

Bacterial GTPases act as successive placeholders to mediate ribosome assembly and its coupling to translation initiation https://www.biorxiv.org/content/10.64898/2026.02.15.706057v1

Phasor analysis of RGB camera data enables fluorescence microscopy unmixing and brightfield segmentation in a commercial microscope https://www.biorxiv.org/content/10.64898/2026.02.13.705652v1

ATP-driven conformational dynamics reveal hidden intermediates in a heterodimeric ABC transporter https://www.biorxiv.org/content/10.64898/2026.02.12.705656v1