Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience. #neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...

Post-tenure mid-life crisis project: complete ✅ 3h27 at the marathon (PB!) and one very happy (if slightly zombie-like) man. Recovery phase starts now…

Fascinating work! It pinpoints the origin of dopaminergic signaling as a filter of striatal activity computing temporal difference. Excited to dig into this manuscript.

So happy to see Morgane Butler, a former and brilliant undergrad student in the lab, publishing her PhD work. Looks super interesting. www.nature.com/articles/s41...

Beautiful work showing a link between hippocampal theta sequence and learning, but not subsequent replay.

Turns out BTSP is not All You Need™️?

« Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells. » A fundamental study now published @elife.bsky.social elifesciences.org/reviewed-pre...

Finally preprinted! TL;DR: thalamic head-direction neurons can shape their activity regardless of input. Big thanks to @apeyrache.bsky.social and master experimentalist @sskromne.bsky.social .

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

Check this out. This is an amazing resource for teaching vision and neuroscience in general.

Processed a bunch of papers in the queue @biorxivpreprint.bsky.social. The queue hasn’t gotten any shorter 😢 #Sisyphus (480 papers in the queue, backlog of almost one week)

Does slow oscillation-spindle coupling contribute to sleep-dependent memory consolidation? Yes but explained variance is limited. Now published in @elife.bsky.social elifesciences.org/reviewed-pre...

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

So cool!

Fluorescent proteins can now act as qubits 🤯 This opens the door for single cell MRI in vivo and highly localized sensors that map magnetic fields, temperature gradients, etc. Insane. www.nature.com/articles/s41...

Following up: searching for the distribution of estrogen receptors in the brain, I realized the Allen Brain Atlas is male only. How is it possible that something this fundamental is still missing?

It's 2025, and there's apparently no female mouse atlas. Please, tell me I'm wrong.

Elevator ride is an underrated team building activity

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

New workshop! Just before SFN, join the Flatiron Institute Center for Computational Neuroscience of the Simons Foundation for a workshop on pynapple and NeMoS. Learn how to use these open-source packages to analyze and model neural data! Accommodation & meals provided. Link ⬇️

For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more #neuroskyence #academicsky

The point is now to make it middle school knowledge.

Sunday fun fact: A 3rd-century BC Roman coin depicting a hippocampus — the mythical sea creature linked to Neptune. One of 13,000 coins discovered while digging in the basement of a house in southern France, near the Pyrenees.

🚨 Preprint alert 🚨 The main results of my PhD are online and I only now could find some time to post about it! We explored the neurovascular activations of spatial navigation by using functional ultrasound imaging (fUSI) in freely moving rats during open field.

All the top arguments against the lab-leak theory of COVID-19, in a single email

« History shows that increasing wealth inequality consistently precedes collapse from the Classical Lowland Maya to the Han dynasty in China and the Western Roman empire » Nothing new, perhaps, but always worth repeating.

Fascinating Sunday read: some forms of untreatable schizophrenia may actually be misdiagnosed and curable. www.newyorker.com/magazine/202...

Trying to train RNNs in a biol plausible (local) way? Well, try our new method using predictive alignment. Paper just out in Nat. Com. Toshitake Asabuki deserves all the credit! www.nature.com/articles/s41...

Brenda Milner just turned 107. Happy birthday! On my very first day as a PI at the MNI, she was right in front of me in the cafeteria line. She was already nearly 100, and still coming to work. What a legend.

The thing about going on vacation with a multinational family… it always feels a bit like a spy movie.

This year, Canada Day feels extra special. It’s my first one as a Canadian citizen! 🇨🇦🎉

🧠🔬 This important study demonstrates that slow fluctuations in serotonin release during wakefulness and non-REM sleep correspond to periods of heightened arousal or enhanced offline information processing, especially in the hippocampus. Congrats to the authors! elifesciences.org/reviewed-pre...

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Out today in @nature.com: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables. www.nature.com/articles/s41...

Feeling proud 🥹 Dan is starting his lab at Yale, and I couldn’t be happier for him. A brilliant scientist, and a fantastic person to work with. I’m not expecting anything less than amazing from him. Congratulations, Dan!

Take some time and fill in this survey, it's fun!!

🚨🚨Job Alert🚨🚨!! Neuroscience, Physiology and Pharmacology are recruiting a new lecturer/associate professor! an amazing opportunity to join our fantastic dept! @ucl.ac.uk @ucllifesciences.bsky.social @uclnpp.bsky.social post here: www.nature.com/naturecareer...

For the first time in a looooong while, I wasn’t overwhelmed with work today. So I picked a fight at random, just like the good old days. And in the end, it all turned into love and laughter 💙🫶🏻

Who wants to be my new chair? mcgill.wd3.myworkdayjobs.com/en-US/McGill...

Quebec’s universities are calling for action to attract international research talent www.mcgill.ca/newsroom/cha...

Oh no, I love Dunbar’s number! (the idea that brain size correlates with social group size across primate species, leading to the famous estimate of 150 people for Homo sapiens.) I’ve told this story so many times…

Amazing study: @tamir-eliav.bsky.social from the Ulanovsky lab describes replay events in a large scale environment (200 m tunnel). 🦇 www.cell.com/cell/abstrac...

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

I went to the Justice concert last night. Whether or not you're into their music, the show is worth it for the light experience alone. At several moments, I felt like I was seeing colors I'd never seen before - a fantasy I’ve had for a long time: to one day create a color that doesn’t exist.

Curious to see how steep the drop in abstract submissions to SfN will be this year.

Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...

Congrats to the fantastic Jess P for her new paper! She compared how feature Vs outcome focussed agents learn to solve contextual inference problems. She found that you need a balance of both to learn these tasks - and that this mix recapitulates pfc and hippocampal activity in rodent tasks!

A nice new study of the lab showing that the auditory maintains a much more detailed short-term memory of the sound in the offset responses than subcortical regions of the auditory system. Next step would be to understand what are the neural dynamics underlying this.

🚨Very excited to share a new paper from our lab in Neuron (@cp-neuron.bsky.social) on the influence of the estrous cycle on structural and functional plasticity in the hippocampus: www.sciencedirect.com/science/arti... Thread below 🧠🧪🧵:

Canada joining the EU to build up its defense? Be bold. Broaden the vision. Make Canada part of Erasmus, ERC (it is already part of Horizon Europe), and so many other fantastic European programs.