big fomo for @dopaminesociety.bsky.social next week but excited that @jessicamoretti.bsky.social and @matthiasfritsche.bsky.social from the lab attending to present what we have been up to

Excited to share our new paper published in Nature Communications! rdcu.be/fh6ty We show that deep layers of the superior colliculus identify the salience of conditioned visual stimuli and drive dopamine responses during classical conditioning.

Very interesting stuff here

We have new a new doctor in the lab 🍾🍾🎉Congratulations @neurorussell.bsky.social for successful viva today at Oxford @oxforddpag.bsky.social

Amazing study and the coolest results (from my point of view!) is that LC norepinephrine neurons projecting to the frontal cortex encode reward prediction error

I am livid that after less than a day, Vance et al are back empty-handed. "Marathon" talks?? They didn't even sleep on it and try again! Many thousands of lives, the world economy and world hunger, and more, hang in the balance, and they stopped trying after less than a day?? What a rotten failure.

We’re recruiting! Exciting opportunities in our lab supported by a @wellcometrust.bsky.social Discovery Award. • Postdoctoral researchers • Research assistant/PhD students Join us to study how neural circuits drive decision-making. Deadline 26/04 Learn more and Apply here: rezavallab.org

100+ year old Pasteur Institute in Tehran was a premier infectious disease research institute and vaccine manufacturer It is a reason Iranian kids like me born in 60s had access to measles vaccines soon after they were developed in the west

bombs falling to plant democracy! , but instead fertilising despair and taking lives… writing right after hearing that a few days ago bombs landed some 50 m from my father’s office ….

Actually the view from my office just got more interesting, as the official celebrations of the 200th anniversary now include a pirate projection saying "Free Palestine". Regardless of opinions, may UCL enjoy 200 more years of freedom of speech.

RA job alert. We are looking for a fearless experimentalist to join our experiments on cortical neuromodulators during visually guided learning, lead by @michael-lynn.bsky.social . Opportunity to learn 2p imaging, design and conduct experiments. RT plz. Apply here: my.corehr.com/pls/uoxrecru...

There is a new Postdoctoral Research Associate position available in my group, to work on computational analysis of human neuroimaging workflows to develop robust, interpretable and scalable biomarkers of cognitive brain health. Closing date 10th Feb 2026. www.imperial.ac.uk/jobs/search-...

Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization: doi.org/10.1117/1.NP...

We're running a 5th edition of the always-exciting UCL Summer School on Consciousness and Metacognition this year, 8th-10th July 2026 in London. Accommodation and travel expenses are covered. For more information and how to apply, check out metacoglab.org/summer-schoo...

This one from @kepecslab.bsky.social and Song Hu lab is awesome: www.nature.com/articles/s41...

New preprint. We show that in addition to reward prediction errors (RPEs), dorsal striatal dopamine signals encode sensory prediction errors (SPEs), the difference between sensory prior & observed stimulus. www.biorxiv.org/content/10.6...

We tend to think of neurons as either excitatory or inhibitory, but some neurons chemically inhibit their downstream targets while electrically exciting their neighbors. What is gained by having an inhibitory neuron excite its neighbor? www.biorxiv.org/content/10.6...

Please repost widely. @vanderhaeghenp2.bsky.social and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP jobs.vib.be/j/119852/pos...

concise and informative review article on corticostriatal pathways in sensory process by @giladsilberberg.bsky.social et al . I find myself looking into it frequently and learn/cross check a new thing every time : www.sciencedirect.com/science/arti...

We look forward to discussing these with you all #SfN25, #SfN2025

Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here: www.ucl.ac.uk/cortexlab/po...

Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...

All-optical experiments are great but @neurorussell.bsky.social found that opsin desensitization due to cross-talk between the imaging laser and the opsin causes major issues. These can be ameleorated with long inter-stimulus intervals & short imaging doses. All here: www.biorxiv.org/content/10.1...

Looking for a PhD next year? Want to come and work on the next generation of OPM-MEG/EEG biomarkers in computational psychiatry? Apply for our MRC iCase studentship with @mkflugge.bsky.social, collabs with @lilweb.bsky.social + industrial placement at P1Vital: www.medsci.ox.ac.uk/study/gradua...

Beautiful and clear results showing that temporal difference error calculation is hardwired in the dopamine/striatum mircocircuits: www.biorxiv.org/content/10.1... from @malcolmgcampbell.bsky.social and @naoshigeuchida.bsky.social

In our Learning Club @cmc-lab.bsky.social today (Aug 18, Thu, 2pm CET), Samuel Liebana will tell us about his paper (www.cell.com/cell/fulltex... [joint work w/ @saxelab.bsky.social & @laklab.bsky.social]. Want to attend, send an empty email to [email protected] to get the link!

Concise and informative highlight on our recent paper, thanks to Seung Chan Kim, Sehwan Kim & Sang Ryong Kim. www.nature.com/articles/s41...

Hagai Bergman - whose celebrated work was a critical step in identifying the subthalamic nucleus as a target for deep brain stimulation in Parkinson's disease - & Josh Goldberg, both of the Hebrew University of Jerusalem, helping to stop traffic (posted by Josh on X): Stop the war! Bring them home!

We are recruiting a new PI at the FIL @imagingneuroucl.bsky.social, Associate or Full Professor. This is an amazing place to do cognitive neuroscience, in the heart of London. If you or someone you know might be interested, please pass it on. #neuroskyence www.ucl.ac.uk/work-at-ucl/...

New preprint + thread 🧵 #Psychedelics induce the formation of new synapses, but where do they connect? Our rabies tracing study reveals that #psilocybin shifts connectivity across specific cortical networks. www.biorxiv.org/content/10.1... 1/12

Can we use what we’ve learned about cognitive maps to understand social cognition, including theory of mind? If you’re interested in answering this question then this is a fantastic postdoc opportunity with @mkwittmann.bsky.social in collaboration with @summerfieldlab.bsky.social and my lab.

Our paper on foraging is now published in Neuron! Read it here: www.cell.com/neuron/fullt... This project was co-led by Michael Bukwich (not on Bluesky) and me, with major contributions from all co-authors. Huge thanks to the whole team!

🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...

We're looking for a research assistant to work in our neuroscience lab at @princetonneuro.bsky.social @hhmi.org where we study learning and decision-making circuitry. Apply here: research-princeton.icims.com/jobs/21001/r... Pls share w/ anyone who might be interested!

2 Lecturer (Assistant Prof) positions available @yorkpsychology.bsky.social! Come join our department! #neuroskyence #cognition #psychscisky #neurojobs jobs.york.ac.uk/vacancy/lect...

A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...

Very happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...

New work! Learning is assumed to involve synaptic plasticity, but which specific synapses change to enable higher order cognitive functions? We actually find that cognitive flexibility involves potentiation of long-range GABAergic synapses from prefrontal PV neurons: www.biorxiv.org/content/10.1...

Assistant Prof/Associate Prof position in Mammalian Neuroscience! 👩‍🔬👨‍🔬 My department is hiring! Closing on June 30th. Please repost widely! www.jobs.ac.uk/job/DNK944/a...

Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...

Two awesome papers on dopamine neuronal computations , congratulations to authors

We’re hiring a postdoc with slice patch-clamp expertise to study head direction circuits and plasticity during spatial learning. Ideal for a neurophysiologist excited to combine ex vivo and in vivo approaches. Come join us in beautiful Cambridge! 🐭🧭🧠 📝 Apply by 9 June: www.jobs.cam.ac.uk/job/51282/

*** Come join us !! We are recruiting !! *** How does the brain generate beliefs that go beyond direct experience? How do these mechanisms go awry in psychosis? The Barron lab tinyurl.com/bdf4drjf @MRCBNDU @NDCNOxford are recruiting a new postdoc tinyurl.com/ut4vbwt4 to work in mouse models

The Hulme Junior Research Fellowship offers early-career researchers a unique opportunity to advance their careers. • Lead independent research projects • Publish in high-impact journals • Build multidisciplinary collaborations Deadline: 12 noon, Monday 19 May www.dpag.ox.ac.uk/work-with-us...

Our paper is out in Nature. By examining various inputs to the motor cortex during learning, we found that thalamic inputs learn to activate the cortical neurons encoding the movement being learned. Tour de force by Assaf in collab with Felix and Marcus. Congrats! www.nature.com/articles/s41...

Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti... "Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning" Congrats, Gaby!!!

First preprint from our lab! An @jerlich.bsky.social collaboration We developed novel frameworks to study multi-agent decisions in mice. Mice flexibly shift their decision preference under social competition, by integrating real-time self and opponent information! www.biorxiv.org/content/10.1...

Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...

Anyone looking for a PhD in NeuroAI (models of the visual system to spatial system)? @amansaleem.bsky.social and I are looking for someone to start in October. More details here: www.findaphd.com/phds/project... Get in touch with either of us if you’ve got questions!

🚨 New study alert! 🚨 Ever wondered if rats and humans learn in the same way? 🐭🧑‍🔬 We tested this — and the answer is yes, at least when it comes to how we value rewards in context. (with @shaunaparkes.bsky.social Lachlan Ferguson, Magdalena Soukupova) 🧵Thread 👇 1/ www.biorxiv.org/content/10.1...