Matt Perich
@mattperich.bsky.social
📤 1597
📥 174
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Neuroscience, engineering, AI, music. Asst. Professor / PI at University of Montréal and Mila.
pinned post!
Check out our new paper led by
@oliviercodol.bsky.social
! We use RNNs to explore possible learning rules that lead to the dynamics we see in brains during behavior.
www.biorxiv.org/content/10.1...
#neuroskyence
#compneurosky
#neuroai
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12 months ago
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Matt Perich
14 days ago
Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...
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Motor cortex flexibly deploys a high-dimensional repertoire of subskills
Skilled movement often requires flexibly combining multiple subskills, each requiring dedicated control strategies and underlying computations. How the motor system achieves such versatility remains u...
https://www.biorxiv.org/content/10.1101/2025.09.07.674717v1
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🚨 I’m excited to say that my CIHR Project Grant was funded! My NHP lab is now full-speed-ahead, and I’m hiring experimentalists (postdoc, PhD student, and/or a tech/manager). We’ll do multi-region ephys during reaching/grasping in macaques, with behavioral and spinal perturbations.
about 1 month ago
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Awesome work from
@juangallego.bsky.social
and lab. An interface from single motoneuron control in tetraplegia!
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about 2 months ago
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Matt Perich
Kanaka Rajan
about 2 months ago
Check out
@jordancollver.bsky.social
’s great illustration of modular RNNs training to work like a bio-brain🦾🧠 Thanks to Crearte for featuring our collaboration!
www.instagram.com/crearte.ca/p...
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The Crearte Foundation | #ArtScience on Instagram: "When a neurobiologist is also a comic artist, science can have a whole new storyline. In a 2022 collaboration between the Rajan Lab at Harvard Med...
6 likes, 0 comments - crearte.ca on July 28, 2025: "When a neurobiologist is also a comic artist, science can have a whole new storyline. In a 2022 collaboration between the Rajan Lab at Harvard Med...
https://www.instagram.com/crearte.ca/p/DMp5A1SRnki/
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reposted by
Matt Perich
Juan Gallego
about 2 months ago
Very happy about my former mentor Sara Solla having received the Valentin Braitenberg Award for her lifelong contributions to computational neuroscience! Sara will be giving a lecture at the upcoming
@bernsteinneuro.bsky.social
meeting which you shouldn't miss.
bernstein-network.de/en/newsroom/...
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Sara A. Solla receives the Valentin Braitenberg Award for Computational Neuroscience 2025 – Bernstein Network Computational Neuroscience
https://bernstein-network.de/en/newsroom/news/sara-solla-receives-valentin-braitenberg-award-2025/
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📰 I really enjoyed writing this article with
@thetransmitter.bsky.social
! In it, I summarize parts of our recent perspective article on neural manifolds (
www.nature.com/articles/s41...
), with a focus on highlighting just a few cool insights into the brain we've already seen at the population level.
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about 2 months ago
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reposted by
Matt Perich
Juan Gallego
about 2 months ago
🚨New paper🚨 Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently. Here, we clarify our take on the term, and review key findings & challenges
rdcu.be/ex8hW
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reposted by
Matt Perich
Mark Histed
about 2 months ago
'manifolds', and the overall conception of the brain using a dynamical systems framework, have come a long way.
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Check out our new review/perspective (w/
@juangallego.bsky.social
& Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗:
www.nature.com/articles/s41...
📄:
rdcu.be/ex8hW
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A neural manifold view of the brain - Nature Neuroscience
Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...
https://www.nature.com/articles/s41593-025-02031-z
about 2 months ago
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reposted by
Matt Perich
3 months ago
Finally out! Eight years after initiating this study with Simon Borgognon, Nicolo Macellari, and Gregoire Courtine, we have uncovered neural population dynamics shared among premotor, motor, and somatosensory cortices during various types of locomotor tasks.
www.nature.com/articles/s41...
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Regional specialization of movement encoding across the primate sensorimotor cortex - Nature Communications
How the cortex generates movement to achieve different tasks remains poorly understood. Here the authors show that the cortex serializes motor control by first performing task-specific computations in...
https://www.nature.com/articles/s41467-025-61172-8
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Our new approach for scalable, generalizable, and efficient neural population decoding is now online! Here we focus on real-time BCI but I'm excited about all of our next steps building on this. Awesome work led by
@averyryoo.bsky.social
@nandahkrishna.bsky.social
@ximengmao.bsky.social
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3 months ago
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Matt Perich
Avery HW Ryoo
6 months ago
Very late, but had a 🔥 time at my first Cosyne presenting my work with
@nandahkrishna.bsky.social
, Ximeng Mao,
@mattperich.bsky.social
, and
@glajoie.bsky.social
on real-time neural decoding with hybrid SSMs. Keep an eye out for a preprint (hopefully) soon 👀
#Cosyne2025
@cosynemeeting.bsky.social
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Matt Perich
The Transmitter
6 months ago
Many apparent disagreements over the utility of neural manifolds come from a lack of clarity on what the term really encompasses, argues
@mattperich.bsky.social
#neuroskyence
www.thetransmitter.org/neural-dynam...
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Neural manifolds: Latest buzzword or pathway to understand the brain?
When you cut away the misconceptions, neural manifolds present a conceptually appropriate level at which systems neuroscientists can study the brain.
https://www.thetransmitter.org/neural-dynamics/neural-manifolds-latest-buzzword-or-pathway-to-understand-the-brain/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250330-cosyne-neural-manifolds
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reposted by
Matt Perich
Martin Seeber
7 months ago
🧠 Our new (NIH funded!) paper reveals how the brain creates internal dynamics during both real- and imagined navigation. We recorded directly from the human hippocampus as participants moved through physical space and when they mentally navigated imagined routes.
www.nature.com/articles/s41...
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Human neural dynamics of real-world and imagined navigation - Nature Human Behaviour
Seeber et al. studied brain recordings from implanted electrodes in freely moving humans. Neural dynamics encoded actual and imagined routes similarly, demonstrating parallels between navigational, im...
https://www.nature.com/articles/s41562-025-02119-3
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reposted by
Matt Perich
Claudia Clopath Lab
7 months ago
Want to hear more about how feedback can guide learning in RNNs for motor adaptation. Here is our new paper in Nat. Com. with Barbara Feulner and
@juangallego.bsky.social
www.nature.com/articles/s41...
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A neural implementation model of feedback-based motor learning - Nature Communications
How the brain adapts our movements to new conditions remains unclear. Here, the authors show that a recurrent neural network that controls its output using error-based feedback can learn to count...
https://www.nature.com/articles/s41467-024-54738-5
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reposted by
Matt Perich
Josh Dudman
8 months ago
Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now.
www.cell.com/neuron/fullt...
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Conjoint specification of action by neocortex and striatum
Park et al. show that motor cortex and subcortical striatum act in concert to specify the movement parameters of a reach-to-pull action in mice.
https://www.cell.com/neuron/fulltext/S0896-6273(24)00922-X?rss=yes
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Great initiative! The Transmitter is awesome.
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9 months ago
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Matt Perich
Blake Richards
9 months ago
1/ Okay, one thing that has been revealed to me from the replies to this is that many people don't know (or refuse to recognize) the following fact: The unts in ANN are actually not a terrible approximation of how real neurons work! A tiny 🧵. 🧠📈
#NeuroAI
#MLSky
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Well said! Great colleagues make this job fun, and I couldn't imagine a better group of them. Thanks for a great 2024, and looking forward to more science in 2025!
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9 months ago
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Matt Perich
Amy Orsborn
10 months ago
Fun to see this place coming a bit more alive! I tried my hand at a starter pack for neural engineering & computationally-leaning (systems) neuroscience. Super not exhaustive, so if you want to be added (or removed), just ping me. I'm still working on finding folks here.
go.bsky.app/Ty3ftme
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reposted by
Matt Perich
Zach Zeisler
11 months ago
We have a new paper on bioRxiv today!
www.biorxiv.org/content/10.1...
Quick thread summary over on Twitter:
x.com/ZachZeisler1...
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Consistent hierarchies of single-neuron timescales in mice, macaques and humans
The intrinsic timescales of single neurons are thought to be hierarchically organized across the cortex. This conclusion, however, is primarily based on analyses of neural responses from macaques. Whe...
https://www.biorxiv.org/content/10.1101/2024.10.30.621133v1
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Matt Perich
Jonathan A. Michaels
11 months ago
How can we train a BCI to produce precise hand movements? Our paper published today in Neuron provides one possibility! We show that the abundant hand posture-related information in the grasping circuit can be used for precise grasp control.
www.cell.com/neuron/abstr...
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Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit
Hand posture is amply represented in the cortex, but brain-computer interfaces (BCIs) have not fully leveraged this signal. Agudelo-Toro et al. developed a method allowing subjects to control a virtua...
https://www.cell.com/neuron/abstract/S0896-6273(24)00688-3
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Matt Perich
Guillaume Lajoie
11 months ago
How continuous neural activity learns and support discrete, symbolic & compositional processes remains an important question for cog. sci. and AI. In this preprint we explore ways in which both symbolic and sub-symbolic processing could be achieved using attractor dynamics.
arxiv.org/abs/2310.01807
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Discrete, compositional, and symbolic representations through attractor dynamics
Symbolic systems are powerful frameworks for modeling cognitive processes as they encapsulate the rules and relationships fundamental to many aspects of human reasoning and behavior. Central to these ...
https://arxiv.org/abs/2310.01807
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Check out our new paper led by
@oliviercodol.bsky.social
! We use RNNs to explore possible learning rules that lead to the dynamics we see in brains during behavior.
www.biorxiv.org/content/10.1...
#neuroskyence
#compneurosky
#neuroai
add a skeleton here at some point
12 months ago
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Who needs more neural manifolds? In my opinion: everyone! This was a fun article to write, thanks to
@thetransmitter.bsky.social
and
@emilytransmitter.bsky.social
for making it happen!
#neuroskyence
#compneurosky
#neuroAI
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12 months ago
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reposted by
Matt Perich
Aaron Batista
about 1 year ago
When you fail to perform at your best right when it matters the most, what's going on in your brain? We can now provide an explanation: Exceptionally high stakes interfere with the neural signals of motor preparation. I'd love to hear - what do you think causes it?
sciencedirect.com/science/arti...
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A neural basis of choking under pressure
Incentives tend to drive improvements in performance. But when incentives get too high, we can “choke under pressure” and underperform right when it m…
https://sciencedirect.com/science/article/pii/S0896627324006081?dgcid=author
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reposted by
Matt Perich
Guillaume Lajoie
about 1 year ago
The call for
#Cosyne25
workshop proposals is now live!
cosyne.org/workshops-call
Deadline: October 4th, 2024 please repost!
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Call For Proposals — COSYNE
https://cosyne.org/workshops-call
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Matt Perich
Grace Lindsay
about 1 year ago
Important info on the state of nonhuman primate research in the US. This is such a core part of neuroscience work.
www.jneurosci.org/content/44/3...
#neuroskyence
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The Future of Nonhuman Primate Neuroscience: Peril or Possibilities?
COVID-19 and polio vaccines, HIV/AIDS treatments, blood transfusions, and organ transplantation are just a few of the medical advances made possible by research involving nonhuman primates, specifical...
https://www.jneurosci.org/content/44/37/e1458242024
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Matt Perich
Juan Gallego
about 1 year ago
Just created a list with the sensorimotor people I was following/followed me (inclusion criteria slightly generous) Let me know if you want to be added, and repost (?) to spread the word
go.bsky.app/U4oyFgw
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Matt Perich
Olivier Codol
over 1 year ago
The latest MotorNet release (v0.2.0) is live! This includes big changes, first and foremost, a COMPLETE SWAP from TensorFlow to PyTorch. As usual, you can install it via a pip command.
motornet.org
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MotorNet 0.2.0 documentationContentsMenuExpandLight modeDark modeAuto light/dark mode
https://motornet.org
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reposted by
Matt Perich
JJ
almost 2 years ago
Here is a list of people doing sensorimotor research and that have a BlueSky account:
bsky.app/profile/did:...
Too bad most of them are barely active here but this shows that there is potential….
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New paper out this week in Nature!
nature.com/articles/s41...
Many thanks to the co-authors for making this happen, especially co-senior / best friend
@juangallego.bsky.social
, and co-leads Mostafa + Joanna! I also want to say a word about the translational implications 👇
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Preserved neural dynamics across animals performing similar behaviour - Nature
Recordings of neural populations from motor cortex and striatum spanning monkeys and mice demonstrate that neural dynamics in individuals from the same species are preserved when they perform sim...
https://nature.com/articles/s41586-023-06714-0
almost 2 years ago
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Matt Perich
Benjy Barnett
almost 2 years ago
Seems apt that this huge leap forward in decoding methods would come out just a day before this thought-provoking piece on decoding, zombies, and consciousness!
#neuroskyence
#consciousness
onlinelibrary.wiley.com/doi/10.1111/...
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Awesome work led by
@mehdiazabou.bsky.social
and
@evadyer.bsky.social
towards unifying large scale datasets into a single model. The real gem here is the spike tokenization, super clever way to solve a key problem. Check it out!
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almost 2 years ago
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