We’re kicking off our ‘Featured image’ series in 2026 with this beautiful image of a murine neural tube acquired by Christina Daly @christinaadaly.bsky.social from the Ogden lab @labogden.bsky.social. Read about Christina's research in our blog post 🔬⤵️: focalplane.biologists.com/2026/01/06/f...

Any of my neurodevelopmental connections looking for an opportunity? The @ucdavis.bsky.social MIND Institute is hiring “Robert E. Chason Endowed Chair in Translational Research,” where translational is defined broadly! Please check it out! recruit.ucdavis.edu/JPF07378

First #MicroscopyMonday of 2026 deserves some festive cells.

The winner of OneNeuro's November #FotoFriday #FluorescenceFriday contest is "Portrait of a Claustrocortical Neuron" submitted by Baldomero B. Ramírez Cantú in the Solange Brown Lab at @hopkinsmedicine.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/

Over a year of #FluorescenceFriday showcased biology in true 3D, from intact human tissues to neural and immune networks, tumors, and vasculature. Structure, context, and relationships. In biology, context isn’t optional, it’s ground truth (Alpenglow Biosciences)

Accidentally festive #Celegans gonad while trying out some awesome LUTs by @kwolbachia.bsky.social for #FluorescenceFriday 🧪🔬

Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...

If you have some time off these holidays have another look at our beautiful review on #LC neuropeptides 🔵🧠

Happy 2026! As we enter the new year, take a look back at our biggest discoveries and defining stories from 2025: https://www.simonsfoundation.org/2025/12/22/from-ringing-black-holes-to-restoring-gut-health-science-at-simons-in-2025/ #science #math

Bring it on 2026 :)

This is a really neat study - congratulations to the team! Has me wondering whether this will be more of a rule or a feature across different classes of neurons/neuron types with various specialized functions.

New Year, new paper from our lab. Emily Kramer used 3D light-sheet imaging and tissue clearing to examine the spatial architecture of mouse amygdala engram ensembles. onlinelibrary.wiley.com/doi/10.1002/...

Happy New Year, #gardening friends. Our yard with all its standing seedheads is a #wildlife wonderland this morning. Sound on to hear #birds symphony. Juncos, Cardinals, >8 Robins, Sparrows & Finches zoom across the sky & dig through lightly snow-dusted garden beds. #UrbsInHorto #Chicago #nature 🌱

To all my friends and colleagues, wishing you the best for a fresh start with 2026, and a year that brings happiness, adventure, prosperity, and courage to tackle any obstacles ahead 🙌

Happy 2026. Let's get it done.

Caught some cool timing with the moon rising over the Capitol coinciding with the tree lights coming on 🌕🎄

Fences Go Up Around Meridian Hill/Malcolm X Park – Do you believe in miracles? Fountains (and more) to finally be fixed!!?!! - Hold on to your hats: www.popville.com/2025/12/fenc...

The seasons of 2025: January 6, 2025 March 28, 2025 July 16, 2025 November 8, 2025 @capitalweather.bsky.social

Lots of excitement about a new treatment for an Alzheimer’s model in mice. Look, I’m pro science moving forward. But I’ve also been reading this literature for a while and seen claim after claim for a cure. I’ll follow the data with my eyebrows raised at big claims of cures for a horrible disease.

New post! There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost. Medical breakthroughs in 2025. Plus a serious note at the end. www.scientificdiscovery.dev/p/medical-br...

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵 rdcu.be/eVZ1A

Heads up I will be hiring a postdoc and some techs in the new year! Lots of ephys and fiber photometry. If you've got soon to graduate PhD students or undergrads, send 'em my way!

before I started my lab, I asked several senior PIs what their one piece of advice would be and PI pointedly said: “Know when to drop a project.” And that advice has been invaluable in my lab. There are always other projects to follow up on, dropping one isn’t a failure in and of itself.

Blog post: Just quit Quitting projects in science is hard, but we should be doing a lot more of it. open.substack.com/pub/arjunraj...

As we wrap up 2025, let's shine a spotlight on some of the articles YOU enjoyed the most! Check out the top downloads from the last 3 months of 2025 below 👇 1/6

Blustery winds creating some neat looking clouds

Why are these fir trees floating in a lake? These are Christmas trees pursuing their second career creating fish habitat. Fish and wildlife managers are improving fish management using trees. This is a great use of our trees after their retirement. Read about it at Our Trees, ourtrees.substack.com

Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬! focalplane.biologists.com/2025/12/19/v...

At the Smithsonian American Art Museum - “Grandma Moses: A Good Day’s Work” - on exhibit through July. Totally fascinating that she started painting at the age of 76. All these paintings have this very quintessential essence - like, I’ve seen this somewhere, I know this.

Crazy that there are so many of them. 90s were an amazing time for music.

The quoted post is a list of tried-and-true, reliable #nativeplants for beginners. 🌱 But what about the weirdos. The rarely-grown-from-seed. The fiddly little guys. Here is a thread celebrating some such plants I'm trying to grow. They are all native to my area (MD).

Pretty dramatic sunset tonight.

Whomever was my Secret Santa for the lab holiday gift party seems to really know my vibe ;). This was very fun - my neck hurts and my eyes are tired because I couldn’t stop puzzling once I started it 🍩🧩🎄

I had the opportunity to do the most enjoyable and, hopefully, meaningful work of my scientific career thanks to the leadership of former NINDS Director Walter Koroshetz. He and his team at NINDS created visionary scientific programs for the pain field. He will be missed...

Apropos of nothing I was reminded of this quote today by Bernard Shaw: “Do not wrestle a pig. You get dirty, and besides, the pig likes it.”

www.nature.com/articles/s42... great stuff and a treasure trove of important data. Well done @mattsapio.bsky.social and team at NIH.

Thought my kids might be starting to age out of the magic, but I’ve got some real believers ☺️

Check out our new preprint on STARIT for creating image-based tensor representations of molecular resolution spatial transcriptomics data that can be combined with deep learning computer vision models to recover cell-states based on subcellular heterogeneity: www.biorxiv.org/content/10.6... 🧵👇

The authors keep coming back to this notion of #alzheimers disease. But somehow it seems remain outside of the mainstream journals.plos.org/plosone/arti...

Another tree that decorates itself for the holidays is oak, not just one tree but over 500 species mostly in the north temperate zone. Acorns were an important food source for people before we invented agriculture, and there were large acorn-processing factories all over the world.

I really liked this paper - data supporting super interesting idea that Alzheimer's disease pathology may have evolved as part of an innate immune defense response to microbial infection. www.nature.com/articles/s41...

Number of BME faculty job opening is noticeably down this year. We just had this question at a faculty meeting and @pratted.bsky.social has the visualization for the answer.

Bioinformatics data is messy. Here’s the nightmare that almost broke me 🧵👇

A bumblebee taking a break to clean up on a Swamp Rose Mallow last summer for #magentamonday. #fallbackflowers #fallback to June 22. #bees #nativeplants

Just accepted for publication in Nature Comm. is our new assay ICLAP to measure proteins of low abundance in tissues, such as markers of senescence.

reposting for your niche Baltimore-adjacent frustration needs

For this frigid day, offering some color for the #nativeplants feed of these flowers from one of my dogwoods that produces this deep pink color

Unmown pasture with common milkweed (Asclepias syriaca) 🌍 🌱 🦋 #nativeplants #pollinators

You want to know about this site that lets you explore data collected by the HMS Challenger from 1872–1876, an expedition that laid the foundation of oceanography. 🌊 challenger-expedition.sams.ac.uk/explore

Absolutely devastating news about James Ransone. I don't even know what to say. Sending all my love to those who knew & loved him.