Yesterday I had the privilege to give a virtual talk to undergrad and graduate students in Mexico about some of our work at @lieberinstitute.bsky.social. It was great to connect with the community, and giving it in spanish felt so special. #cienciaenespañol!

For #FluorescenceFriday 🧠🔬🧪 - mPFC projection neurons heading to ventral tegmental area 🟢 or the locus coeruleus 🔴. Processes on some of these GPF+ neurons are just AMAZING! Image credit to our Circuits team! @jorge-miranda.bsky.social @rehg-j.bsky.social and Daniel Olivares!

It is so nice to see some mPFC neurons lighting up. Maybe they know its friday and they are also excited for the weekend like me. #fluorescenceFriday #miniscope

Great feeling for a friday. First cell from the new rig. Still a lot of work to do on the rig, but we are patching. Feels like going back to your first love ❤️ 😍

Our work characterizing the respiratory depression caused by opioids and alcohols is finally out in the world! pubmed.ncbi.nlm.nih.gov/41632547/

For #FluorescenceFriday - unmistakably the blue spot 🔵 (locus coeruleus) - here labeled in a section of the mouse brain in pink with tyrosine hydroxylase (TH) 🔬🧠🧪 Image credit to the @lieberinstitute.bsky.social Circuits team - @jorge-miranda.bsky.social @rehg-j.bsky.social

Final paper of my PhD 🤗 www.nature.com/articles/s44... There is growing interest in how cognitive control may improve value-based decision making. However, we find that a recent paper overestimated the role of control in their task, leading to erroneous interpretations of dACC recordings.

Notice of Extension to Early-Stage Investigator (ESI) Eligibility Period by NIH: Investigators whose ESI end date was in Sept, Oct, or Nov 2025 will have ESI status extended through March 31, 2026 But what about if the end date was Dec 25 or Jan 26? grants.nih.gov/grants/guide...

For #FluorescenceFriday, activity-trapping experiments to better understand how amphetamine controls attention. RNAscope for glutamate neurons 🟢, inhibitory neurons 🔴 and our "ensemble" 🟣. Quotes for the loaded definition ;) Image credit to JHU neuro student Suhaas Adiraju 🧠🔬🧪

Oscillatory and aperiodic neural dynamics shape temporal perception and weighting of perceptual priors in ADHD profiles https://www.biorxiv.org/content/10.64898/2026.01.30.702812v1

So happy to share this preprint and so proud of @rehg-j.bsky.social and his hard work and determination. Here we showed circuit-specific effect after activation of mPFC-LC projectors to sustained attention during rCPT.

Finally on Bluesky and I’m really excited to share this latest preprint with @jorge-miranda.bsky.social in which we functionally examined the role of a medial prefrontal cortex (mPFC)- Locus Coeruleus (LC) circuit in regulating sustained attention. 1/7 www.biorxiv.org/content/10.6...

We are thrilled to announce that the preliminary program for the 2026 GRC on the Frontal Cortex is now live! www.grc.org/frontal-cort... Registration is now open for both the GRC and our GRS, chaired by @albitc.bsky.social and @jorge-miranda.bsky.social!

Happy to share that our paper characterizing PrL dynamics during sustained attention is finally out. This work was a collaboration between the @martinowk.bsky.social and Greg Carr groups at @lieberinstitute.bsky.social . www.nature.com/articles/s41... #Calicumimaging #miniscopes #rCPT #PrL

New paper, studying time-on-task related decrements in the rodent continuous performance task (rCPT). CPTs are used to assess attentional function in clinical settings and have been adapted for mice (rCPT). Sustained attention is the ability to focus on an activity or stimulus over time,