Why can cells keep protein aggregation under control for years and then suddenly tip into disease? Our new JCP paper introduces a simple phase-plane model for in vivo protein aggregation that captures the tug-of-war between aggregate formation and clearance in cells. pubs.aip.org/aip/jcp/arti...

Thrilled to see our recent preprint on tipping points in neurodegeneration highlighted on Alzforum! Read it here: www.alzforum.org/news/researc.... Many thanks to Jessica Shugart for the engaging coverage, and to everyone involved in this exciting project at the @ukdri.ac.uk and elsewhere!