bioRxiv Biophysics
@biorxiv-biophys.bsky.social
📤 3237
📥 0
📝 5559
Rapid and reliable quantification of cytosolic mRNA escape (RNASCAPE)
https://www.biorxiv.org/content/10.64898/2026.04.07.716953v1
about 20 hours ago
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Extending the MARTINI 3 Coarse-Grained Forcefield to Polypeptoids
https://www.biorxiv.org/content/10.64898/2026.04.10.717689v1
about 23 hours ago
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2
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Integrating computational chemistry and machine learning to predict KRAS mutation-induced resistance
https://www.biorxiv.org/content/10.64898/2026.04.10.717640v1
about 23 hours ago
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Structural features of E. coli Stx bacteriophage phi24B revealed with cryo-electron microscopy
https://www.biorxiv.org/content/10.64898/2026.04.10.717836v1
1 day ago
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The Central Coupler of the AAA+ ATPase ClpXP Controls Intersubunit Communication and Couples the Conversion of Chemical Energy into the Generation of Force
https://www.biorxiv.org/content/10.64898/2026.04.10.717754v1
1 day ago
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1
1
Proton tunneling at the ryanodine receptor Ca2+ activation site provides temperature-invariant noise for robust Ca2+-induced Ca2+ release
https://www.biorxiv.org/content/10.64898/2026.04.08.717335v1
2 days ago
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Recovering membrane interaction kinetics of single molecules from 3D tracking data
https://www.biorxiv.org/content/10.64898/2026.04.08.717195v1
2 days ago
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3
1
Molecular basis of protein-glycan cross-linking by CpCBM92A revealed by NMR spectroscopy
https://www.biorxiv.org/content/10.64898/2026.04.08.717144v1
2 days ago
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0
1
Deciphering Coccolith Formation: Advanced Microscopy Insights from the Biomineralisation of Gephyrocapsa huxleyi
https://www.biorxiv.org/content/10.64898/2026.04.08.717164v1
2 days ago
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Spatially patterned, spectral single-molecule microscopy
https://www.biorxiv.org/content/10.64898/2026.04.08.715690v1
2 days ago
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3
2
KinConfBench: A Curated Benchmark for Cofolding Models on Kinase Conformational States
https://www.biorxiv.org/content/10.64898/2026.04.07.716788v1
2 days ago
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Investigating a Relation between Amyloid Beta Plaque Burden and Accumulated Neurotoxicity Caused by Amyloid Beta Oligomers
https://www.biorxiv.org/content/10.64898/2026.04.07.717091v1
2 days ago
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Serial femtosecond crystallography reveals the pH-driven allosteric mechanism of hexamer glargine
https://www.biorxiv.org/content/10.64898/2026.04.07.716775v1
2 days ago
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1
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Uncompromised, multimodal, multiscale structural analysis of the hierarchically organization in mineralized tissues
https://www.biorxiv.org/content/10.64898/2026.04.07.717027v1
2 days ago
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Generation-Establishment Tradeoffs Shape the Temporal Window of Recombinant Evolution
https://www.biorxiv.org/content/10.64898/2026.04.07.717007v1
3 days ago
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Membrane structural properties in Staphylococcus aureus are tuned by the carotenoid 4,4'-diaponeurosporenoic acid
https://www.biorxiv.org/content/10.64898/2026.04.08.716698v1
3 days ago
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Orthosteric and allosteric effects of anti-CRISPR II-C1 inhibition on GeoCas9 from integrated structural biophysics
https://www.biorxiv.org/content/10.64898/2026.04.08.717222v1
3 days ago
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Localized ribosome access and distal tuning via the Listeria prfA RNA thermometer
https://www.biorxiv.org/content/10.64898/2026.04.08.717274v1
3 days ago
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Dimerisation and twist reversal of the Lewy fold in α-synuclein mutants with Parkinson's disease and dementia
https://www.biorxiv.org/content/10.64898/2026.04.07.716933v1
3 days ago
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Simultaneous Denoising and Baseline Correction of Microplate Raman Spectra Using a Dual-Branch U-Net
https://www.biorxiv.org/content/10.64898/2026.04.07.716998v1
3 days ago
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Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins
https://www.biorxiv.org/content/10.64898/2026.04.07.716910v1
3 days ago
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2
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Partial EMT Drives Persistent Collective Migration via Collision Guidance in Heterogeneous Populations
https://www.biorxiv.org/content/10.64898/2026.04.07.714519v1
3 days ago
0
3
3
Curvature-mediated prewetting organize mitochondrial nucleoid
https://www.biorxiv.org/content/10.64898/2026.04.06.716811v1
3 days ago
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6
2
DNA-Functionalized Nanoparticles for Multicolor Cathodoluminescence Imaging
https://www.biorxiv.org/content/10.64898/2026.04.07.716901v1
3 days ago
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Direct Membrane Penetration of Oligoarginines by Fluorescence and Cryo-electron Microscopy Combined with Molecular Simulations
https://www.biorxiv.org/content/10.64898/2026.04.07.716952v1
3 days ago
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Critical amino acid residues in the N-terminal domain of NADPH-dependent assimilatory sulfite reductase flavoprotein mediate octameric assembly
https://www.biorxiv.org/content/10.64898/2026.04.08.717228v1
4 days ago
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Molecular basis for ligand-gating of the human GluD1 receptor
https://www.biorxiv.org/content/10.64898/2026.04.06.716743v1
4 days ago
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1
1
Modeling disorder, secondary structure formation, and amyloid growth in FG-nucleoporins
https://www.biorxiv.org/content/10.64898/2026.04.07.716937v1
4 days ago
0
2
2
Protein Language Models Encode Evolutionary Grammar but Conflate Topological and Thermodynamic Phases
https://www.biorxiv.org/content/10.64898/2026.04.07.717117v1
4 days ago
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Intrinsically disordered ligands for the control of receptor uptake by endocytosis
https://www.biorxiv.org/content/10.64898/2026.04.06.716760v1
4 days ago
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1
1
Theoretical estimate of the effective pKa of titratable lipids using continuum electrostatics
https://www.biorxiv.org/content/10.64898/2026.04.06.716676v1
4 days ago
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The low-field effect in radical pairs: a zero-field singlet-triplet basis picture
https://www.biorxiv.org/content/10.64898/2026.04.05.716627v1
4 days ago
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1
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Energetic analysis of Na+/K+-ATPase using bond graphs
https://www.biorxiv.org/content/10.64898/2026.04.05.716446v1
4 days ago
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1
1
PI(4,5)P2-dependence of GABAA receptor channel function revealed by optogenetic manipulation of a binding site
https://www.biorxiv.org/content/10.64898/2026.04.06.715776v1
5 days ago
0
1
1
Design of Fluorescent Membrane Scaffold Proteins for Nanodiscs
https://www.biorxiv.org/content/10.64898/2026.04.07.716332v1
5 days ago
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1
1
Allosteric Mechanisms Underlying Long QT Syndrome Type 2 (LQT2) Associated Mutations in hERG Channels
https://www.biorxiv.org/content/10.64898/2026.04.05.715988v1
5 days ago
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1
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A Spin-Glass Metabolic Hamiltonian optimized by Quantum Annealing Reveals Thermodynamic Phases of Cancer Metabolism
https://www.biorxiv.org/content/10.64898/2026.04.05.715441v1
5 days ago
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Disruption of Drosophila melanogaster Larval Locomotion Caused by Silver Ions
https://www.biorxiv.org/content/10.64898/2026.04.03.716380v1
5 days ago
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Reciprocal-space mapping of diffuse scattering by serial femtosecond crystallography reveals analog-specific disorder in insulin analogs
https://www.biorxiv.org/content/10.64898/2026.04.03.716400v1
5 days ago
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Structural principles of transcriptional collisions
https://www.biorxiv.org/content/10.64898/2026.04.06.716678v1
6 days ago
0
3
1
Cryo-EM elucidation of stoichiometric plasticity, asymmetric ligand recognition and allosteric coupling in human P2X2/3 heterotrimeric channels
https://www.biorxiv.org/content/10.64898/2026.04.04.716525v1
6 days ago
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1
1
Doubling the Field of View in Common-Path Digital Holographic Microscopy via Wavelength Scanning and Polarization Gratings
https://www.biorxiv.org/content/10.64898/2026.04.03.716314v1
6 days ago
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Structural Mechanism of TRPC3 Channel Activation by the Moonwalker Mutation
https://www.biorxiv.org/content/10.64898/2026.04.03.716262v1
6 days ago
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Unravelling the plausible metal-dependent catalytic mechanism of Inositol monophosphatase ortholog from Pseudomonas aeruginosa through the lenses of macromolecular crystallography and enzyme kinetics
https://www.biorxiv.org/content/10.64898/2026.04.06.716684v1
6 days ago
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High-speed 3D single-virus tracking reveals actin-aided viral trafficking of SARS-CoV-2 on the plasma membrane
https://www.biorxiv.org/content/10.64898/2026.04.03.716319v1
6 days ago
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Binding Structures, Mechanical Properties, and Effects on Cellular Behaviors of Extracellular Matrix Proteins on Biomembranes
https://www.biorxiv.org/content/10.64898/2026.04.03.716427v1
6 days ago
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1
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PRISM: A High-Throughput Simulation Infrastructure for CADD Agents
https://www.biorxiv.org/content/10.64898/2026.04.02.716083v1
6 days ago
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Impact of intercalators on the properties of DNA analyzed by molecular dynamics simulations
https://www.biorxiv.org/content/10.64898/2026.04.02.716032v1
6 days ago
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A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through In Silico Construct Optimization and de novo Protein Design
https://www.biorxiv.org/content/10.64898/2026.04.02.716066v1
6 days ago
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Repeatable quantum-hardware execution of a fast local-topology surrogate for hyperthermal sarcomeric oscillations
https://www.biorxiv.org/content/10.64898/2026.04.02.716025v1
7 days ago
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