Does predictive coding work in SPACE or in TIME? Most neuroscientists assume TIME, i.e. neurons predict their future sensory inputs. We show that in visual cortex predictive coding actually works across SPACE, just like the original Rao+Ballard theory #neuroscience www.biorxiv.org/cgi/content/...

New preprint! How can you remember an image you saw once, even after seeing thousands of them? We find a role for humble mid-level visual cortex in high-capacity, one-shot learning. doi.org/10.1101/2025.09.22.677855 🧵🧪1/

The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible! www.sciencedirect.com/science/arti...

1/ 🚨 New preprint! 🚨 Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇 📄 www.biorxiv.org/content/10.1... 💻 code + data 🔗 below 🤩 #neuroskyence

Multisensory coding of self-motion and its contribution to navigation — a Review by Dun Mao & Yong Gu www.nature.com/articles/s41... #neuroscience #neuroskyence

excellent writeup by @thegeekygoth.bsky.social on the MICrONS project to build large-scale connectivity maps of the brain, with some small comments by me. I have been blown away by all the connectome work and really do think it will change neuroscience forever www.the-scientist.com/a-map-of-the...

Noncanonical circuits, states, and computations of the hippocampus | Science www.science.org/doi/10.1126/...

Oxytocin controls both sides of the mother-pup relationship in mice, influencing how pups communicate when separated from their mothers, a new study finds. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/oxytocin/oxy...

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric. www.biorxiv.org/content/10.1...

Early unilateral auditory deprivation can cause lasting spatial #hearing deficits. @anbuhlk.bsky.social &co show that unilateral #HearingLoss during development (but not adult-onset) impairs binaural #brainstem function & spatial hearing acuity in guinea pigs @plosbiology.org 🧪 plos.io/46njw1P

Proud to take on this challenge: building the new Centro de Neurociencias Cajal @institutocajal.bsky.social into a space where neuroscience crosses boundaries and transforms how we understand the 🧠!!

Excellent new review by @claireocallaghan.bsky.social on how noradrenaline drives learning across multiple scales of neurobiological organization - from cells to networks www.cell.com/trends/cogni...

In The Transmitter's reading list, we highlight the most anticipated upcoming neuroscience books and other notable 2025 releases. Featuring titles by @okaysteve.bsky.social, @dr-brein.bsky.social, @nicolecrust.bsky.social,‬ Xiao-Jing Wang and many more. By @franciscorr25.bsky.social bit.ly/45MvK41

Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement @kiahhardcastle.bsky.social @olveczky.bsky.social www.nature.com/articles/s41...

I wrote a Comment on neurotheory, and now you can read it! Some thoughts on where neurotheory has and has not taken root within the neuroscience community, how it has shaped those subfields, and where we theorists might look next for fresh adventures. www.nature.com/articles/s41...

Is there a cognitive hierachy between ecto- and endotherms driven by brain size/neuron counts? Probably not. Very interesting opinion piece by @zegnitriki.bsky.social et al., shifting focus to sensory–motor integration to explain brain size differences.🧪 royalsocietypublishing.org/doi/10.1098/...

Evolution is more like a tinkerer than an engineer. New things happen not by perfect engineering but by working with what's already available and repurposing existing objects through recombinations and modifications. This is a classic lesson for any kind of innovation, including that of new ideas..

Now out in @cp-cellreports.bsky.social: PV and SOM cells play distinct causal roles in controlling network oscillations and stability with Matteo di Volo and Farzin Tahvilli www.cell.com/cell-reports...

Our current approach to defining neural populations is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics, writes @markdhumphries.bsky.social #neuroskyence www.thetransmitter.org/systems-neur...

My team has updated our free database of POSTDOC fellowships. This database contains 286 entries. For each entry, we provide a link, short description, deadline, amount, and eligibility criteria. Download this updated and expanded database here: research.jhu.edu/rdt/funding-...

How is the nervous system organized to coordinate behavior? To approach this massive question, a team led by @asbates.bsky.social, @jasper-tms.bsky.social, @mindyisminsu.bsky.social, & Helen Yang present the BANC: a Brain and Nerve Cord connectome. Preprint: doi.org/10.1101/2025... 🧪#Neuroskyence

The review/perspective piece @wbialek.bsky.social traces the roots of the 2024 NobelPrize back to Hinton & Hopfield, highlighting their foundational contributions to neural networks. It explores the evolution of AI, considers its future through the lens of physics. journals.aps.org/prxlife/abst...

🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...

'Slow synaptic plasticity from the hippocampus underlies gradual mapping and fragmentation of novel spaces by grid cells' www.biorxiv.org/content/10.1...

I continue to think interneuron circuits are an untapped inspiration in neural network design for context-dependent computation.

Neural manifold properties can help us understand how animal brains deal with competing and multifaceted information, execute flexible behaviors and reuse common computations, writes @mattperich.bsky.social. #neuroskyence www.thetransmitter.org/neural-dynam...

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

When neurons change, but behavior doesn’t: Excitability changes driving representational drift New preprint of work with Christian Machens: www.biorxiv.org/content/10.1...

Biologist folk (especially in evolutionary biology and/or ecology, but it don’t matter): Can you give me your favorite examples of trade offs in biology? Organism or system don’t matter. Primary literature or reviews preferred.

More incredible work from the Drosophila field. 📌

🚨Very happy that my PhD work is now out in @nature.com! We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments www.nature.com/articles/s41... This was a truly collaborative effort! 🧵⬇️

Super interesting and kind of lovely discussion about childhood, across cultures… open.spotify.com/episode/7BIW...

One of the “golden videos” that I took during my Grass Fellowship @grassfoundation.bsky.social - active sleep in these little guys is so obvious and flamboyant! @mblscience.bsky.social

How can we test theories in neuroscience? Take a variable predicted to be important by the theory. It could fail to be observed because it's represented in some nonlinear, even distributed way. Or it could be observed but not be causal because the network is a reservoir. How can we deal with this?

Beautiful work! Very cool that the cancelation of self-generated motion seems to rely on proprioception rather than efference copy. Electric fish seem to also use proprioceptive signals for their own cancelation of posture-specific sensory cues (www.cell.com/neuron/fullt....

1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social @wellcometrust.bsky.social

To identify fundamental neuroscientific principles that generalize across species, systems and circuits, neuroscientists must embrace an evolutionary perspective, argue Karl Farrow and @katjareinhard.bsky.social. #neuroskyence www.thetransmitter.org/systems-neur...

Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com #neuroskyence www.thetransmitter.org/open-neurosc...

🚨 New Paper Alert! 🚨 I’m very happy to share our newest paper in Cell, led by the brilliant Monika Moissidis. We show that PGC1a regulates the maturation of PV+ interneurons in an activity-dependent manner. Link below 👇 www.cell.com/cell/fulltex... @cellpress.bsky.social @marinlab.bsky.social

🚀 We are excited to share that bombcell is now available in Python! 🐍 Automatically sort your units into good/MUA/noise/non-somatic using quality metrics and interpretable & adjustable classification thresholds. pip install and play around with our toy dataset: 🔗 github.com/Julie-Fabre/...

I’m very excited to share that I will join the University of Utah Department of Neurobiology as an Assistant Professor in Jan 2026!! 🎉🏔️🏜️ My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?

I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social ! With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding. (1/13)

Retinal waves reveal axial biases in modular patterns of cortical activity that predict future orientation preferences https://www.biorxiv.org/content/10.1101/2025.07.09.663735v1

Our study is out in Nature! Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models. 👉 www.nature.com/articles/s41...

Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠 rdcu.be/evWtz

Fruit fly sleep looks different, but new research finds that Drosophila brain responses to sensory patterns resemble those in vertebrates. This could help us understand how sleep evolved in the first place. By @siddhantpusdekar.bsky.social #neuroskyence www.thetransmitter.org/sleep/drosop...