The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum. If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

Great study showing how histaminergic signaling shapes head-direction cell activity in the presence of objects, with important implications for how animals get oriented. A huge amount of work, really impressive. www.researchsquare.com/article/rs-7...

A chemical extracted from carrot roots helped pave the way for flat-screen TVs, and six other discoveries that unintentionally changed the world. Perfect talking points for when you need to defend basic science, whether it’s to your grumpy uncle or your MP. www.nature.com/articles/d41...

🚨Job alert🚨 The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour This is part of a collaborative ARIA grant "4D precision control of cortical dynamics" euraxess.ec.europa.eu/jobs/383909

a gross parliamentary overreach — article by @picardonhealth.bsky.social in the globe and mail; #academicsky #neuroskyence #psychscisky www.theglobeandmail.com/gift/91587b9...

New lab colormap, courtesy of the tree outside my house.

Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo

Looking forward to seeing all the great science that will come out of @adrian-du.bsky.social’s lab, aka the DuLab!! Congrats Adrian!

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇 kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

Totally agree with @gershbrain.bsky.social. Science will never explain art. Yet the two share an important trait: a constant search for new representations of nature, of data, of reality, of emotions, in forms that make sense of what once seemed inscrutable.

The Wu Tsai Institute at Yale is hiring another faculty member in neurocomputation. Come work with us in a growing community at the interface of neuroscience and AI! More info below 👇

Every neuroscience lecture ever, summarized in one dog video.

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social ! With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

🚨 New paper in Nature Methods: HippoMaps: multiscale cartography of the human hippocampus Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG) Led by @jordandekraker.bsky.social docs: hippomaps.readthedocs.io paper: doi.org/10.1038/s415...

Just the most remarkable person and truly a beautiful soul

🕊️ The world has lost a revered conservationist -- a colossal power for what is truly good. 🕊️ Jane Goodall is a legend who helped open the door to science to the best humans among us: woman. 🕊️ She was brave, brilliant and introduced us to the best things among us: animals. 🕊️ I grieve her passing.

Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience. #neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...

Post-tenure mid-life crisis project: complete ✅ 3h27 at the marathon (PB!) and one very happy (if slightly zombie-like) man. Recovery phase starts now…

Fascinating work! It pinpoints the origin of dopaminergic signaling as a filter of striatal activity computing temporal difference. Excited to dig into this manuscript.

So happy to see Morgane Butler, a former and brilliant undergrad student in the lab, publishing her PhD work. Looks super interesting. www.nature.com/articles/s41...

Beautiful work showing a link between hippocampal theta sequence and learning, but not subsequent replay.

Turns out BTSP is not All You Need™️?

« Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells. » A fundamental study now published @elife.bsky.social elifesciences.org/reviewed-pre...

Finally preprinted! TL;DR: thalamic head-direction neurons can shape their activity regardless of input. Big thanks to @apeyrache.bsky.social and master experimentalist @sskromne.bsky.social .

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

Check this out. This is an amazing resource for teaching vision and neuroscience in general.

Processed a bunch of papers in the queue @biorxivpreprint.bsky.social. The queue hasn’t gotten any shorter 😢 #Sisyphus (480 papers in the queue, backlog of almost one week)

Does slow oscillation-spindle coupling contribute to sleep-dependent memory consolidation? Yes but explained variance is limited. Now published in @elife.bsky.social elifesciences.org/reviewed-pre...

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

So cool!

Fluorescent proteins can now act as qubits 🤯 This opens the door for single cell MRI in vivo and highly localized sensors that map magnetic fields, temperature gradients, etc. Insane. www.nature.com/articles/s41...

Following up: searching for the distribution of estrogen receptors in the brain, I realized the Allen Brain Atlas is male only. How is it possible that something this fundamental is still missing?

It's 2025, and there's apparently no female mouse atlas. Please, tell me I'm wrong.

Elevator ride is an underrated team building activity

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

New workshop! Just before SFN, join the Flatiron Institute Center for Computational Neuroscience of the Simons Foundation for a workshop on pynapple and NeMoS. Learn how to use these open-source packages to analyze and model neural data! Accommodation & meals provided. Link ⬇️

For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more #neuroskyence #academicsky

The point is now to make it middle school knowledge.

Sunday fun fact: A 3rd-century BC Roman coin depicting a hippocampus — the mythical sea creature linked to Neptune. One of 13,000 coins discovered while digging in the basement of a house in southern France, near the Pyrenees.

🚨 Preprint alert 🚨 The main results of my PhD are online and I only now could find some time to post about it! We explored the neurovascular activations of spatial navigation by using functional ultrasound imaging (fUSI) in freely moving rats during open field.

All the top arguments against the lab-leak theory of COVID-19, in a single email

« History shows that increasing wealth inequality consistently precedes collapse from the Classical Lowland Maya to the Han dynasty in China and the Western Roman empire » Nothing new, perhaps, but always worth repeating.

Fascinating Sunday read: some forms of untreatable schizophrenia may actually be misdiagnosed and curable. www.newyorker.com/magazine/202...

Trying to train RNNs in a biol plausible (local) way? Well, try our new method using predictive alignment. Paper just out in Nat. Com. Toshitake Asabuki deserves all the credit! www.nature.com/articles/s41...

Brenda Milner just turned 107. Happy birthday! On my very first day as a PI at the MNI, she was right in front of me in the cafeteria line. She was already nearly 100, and still coming to work. What a legend.

The thing about going on vacation with a multinational family… it always feels a bit like a spy movie.

This year, Canada Day feels extra special. It’s my first one as a Canadian citizen! 🇨🇦🎉

🧠🔬 This important study demonstrates that slow fluctuations in serotonin release during wakefulness and non-REM sleep correspond to periods of heightened arousal or enhanced offline information processing, especially in the hippocampus. Congrats to the authors! elifesciences.org/reviewed-pre...

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇