Shots taken 4h apart - Autumn at Guy’s campus

Happy Bonfire Night! 🎇🎆

Had a bad day? At least you were not in charge of choosing the password for the Louvre's video surveillance server.

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2/n Scientific heroes from the past had v different experiences / opportunities. His wife "..ran their households, hosted exuberant parties and raised their children. In short, she provided an environment in which Crick had the luxury of devoting all of his energy to his intellectual life." and..

Francis Crick's book The astonishing Hypothesis drw me into the field of neuroscience. He made huge contributions. but worth remembering... 1/n

Reminder this is happening this Wed/Thu. Free spiking neural network conference - registration required (see below).

Worth a read 'Comparative study of pre- and post-mortem perfusion of fixative for the quality of neuronal tissue preparation' www.nature.com/articles/s41...

Anyone who has been actively recruiting STEM graduates over the last decade feels this plot in their bones.

The week ends, the inbox smiles: paper accepted 😎

*2 papers to review

We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience recruiting.paylocity.com/recruiting/j...

Probably the coolest piece of equipment in our lab right now

Mitral and tufted cells in the olfactory bulb (cyan) with their axon initial segments (AIS, red). All fluorescence is endogenous - no amplification! The mouse expresses tdTomato in the whole neuron and GFP exclusively in the AIS. 🔬 🧠

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions, writes Xiao-Jing Wang. #neuroskyence www.thetransmitter.org/neural-dynam...

Drawings for Algernon

Oh no! The mouse in the whiteboard has gained consciousness

My legacy: passion for science and parties (I love reading thesis acknowledgments)

Always keep your Spanish friends close - they tend to surprise you with the best presents 🤌🏼

The one and only pipetboy of the lab disappeared during the same timeline as the Louvre heist. Coincidence?

"Even short, regular check-ins can make a difference. Time spent helping students to solve problems, or simply asking how a project is going, will pay dividends. It also saves time later by catching small problems before they become big ones" nature.com/articles/d41...

I am thrilled to share our latest work: we identified a population of central amygdala neurons that promote the earliest and perhaps most important social behavior: pup suckling!... We also developed new tools for pup neuroscience Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab

Neuronal Migration: How hunger guides new brain cells to their destination elifesciences.org/articles/109...

Nothing like saying aloud “only a few more recordings to close the dataset” for everything to stop working 🥲 this woman never learns

Patterns recur through various mythologies: floods, tricksters, battles with monsters, creation and apocalypse. Some scholars believe there is a common source—and hope to find it.

Intrinsic dendritic integration features of prefrontal layer 5 pyramidal cell subclasses www.jneurosci.org/content/earl...

Correction for multiple comparisons should be ubiquitous www.nature.com/articles/s41... 👍👏

Great review on The Genetics of Human Handedness: Microtubules and Beyond www.cell.com/trends/genet... - handedness is such an interesting phenotype!

Listening to this, it's super inspiring! Especially the bit where they say that you'll never feel 'ready' to apply for a position, so might as well do it when it's feasible. www.storiesofwin.org/profiles/202...

It’s #FluorescenceFriday! Fresh off the confocal: axons of olfactory sensory neurons (green, GFP) projecting into a glomerulus (nuclei in magenta) in the mouse olfactory bulb 🧠🔬

Want to make publication-ready figures come straight from Python without having to do any manual editing? Are you fed up with axes labels being unreadable during your presentations? Follow this short tutorial including code examples! 👇🧵

Not even pretending this wasn’t luck Wordle 1,580 3/6 ⬜⬜🟨⬜⬜ 🟨⬜🟩⬜🟨 🟩🟩🟩🟩🟩

Patch-Clamp Single-Cell Proteomics in Acute Brain Slices: A Framework for Recording, Retrieval, and Interpretation www.biorxiv.org/content/10.1...

Correlation Vs. Causation

Odor experience stabilizes glomerular output representations in two mouse models of autism www.eneuro.org/content/earl...

ICYMI, here is the press release for my study with @drjuliawester.bsky.social - we surveyed over 800 scientists who use social media. They overwhelmingly agree that Twitter is no longer useful or pleasant, and that for all professional online scientist goals, Bluesky is superior. 🧪 #SciComm 🌍

First time I witness a racist attack on the London tube. Random man starts punching whoever is 'foreign' looking for him while shouting xenophobic sh*t. The British transport police is informed. The current political climate defends and encourages these things. Stay safe out there, fellas.

Model organisms as platforms for training scientific minds www.nature.com/articles/s41...

PREACH! www.nature.com/articles/s41...

No words

Post-pub Friday night science 🧠🔬

We have a fully funded PhD studentship exploring glial cell development with techniques ranging from molecular neuroscience to system biology. tinyurl.com/2jxezabw Come and join our interdisciplinary team with Ruth Williams and Beatriz Bano Otalaro #multiomics #singlecell #physiology

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

Activation of GluN2D-containing NMDA receptors promotes development of axons and axon-carrying dendrites of cortical interneurons academic.oup.com/cercor/artic...

We are recruiting PhD students! If you are interested in evolutionary neuroscience, consider applying: www.crick.ac.uk/careers-stud...

"Reproducibility isn’t glamorous, but it’s essential." @annechurchland.bsky.social speaks candidly in @thetransmitter.bsky.social about the obstacles to reproducibility and shares practical advice for other neuroscience labs. 🧠📈 www.thetransmitter.org/reproducibil...

Thought-provoking discussion about how Brexit affects Spanish scientists in the UK, organised by the SRUK at the Embassy of Spain in London. The food was over the top! Tortilla, croquetas, empanada… Truly the best way to host an event 😎

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back. I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support