No GPS in the head? Path integration by entorhinal grid cells without the grid pattern. Interesting paper from Heidelberg. www.nature.com/articles/s41...

Neuroscience projects last several years, and you are usually a bit jaded by the time you wrap it up. Not this one– spending several months on an island in the middle of nowhere, away from all the craziness of the world reminds you how beautiful the world really is. www.youtube.com/watch?v=46sv...

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇 kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

Thanks to the Capitainerie de l’Isle and to Nathalie for hosting our exhibit ✨

Travel awards are available for undergraduate students looking to attend #Cosyne25! The application is short, and the deadline is Nov 12. @cosynemeeting.bsky.social Application: shorturl.at/6NEyk More info: www.cosyne.org/travel-grants (1/2)

Dear #ParisNeuroscience community, here is the schedule of the upcoming 'Neural Networking Night' season !

2/6 Recording in decision-making regions from many neurons at once revealed the neurons' collective evolution as decisions were made Each decision had two phases: first, neural state was sensitive to sensory inputs; then, trajectories in neural state space turned and became insensitive to inputs.

How does the brain decide? 🧠 Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc. After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up. rdcu.be/eGUrv

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

Voir Montrer Regarder 👀 Observer Mesurer Vérifier #SciArt If you are in Paris in September check out our exhibit “Regards Croisés”: Come for the Art, stay for the Science ! This scientific outreach event is supported by @c-brains.bsky.social, @sppin-cnrs.bsky.social and the Capitainerie de l’Isle.

*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11

Happy to share our new paper with Mathilde Nordlund and Julie Koenig out @currentbiology.bsky.social. We used virtual reality in mice to study hippocampal distance coding. Our results suggest a primary contribution of grid cells to distance over cue-dependent place cell coding. shorturl.at/63yFo

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

And the Valero / Buzsaki paper: www.science.org/doi/10.1126/...

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

The main project from my PhD, in collaboration with Manuela Allegra and @schlab.bsky.social is now available as a preprint! We wondered how the hippocampus and the visual cortex may differ in the way they refine sensory inputs into internal representations

🎨🔬 Quand l’art rencontre la science ! Le SPPIN est heureux de vous annoncer l'Expo #SciArt “Regards Croisés” avec l’artiste Sophie Sainte-Marie-Heim et notre collègue @desdemonafricker.bsky.social 🗓 22–28 sept. 2025 📍 Capitainerie de l’Isle, 26 rue Chanoinesse, Paris 4e Venez nombreux !

🚨PhD student position in #cognitive_psychology and #neuroscience, on a project directed by André Knops and in collaboration with the Dugué Lab! @upcite.bsky.social | @cnrs.fr Funded by the @agencerecherche.bsky.social (Agence nationale de la recherche) www.linkedin.com/jobs/view/42...

📣 We are expanding! Repost 🙏🏽 - Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping) - Project Associates - Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗) www.neuroact.in

Remote activation of place codes by gaze in a highly visual animal www.nature.com/articles/s41... - very cool study with chickadees!

Voir Montrer Regarder 👀 Observer Mesurer Vérifier #SciArt If you are in Paris in September check out our exhibit “Regards Croisés”: Come for the Art, stay for the Science ! This scientific outreach event is supported by @c-brains.bsky.social, @sppin-cnrs.bsky.social and the Capitainerie de l’Isle.

1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪

New work! Learning is assumed to involve synaptic plasticity, but which specific synapses change to enable higher order cognitive functions? We actually find that cognitive flexibility involves potentiation of long-range GABAergic synapses from prefrontal PV neurons: www.biorxiv.org/content/10.1...

Great wave of @agencerecherche.bsky.social results for SPPIN ! Congrats to our researchers & their amazing partners! @desdemonafricker.bsky.social : HDNavigGO @npanayotis.bsky.social : ReGeNeRETT G. Caron: MNIONALS (JCJC) @brandonstell.bsky.social : AdaptingMovement @cnrs.fr @upcite.bsky.social

Our study is out in Nature! Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models. 👉 www.nature.com/articles/s41...

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

🚶Aimlessly wandering around a city or exploring the new mall may seem unproductive, but new research led by @zh0ng0.bsky.social @marius10p.bsky.social @computingnature.bsky.social suggests it could play an important role in how our brains learn.‬‬ 🧠 🔗 www.janelia.org/news/zoning-...

🚀 We are excited to share that bombcell is now available in Python! 🐍 Automatically sort your units into good/MUA/noise/non-somatic using quality metrics and interpretable & adjustable classification thresholds. pip install and play around with our toy dataset: 🔗 github.com/Julie-Fabre/...

I really recommend sending your students to the Paris Spring School, many imaging and ephys techniques are covered in pretty good depth and the atmosphere is consistently fantastic every year! And in such a setting! parisneuro.ovh

Running Paris Spring School practicals this week! The fabulous @maxime-beau.bsky.social is teaching the ins and outs of Neuropixels recordings, with help from the brilliant Marin Dauguet and all the team. @upcite.bsky.social @sppin-cnrs.bsky.social #neuroscience 👩‍🔬🧠 parisneuro.ovh

I am at #NeuroFrance2025 in Montpellier 🇫🇷🥖🥳 Getting excited about our symposium on #Coordinating #vision, #orientation, and #navigation 👁️🧭🐾 with: @gbouvier.bsky.social @sepikeshavarzi.bsky.social @mayankmehta.bsky.social @socneuro.bsky.social #neuroscience 🧠

New preprint out in eLife! Neurons in medical entorhinal cortex (MEC) develop responses to visual cues and reward as mice learn a visual Go/NoGo task. elifesciences.org/reviewed-pre...

Mark you calendar! We will host Stephanie Rudolph from @einsteinmededu.bsky.social for her talk: "A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks" 📍 SPPIN Seminar Room 📅 June 10th ⏰ 11 AM Join us @sppin-cnrs.bsky.social !

GABAergic neurons are major contributors of network inhibition in the neonatal hippocampus in-vivo https://www.biorxiv.org/content/10.1101/2025.04.26.650764v1

Postdoctoral opening in my lab thanks to @erc.europa.eu SyG Chronology w/ wonderful @bathellierlab.bsky.social S. Ostojic & M. Jazayeri Interested in characterizing temporal cognitive maps in the human brain? 👇 brainthemind.com/wp-content/u... @unicog.bsky.social @cea-joliot.bsky.social

OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word www.nature.com/naturecareer...

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social #KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com @kavlifoundation.bsky.social www.nature.com/articles/s41...

🚨New article from the #DuguéLab in #PLOS_Computational_Biology, led by @lgrabot.bsky.social! We developed a new model-based neuroimaging approach to study Traveling Waves in visual cortex using MEG-EEG. @erc.europa.eu journals.plos.org/ploscompbiol...

My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour. Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org

Excited to share the sequel to our 2022 paper! In this follow-up, we show that the stable head direction (HD) signals we reported in blind mice rely on stereo olfaction—that is, the comparison of odor info. between the two nostrils. Link: www.nature.com/articles/s41... 🧵highlights below

Firing rates in visual cortex show representational drift, while temporal spike sequences remain stable www.sciencedirect.com/science/arti... Great work by Boris Sotomayor and with @battaglialab.bsky.social

I'm pleased to announce that the Version of Record of our eLife paper, "Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice" (Vickers and McCormick, 2024) is now available at: elifesciences.org/articles/94167 (94167.3, VOR).

go.bsky.app/LdtUYZS I created a starter pack for the growing community of hippocampus physiologists that have joined the great migration. Also included the physiology-adjacent. Tell me who I haven’t found yet

The team leaders of the @sppin-cnrs.bsky.social express their concern as to the developments affecting science & scientists in the USA.

My lab University College London is looking for an experimental postdoc to join our team. Interested in circuits underlying visually guided behavior, chronic #Neuropixel recordings or 2-photon imaging (Benchtop, #Mini2p)? Then check out our lab homepage www.ruedigerlab.com, apply & spread the word

#NeuroFrance2025 registration & abstract submission are open! 🥳 We'll be back in the beautiful city of Montpellier next May for the biggest neuroscience meeting in France. Don't miss out! 🤩 Registration: www.neurosciences.asso.fr/SN25/inscrip...

How does the brain work in natural scenarios, in multi-animal societies of wild animals? 🧠 🧪 🦇 doi.org/10.1126/scie... (1/n)