Bay Bridge, Maryland

A new paper in #ScienceSignaling visualizes the delicate ebb and flow of receptors within neurons via the unusual process of transcytosis—helping answer how these cells maintain their function and connectivity in vivo despite their spindly, elongated nature. https://scim.ag/4dlUGl8

Some moments between teaching microscopy at @mblscience.bsky.social in Woods Hole.

It was an honor to hear Prof. Sarah Veatch, PhD, deliver yesterday’s Inoué Lecture, discussing how spatiotemporal pair-correlation analysis can recover nanoscale membrane organization in live-cell single-molecule localization #microscopy despite diffusion and molecular motion. #MBL 🌊 #AQLM 🧫

OK, here we go. This is the good stuff. An awesome and technically innovatie new paper by good friends of mine including @profsharona.bsky.social, Bill Zagotta, and my next-door science neighbors Professor Suzanne Hoppins and grad student Sophie Hurwitz. 1/

Hydrozoa from Eel Pond @mblwoodshole imaged in dark field on an @evidentmicroscopy upright #microscope (cool to be able to tile and stitched on the go with a manual stage). These cuties are related to jellyfish, sea anemones and corals. 📸 Photo and caption credit: Nat Prunet @microscopic_farmer

#ScopeTheScope at AQLM Day 1 : Ray optics with Prof. Alexa Mattheyses, PhD. Up next: Building a microscope in the very first lab 👀 @mattheyseslab.bsky.social #MBL 🌊 #AQLM 🧫 #Microscopy 🔬 #BioImaging 🧬 #Fluorescence🪼#WoodsHole 🦞 #Optics 💡 #LightMicroscopy 🧪 #STEMCommunity 🫂 #ScientistLife 🧑‍🔬

Throwing the switch for our electron microscope installation. With these fabulously complex instruments, something always goes wrong at first light. Roseann Rosanna Danna’s (Gilda Radner) expression, “It just goes to show you, it’s always somethin’” is powerfully accurate.

Excited to share that my 2025 collection of science-inspired drawings is now live on the Protein Data Bank (PDB) website. Thank you @rcsbpdb.bsky.social! It is free to explore and download. I’d love to hear what you think! pdb101.rcsb.org/sci-art/bezs...

Our preprint on Antarctic fish cell cultures is out now! Loads of pretty nice super-resolution images. Read it here: www.biorxiv.org/content/10.6...

False Indigo and paw paw flowers

New perspective on caveolae www.nature.com/articles/s41...

Congratulations to @juanbonifacino.bsky.social at the NIH on his election to the American Academy of Arts and Sciences — one of the nation's most prestigious honorary societies — in recognition of his distinguished contributions to cellular and developmental biology! 🎉 www.amacad.org/new-members-...

Dr. Swee Lay Thein of NHLBI shared the 2026 Breakthrough Prize for her work on sickle-cell disease and beta-thalassemia. breakthroughprize.org/Laureates/2/...

Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...

We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️

West Virginia

The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

There are an extremely limited number of open slots for the Analytical and Quantitative Light Microscopy @aqlm.bsky.social course at @mblscience.bsky.social April 29-May 8 2026. www.mbl.edu/education/ad... Apply here for this amazing opportunity!

Emma Burns, Anastasia Amoiroglou, Gregory Rogers, Nasser Rusan and colleagues develop an expansion microscopy protocol for Drosophila cultured cells and tissues, which they use to dissect centriole biology. journals.biologists.com/jcs/article/...

Prime numbers 2-4999, animated with ggplot2+gganimate. #Rstats code: gist.github.com/stephenturne...

Don't miss out. Apply to our 2026 Advanced Research Training Courses today!

🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social

DC, Winter 2025

My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...

We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki. His extraordinary generosity will bolster our renowned research and education programs. 🔬 Learn more: bit.ly/452WL1m

Hoya bloom

Woods Hole, MA

Salt Lake from the air

Metro

I am excited to share our first Pt replica EM images. It took us a little while, but now we have establish the unroofing, drying and Pt coating workflow 🎉 Great work by our postdoc Luis Wong Dilworth! The image below shows the cytosolic membrane leaflet of a fibroblast 👇

I'd like to draw your attention to this truly excellent paper from the Taraska lab on cryoET of plasma membrane associated proteins. Everyone who is thinking about probes in the cryoET space should also see what they could do with ferritag (fig 6) www.nature.com/articles/s41...

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration https://www.biorxiv.org/content/10.1101/2024.12.31.630838v1

It’s incredibly exciting when a completely different approach supports an unexpected finding from your group. Recently, we published that LDLR is captured with EGFR and FGFR1 at clathrin sites after EGF stimulation. I love science. www.molbiolcell.org/doi/full/10.... bsky.app/profile/scie...

In a new #ScienceSignaling study, researchers introduce extracellular #TurboID, a refinement of the popular proteomics tool that interrogates #ProteinProteinInteractions on the exterior cell membrane, and characterize interactions between #EGFR and #LDLR. scim.ag/3DgfJr9

Analytical and Quantitative Light Microscopy (AQLM) application deadline December 16 for full consideration! @aqlm.bsky.social @mblscience.bsky.social www.mbl.edu/education/ad...

Ginko

Kirkjufell, Iceland

Redwoods, Armstrong Woods, Sonoma County, CA