New work from @henrikstrahl.bsky.social and coworkers!

“The” Fenway? “The” Seaport? Residents are split on using “the” before certain Boston neighborhood names. Where do you land?

PTC Therapeutics has shared 2-year data on votoplam, a once-daily HTT-lowering pill. In Stage 2 participants, results suggest up to 52% slowing of disease progression. Let's go through what the data show, what’s still unclear, and how the Phase 3 trial is taking shape. en.hdbuzz.net/two-years-in...

New book coming out in the Methods in Enzymology series, on Structural studies of #amyloid beta: www.sciencedirect.com/bookseries/m... Edited by Rob Tycko (NIH) and Wei Qiang (Binghamton University). With a range of topics included, from experimental to computational.

Been training for this moment my whole life.

Are there any really good examples of institutional preprint policies? not funders but universities or research institutions. I'm looking for case studies for a preprint course I'm putting together :) #preprint #academicsky#openscience

PhD opportunity- fully funded with stipend, fees and project costs covered. Explore the role of phosphite in treating kauri dieback disease. Applications due 8th May. Please spread the word! newzealandecology.org/phd-explorin...

De heen- en terugreis waren vandaag precies lang genoeg om weer ademloos naar deze boeiende aflevering van @betrouwbarebronnen.bsky.social te over #Lafayette luisteren. Al was het maar om te weten wie die man is waar in Frankrijk zoveel avenues en rues vernoemd zijn. Dit keer met musical ipv opera

Fibrillation of the Pseudomonas Extracellular Functional Amyloid FapC is Controlled by Oligomeric State, Hierarchical Architecture and the C-Terminus https://www.biorxiv.org/content/10.64898/2026.04.28.719052v1

April 2026 showed us a toxic HTT fragment is center stage in mouse research, CRISPR is showing promise in mouse studies, AI and wearables move closer to the clinic, and 2 studies shine a light on the weight carried by HD caregivers. Full Article: en.hdbuzz.net/april-2026-t...

Very pleased to announce the 3rd Berlin Single Molecule Biophysics Course, this September 14th-18th. We now include more single molecule microscopy, with @ewerslab.bsky.social and Maximillian Ulbrich joining Jelena Baranovic and Claudio Grosman as tutors. Apply @ [email protected] by 12th June!

A little light reading on a rainy day in Waltham. thanks as always @jeremymberg.bsky.social

I wrote 6 editions of Biochemistry which was lots of fun when it was not threatening to do me in. I am now the only survivor of that author team, but we now have a great team of new authors (who all worked hard on the last (10th edition) with me). Lubert's book turned 50 last year.

Cooperative Control of Arrestin Activation By Membrane Lipids And Phosphorylation Barcodes pubmed.ncbi.nlm.nih.gov/42039491/ #cryoem

How much does it cost to buy your way onto a scientific paper? To answer this question (and better understand the global market for academic reputation manipulation), we compiled BuyTheBy, a massive dataset of thousands of advertisements from paper mills in seven different countries. Link below!

New equipment expands DNP-NMR research capabilities at Ames Lab www.ameslab.gov/news/new-equ... #NMRchat 🧲

Update: molecules!

🚨A warm welcome to our sixth plenary speaker! 📷 Prof. Melinda Duer, University of Cambridge. More info at: euromar2026.mkon.se/speakers #NMR #MRI #EPR #ESR #EUROMAR2026

🚨Our tenth plenary speaker: 📷 Prof. Raphaële Clément, MPI for Solid State Research. More info at: euromar2026.mkon.se/speakers #NMR #MRI #EPR #ESR #EUROMAR2026

New perspective on caveolae www.nature.com/articles/s41...

Had a great time at the Microbiology Society Annual Conference! I gave a talk on modelling protein-protein interactions with AlphaFold3. A few lessons learned 🧬🧵

Please repost! This comes from the good people at ChimeraX, who produce powerful up-to-date software to study protein (etc) structures, which are FREE to the community. 🙏 To stay viable and serve us, they need an experienced structural biologist to assume the leadership role on a funded project.

Man Finally Good Enough At New Hobby To Understand How Bad He Is At It

Camera delle Cariatidi, Villa Imperiale, Pesaro. Decorated for Eleanora Gonzaga in around 1530, by Dosso & Battista Dossi. Today is their day.

Unwelcome advice is not always wrong: You should be writing.

It arrived. Looking forward to reading this book after hearing good things about it. #huntingtonsdisease

Full-Length Molecular Models of Brain-Derived α-Synuclein Fibrils Reveal a Fuzzy-Coat-Mediated Mechanism for Selective Peptide Binding www.biorxiv.org/content/10.64898/2026.04.16.718707v1 #cryoem

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.

When to submit targets: NOW - July 10, 2026. How to submit targets: predictioncenter.org/casp17/callF...

“Eerder is wel geopperd om met onaangekondigde bezoeken te gaan werken.” ukrant.nl/tweede-kamer...

That’s Eric Idle’s point. Stay positive even when life’s a piece of shit (when you look at it). Still the most popular song at British funerals.

Betrouwbare Bronnen 580 👉Lenteboekenspecial 📚Nieuwe boeken 📚Over unieke vrouwen, ideologen, ballingen, sublieme schrijvers, politici, denkers en grote liefdes 📚https://omny.fm/shows/betrouwbare-bronnen/580-lenteboekenspecial

IKEA assembly 🤯

Thrilled to share that our latest work is featured on the cover of the current issue of @chemistryeurope.bsky.social! Read the full paper here: doi.org/10.1002/ceur.70264 🧪 #chemsky #MOFs #FlueGasDesulfurization

I thought somehow this was a @inprep.bsky.social post

They got the name from this paper. LMFAO. ciencias.ulisboa.pt/sites/defaul...

Tomorrow is #GivingDay at @vanderbilt.edu. Your gift to the Dr. Anne Karpay Award in Structural Biology supports a senior graduate student who well-rounded, collaborative, collegial and has performed exceptional research in structural biology. www.givecampus.com/campaigns/57...

Bluebird posting will continue until morale improves 🪶

The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year. Applications are open now! More details: mrclmb.ac.uk/careers-and-... Please share this post with anyone who may be interested!

Spent today at Radboud University in Nijmegen for the PhD defense of Angel Wong. Great job with lots of cool #ssNMR and a very detailed scientific discussion. Congrats to Dr Wong!

The nonprofit that runs the successful, Pulitzer-winning Baltimore Banner is going to take over the Pittsburgh Post-Gazette. Of all the possible outcomes here, this is likely the best we could have hoped for. apnews.com/article/pitt...

Great presentation by @francesarnold.bsky.social for the Backer lecture this afternoon! Organized by the Backer Foundation (www.backerfoundation.nl), held at the @rug.nl . About evolving an designing novel enzymes. Very cool! (With quite some machine learning and even some DISCO )

Behold Arachnocampa luminosa, aka the New Zealand glowworm. The larval forms use their blue-green bioluminescence to lure prey into silk snares (meanwhile, the adults take the form of tiny gnats).

It is saddening to watch foundations of US scientific research fall apart. But Europeans are not going to sit in a corner and bemoan fate. They and the rest of the world have no choice but to develop the capacity needed to compensate for the erosion of American state capacity