1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵 Preprint link 👇 www.biorxiv.org/content/10.1...

The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.

Does predictive coding work in SPACE or in TIME? Most neuroscientists assume TIME, i.e. neurons predict their future sensory inputs. We show that in visual cortex predictive coding actually works across SPACE, just like the original Rao+Ballard theory #neuroscience www.biorxiv.org/cgi/content/...

We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠

ICE vehicles waste a whopping 80% of the energy in their fuel. Electric vehicles are propelled by entirely different mechanisms. Energy enters the vehicle as electricity, which directly powers the drivetrain: EVs need not convert one form of energy to another resulting in much higher efficiency.

🚨Our preprint is online!🚨 www.biorxiv.org/content/10.1... How do #dopamine neurons perform the key calculations in reinforcement #learning? Read on to find out more! 🧵

And High-throughput synaptic connectivity mapping using in vivo two-photon holographic optogenetics and compressive sensing www.nature.com/articles/s41...

In our Trends in Cogn Sci paper we point to the connectivity crisis in task-based human EEG/MEG research: many connectivity metrics, too little replication. Time for community-wide benchmarking to build robust, generalisable measures across labs & tasks. www.sciencedirect.com/science/arti...

Head direction cells use a head-referenced dual-axis updating rule in 3D space https://www.biorxiv.org/content/10.1101/2025.09.17.676760v1

1/ 🚨 New preprint! 🚨 Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇 📄 www.biorxiv.org/content/10.1... 💻 code + data 🔗 below 🤩 #neuroskyence

« Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells. » A fundamental study now published @elife.bsky.social elifesciences.org/reviewed-pre...

Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1... Read the thread below for a summary of our findings 🧵1/11

🔴 Le pire et le meilleur des aménagements cyclables à Marseille Incohérences dans les tracés, besoins d'équipements et sentiment d'impuissance des cyclistes... Marsactu tire le bilan de son enquête participative sur le vélo à Marseille et interpelle la métropole. ➡️ https://l.marsactu.fr/8li

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

🎉 Excited to share our paper out in EJSP - showing that vicarious touch, i.e. observing human-pet tactile interactions, can reduce stress, in times of social touch deprivation such as the first COVID lockdown ! Co-led with @marianavonmohr.bsky.social, in collaboration w/ @katerinafoto.bsky.social

Noncanonical circuits, states, and computations of the hippocampus | Science www.science.org/doi/10.1126/...

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

📢 [PARUTION] "QUI VEUT LA PEAU DE LA SCIENCE?" Un numéro spécial du @le1hebdo.bsky.social, conçu avec amU, à l’occasion du Festival des Sciences et des Arts "Science & croyances" (16–20 sept).

Dear colleagues, we have an open PhD position in computational neuroscience - spatial memory models and intracranial recordings - fully funded. Re-advertised, candidates are ideally available in the near future. A collab. with 4 labs. Apply here: tinyurl.com/yc84ctap

Happy to share our new paper with Mathilde Nordlund and Julie Koenig out @currentbiology.bsky.social. We used virtual reality in mice to study hippocampal distance coding. Our results suggest a primary contribution of grid cells to distance over cue-dependent place cell coding. shorturl.at/63yFo

Félix Vallotton ~ 1865 - 1925 Rade à Trégastel - 1917 Oil on canvas. Private collection.

There's a very cool Buzsaki #neuroskyence paper out in Science this week, looking at hippocampal spatial information encoding by multiple interneuron subtypes in parallel. The brilliant @agonru.bsky.social and I wrote a wee perspective to go alongside it: www.science.org/doi/10.1126/...

Not that it comes as much of a surprise to many of us, but it's worth emphasizing once again - the 👏 brain 👏 uses 👏 distributed 👏 coding 👏. 😁 Two new papers from the #IBL looking at brain-wide activity: www.nature.com/articles/s41... www.nature.com/articles/s41... #neuroscience 🧪

The two key studies of the International Brain Laboratory @intlbrainlab.bsky.social are out today! A brain-wide map of neural activity during complex behaviour www.nature.com/articles/s41... Brain-wide representations of prior information in mouse decision-making www.nature.com/articles/s41...

Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.

Happy to share our new paper by Aurélie Brécier*, Gaëlle Mailhos* and all, combining LFP and Miniscope to study L1 NDNF neurons diversity Layer 1 NDNF interneurons form distinct subpopulations with opposite activation patterns during sleep in freely behaving mice | PNAS www.pnas.org/doi/10.1073/...

Our work looking into heterogeneous pyramidal neurons (PNs) in hippocampal CA3 is now online @cp-cellreports.bsky.social: www.sciencedirect.com/science/arti... With a pile of multicellular recordings from mouse CA3, we characterised the recurrent network at the single cell level...

Slow synaptic plasticity from the hippocampus underlies gradual mapping and fragmentation of novel spaces by grid cells https://www.biorxiv.org/content/10.1101/2025.07.30.667696v1

“Air pollution fell substantially as Paris restricted car traffic and made way for parks, people-streets and bike-lanes.” Better for the climate, better for health, better for livability & quality of life. Common sense. Such a no-brainer, it’s remarkable that more cities HAVEN’T done the same.

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu! 🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you! 🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...

I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab! We explored how behavior, senses, and neurons influence how much information in the brain changes over time. www.nature.com/articles/s41... #science #research #neuroscience #hippocampus #placecells

Particularly informative spatial cues produce a higher and narrower bump of activity in the Drosophila head direction system. These informative cues can instruct the remapping of other cues to produce a self-consistent map. www.nature.com/articles/s41...

The new issue is out👉https://www.cell.com/cell/current ⁠ On the cover, Eliav et al. reveal that hippocampal replays in bats flying in very large, naturalistic environments were highly fragmented and short, depicting trajectories covering only a small portion of the environment size.

Remote activation of place codes by gaze in a highly visual animal www.nature.com/articles/s41... - very cool study with chickadees!

Fantastic to see this collaborative work with Hopi Hoekstra out in Nature (tinyurl.com/3at3zvby). Lead by @felixbaier.bsky.social and @katjareinhard.bsky.social. Not possible without @bramnuttin.bsky.social , Chen Liu and @arnausd.bsky.social. Excited to see where this work leads.

And here is a link that works: www.biorxiv.org/content/10.1...

Introducing our new favorite stimulus. A few minutes are enough to map the visual preferences of thousands of neurons. Mapping the visual cortex with Zebra noise and wavelets www.biorxiv.org/content/10.1... By Sophie Skriabine and Max Shinn, with Samuel Picard and @kenneth-harris.bsky.social

Voir Montrer Regarder 👀 Observer Mesurer Vérifier #SciArt If you are in Paris in September check out our exhibit “Regards Croisés”: Come for the Art, stay for the Science ! This scientific outreach event is supported by @c-brains.bsky.social, @sppin-cnrs.bsky.social and the Capitainerie de l’Isle.

If you are in Paris on October 1-3 : we are organizing a fantastic cognitive neuroscience conference at Collège de France, on topics ranging from language to math, education and consciousness, with many of my favorite scientists ! Full program here: www.unicog.org/seeing-the-m...

🎉 Heron is finally out @elife.bsky.social! Led by George Dimitriadis, with Ella Svahn & @macaskillaf.bsky.social 🧪 🧠 🐭 🤖 If you wonder why yet another tool for experimental pipelines, read the 🧵 below: #neuroscience #neuroskyence #OpenSource 1/ elifesciences.org/articles/91915

A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...

**in CA1… CA3 might operate a bit differently, per Fig 2d here: www.nature.com/articles/s41...

Really interesting results, suggesting that long-term place field stability is not from long-lasting synaptic plasticity, but is instead from an increased *probability of plasticity induction* in subsequent days.

I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social ! With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding. (1/13)

Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠 rdcu.be/evWtz

👨‍💻 Open PI position in our institute 👨‍💻 !! If you are an expert in Computational Neuroscience and want to start your lab in Bordeaux, contact us ! www.fens.org/careers/job-... @neuromagendie.bsky.social @neurobordeaux.bsky.social

Navigating the value space during choice Rhesus macaques represent choices as navigation trajectories in a value space using a grid-like code www.cell.com/cell/fulltex...