🧠✨ Women in Neuroscience History: The Pioneers Who Changed Everything Incredible stories of 11 women who revolutionized brain science, often against impossible odds. Meet trailblazers of sleep research, memory science, neuroplasticity, and neurosurgery — from Maria Manasseina to May-Britt Moser 🧠

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

Following up: searching for the distribution of estrogen receptors in the brain, I realized the Allen Brain Atlas is male only. How is it possible that something this fundamental is still missing?

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

Our latest profile just dropped! Dr. Emily Jacobs (‪@emilyjacobs.bsky.social‬) studies how hormonal fluctuations influence the brain. Follow the link below to listen to the full interview! www.storiesofwin.org/profiles/202... #WomenInNeuroscience #StoriesOfWiN

Excited to announce that my lab has moved to UC Berkeley Dept of Neuroscience and Dept of Statistics! I will be continuing to collaborate with colleagues and students in TX at UT Austin and Baylor College of Medicine, and will start new collabs in the Bay. Will be taking new grad students this fall!

I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab! We explored how behavior, senses, and neurons influence how much information in the brain changes over time. www.nature.com/articles/s41... #science #research #neuroscience #hippocampus #placecells

Took a break from worrying about funding to do some climbing in Squamish! (Elowen’s first multi-pitch)

A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...

Can your AI beat a mouse? Mice still outperform our best computing machines in some ways. One way is robust visual processing. 10 years ago I decided to work on HARD behavior driven by COMPLEX visual processing. And that risk is paying off now. #neuroAI 1/n

The FY26 budget will devastate our innovation driven economy. A summary in 3 parts... Part 1 - The White House vision for dismantling science, as described in one simple plot, means slashing budgets of NIH, NASA, NSF & going back 25 years (or more). joshuasweitz.substack.com/p/the-white-...

Very happy to see a Transmitter (@thetransmitter.bsky.social) piece on our recent work on estrous cycle modulation of hippocampal structure and function. Thanks to Sydney Wyatt (@sydneywyatt.bsky.social) for covering the work and its context: www.thetransmitter.org/neuroendocri...

Riddle: When is an "optical invariant" is not so invariant? How can you get a larger field-of-view for free? No change in resolution or scan speed. No more stitching needed! For #MicroscopyMonday here's a new preprint to check out. 1/9

Now out in @natcomms.nature.com‬: Mice and monkeys spontaneously shift through comparable cognitive states - and it's written all over their faces! (1/7) www.nature.com/articles/s41...

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

We’re international students at Harvard. We’re afraid to write this. But we have to speak up. www.washingtonpost.com/opinions/202...

Huge congrats, Will! Can't wait to see the work from your lab!

Online now:

🚨Very excited to share a new paper from our lab in Neuron (@cp-neuron.bsky.social) on the influence of the estrous cycle on structural and functional plasticity in the hippocampus: www.sciencedirect.com/science/arti... Thread below 🧠🧪🧵:

Join us in beautiful Santa Barbara! We're hiring a full-time junior specialist/research technician to play a central role in data collection & analysis of brain imaging studies of pregnancy & menopause. Learn more & apply at: recruit.ap.ucsb.edu/JPF02974 Or help us spread the word 💫

🚨New paper from the Epp and Sargin Labs!🚨 We identified early sex- and region-specific impairments to parvalbumin interneurons (PV-INs) during Alzheimer’s Disease (AD) pathogenesis www.science.org/doi/10.1126/... Simplified highlights below: 🧵/15

🚨new paper alert Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass. Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉 www.nature.com/articles/s41...

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪 Led by Ling-Xiao Shao and @ItsClaraLiao Funded by @NIH @NIMHgov 📄 Read in @nature.com - www.nature.com/articles/s41... 1/12

Check out our new paper, that reveals both the striking generality of cortical circuit organization, but also what we think are key differences in the scales of local excitatory and inhibitory networks across cortical areas. www.jneurosci.org/content/45/1...

Sex Differences Research Saves Lives! #OSSD #BoSD #SBN #SWHR #science please share rdcu.be/ecZXa

“[T]his is a moment to speak publicly about why universities matter. They promote public health, economic growth and national security. They are the largest employers in some regions. They are an unmatched, if imperfect, engine of upward mobility that can alter the trajectory of entire families.”

New "version of record" of our article on the effect of robust within-module grid cell variability on spatial coding in @elife.bsky.social. Check out @wtredman.bsky.social's explainer thread below:

1/12 How do animals build an internal map? In our new paper, we tracked thousands of mouse CA1 neurons over days/weeks as they learned a VR navigation task. @nspruston.bsky.social & co-1st author @johanwinn.bsky.social Video: www.youtube.com/watch?v=yw_4... Paper: www.nature.com/articles/s41...

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

New preprint from the lab: Disrupted spatial and contextual memory encoding in the hippocampus of 5xFAD mice precedes cognitive impairment. Yimei Li, Mary Ann Go, Hualong Zhang, Simon Schultz. www.biorxiv.org/content/10.1...

Perfect periodicity in grid cells would make decoding locations degenerate in large spaces. Slight distortions in grid patterns, as observed in vivo, solve this problem, enabling precise spatial navigation. Final version of the manuscript is now available 👇 elifesciences.org/reviewed-pre...

Early morning panel on Spatial Perception, Memory, and Navigation today @ 7:30am in the Pyramid Peak room! #wcbr

The antidote for despair is action ❤️ * Dial (202) 224-3121 * Enter zip code * Leave voicemail * Say “My name is ___, I’m a constituent in [town]. (If clinician/scientist, say so) “The NIH freeze harms research and patients and must be lifted immediately.” Be brief. Staffers tally all calls. Go! ✅

Wikipedia is one of the last major bastions of verified information. Which, of course, is why the oligarchs want to destroy it. You can donate to them here. donate.wikimedia.org/w/index.php?...

Attention! Zong lab is recruiting!! Two Ph.D and postdoc positions in neuroscience 🧠 are available!! Apply if you are strongly interested in applying cutting-edge @TheMini2P 🔬 for frontier systems neuroscience studies!!!! www.jobbnorge.no/en/available...

Happy head direction cell day y’all! On this day, 41 years ago, Jim Ranck recorded the first “HD cell” in his Brooklyn lab in 1984. Jim shared the news with the world at SFN that year, showing a video of the cell’s firing on a TV he somehow acquired and brought to his poster… (1/3)

Proud papa moment: Elowen finished her first year of bouldering competition with 2nd place in the Region (Southern California, Nevada, Utah, and Hawaii). So cool to see her improvement over the last year!

Hello BlueSky. One of our cofounders, Linde Jacobs, is profiled in The New York Times today. It’s a moving snapshot of what an FTD family goes through. Help us fight for therapies that can cure dementia for under 60s. #ftd #aftd #dementia #tau #alzheimers #mapt www.nytimes.com/2024/12/22/h...

Building egocentric models of local space from retinal input www.cell.com/current-biol... #neuroscience

Very interesting thread, though sadly an excellent example of Brandolini’s law

What an honor to join the White House Conference on Women’s Health Research and celebrate the incredible gains made over the past year. I am ever optimistic that progress will continue to accelerate at break-neck speed & across sectors.

One year ago, we launched the Ann S. Bowers Women’s Brain Health Initiative and what a year it’s been! From groundbreaking research to building a community of motivated and brilliant people, we’re proud to champion women’s brain health for generations to come.

I'm pleased to announce that the Version of Record of our eLife paper, "Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice" (Vickers and McCormick, 2024) is now available at: elifesciences.org/articles/94167 (94167.3, VOR).

🚨New(ish) preprint In mice, visual objects are encoded in the navigation syst, not much in the visual cx, certainly because they are used for orientation. This new version now includes cool comp work from @dlevenstein.bsky.social using @kenmiller.bsky.social's SSNs. www.biorxiv.org/content/10.1...

When we enter a new environment, we use visual input to rapidly build an internal model of the local spatial environment. How does our brain do this? We review past literature and suggest some new ways forward in our new review in @currentbiology.bsky.social: authors.elsevier.com/sd/article/S...

Terrific piece summarizing a recent report: Every dollar of NIH research funding doubles in economic returns www.fiercebiotech.com/research/rep...

Most viewed reel in Nature’s history?! 🎤💧 Let this be the rallying cry: women’s health can’t wait. @natureportfolio.bsky.social www.youtube.com/watch?v=m-nl...