New manuscript from the lab! "Mirror manifolds: partially overlapping neural subspaces for speaking and listening" Led by superstar grad student Anilu Chavez (not on Bluesky)! www.biorxiv.org/content/10.1...

🛑 Attention researchers who train freely-moving rodents! Jess Breda and I developed a protocol for training center-port nose fixation 61% faster than a previous curriculum while keeping violation rates low. Preprint here: www.biorxiv.org/content/10.1...

Our cognitive maps of the environment contain hierarchical structure, with some spaces nested in others. Behavioral responses and brain activity in scene-responsive regions reflect this hierarchical structure. Neat new work by Michael Peer & @russellepstein.bsky.social! doi.org/10.1093/cerc...

How does the brain decide? 🧠 Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc. After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up. rdcu.be/eGUrv

Thanks @thetransmitter.bsky.social & @franciscorr25.bsky.social for featuring my lab in the "Liftoff" series!

1/ 🚨 New preprint! 🚨 Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇 📄 www.biorxiv.org/content/10.1... 💻 code + data 🔗 below 🤩 #neuroskyence

I found this paper very boring* Effort and Boredom Shape our Experience of Time *No I didn't. And, surprise! They propose the insula as a link between boredom and perceived duration www.sciencedirect.com/science/arti...

*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

New very cool work from the Yaksi lab: Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain www.biorxiv.org/content/10.1...

How do we update our predictions when our environment changes? The hippocampus rapidly integrates previously distinct sequences to support updated predictions. Proud of this work with Hannah Tarder-Stoll & @chrisbaldassano.bsky.social! www.biorxiv.org/content/10.1...

For those interested in open neuroscience learning tools, check out the preprint for “RetINaBox: A hands-on tool for experimental neuroscience" that a couple students in my lab worked on in collaboration with the Trenholm lab: www.biorxiv.org/content/10.1... 🧠📈 🧪

"Sleep, like aging, may be an inescapable consequence of aerobic metabolism." Really enjoyed this thought-provoking paper 🧠💤🪰 - congrats to @rafsarnataro.bsky.social and team on this impressive work! No wonder the Krebs cycle always put me to sleep 😅 #neuroskyence

(1/8) New paper from our team! Yu Duan & Hamza Chaudhry introduce POCO, a tool for predicting brain activity at the cellular & network level during spontaneous behavior. Find out how we built POCO & how it changes neurobehavioral research 👇 arxiv.org/abs/2506.14957

Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

Nice field study on ultrasound communication in African striped mice identifies group-specific calls that encode social identity and differ depending on the site of emission, i.e., at nest, in territory or at its border. @currentbiology.bsky.social www.sciencedirect.com/science/arti...

𝗕𝗿𝗮𝗶𝗻-𝘄𝗶𝗱𝗲 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 Spatially distributed and regionally unbound cellular resolution brain-wide processing loops in mice 𝗕𝗿𝗮𝗶𝗻 𝗿𝗲𝗴𝗶𝗼𝗻𝘀 𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰 𝘁𝗵𝗿𝗲𝗮𝗱𝘀? Dynamical processing winding through most brain regions. Looks like a must read. www.biorxiv.org/content/10.1... #neuroskyence

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

Hi Cian, I think this is the result of systematic statistical bias in sample AC: the shape of sample AC is negatively biased as time series become shorter (the bias can be computed analytically for simple processes). We discuss this in detail here: www.nature.com/articles/s43...

Good morning everyone! So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory* www.amazon.com/How-Change-M...

🚀Excited to share our project: Canonical Representational Mapping for Cognitive Neuroscience. @schottdorflab.bsky.social and I propose a novel multivariate method to isolate neural representations aligned with specific cognitive hypotheses 🧵https://www.biorxiv.org/content/10.1101/2025.09.01.673485v1

Oh man, I am so excited and happy to have been given this huge opportunity by the @erc.europa.eu It is by no exaggeration - a dream come true. An insufficient thank you thread (1/4)

Great to have another paper with @chazfirestone.bsky.social @ianbphillips.bsky.social and the brilliant Hanbei Zhou out! In this paper we demonstrate that stimuli within events are perceived further apart in time — an event-based analog of “object-based warping”. psycnet.apa.org/record/2026-...

How do the brain’s event representations change as we gain familiarity with an experience? Brain regions’ representations can become coarser or finer as event familiarity increases. Fine-tuning predicts memory recall. Excited to share this work with Narjes Al-Zahli & @chrisbaldassano.bsky.social!

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

🚨 New preprint! 🚨 Proud to have been a small part of this project RatDISCO is a simple & affordable tissue-clearing protocol that works in rodent brains and organoids. Enormous potential for imaging long-range projections and labelled neuron populations in the whole brain 🧠 👉 tinyurl.com/670723v1

We make predictions based on general knowledge and/or specific memories. Different brain areas are active when these distinct predictions are violated – and hippocampus selectively responds to prediction errors based on episodic memory. Cool work by @chrismbird.bsky.social @ayab.bsky.social et al!

ATTN🚨: I will be looking for PhD students through NYU's Center for Data Science PhD program this year. Applicants should have an interest in either NeuroAI (specifically biological attention or AI interpretability) or ML for Remote Sensing. Visit my lab website for more info: lindsay-lab.github.io

Fresh results now in bioRxiv! 🎉 We know about the function of NREM sleep for overnight memory consolidation. But what about REM sleep? We found that in aging, slow delta waves can intrude phasic REM periods, and this, is associated with worse overnight consolidation 🧠 (1/5) doi.org/10.1101/2025...

New publication from my lab: Vampyrum spectrum, the Neotropics' largest carnivorous bat, is very cooperative. These gentle apex predators regularly provide prey for family member – documented in the wild for the first time. doi.org/10.1371/jour...

I wrote a Comment on neurotheory, and now you can read it! Some thoughts on where neurotheory has and has not taken root within the neuroscience community, how it has shaped those subfields, and where we theorists might look next for fresh adventures. www.nature.com/articles/s41...

I just read this amazing paper. Many provocative findings here.

Running hot and cold... Preoptic EP3R neurons constitute a two-way switch for fever and torpor www.nature.com/articles/s41...

No one ever steps in the same movie twice. Anticipatory gaze 👁️ indicate episodic memory seconds before an event occurs. 🧠🐾 Very robust effects across both natural and crafted movies, and of course, after sleep! 😴. Out today in Communication Psychology: www.nature.com/articles/s44... Check it out!

🚨 I’m excited to say that my CIHR Project Grant was funded! My NHP lab is now full-speed-ahead, and I’m hiring experimentalists (postdoc, PhD student, and/or a tech/manager). We’ll do multi-region ephys during reaching/grasping in macaques, with behavioral and spinal perturbations.

Excited to announce that my first postdoc paper is now online! Links: www.nature.com/articles/s41... rdcu.be/eAcN7 In it, we examine the perennial question: what changes in the brain when learning a new motor skill? Read more below to find out 👇

Preprint⭐ Our attention changes over time and differs across contexts—which is reflected in the brain🧠 Fitting a dynamical systems model to fMRI data, we find that the geometry of neural dynamics along the attractor landscape reflects such changes in attention! www.biorxiv.org/content/10.1...

Hey, as a librarian I need to tell you: Our funding depends on usage. So go ahead and check out that book even if you don't think you'll finish it. No one will know. Check out that DVD even though you might not like it. Get ambitious in your quest for knowledge.

My latest column for @thetransmitter.bsky.social - why neural populations are a convenient fiction doi.org/10.53053/FZK...

We have an emerging cicada at moth night!!

I appreciate this thoughtful obit for Masashi Kawaski, written by his friend and collaborator Günther Zupanc. Like everyone who knew or worked with Masashi, I was impressed with his deep kindness and great sense of humor. #neuroethology link.springer.com/article/10.1...

Check out our first study on New York City rats, the preprint is here : www.biorxiv.org/content/10.1...

After you fall asleep in the sleep lab, we can decide what you dream about — as Karen Konkoly showed in her PhD work and just published in this new paper: “Investigating dreams by strategically presenting sounds during REM sleep to reactivate waking experiences” authors.elsevier.com/c/1lWFU6TBG5...

late to share, but still exciting 🤩 our latest paper is now published tinyurl.com/2s4zecr9 ✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling 👏 great work team @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social

A new study by Forli, Fan, Qi & Yartsev 2025 shows that wingbeat cycle in bats is #rhythmic at 8Hz ❗❗& like the #rat #stepping, internal hippocampal representations can synchronize with the wingbeat phase. ➡️ Bat wingbeat www.nature.com/articles/s41... ➡️ Rat steps www.nature.com/articles/s41... 🦇🐀👀

New paper with @mujianing.bsky.social & @prestonlab.bsky.social! We propose a simple model for human memory of narratives: we uniformly sample incoming information at a constant rate. This explains behavioral data much better than variable-rate sampling triggered by event segmentation or surprisal.

“Deep in the Peruvian Amazon, a spider is at work building an elaborate, fake decoy of itself. In its web, it busily goes to working crafting its doppelgänger out of leaves, debris and dead prey insects…” #scicomm #sensoryecology #falsesignal www.smithsonianmag.com/smart-news/s... 🧪 🕷️

🚨Very happy that my PhD work is now out in @nature.com! We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments www.nature.com/articles/s41... This was a truly collaborative effort! 🧵⬇️

Fantastic to see this collaborative work with Hopi Hoekstra out in Nature (tinyurl.com/3at3zvby). Lead by @felixbaier.bsky.social and @katjareinhard.bsky.social. Not possible without @bramnuttin.bsky.social , Chen Liu and @arnausd.bsky.social. Excited to see where this work leads.