Some of you saw a preview of this result at my Cosyne talk last week. We may have had too much fun working on this worm-fly model 🤣🤓🤣 (The digital sphinx may be imagery, but the lessons are real.)

Here's a lovely #blueprint on a new study from our lab led by @royeyono.bsky.social. tl;dr: it implies that there may be interneurons whose role is to normalize credit assignment signals during learning. #neuroscience 🧪

New paper! We introduce JEDI, Jointly Embedded Dynamics Inference for neural dynamics. arxiv.org/abs/2603.10489. JEDI flexibly infers dynamical principles (across behaviors/contexts) from neural population data through RNNs constrained at single-neuron resolution to reproduce that data.

New paper hot off the (pre-)press! We dig into the evolutionary origins of neural computations for behavioral control across mice, monkeys, and humans: www.biorxiv.org/content/10.6.... As our lab's first foray into comparative analysis of neural dynamics, I’m super excited about this work! 1/18

1. I’m quite happy with this popular piece that Lee Dugatkin and I wrote recently. For the next two weeks it’s free to read on the American Scientist website.

Our paper is out in Science Advances! What makes primate hands so dexterous? We show that evolutionarily distinct spinal and cortical pathways work together to balance stability and flexibility, supporting remarkable primate hand control. www.science.org/doi/10.1126/...

Beautiful to see! Great work!

🚨📜+🧵🚨 Very excited about this work showing that people with no hand function following a spinal cord injury can control the activity of motor units from those muscles to perform 1D, 2D and 3D tasks, play video games, or navigate a virtual wheelchair By a wonderful team co-mentored w Dario Farina

Go work with Juan! I can vouch that this will be a very cool project.

🚨Job alert🚨 The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour This is part of a collaborative ARIA grant "4D precision control of cortical dynamics" euraxess.ec.europa.eu/jobs/383909

If you're interested in dynamical systems analysis for neuroscience, definitely check out @oliviercodol.bsky.social 's revised version of our RL paper! Very cool results in the new Fig 6, worth it regardless of if you saw our previous version or if it's all new. www.biorxiv.org/content/10.1...

A big "get" for the Champalimaud! Excited to see what comes out of the Warehouse and the next phase of Juan's lab

Very excited and proud to share my postdoctoral research with @neurrriot.bsky.social looking at the context-specific encoding of social behavior 💃🕺 in hormone-sensitive, large-scale brain networks in mice! www.biorxiv.org/content/10.1... #neuroskyence #compneurosky 🧪 1/12

Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric. www.biorxiv.org/content/10.1...

🚨 I’m excited to say that my CIHR Project Grant was funded! My NHP lab is now full-speed-ahead, and I’m hiring experimentalists (postdoc, PhD student, and/or a tech/manager). We’ll do multi-region ephys during reaching/grasping in macaques, with behavioral and spinal perturbations.

Awesome work from @juangallego.bsky.social and lab. An interface from single motoneuron control in tetraplegia!

Check out @jordancollver.bsky.social’s‬ great illustration of modular RNNs training to work like a bio-brain🦾🧠 Thanks to Crearte for featuring our collaboration! www.instagram.com/crearte.ca/p...

Very happy about my former mentor Sara Solla having received the Valentin Braitenberg Award for her lifelong contributions to computational neuroscience! Sara will be giving a lecture at the upcoming @bernsteinneuro.bsky.social meeting which you shouldn't miss. bernstein-network.de/en/newsroom/...

📰 I really enjoyed writing this article with @thetransmitter.bsky.social! In it, I summarize parts of our recent perspective article on neural manifolds (www.nature.com/articles/s41...), with a focus on highlighting just a few cool insights into the brain we've already seen at the population level.

🚨New paper🚨 Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently. Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW

'manifolds', and the overall conception of the brain using a dynamical systems framework, have come a long way.

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

Finally out! Eight years after initiating this study with Simon Borgognon, Nicolo Macellari, and Gregoire Courtine, we have uncovered neural population dynamics shared among premotor, motor, and somatosensory cortices during various types of locomotor tasks. www.nature.com/articles/s41...

Our new approach for scalable, generalizable, and efficient neural population decoding is now online! Here we focus on real-time BCI but I'm excited about all of our next steps building on this. Awesome work led by @averyryoo.bsky.social @nandahkrishna.bsky.social @ximengmao.bsky.social

Very late, but had a 🔥 time at my first Cosyne presenting my work with @nandahkrishna.bsky.social, Ximeng Mao, @mattperich.bsky.social, and @glajoie.bsky.social on real-time neural decoding with hybrid SSMs. Keep an eye out for a preprint (hopefully) soon 👀 #Cosyne2025 @cosynemeeting.bsky.social

Many apparent disagreements over the utility of neural manifolds come from a lack of clarity on what the term really encompasses, argues @mattperich.bsky.social #neuroskyence www.thetransmitter.org/neural-dynam...

🧠 Our new (NIH funded!) paper reveals how the brain creates internal dynamics during both real- and imagined navigation. We recorded directly from the human hippocampus as participants moved through physical space and when they mentally navigated imagined routes. www.nature.com/articles/s41...

Want to hear more about how feedback can guide learning in RNNs for motor adaptation. Here is our new paper in Nat. Com. with Barbara Feulner and @juangallego.bsky.social www.nature.com/articles/s41...

Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now. www.cell.com/neuron/fullt...

Great initiative! The Transmitter is awesome.

1/ Okay, one thing that has been revealed to me from the replies to this is that many people don't know (or refuse to recognize) the following fact: The unts in ANN are actually not a terrible approximation of how real neurons work! A tiny 🧵. 🧠📈 #NeuroAI #MLSky

Well said! Great colleagues make this job fun, and I couldn't imagine a better group of them. Thanks for a great 2024, and looking forward to more science in 2025!

Fun to see this place coming a bit more alive! I tried my hand at a starter pack for neural engineering & computationally-leaning (systems) neuroscience. Super not exhaustive, so if you want to be added (or removed), just ping me. I'm still working on finding folks here. go.bsky.app/Ty3ftme

We have a new paper on bioRxiv today! www.biorxiv.org/content/10.1... Quick thread summary over on Twitter: x.com/ZachZeisler1...

How can we train a BCI to produce precise hand movements? Our paper published today in Neuron provides one possibility! We show that the abundant hand posture-related information in the grasping circuit can be used for precise grasp control. www.cell.com/neuron/abstr...

How continuous neural activity learns and support discrete, symbolic & compositional processes remains an important question for cog. sci. and AI. In this preprint we explore ways in which both symbolic and sub-symbolic processing could be achieved using attractor dynamics. arxiv.org/abs/2310.01807

Check out our new paper led by @oliviercodol.bsky.social ! We use RNNs to explore possible learning rules that lead to the dynamics we see in brains during behavior. www.biorxiv.org/content/10.1... #neuroskyence #compneurosky #neuroai

Who needs more neural manifolds? In my opinion: everyone! This was a fun article to write, thanks to @thetransmitter.bsky.social and @emilytransmitter.bsky.social for making it happen! #neuroskyence #compneurosky #neuroAI

When you fail to perform at your best right when it matters the most, what's going on in your brain? We can now provide an explanation: Exceptionally high stakes interfere with the neural signals of motor preparation. I'd love to hear - what do you think causes it? sciencedirect.com/science/arti...

The call for #Cosyne25 workshop proposals is now live! cosyne.org/workshops-call Deadline: October 4th, 2024 please repost!

Important info on the state of nonhuman primate research in the US. This is such a core part of neuroscience work. www.jneurosci.org/content/44/3... #neuroskyence

Just created a list with the sensorimotor people I was following/followed me (inclusion criteria slightly generous) Let me know if you want to be added, and repost (?) to spread the word go.bsky.app/U4oyFgw

The latest MotorNet release (v0.2.0) is live! This includes big changes, first and foremost, a COMPLETE SWAP from TensorFlow to PyTorch. As usual, you can install it via a pip command. motornet.org

Here is a list of people doing sensorimotor research and that have a BlueSky account: bsky.app/profile/did:... Too bad most of them are barely active here but this shows that there is potential….

New paper out this week in Nature! nature.com/articles/s41... Many thanks to the co-authors for making this happen, especially co-senior / best friend @juangallego.bsky.social, and co-leads Mostafa + Joanna! I also want to say a word about the translational implications 👇

Seems apt that this huge leap forward in decoding methods would come out just a day before this thought-provoking piece on decoding, zombies, and consciousness! #neuroskyence #consciousness onlinelibrary.wiley.com/doi/10.1111/...

Awesome work led by @mehdiazabou.bsky.social and @evadyer.bsky.social towards unifying large scale datasets into a single model. The real gem here is the spike tokenization, super clever way to solve a key problem. Check it out!