Introducing the International Brain Lab AI Agent: a tool to help researchers analyze neural activity from across the mouse brain, using AI coding agents. Please try it! We would love your feedback. github.com/int-brain-la...

zetapy v4.0 is live! Due to various optimizations of the code it now runs 4x faster⚡Upgrade now and get your significant neurons in no time! pip install zetapy==4.0

This website shows you what your browser is leaking about you. sinceyouarrived.world/taken

Are you interested in serotonin receptors? I made a website which visualizes the expression of different 5-HT receptors! Data from the Allen Brain Atlas (@alleninstitute.org) website by the IBL Brain Viewer (@intlbrainlab.bsky.social). atlas.internationalbrainlab.org?buckets=meij... Instructions 👇

I've been watching Fireman Sam with my daughter (the new animated version) and I must say I'm deeply worried for the residents of Pontypandy, the small Welch village with a population of apparently 10 people. A thread 🧵

I'm very happy that fairness and reason has prevailed and the ERC has backtracked on this. Thanks to everyone who signed the open letter to the ERC for making this happen 🙏🏻 www.thetransmitter.org/policy/europ...

So I (well Claude mostly) made a @julialang.org port of the ZETA test originally developped by Jorrit Montijn (published here: elifesciences.org/articles/71969). The port is faithful to zetapy (Python version by @guidomeijer.com and @alexanderheimel.bsky.social). Enjoy github.com/PierreLeMerr...

🧠Introducing OmniMouse: One of the largest datasets in neuroscience along with a systematic study of scaling properties of brain models Co-led by 🤩 K. Willeke, @pollytur.bsky.social and @alexrgil14.bsky.social Models trained on up to 3M neurons, >150B tokens

Job alert! We are seeking a rodent in vivo electrophysiologist to work on coordination between anterior thalamus and hippocampus in rats using Neuropixels. Beautiful Scotland, leading university (Glasgow) and vibrant intellectual setting. Post is 23 months but hopefully extensible. Details here 👇

Do you record spikes in vivo? Here are two recently recommended preprints on toolboxes for extracellular electrophysiology: -MLIB doi.org/10.1101/2025... by Maik Stüttgen. -Power Pixels doi.org/10.1101/2025... by @guidomeijer.com and @battaglialab.bsky.social.

The ERC is changing the rules retroactively! A "B" grade now carries a 2-year timeout instead of 1, even for those who submitted under the old rules. Researchers (incl me) make massive career decisions based on these timelines, you can't change them after the fact 😵‍💫 erc.europa.eu/news-events/...

The Power Pixels ⚡ pipeline is out now in Peer Community Journal! Are you doing Neuropixel recordings but don't have a pre-processing pipeline yet? Check out this end-to-end pipeline designed to simplify preprocessing of Neuropixel recordings 🧠 peercommunityjournal.org/articles/10....

Main postdoc study out! We can redefine prefrontal cortex regions with single-unit activity! Grateful to @carlenlab.bsky.social and @weltgeischt.bsky.social who made this crazy project real. Thanks to all co-authors, collaborators, and reviewers. www.nature.com/articles/s41...

fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:

The Power Pixels pipeline just keeps getting better! The latest update comes with: - OpenEphys support - AP_Histology support - automatic high-frequency noise reduction - NWB format export option - zarr compression of raw data And, most importantly: a cool new logo! github.com/NeuroNetMem/...

Halloween isn’t my thing. My idea of a scary night is reading the plots of horror movies on Wikipedia.

I never understood why everyone always complains about the clocks changing. Then I had a kid.

Want to make publication-ready figures come straight from Python without having to do any manual editing? Are you fed up with axes labels being unreadable during your presentations? Follow this short tutorial including code examples! 👇🧵

I was doing the second-to-last recording of my project and was happily thinking to myself that I haven't broken a single Neuropixel in the entire two year project. You can guess what happened next... Now I have to install a new probe just for one final recording 🙃

I love how they came up with all this random stuff but for this one area they were like "I really don't know, just put a question mark"

When I told my dad I published in Nature he was like "wow, you must have made a lot of money with that"

I don't know why people say X is going down the drain, my last post got lovely replies like this one:

Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

If you're into podcasts, here's a good one on the @intlbrainlab.bsky.social brainwide map, by @newscientist.com www.newscientist.com/podcasts/fir...

Sad day for peope who still believe brain areas are the primary organizational units of function in the brain. www.nature.com/articles/s41...

The ‪@intlbrainlab.bsky.social published 2 papers today on their work to create a map of neural activity across the entire mouse brain. Learn more about the lab: https://www.simonsfoundation.org/2025/02/20/how-do-our-brains-make-decisions-the-international-brain-laboratory-is-closing-in-on-answers/

The first complete activity map of a mammalian brain has revealed unprecedented insights into how decisions are made – and may even hint at the roots of intuition.

Extremely proud to have contributed to this monumental effort of recording the entire mouse brain, at cellular resolution, during complex behavior 🧠🐭

PSA: don't buy duragel from Cambridge Neurotech, it's a scam! 🚨 They charge $200 (incl. shipping) for a 16 ml spout. But duragel is just DOWSIL 3-4680 (see paper below) of which you can buy a large container of 210 ml for only $110. That's 24 times cheaper! 💸 www.sciencedirect.com/science/arti...

Duct tape and hope are literally the only two things holding my rig together

Don't feel like reading? Check out my talk! www.youtube.com/watch?v=QIl6...

🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...

Was watching Clarkson's Farm and kept wondering how AI was going to help them get calves only to realize it stands for artificial insemination

Just added Bombcell 💣 to the suite of automatic curation tools that's included in the Power Pixels pipeline! It runs Bombcell, UnitRefine and the IBL algorithm to classify which of your units are good single neurons. You can can then use one (or more!) of these to filter your units before analysis.

🚀 We are excited to share that bombcell is now available in Python! 🐍 Automatically sort your units into good/MUA/noise/non-somatic using quality metrics and interpretable & adjustable classification thresholds. pip install and play around with our toy dataset: 🔗 github.com/Julie-Fabre/...

Do you do Neuropixel recordings and are you struggling with preprocessing? The Power Pixels pipeline is an easy-to-use pipeline from raw data to neural activity of single neurons in specified brain regions 🧠 Now on bioRxiv! www.biorxiv.org/content/10.1...

My daughter can now understand two words! When I say "clap" she claps her hands and when I say "shake" she shakes her head. Ten months of development and she's reached the level of intelligence of a dog.

Officially announcing my new game: GARBAGE COUNTRY. A lonely road trip through the ruins of a forgotten world. feat. vast wastelands, tower-defense battles, upgrades, mysteries, & lots of driving.

Oh wow. Starting grant 0-10 years post PhD from 2027, Consolidator 5-15

🚀 Datoviz v0.3 is out! High-performance GPU rendering for scientific data visualization, now with a Pythonic API, 2D axes, and improved docs & gallery. 🔗 datoviz.org 🐍 pip install datoviz #dataviz #vulkan #python #gpu #opensource #neuro #sciViz

I don't want to brag but my 9 month old baby already speaks two languages. She can say yes in Russian ("da") and grandfather in Hindi ("dada").

On my way to New York for the @intlbrainlab.bsky.social annual meeting! Luckily, as a new father, the concept of jetlag doesn't apply to me anymore.

The lab's latest published project lead by our recently graduated Dr. Rhiannon Robke! --> Optogenetic stimulation of novel TPH2-Cre rats advances insight into serotonin’s role in locomotion, reinforcement, and compulsivity (www.jneurosci.org/content/earl...).

My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour. Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org

My theory is that our universe, and everything in it, is a computer simulation made by a highschool student of some advanced civilization. Not even a particularly bright one. He hard coded that nothing can go faster than the speed of light just because it would make the math more complicated. (1/2)

Only now I have a baby do I realize it's pretty crazy we have predators with sharp claws and teeth just chilling in our homes.

The PhD students started writing motivational quotes on the whiteboard

Kilosort4 detects a LOT of neurons, I recorded 15k neurons in one year 🤯 Traditionally, one would curate these detected units to see if they are well isolated single neurons. This is not feasible anymore, so today let's look at three options that are out there to automate this process! 🤖👇

Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...