@macshine.bsky.social talks with @melcooperphd.bsky.social about her new work showing that astrocytes—long dismissed as the brain’s housekeepers—are wired together in precise, long-range networks that remodel in response to experience. #neuroskyence www.thetransmitter.org/astrocytes/t...

Ooof... this paper on AI use in academic writing, based on submissions to the journal Organization Science. Sadly agrees with my anecdotal observations as an editor. AI-tinged submissions have increased, and readability and quality have decreased. pubsonline.informs.org/doi/full/10....

GABA is also an important metabolite directly converting alpha-ketoglutarate into succinate among other functions.

Thrilled to share our work out in @nature.com today! Linking flexibility modeling, single-cell imaging, and targeted optogenetics allowed us to characterize how some prefrontal neurons, and mPFC-VTA neurons in particular, drive contingency degradation behavior. www.nature.com/articles/s41...

Looking for a lab where the vibes (…and science) are ELITE 😮‍💨👌? Come join us in the Kash Lab ⬇️⬇️⬇️

🧠 CAHBIR offers comprehensive Brain Imaging services to meet your clinical trials needs. 🔗CAHBIR capabilities brochure: brainhealthinstitute.rutgers.edu/wp-content/u...

How does the brain rapidly distinguish similar memories? We use 7T fMRI to show dynamic shifts between pattern separation and reinstatement signals in hippocampal CA3 and DG with changing task demands: doi.org/10.64898/202...

You know GABA as an inhibitor, but that’s not all! We found that tonic GABAergic signaling, mediated by SST-interneurons and alpha5-type receptors, paradoxically facilitates dendritic calcium signals! www.sciencedirect.com/science/arti...

🚨Exiting new preprint from Lerner Lab postdoc AJ Miller-Hansen examining the thalamus as a physiological driver of local, acetylcholine-dependent dopamine release! 🚨 DA-ACh interactions have been 🔥but what’s really going on in vivo? We think we have some answers. #neuroskyence🧪

🤖🫧💥

Not to mention the NUMEROUS other issues of NIH-fail that have been discussed by me over the years. 😡

People who have not contacted me on the issue, have not RT'd my posts or given any evidence of giving one single shit about it. Their affection for speaking truth to power is new. The topics, limited. Interesting microcosm reflecting the way the Democratic party treats its most reliable base voters.

It is sort of fascinating to get contacts from people who want me to join their fight against the regime on behalf of NIH interests. People who, afaik, have made not one peep in 15 years about the Ginther gap.

"If you swap [unfunded Black PI apps] out for applications funded to white PIs this would reduce the funding rate ..to. 15.6% Which is still 46% higher than the award rate the applications from Black PIs actually achieved." From the Archive: The Endgame drugmonkey.wordpress.com/2020/06/16/t...

If you've ever sought NIH funding, do this now www.bioniclab.org/news/request...

The Deadliest Drug, a new investigative series, shows that the alcohol epidemic is a generational failure of the medical and public health systems, of industry, and of government. www.statnews.com/2026/05/12/a...

It was a huge honor to spend 90 minutes talking with Karl Friston about the origins of human brain mapping, the SPM software, and the 'finishing school' at the FIL. Tune in here:

The Ministry is going to regret publishing these numbers. I can't say more than that yet. But I urge everyone at Queen's Park to dig into the very large increases in grants to students at a very small number of private vocational colleges. It's more than $13M.

Guys - the government admitted there was a problem in exploding aid to privatec colleges AT THE PRESS CONFERENCE WHERE THEY CUT OSAP. That's the fraud Ford is talking about. Government can't admit it because it was asleep at the wheel for several years while it was happening.

In 1 week: The Lake Conference on The Neurobiology of Mental Health. Excited! There, Tony Liu from the @deisseroth.bsky.social group and I will be speaking about the same challenge: getting high res brain activity measures of emotion/mood. Why so hard? /1 lakeconferences.org/conf/1ed63fd...

not subtle

New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...

University: Faculty, please take our survey to help us better understand if you're thriving! All confidential! Survey: Gender? Race? Years at Institution? Rank? College? I should've just put my name on the survey

What so many have experienced personally has been confirmed by a new study: AI has been a disaster for working artists.

Excited to share new work now published in @cp-iscience.bsky.social Using single-neuron recordings in humans, we show that dopamine neurons encode reward expectations derived from past experience––giving us a new look into how reward learning unfolds in the human brain 🧵👇

Menstrual and estrous cycle related hippocampus plasticity: @liviaruehr.bsky.social does it relate to connectivity? Yes but won’t post non published data. I can’t wait for this to be out!! Both P related and E related changes! @cogneuroend.bsky.social 👏🏻👏🏻👏🏻

“If you ask tobacco companies to help write your school’s policy on cigarettes…you’re going to end up with guidance on how to smoke responsibly in school.”

California mice are paragons of monogamy. The neuronal bases of how they (or any other species) remember their partners is unknown. We found a surprisingly important role for hippocampal CA1 as the pair bond develops and a concomitantly diminishing role of CA2. www.biorxiv.org/content/10.6...

In 2003 I got a 5.2% and was told it would not be funded by NIMH…

Some kids are bypassing age-verification checks with a fake mustache

This age-based social media ban thing is totally going to be fine, no concerns here

Today at the Bordeaux Neurocampus, we had the privilege of listening to Meg Fox speak about her remarkable work on the striatal neurobiology of opioid use, and more specifically about her truly heroic effort to phenotype a line of Cre mice (the "weird" mice) which, in theory, should have been normal

Meet the academics refusing to use generative AI Researchers say they have their reasons for avoiding AI tools — and they’re sick of arguing about it. www.nature.com/articles/d41... h/t @maartenp.bsky.social

Kash lab at UNC is hiring a new technician (our current two are off to grad school!!) posting will go live soon, email me CV and names of references if interested.

From cells to behavior, this #OptoGRC2026 session explores how neural activity shapes behavioral outputs 🧠⚡ Featuring @j9kwapis.bsky.social, Catherine Peña, @nicoleferrara.bsky.social, Kevin Franks, Priya Rajasethupathy, Jennifer Lawlor & Yasmine Ayman, you won't want to miss this lineup!

Join us for an exciting #OptoGRC2026 session on advances in microscopy, tool development & sensors 🔬⚡ With @ismail-ahmed.bsky.social & speakers @ianoldenburg.bsky.social, Olivia Masseck, Linlin Fan, @sagescientific.bsky.social, Tommaso Fellin & Adam Gordon-Fennell!

This is the May cover of NN but it has already been debunked on biorxiv www.biorxiv.org/content/10.6... Such a clear statement about the ridiculous pace of publishing (not just NN).

Amazing science and the second best GRC site

🤩 So proud to have contributed to this work: Sex-specific role of microglia in Δ9-THC-induced disruption of fear memory reconsolidation www.nature.com/articles/s41...

Tim Spellman demonstrates his open-source tool, FlexRig. Read the paper for the full instructions and parts list to build the tool. #eNeuro #OpenSourceTools https://doi.org/10.1523/ENEURO.0364-24.2024

Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum

Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum https://www.biorxiv.org/content/10.64898/2026.05.08.723861v1

Download our updated database of postdoc fellowships from different foundations and agencies. We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc. Download this database here: research.jhu.edu/rdt/funding-...

Out in Science. Years ago I recall another paper that said how fields make bigger leaps in the few years after one of the "greats" retires. www.sciencemagazinedigital.org/sciencemagaz...

Good Morning Cape Town! Registration opens at 06:30 this morning. Pick up your registration badge and get ready for the week ahead at #ISMRM2026. CTICC 1 | Registration Area (Jasminum) Saturday: 06:30–18:00 Sunday: 07:00–19:00 Monday: 06:30–18:30 We’ll see you soon.

#eNeuro | A Multi-Network Approach Identifies Proteins Related to Dendritic Spines in Alzheimer’s Disease https://doi.org/10.1523/ENEURO.0468-25.2026

Full band in the studio this summer! LP coming soon.

Testosterone Administration Modulates Competitive Choice via Ventral Striatum and TPJ https://www.biorxiv.org/content/10.64898/2026.05.05.722878v1

If you are a member of the scientific community wondering how to meet this moment, check out this excellent discussion between @holdenthorp.bsky.social and @timothysnyder.bsky.social. youtu.be/IWNDMwimUP0?...