This is promising, but they also need to think about the NHS surcharge. Most of the costs come from there, really.

don't release preprints without a Methods section don't release preprints with a Supplementary Materials section don't release preprints without data don't release preprints without code use preprint servers to share your science, not advertisements

😮‍💨😮‍💨 Connections Puzzle #833 🟦🟦🟩🟦 🟦🟩🟦🟦 🟨🟦🟩🟦 🟨🟨🟨🟨 🟦🟦🟦🟦 🟩🟩🟩🟩 🟪🟪🟪🟪

Saturday. My mice are born, so I need to patch. I’m in the lab. I forgot my headphones at home.

Bringing from the bad place this bulbar dopaminergic neuron with 3 (!!!!!) AISs for #FluorescenceFriday 🧠

Looking at different places along the axon, we found most of the spontaneous exocytosis occurring in… the axon initial segment! In addition, acute perturbation of the actin-spectrin scaffold could up-regulate shaft exocytosis vs presynaptic release. 6/11

Haoming won best poster at last year’s retreat, and now Ana takes home best talk! The team is on a roll!

SCN2A loss is strongly linked to neurodevelopmental delays and, at times, seizure. In an amazing collaboration with @nadavahituv.bsky.social, led by Serena Tamura, Andrew Nelson, and Perry Spratt, we leveraged CRISPR activator approaches to rescue this loss. rdcu.be/eGU0W

Really exciting new paper from collaborator extraordinaire @neurobender.bsky.social on CRISPRa-mediated rescue of Scn2a loss-of-function. Happy to contribute a tiny bit to this behemoth of a story. Congrats, Kevin, Nadav, and everyone else!

And, of course, congrats to the other awardees! The science in this department is top notch, and it shows! 🧠

On the way back to London after 2 amazing days sharing science in the CDN department retreat - and look what I got!

Inspired on the London tube, we present you Neural Tube! The most relying transport for your developmental neurobiology journey. PS: can you spot the puns?

In September 1919, Escher moved to Haarlem to study architecture. His landlady in Haarlem gifted Escher a white cat, who stayed his pet and companion during his student years. Escher lovingly portrayed his cat in several wood cuts. Etches of a white cat by M.C. Escher

Regional heterogeneities of oligodendrocytes underlie biased Ranvier node spacing along single axons in sound localization circuit elifesciences.org/reviewed-pre...

In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance www.biorxiv.org/content/10.1...

Anybody who speaks English as a second language and/or has a "non standard" accent could tell you this for free for centuries

Posters printed (5x), talks made (2x), symposia chairing ironed out (2x), preprint posted (1x), whole lab on board (7x): 𝐁𝐢𝐥𝐛𝐚𝐨, 𝐡𝐞𝐫𝐞 𝐰𝐞 𝐜𝐨𝐦𝐞! #ECRO2025 🇪🇸🧠👃 ecro2025.com @chloeg-neuro.bsky.social @harinw.bsky.social @connordoyle.bsky.social @ailiemcwhinnie.bsky.social @neurosana.bsky.social

A collage for #FluorescenceFriday and the background of the intro slide of my next talk!

Approximately 92 percent of the time you type parent's you mean parents'. Approximately 97 percent of the time you type lightening you mean lightning. #copyediting

The tube strikes had me walking the 7.1 km between home and work, which means I got to do a little workout while enjoying the sunny morning ☀️🏙️

One of the best parts of science is to put your new and exciting results together for a talk. And a poster. All at once. Even better with the right soundtrack www.youtube.com/watch?v=4FLj...

“Happiness is already success”, Carlos Alcaraz

We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)

Golden hour with St Paul’s in the horizon

Literally me

Pretty much the vibe

Phew! Wordle 1,537 6/6 ⬜⬜⬜⬜⬜ ⬜⬜⬜⬜🟨 🟨🟩⬜⬜⬜ 🟩⬜🟨⬜🟨 🟩🟩⬜🟨⬜ 🟩🟩🟩🟩🟩

Oh, I know what I'm reading today 'Absence of short-term axon initial segment plasticity in human, mouse, and rat cortical circuits' www.biorxiv.org/content/10.1...

The Neuronal Primary Cilium is a Key Regulator of Homeostatic Plasticity www.biorxiv.org/content/10.1...

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...

We’re delighted to have the one and only Paul Jenkins @pjenkinslab.bsky.social in the department today! We are all in for a treat…💥

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, [email protected], PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...

My niece did this for a school work to talk about what her aunt does and I am melting 🥰

Pre-Sensory Spontaneous Activity Accelerates Coordinated Maturation of Synaptic Partners and Drives Transition to the Mature Physiological Phenotype www.biorxiv.org/content/10.1...

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Summer reads, but it’s only women writers 📚 Cat Bohannon 🇺🇸 Beatriz Serrano 🇪🇸 Han Kang 🇰🇷 Jacqueline Harpman 🇧🇪 #BookSky

Adam Raine, 16, died from suicide in April after months on ChatGPT discussing plans to end his life. His parents have filed the first known case against OpenAI for wrongful death. Overwhelming at times to work on this story, but here it is. My latest on AI chatbots: www.nytimes.com/2025/08/26/t...

Editor searching reviewers in August

Our manuscript characterising tissue-specific consequences of tagged protein fusions in CRISPR-engineered mice is now online @PLOSGenetics. journals.plos.org/plosgenetics.... Thanks again to all coauthors, reviewers and editors for a smooth publication process. Brief summary below.

Inspired by @deniswirtz.bsky.social and team, I'm collating a database of #PhD and #postdoc fellowships in the #EU. I'm standardising the information an entry needs, making it easier to (1) search and (2) contribute - and I would appreciate input, especially from other #ECR! Please share! 1/3

Obstacle #2 (or maybe just a companion)

Inducible NMDA receptor knockdown reveals a maintenance phase in dendritic refinement of barrel cortex neurons www.cell.com/iscience/ful...

Objective: reviewing a grant Obstacle:

This is not a drill! 1 week to deadline! 🚨

POV: you are a cat trying very hard to nap, but there’s a crazy 5-yo running around 🤪🫣

Female graduates in the UK fall behind men from the very start of their careers, even when they have taken the same courses, and are out-earned after studying more than four-fifths of university subjects (1/3) www.ft.com/content/cb0e...

When kainate receptors go wrong: GRIK2 mutations connects seizures with wide-ranging behavioral changes. Check out @pushpinder2002.bsky.social 's first #preLight, which talks about the work by Brynna T. Webb and the team.

She thinks I can’t see her 😼

🧠 Position still opened! Don't hesitate to apply if you want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders!