This is an impressive milestone!

The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot doi.org/10.7554/eLif... Great work by @labouessemarie.bsky.social and her student Alina! Congrats

Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...

Neuropixels + Optogenetics = Neuropixels Opto Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors. Today in @natmethods.nature.com doi.org/10.1038/s415... Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.

Out today in @natneuro.nature.com What started as a great discussion at an amazing meeting organized by @joaofoliveira.bsky.social culminated in our new Perspective on how #astrocyte functions operate across multiple spatial scales. Read: rdcu.be/fk0B7 Full text: www.nature.com/articles/s41...

Absolutely stunning work: de novo designed miniproteins targeting GPCRs as potent agonists and antagonists. This opens countless possibilities for programmable signaling, cleaner therapeutics, and faster drug discovery. Protein design is coming for pharmacology. 🚀 doi.org/10.1038/s415...

Very cool to see the power of de novo design applied to dye-labeling!

🚨Exiting new preprint from Lerner Lab postdoc AJ Miller-Hansen examining the thalamus as a physiological driver of local, acetylcholine-dependent dopamine release! 🚨 DA-ACh interactions have been 🔥but what’s really going on in vivo? We think we have some answers. #neuroskyence🧪

Check out the birghtest star in the room: PinkyCaMP - the latest member to the red GECI family! Amazing work led by Olivia Masseck and a wonderful team! Proud to contribute

Amazing piece on Locus Coeruleus neurons! Great work

This will be a great conference!

Wait… localized norepinephrine transients in the awake visual cortex?! Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. @ruedigersarah.bsky.social www.nature.com/articles/s41...

Wow - this is really amazing work, congrats to the whole team!

Nikki Tjahjono’s PhD work is out as a @cellpress.bsky.social preview in @ssrn.bsky.social! With @isacofflab.bsky.social, we introduce iHaloGluSnFR, the first red-shifted chemigenetic glutamate sensors, optimized for simultaneous imaging with neuromodulators. papers.ssrn.com/sol3/papers....

Norepinephrine imaging, pushed further. Our latest NE sensors enable highly sensitive monitoring across recording modalities, Have you been using GRABNE2 sensors? the toolkit just got a major upgrade. Interested in trying them in your system? Reach out.

Improved red and green indicators for norepinephrine detect norepinephrine release in awake behaving mice. @tpatriarchi.bsky.social www.nature.com/articles/s41...

The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

Feels like a pivotal moment. The president is screening a movie about his third wife and crying about a lawsuit challenging his guilded ballroom, while good-hearted Americans looking out for their neighbor are getting murdered by state police. Will Americans finally wake up?

Excited to share our new preprint! We explore the link between the locus coeruleus (LC) and arousal for astrocytes, pyramidal cells, interneurons in the hippocampus. A fantastic collaboration with @sianduss.bsky.social @bohaceklab.bsky.social, and many others: www.biorxiv.org/content/10.6... 1/5

An engineered nanobody inhibitor for molecular-to-circuit control of opioid receptor function. This was a really fun collaboration with @miriamstoeber.bsky.social and @amanglik.bsky.social labs, check it out! www.biorxiv.org/content/10.6...

Time-resolved fluorescent proteins expand fluorescent microscopy in temporal and spectral domains. Is it impressive? Yes Is it new? No Should you use it? Probably not. www.cell.com/cell/fulltex...

Congrats Martin, great work!

Amazing work by the Andermann Lab showcasing a perfect use-case for FLIM imaging of dopamine sensors - looking at tonic [DA] changes and adaptations over days! Honored to be part of this effort.

#BlueskyResistance #Voices4Victory #ProudBlur Advertisement at a London bus stop. Ya gotta love the British…

www.nature.com/articles/s41... This study is absolutely mind-blowing.

Congratulations Tal!! It's so great to see this out, I am very happy for you and your lab!!

Our lab has an open PhD student position in Protein Engineering - Neurotechnology. Apply if interested!

Amazing work by @massecklab.bsky.social PinkyCaMP the first mScarlet based Ca2+ indicator! Congrats to all, proud to have contributed to this

Extremely proud to see my second PhD student (now Dr.) Xuehan Zhou defending her thesis so brilliantly and successfully! Such happy moments :)

Our lab is looking for a motivated Research Assistant with hands-on experience with molecular cloning techniques, mammalian cell culture and confocal imaging. If you are interested in joining or know anyone who is, please email me your application. Thanks

This is really fascinating work, congrats to the whole team!

OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019). The renamed: Bluesky-sized history of neuroscience (biased by my interests)