First paper from the lab! We propose a model that separates estimation of odor concentration and presence and map it on olfactory bulb circuits Led by @chenjiang01.bsky.social and @mattyizhenghe.bsky.social joint work with @jzv.bsky.social and with @neurovenki.bsky.social @cpehlevan.bsky.social

Simultaneous detection and estimation in olfactory sensing https://www.biorxiv.org/content/10.1101/2025.11.01.686013v1

Stoked to see our study out in final form! Big kudos to @jonathanamichaels.bsky.social for driving this along for the past 5 years.

🔷 Launch of the IVADO 2026 Postdoctoral Research Funding Program for outstanding national and international postdoctoral researchers. More info: ivado.ca/en/scholarsh... #AI #ArtificialIntelligence #R3AI #Funding #Postdoc

Applying to do a postdoc or PhD in theoretical ML or neuroscience this year? Consider joining my group (starting next Fall) at UT Austin! POD Postdoc: oden.utexas.edu/programs-and... CSEM PhD: oden.utexas.edu/academics/pr...

Apply to the new CSHL grad program in BioAI/neuroAI! (Masters degree or equivalent required in a quantitative area such as computer science, physics, mathematics, or engineering) www.cshl.edu/phd-program/...

Mila's annual supervision request process is now open to receive MSc and PhD applications for Fall 2026 admission! For more information, visit mila.quebec/en/prospecti...

Delighted to share that we are currently hiring for a tenure-track position (open rank) in Clinical Psychology in the Department of Psychology at McGill University. Come join a great department! Link to apply: mcgill.wd3.myworkdayjobs.com/en-US/mcgill....

This is one of the most outstanding examples of circuit understanding I've seen in a long time. The unification of theory and experiment is beautiful. When Malcolm presented this in my lab, the audience was cheering at the end, and one person shouted (non-ironically) "You did it!"

Finally preprinted! TL;DR: thalamic head-direction neurons can shape their activity regardless of input. Big thanks to @apeyrache.bsky.social and master experimentalist @sskromne.bsky.social .

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

For anyone on the neuroscience job market, our ads are up. We are looking for anyone working in systems neuroscience of animals to join us in southern Alberta 🇨🇦 #academicsky #neuroskyence #neuroethology #academicjobs #Canada neurojobs.sfn.org/job/39049/as...

Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience. #neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...

Since I'm back on BlueSky - with @frostedblakess.bsky.social and @cpehlevan.bsky.social we wrote a brief perspective on how ideas about summary statistics from the statistical physics of learning could potentially help inform neural data analysis... (1/2)

Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.

Having fun facilitating this amazing group of young Profs at the #Neuro4Pros workshop with @kordinglab.bsky.social and @meganakpeters.bsky.social, @yaelniv.bsky.social, and Hannah Bayer. Watch out world: this is the next generation of leaders! compneurosci.com/Neuro4Pros/i...

For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more #neuroskyence #academicsky

My first paper with @naoshigeuchida.bsky.social is finally out in @natcomms.nature.com ! rdcu.be/eACGf TL;DR: asymmetric learning rates can be induced by shifts in tonic dopamine giving rise to pessimistic/optimistic biases in agents or animals undergoing reinforcement learning .

🚨 I’m excited to say that my CIHR Project Grant was funded! My NHP lab is now full-speed-ahead, and I’m hiring experimentalists (postdoc, PhD student, and/or a tech/manager). We’ll do multi-region ephys during reaching/grasping in macaques, with behavioral and spinal perturbations.

New paper with @nathanieldaw.bsky.social in Nature Communications: an RL model that builds a successor map compositionally. The new model plans as well as the best models, and it links components of the map used for planning to neural codes in the medial entorhinal cortex. rdcu.be/eAofi

Our paper on foraging is now published in Neuron! Read it here: www.cell.com/neuron/fullt... This project was co-led by Michael Bukwich (not on Bluesky) and me, with major contributions from all co-authors. Huge thanks to the whole team!

A landmark volume, The Handbook of Dopamine, is now online: www.sciencedirect.com/handbook/han... Big kudos to the editors, Stephanie Cragg and Mark Walton, for putting this together.

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

👨‍💻 Open PI position in our institute 👨‍💻 !! If you are an expert in Computational Neuroscience and want to start your lab in Bordeaux, contact us ! www.fens.org/careers/job-... @neuromagendie.bsky.social @neurobordeaux.bsky.social

Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...

Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.

Thrilled to announce I'll be starting my own neuro-theory lab, as an Assistant Professor at @yaleneuro.bsky.social @wutsaiyale.bsky.social this Fall! My group will study offline learning in the sleeping brain: how neural activity self-organizes during sleep and the computations it performs. 🧵

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...

And one more again at McGill in artificial intelligence in Psychiatry can-acn.org/assistant-pr...

Preprint Alert 🚀 Multi-agent reinforcement learning (MARL) often assumes that agents know when other agents cooperate with them. But for humans, this isn’t always the case. For example, plains indigenous groups used to leave resources for others to use at effigies called Manitokan. 1/8

Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...

Two papers out today on RL in the dopaminergic neurons of the midbrain of mice (one from McGill's new PI @paulmasset.bsky.social). Both papers demonstrate heterogeneity in discount factors! www.nature.com/articles/s41... nature.com/articles/s41... 🧠📈 🧪 #NeuroAI

First pre-print from the lab: www.biorxiv.org/content/10.1...

1/6 Why does the brain maintain such precise excitatory-inhibitory balance? Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning. www.biorxiv.org/content/10.1... led by @jrbch.bsky.social

Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF

#preprint: We mapped the structure and function of olfactory bulb circuits with in vivo 2-photon microscopy and synchrotron #Xray holographic nanotomography. doi.org/10.1101/2025... @yuxinzhang.bsky.social @andreas-t-schaefer.bsky.social @apacureanu.bsky.social @crick.ac.uk @esrf.fr

Don’t miss the panel on the future of computational neuroscience at #HBHLSymposium2025 on May 7, 2025, with experts from McGill University, @camhnews.bsky.social & @westernuresearch.bsky.social. 🧠 Register now: mcgill.ca/x/iwgm @paulmasset.bsky.social @cognemo.bsky.social @tyrellturing.bsky.social

Blog post by Demba Ba, @saramatias.bsky.social and @btolooshams.bsky.social on our recent @cp-neuron.bsky.social paper proposing a new deconvolutional method based on algorithm unrolling to anlayze neural data across recording modalities

Interested in foundation models for #neuroscience? Want to contribute to the development of the next-generation of multi-modal models? Come join us at IVADO in Montreal! We're hiring a full-time machine learning specialist for this work. Please share widely! #NeuroAI 🧠📈 🧪

1/ Why do patients with late-stage cancer lose motivation & sink into apathy? 🔥 Our new Science paper shows chronic inflammation activates a cytokine-sensing brain circuit that lowers motivation. Huge team effort: Aelita Zhu, Sarah Starosta, Pignatelli & Janowitz labs! 🧵 🔗 doi.org/10.1126/scie...

Don't miss our #Cosyne2025 poster (3-128) 'Simultaneous detection and mapping in the olfactory bulb' proposing a new computational role for mitral and tufted cells in the olfactory bulb with Matthew He, @chenjiang01.bsky.social @neurovenki.bsky.social @cpehlevan.bsky.social @jzv.bsky.social

I'm excited to share that the last chapter of my PhD thesis is now published in Nature! 🍾 What drives serotonin neurons? We think it's the expectation of future reward and --- critically --- how fast this expectation is increasing. 📈 doi.org/10.1038/s415... 1/6

I’m happy to share our latest work (co-lead by Selina Qian) has today been published in its final form in @:natureneuro.bsky.social: Read here: https://www.nature.com/articles/s41593-025-01915-4 (1/12)

How can we design human-interpretable AI models to explain why neurons behave as they do? Excited to share our work in collaboration with @saramatias.bsky.social, Hao Wu, Simona Temereanca, @naoshigeuchida.bsky.social, @neurovenki.bsky.social, @paulmasset.bsky.social, and Demba Ba @harvard.edu 1/21

New Deep Learning Framework Reveals Hidden Structure in Neural Activity 🧠 #neuro #science www.mcb.harvard.edu/department/n... @naoshigeuchida.bsky.social @saramatias.bsky.social @neurovenki.bsky.social @btolooshams.bsky.social @kempnerinstitute.bsky.social @harvardbrainsci.bsky.social

By studying songbirds, our own Vikram Gadagkar, @neurokim.bsky.social, Jonathan Kasdin and colleagues witnessed the role the brain’s reward machinery plays as the brain naturally learns over time through practice. Learn more! zuckermaninstitute.columbia.edu/songbirds-hi...

Proud to have contributed to @jiaxuanqi.bsky.social's masterpiece out @nature.com! She shows that dopamine transients track the learned quality of song during juvenile learning and that dopamine release is driven not just by VTA firing, but by a local cholinergic mechanism! (1/x)

Our new study: Dopamine in the tail of the striatum facilitates avoidance in threat–reward conflicts. Congrats Iku-Tsutsui Kimura, Melissa Tian and others! Led by Mitsuko Watabe-Uchida. www.nature.com/articles/s41...

Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8