Matteo Carandini
@carandinilab.net
š¤ 2588
š„ 434
š 107
Neuroscientist at University College London (www.ucl.ac.uk/cortexlab). Opinions my own.
pinned post!
New by AgnĆØs Landemard (
@agnesland.bsky.social
ā¬) & co Brainwide blood volume reflects opposing neural populations Brainwide fluctuations in blood volume arise from two populations with opposite relation to brain state and distinct relationships to blood supply
www.biorxiv.org/content/10.1...
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3 months ago
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TJ McIntyre
2 days ago
So, apparently big tech firms are telling employees to get back to the US before midnight eastern time tonight, or else avoid returning entirely until there is more clarity. ĀÆ\_(ć)_/ĀÆ
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Big Tech and finance companies are telling H-1B employees to get to the US in under 24 hours
Amazon, Microsoft, JPMorgan, and Meta employees on H-1B visas were told to stay put, per employees and communications reviewed by Business Insider.
https://www.businessinsider.com/big-tech-employees-h-1b-visa-travel-return-trump-eo-2025-9
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Valentin Schmutz
3 days ago
š "High-dimensional neuronal activity from low-dimensional latent dynamics: a solvable model" will be presented as an oral at
#NeurIPS2025
š Feeling very grateful that reviewers and chairs appreciated concise mathematical explanations, in this age of big models.
www.biorxiv.org/content/10.1...
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Enny van Beest
6 days ago
Join the 2025 UCL Neuropixels course (free and online!), 22-24th of October: Day 1 and 2: Get started with the basics and the latest updates on hardware & software. Day 3: Focus on how to analyse the many neurons you recorded. More info and to register:
www.ucl.ac.uk/neuropixels/...
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2025 Neuropixels course
A free online course on Neuropixels, 22-24 October 2025
https://www.ucl.ac.uk/neuropixels/training/2025-neuropixels-course
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For a reasonable person, it is hard to imagine how racist are the views of Elon Musk. In his view immigrants cause "rape and murder and the destruction of the country and dissolution of the entire way of life". His words are disgusting.
www.standard.co.uk/news/uk/elon...
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What did Elon Musk say at the Unite the Kingdom march? Speech in full
Elon Musk called for āmassive government reformā and warned āviolence is comingā to the UK
https://www.standard.co.uk/news/uk/elon-musk-unite-the-kingdom-march-speech-in-full-b1247841.html
7 days ago
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Nick Steinmetz
10 days ago
Exciting opportunity here - if you have a dataset and want IBL staff to run pipelines, develop visualizations or websites, work on QC, etc - or if you want to work on the IBL dataset in a way that needs staff support - then this is for you! Check it out.
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Emilie MacƩ
11 days ago
Thrilled to share that our work is now published in Science! ⨠We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! š§
www.science.org/doi/10.1126/...
š§µ1/
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Bluesky is not available in Mississippi!
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12 days ago
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Oded Rechavi
12 days ago
Full professor complaining to an assistant professor on how hard it is to get funding nowadays
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Here is the Wikipedia entry for Crimes Against Humanity:
en.wikipedia.org/wiki/Crimes_...
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12 days ago
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Selina Wray
12 days ago
www.bbc.com/news/article...
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Alzheimer's blood test could 'revolutionise' diagnosis
Scientists leading the trial at University College London believe the blood test could improve the accuracy of diagnosis of the disease to more than 90%.
https://www.bbc.com/news/articles/cm2ze84e8p1o
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Michael Schartner
13 days ago
nightscience.buzzsprout.com/1744020/epis...
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76 | Can Googleās Co-scientist project give scientists superpowers? - Night Science
To answer this question, we speak with Dr. Alan Karthikesalingam and Vivek Natarajan from Google DeepMind about their groundbreaking AI co-scientist project. Beyond their work at Google, Alan is an ho...
https://nightscience.buzzsprout.com/1744020/episodes/17807027-can-google-s-co-scientist-project-give-scientists-superpowers
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If you're into podcasts, here's a good one on the
@intlbrainlab.bsky.social
brainwide map, by
@newscientist.com
www.newscientist.com/podcasts/fir...
13 days ago
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Nature
3 months ago
First independent survey of deaths in Gaza reports more than 80,000 fatalities The results align with other efforts to count the number of people killed amid the ongoing conflict.
https://go.nature.com/44nH0la
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First independent survey of deaths in Gaza reports more than 80,000 fatalities
Results align with other efforts to count the number of people killed amid the ongoing conflict.
https://go.nature.com/4nocZdD
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Tomorrow it's sunny and windy in the UK so electricity is free from 12 pm to 2 pm!
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16 days ago
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International Brain Laboratory
19 days ago
If you have a project idea (experiment or theory!) please apply to become an IBL partner:
internationalbrainlab.com/ibl-core-apply
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Apply to work with the IBL Core ā International Brain Laboratory
https://internationalbrainlab.com/ibl-core-apply
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UCL Faculty of Brain Sciences
18 days ago
The first complete activity map of decision-making in the animal brain has been unveiled by a large international collaboration of neuroscientists involving
@uclqsion.bsky.social
and
@ucleye.bsky.social
researchers.
www.ucl.ac.uk/news/2025/se...
@kenneth-harris.bsky.social
@carandinilab.net
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Complete brain activity map revealed for the first time
The first complete activity map of decision-making in the animal brain has been unveiled by a large international collaboration of neuroscientists involving UCL researchers.
https://www.ucl.ac.uk/news/2025/sep/complete-brain-activity-map-revealed-first-time
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New Scientist
19 days ago
The first complete activity map of a mammalian brain has revealed unprecedented insights into how decisions are made ā and may even hint at the roots of intuition.
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First map of mammal brain activity may have shown intuition in action
Scientists have mapped the activity that takes place across a mouse's entire brain as it decides how to complete a task - and the results could explain the origin of our gut feelings
https://www.newscientist.com/article/2494850-first-map-of-mammal-brain-activity-may-have-shown-intuition-in-action/?utm_medium=SOC&utm_source=Bluesky#Echobox=1756912859-3
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Simons Foundation
19 days ago
The āŖ
@intlbrainlab.bsky.social
published 2 papers today on their work to create a map of neural activity across the entire mouse brain. Learn more about the lab:
https://www.simonsfoundation.org/2025/02/20/how-do-our-brains-make-decisions-the-international-brain-laboratory-is-closing-in-on-answers/
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How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers
How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers on Simons Foundation
https://www.simonsfoundation.org/2025/02/20/how-do-our-brains-make-decisions-the-international-brain-laboratory-is-closing-in-on-answers/
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International Brain Laboratory
19 days ago
Two flagship papers from the International Brain Laboratory, now out in āŖ@Nature.comā¬: š§ Brain-wide map of neural activity during complex behaviour:
doi.org/10.1038/s41586-025-09235-0
š§ Brain-wide representations of prior information in mouse decision-making:
doi.org/10.1038/s41586-025-09226-1
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Sainsbury Wellcome Centre
19 days ago
A complete brain-wide activity map at single-cell resolution has been revealed for the first time. Researchers recorded from 650,000+ neurons across 279 brain areas to track decision-making in mice. Read the story: š
www.sainsburywellcome.org/web/research...
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The two key studies of the International Brain Laboratory
@intlbrainlab.bsky.social
are out today! A brain-wide map of neural activity during complex behaviour
www.nature.com/articles/s41...
Brain-wide representations of prior information in mouse decision-making
www.nature.com/articles/s41...
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A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
https://www.nature.com/articles/s41586-025-09235-0
19 days ago
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Magdalena Skipper
25 days ago
āWe donāt see an epidemic of autism, but we see an āepidemicā of diagnosesā A fresh journalistic look at the rise in autism that brings together perspectives from the researchers & the autism community š§Ŗ
#MedSky
@nature.com
by
@helenpearson.bsky.social
www.nature.com/articles/d41...
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Autism is on the rise: whatās really behind the increase?
RFK Jr has vowed to find out whatās responsible, but scientists say he is ignoring answers from decades of research.
https://www.nature.com/articles/d41586-025-02636-1
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Eric Topol
25 days ago
A randomized trial of for eye care by ophthalmologists with A.I. vs ophthalmologists without A.I. demonstrated much higher accuracy in diagnosis (92 vs 74%) and many other improved outcomes @NatureMedicine
www.nature.com/articles/s41...
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Bence Ćlveczky
28 days ago
Wrote a eulogy for the yellow letters in my office window.
www.thecrimson.com/article/2025...
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My Lab Displayed A Message of Solidarity on Our Windows. Harvard Took It Down. | Opinion | The Harvard Crimson
If we continue down this path, we risk not only Harvardās future as an institution of free inquiry and expression but also its integrity and trustworthiness.
https://www.thecrimson.com/article/2025/8/25/olveczky-harvard-blm-sign/
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Dorothy Bishop
about 1 month ago
Now thatās what I call a special issue
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Tim Verstynen
about 1 month ago
This had me laughing to tears. The person sitting next to me on the flight must have thought I was nuts. A must read for the FEP curious.
www.researchgate.net/publication/...
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(PDF) The Exit Manual: How to Leave the Free Energy Cult and Still Get Tenure
PDF | This manual is not a plea. It is a jailbreak from a cultāthe Free Energy Principle, a theoretical metastasis that began in computational... | Find, read and cite all the research you need on Res...
https://www.researchgate.net/publication/391807467_The_Exit_Manual_How_to_Leave_the_Free_Energy_Cult_and_Still_Get_Tenure
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Sten Linnarsson
3 months ago
A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)
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about 1 month ago
It was an honor to write this, but also great fun. A chance to look back at the classics, and think about the path forward.
#Physics
is a beautiful human endeavor.
journals.aps.org/prxlife/abst...
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Emergence of Brains
This review traces how ideas from statistical physics evolved into foundational models of neural computation, shaping modern AI and culminating in the 2024 Nobel Prize in Physics.
https://journals.aps.org/prxlife/abstract/10.1103/62p9-wn32
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Reese Richardson
about 2 months ago
Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community.
reeserichardson.blog/2025/08/04/a...
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A do-or-die moment for the scientific enterprise
Reflecting on our paper āThe entities enabling scientific fraud at scale are large, resilient, and growing rapidlyā
https://reeserichardson.blog/2025/08/04/a-do-or-die-moment-for-the-scientific-enterprise/
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Rita Strack
about 2 months ago
I have some BIG NEWS to share today! Today I begin my next adventure as Chief Editor of Nature Biomedical Engineering!! (a thread)
@natmethods.nature.com
@natbiomedeng.nature.com
@natureportfolio.nature.com
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Michael Schartner
about 2 months ago
Using the
@intlbrainlab.bsky.social
BWM dataset, which comprises electrophysiological recordings of 60 k neurons covering one mouse brain hemisphere, we find all brain regions contain most neural response types, i.e. function is widely distributed:
www.biorxiv.org/content/10.1...
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Dean Buonomano
about 2 months ago
It looks like all NSF/NIH grants to UCLA (including mine and all fundamental neuroscience grants) have been suspended.
www.science.org/content/arti...
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NSF and NIH suspend grants to UCLA
Move follows Trump administration finding that school didnāt effectively combat antisemitism
https://www.science.org/content/article/nsf-and-nih-suspend-grants-ucla
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The Transmitter
about 2 months ago
Some neurons respond more strongly to visual stimuli than others. But the rest of the brain doesnāt prioritize signals from those neurons, according to a new study. Read more in this monthās Null and Noteworthy. By
@ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
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Null and Noteworthy: Downstream brain areas read visual cortex signals en masse in mice
The finding contradicts a theory that the regions prioritize neurons that are adept at identifying specific stimuli. Plus, a response to a study that questioned immune memory in astrocytes.
https://www.thetransmitter.org/null-and-noteworthy/null-and-noteworthy-downstream-brain-areas-read-visual-cortex-signals-en-masse-in-mice/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250731-null-noteworthy-downstream-brain-areas-read-visual-cortex
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Loren Looger lab
about 2 months ago
so proud of this team!!! they're changing the way grants are sought, written, and funded. and such critical work - greenhouse gases this cycle, focused on methane. they funded us (+ Michael Konopka, USNA) to study methane monooxygenase (pMMO), potentially the key to remediating methane pollution.
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Sam Gershman
about 2 months ago
This is unfortunate:
www.nytimes.com/2025/07/28/u...
I wrote to the president of Harvard. I hope other faculty will speak their conscience, even if it means more struggle ahead.
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Kevin Mitchell
2 months ago
Remote activation of place codes by gaze in a highly visual animal
www.nature.com/articles/s41...
- very cool study with chickadees!
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Remote activation of place codes by gaze in a highly visual animal - Nature
Place cells in the chickadee hippocampus coherently represent locations in space, whether physically visited or viewed, enabling spatial reasoning at a distance through a unified process coordinated b...
https://www.nature.com/articles/s41586-025-09101-z
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Spencer LaVere Smith
2 months ago
Wake up, babe. A new mapping stimulus just dropped.
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UCL Faculty of Brain Sciences
2 months ago
It is with great sadness that we announce the passing of beloved
@ucleye.bsky.social
colleague Prof Pete Coffey. A pioneer in stem cell therapy, his research has helped restore sight to people with macular degeneration. His legacy will continue to transform lives.
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Tribute to eye treatment pioneer Professor Pete Coffey
UCL colleagues have paid tribute to world-leading eye researcher Professor Pete Coffey, who pioneered a treatment enabling people whose vision had been destroyed by disease to see again.
https://www.ucl.ac.uk/news/2025/jul/tribute-eye-treatment-pioneer-professor-pete-coffey
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Introducing our new favorite stimulus. A few minutes are enough to map the visual preferences of thousands of neurons. Mapping the visual cortex with Zebra noise and wavelets
www.biorxiv.org/content/10.1..
. By Sophie Skriabine and Max Shinn, with Samuel Picard and
@kenneth-harris.bsky.social
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2 months ago
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The Commission is pushing for a massive increase in funding for Horizon Europe 2028-2034. If I understand correctly, Pillar I, which includes
@erc.europa.eu
and Marie Sklodowska Curie fellowships, would go from the current ā¬25 billion to ā¬44 billion. Let's hope it happens!
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2 months ago
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Petr Znamenskiy
2 months ago
1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and
@antblot.bsky.social
. š§µ
www.biorxiv.org/content/10.1...
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Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits
Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...
https://www.biorxiv.org/content/10.1101/2025.07.16.665048v1
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US students are increasingly applying to UK unis. They are at 6%, and rapidly growing. Makes sense: it costs less, lasts 3 years (typically), does not infantilize (re drinks). And no kidnapping by masked thugs (yet). However, courses focus on a single discipline. Link (paywall):
on.ft.com/4nYb1Ry
2 months ago
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Ken Miller
2 months ago
Abundant aid is sitting on the border, if IL would let it in. After complete blockade for months they now are allowing in only a trickle. That combination is creating the current, rapidly worsening situation. How many people must die of starvation before the world will pressure IL to open the gates?
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"I imagined that Russia would become more like America over the years ā instead, the opposite happened"
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2 months ago
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Per Engzell
2 months ago
i'm sorry my review is late i meant to read it weeks ago but the writing was actively hostile to comprehension each paragraph a slow erosion of my will to live
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Welcome to Bluesky
@kenneth-harris.bsky.social
!
2 months ago
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A new study led by
@timothysit.bsky.social
reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries.
www.biorxiv.org/content/10.1...
2 months ago
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The Guardian
2 months ago
Royal Society suggested to Elon Musk he consider resigning science fellowship
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Royal Society suggested to Elon Musk he consider resigning science fellowship
Exclusive: Fellows called on academy to act over Tesla ownerās role in Trump administrationās attacks on research The Royal Society suggested to Elon Musk he should consider resigning his fellowship if he felt unable to help mitigate the Trump administrationās attacks on research, the Guardian has learned. The owner of X, who is also CEO of Tesla and Space X, was elected a fellow of the UKās national academy of sciences in 2018 for his contribution to the space and electric vehicle industries. Continue reading...
https://www.theguardian.com/science/2025/jul/17/royal-society-elon-musk-resign-science-fellowship-tesla?utm_source=dlvr.it&utm_medium=bluesky&CMP=bsky_gu
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Fillip Port
2 months ago
Hey
@nature.com
What's up with your share buttons? Can we please also get š¦ and 𦣠options to not exclusively promote the network of the guy who has done more than most to harm US science?
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