Pierre Vanderhaeghen
@vanderhaeghenp2.bsky.social
📤 1633
📥 565
📝 26
Neuroscientist at VIB KULeuven
Very insipring work from Magdalena Gotz lab - Nuclear proteome reveals microtubule-associated protein regulating fate and disease: Cell
www.cell.com/cell/fulltex...
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Nuclear proteome reveals microtubule-associated protein regulating fate and disease
Nuclear and cytoplasmic proteomics uncover a nuclear pool of cytoskeletal proteins, including MAP1B, whose shuttling to the nucleus increases BRG1/BAF chromatin association and regulates brain develop...
https://www.cell.com/cell/fulltext/S0092-8674%2826%2900578-7
10 days ago
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Last days before registration and abstract submission! Come join us in beautiful Leuven in the Fall for an amazing meeting on Synapse development and function!
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16 days ago
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thank you
@blibep.bsky.social
Baptiste ! And thank you so much for your fantastic work with us!
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16 days ago
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reposted by
Pierre Vanderhaeghen
James Briscoe
17 days ago
In our latest editorial
@amjeve.uk
& I take on the dreaded impact factor Like Monday mornings no one likes them but you can't ignore them & they keep coming around However there are things we should all do as authors, reviewers & editors
journals.biologists.com/dev/article/...
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The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
https://journals.biologists.com/dev/article/153/12/dev205838/371997/The-elephant-in-the-room-impact-factor
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reposted by
Pierre Vanderhaeghen
Molly Przeworski
27 days ago
Now published:
journals.plos.org/plosbiology/...
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We are excited to announce the 10th edition of the European Synapse Meeting
#EUSYN2026
, in Leuven from October 21-23, 2026. Abstract submission closes on June 23rd!
www.vibconferences.be/events/europ...
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European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
https://www.vibconferences.be/events/european-synapse-meeting-2026
27 days ago
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reposted by
Pierre Vanderhaeghen
Lopez-Bendito Lab
about 2 months ago
Get ready for
#SPONT26
! 🚀 Our official website is up and running. Check out the program and join us for the latest on spontaneous brain activity.
spont2026.umin.ne.jp
@guillelbendito.bsky.social
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Nice findings on the evolution of cortical cells. Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells: Current Biology
www.cell.com/current-biol...
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Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells
Gumnit et al. reveal that Cajal-Retzius cells are ancestral to jawed vertebrates. Cajal-Retzius cells share a core transcription factor identity and are evolutionarily related to a population of olfac...
https://www.cell.com/current-biology/fulltext/S0960-9822%2826%2900430-6
2 months ago
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Please read open letter and consider to share & sign - ERC matters! - see below
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2 months ago
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reposted by
Pierre Vanderhaeghen
Stein Aerts
3 months ago
We launched a new Group Leader vacancy in our Center for AI & Computational Biology - VIB.AI
@vibai.bsky.social
- with a Professorship at Ghent University. Join us with your most creative AI+Biology research plan! Apply before 31st May
vib.ai/en/group-lea...
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Group leader vacancy
We are looking for a Group Leader in applied artificial intelligence in (bio)medical research at VIB.AI & UGent, Belgium
https://vib.ai/en/group-leader-vacancy
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reposted by
Pierre Vanderhaeghen
allen institute
3 months ago
Applications are open for the Lake Conference on Comparative and Evolutionary Neurobiology - co-hosted with Circuit Neuroscience Basel! 🗓️ Oct. 25-29, 2026 📍 Seattle, WA 🧠All career stages welcomed. 🔗
https://alleninstitute.org/events/lake-conference-comparative-and-evolutionary-neurobiology-2026/
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reposted by
Pierre Vanderhaeghen
Franck Polleux
4 months ago
very exciting meeting !👇
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EuroSynapse 2026 This Fall in Leuven with Eunjoon Kim Nathalie Rochefort Bea Rico Ed Lein
@franckp.bsky.social
@cecilecharrier.bsky.social
@bellonec.bsky.social
@blibep.bsky.social
@fekrijeselimi.bsky.social
@fan-liu.bsky.social
@pouchelon.bsky.social
and more!
www.vibconferences.be/events/europ...
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European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
https://www.vibconferences.be/events/european-synapse-meeting-2026
4 months ago
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reposted by
Pierre Vanderhaeghen
Esther Klingler
4 months ago
📣 Registrations are open for the next European Synapse Meeting, taking place in Leuven from 21–23 October 2026! With
@synapse-lab.bsky.social
,
@vanderhaeghenp2.bsky.social
, LynetteLim and MarinkaBrouwer, we’ve put together an exciting program—take a look here:
www.vibconferences.be/events/europ...
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European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
https://www.vibconferences.be/events/european-synapse-meeting-2026
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Should go without saying, but saying so becomes urgent: New approach methodologies: Don’t throw the baby out with the bathwater: Cell Metabolism
www.cell.com/cell-metabol...
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New approach methodologies: Don’t throw the baby out with the bathwater
The NIH has recently called for expanding use of new approach methodologies (NAMs) to reduce use of animals in research. Arany discusses the need not to forget the irreplaceable aspects of animal rese...
https://www.cell.com/cell-metabolism/fulltext/S1550-4131%2826%2900009-4
4 months ago
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reposted by
Pierre Vanderhaeghen
Carl Zimmer
5 months ago
Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder)
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www.thetransmitter.org/animal-model...
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Neuroscience has a species problem
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.
https://www.thetransmitter.org/animal-models/neuroscience-has-a-species-problem/
5 months ago
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reposted by
Pierre Vanderhaeghen
Zebrafish Rock!
5 months ago
Published 30 years ago, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the NĂĽsslein-Volhard Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described.
#ZebrafishFunFacts
đź§Ş
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reposted by
Pierre Vanderhaeghen
EMBO
5 months ago
Happy International Day of Women and Girls in Science! đź§Ş Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award. Deadline: 15 May Read more:
https://www.embo.org/the-embo-communities/febsembo-women-in-science-awardees/nominate-for-the-women-in-science-award/
#WomenInScience
#award
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reposted by
Pierre Vanderhaeghen
6 months ago
Décès de Jean Rossier, Président passionné de Parole et Musique :
www.olyrix.com/articles/act...
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Décès de Jean Rossier, Président passionné de Parole et Musique
L’actualité de l’opéra : Décès de Jean Rossier, Président passionné de Parole et Musique
https://www.olyrix.com/articles/actu-des-artistes/8754/deces-de-jean-rossier-president-passionne-de-parole-et-musique
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reposted by
Pierre Vanderhaeghen
James Briscoe
6 months ago
There's still time to apply to be a 2026
@dev-journal.bsky.social
Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking
journals.biologists.com/dev/pages/pi...
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Pathway to Independence programme | Development | The Company of Biologists
Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...
https://journals.biologists.com/dev/pages/pifellows
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Book the dates Oct 21-23 2026 of upcoming exciting eurosynapse meeting in Leuven!
www.vibconferences.be/events/europ...
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European Synapse Meeting 2026
21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences
https://www.vibconferences.be/events/european-synapse-meeting-2026
6 months ago
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reposted by
Pierre Vanderhaeghen
Lake Conferences
6 months ago
Join us this May to explore the biological mechanisms of mental health challenges and treatment strategies. Apply by January 31:
lakeconferences.org
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Home - Lake Conferences
https://lakeconferences.org
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reposted by
Pierre Vanderhaeghen
VIB-KU Leuven Center for Neuroscience
6 months ago
🎉 Proud moment for our Center Pierre Vanderhaeghen received the 2025 Fyssen Foundation International Prize, also awarded this year to Franck Polleux (
@columbiauniversity.bsky.social
) for work on the neurobiological foundations of human cognition. 🧠🏆 Congratulations!
#FyssenPrize
#Neuroscience
#VIB
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reposted by
Pierre Vanderhaeghen
Franck Polleux
7 months ago
Delighted to be awarded the 2025 International Prize from the
@fondationfyssen.bsky.social
jointly with my long time collaborator
@vanderhaeghenp2.bsky.social
for our work on the 'Neurobiological foundations of human cognition':
www.fondationfyssen.fr/deux-laureat...
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Prix international 2025 - International Prize 2025 - fyssen
Deux lauréats pour le Prix international de la Fondation Fyssen La Fondation Fyssen a le plaisir d’annoncer que le Prix international est exceptionnellement attribué à deux lauréats cette année. Le pr...
https://www.fondationfyssen.fr/deux-laureats-pour-le-prix-international-de-la-fondation-fyssen/
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reposted by
Pierre Vanderhaeghen
Fondation Fyssen
7 months ago
La Fondation Fyssen a le plaisir d’annoncer que le Prix international 2025, consacré au thème « Fondements neurobiologiques de la cognition humaine », est attribué à Franck Polleux et Pierre Vanderhaeghen.
@franckp.bsky.social
@vanderhaeghenp2.bsky.social
Rdv en juin 2026 pour la remise de prix !
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Please check out and RT this new position for an exciting collaborative project with
@boninlab.bsky.social
and
@franckp.bsky.social
on the links between human-specific mechanisms and neurodevelopmental disorders in cortical circuits.
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7 months ago
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reposted by
Pierre Vanderhaeghen
Vincent Bonin
7 months ago
Please repost widely.
@vanderhaeghenp2.bsky.social
and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP
jobs.vib.be/j/119852/pos...
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Postdoctoral Fellow / PhD Student in Systems Neuroscience - VIB
The Laboratory of Cortical Information Processing | Vision to Action at NERF (www.nerf.be) invites applications for a Postdoctoral Fellow or PhD Student to work on a new research project funded by the...
https://jobs.vib.be/j/119852/postdoctoral-fellow-phd-student-in-systems-neuroscience
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Nice cover of our work linking SRGAP2/SYNGAP1 synaptic neoteny and ID/ASD with
@blibep.bsky.social
@benvermaercke.bsky.social
@franckp.bsky.social
@boninlab.bsky.social
@cecilecharrier.bsky.social
www.thetransmitter.org/spectrum/pro...
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Protein tug-of-war controls pace of synaptic development, sets human brains apart
Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.
https://www.thetransmitter.org/spectrum/protein-tug-of-war-controls-pace-of-synaptic-development-sets-human-brains-apart/
8 months ago
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reposted by
Pierre Vanderhaeghen
James Briscoe
9 months ago
Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
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Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
https://www.magd.cam.ac.uk/news/professor-sir-john-gurdon-frs-1933-2025
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reposted by
Pierre Vanderhaeghen
Noonan Lab
10 months ago
Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread đź§µ:
www.cell.com/cell-genomic...
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Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...
https://www.cell.com/cell-genomics/fulltext/S2666-979X(25)00242-3
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New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio:
@ryo2iwata.bsky.social
, Isabel Gallego,
@emirerkol.bsky.social
, together with
@steinaerts.bsky.social
,
@fendtlab.bsky.social
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Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...
https://www.biorxiv.org/content/10.1101/2025.08.27.672586v1
10 months ago
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Beautiful and inspiring work from Gero Miesenböck and colleagues
www.nature.com/articles/s41...
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Mitochondrial origins of the pressure to sleep - Nature
Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
https://www.nature.com/articles/s41586-025-09261-y?WT.ec_id=NATURE-202507
11 months ago
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reposted by
Pierre Vanderhaeghen
Teresa Rayon
about 1 year ago
May has been quite the month… The
#EvoDevoConference
was a blast đź’Ą Thanks to all participants and organizers for your engagement!
@mdiazcuadros.bsky.social
@bassemh.bsky.social
@vanderhaeghenp2.bsky.social
📸 (1/2)
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reposted by
Pierre Vanderhaeghen
Dmitri Petrov
about 1 year ago
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did!
www.philanthropy.cam.ac.uk/give-to-camb...
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Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
https://www.philanthropy.cam.ac.uk/give-to-cambridge/physiology-development-and-neuroscience/drosophila-genetic-database
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reposted by
Pierre Vanderhaeghen
Bassem Hassan
about 1 year ago
Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010
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Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
https://rdcu.be/ek010
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wonderful - congratulations
@debbysilver.bsky.social
!!
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about 1 year ago
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Fantastic opportunity for neuroscience research. The ROGER DE SPOELBERCH Prize for a basic or clinical research project in the areas of neurodegenerative diseases or psychiatric disorders. 750.000 EUR - Deadline JUNE 30 2025.
www.fondation-roger-de-spoelberch.ch/en/roger-de-...
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ROGER DE SPOELBERCH Prize | Fondation ROGER DE SPOELBERCH
Each year, the Foundation awards the ROGER DE SPOELBERCH Prize to a laureate for a clinical or fundamental scientific research project in the field of neurodegenerative diseases and certain psychiatri...
https://www.fondation-roger-de-spoelberch.ch/en/roger-de-spoelberch-prize/
about 1 year ago
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reposted by
Pierre Vanderhaeghen
Pedro J. Goncalves
about 1 year ago
Fantastic PhD opportunities at the intersection of machine learning and biology. Come join us at
@vibai.bsky.social
! More details at:
vib.ai/en/vibai-int...
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VIB.AI International PhD Call 2025
The VIB.AI International PhD Call 2025 is now open. We invite applicants from around the world to join an interdisciplinary research environment at the interface of AI, computational biology, and life...
https://vib.ai/en/vibai-international-phd-call-2025
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reposted by
Pierre Vanderhaeghen
Angelika Harbauer
about 1 year ago
Join us in Engelberg, Switzerland, for an exciting
#EMBO
workshop on
#mitochondria
in the nervous system
#EMBOmitoNervousSys
! Great speaker line up and opportunities for short talks from early career scientists. Submit your abstract until May 30st!
@jcourchet.bsky.social
@tatjanakleele.bsky.social
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reposted by
Pierre Vanderhaeghen
Motori Lab
about 1 year ago
I'm thrilled to be co-organizing the very first EMBO Workshop bridging mitochondria and brain research - a powerhouse of science, ideas, and amazing speakers! 🧠🔬 📅 registration closes MAY 30th, so don’t wait to snag your spot! Stay tuned - more updates about the topics and speakers coming soon! 🎙️
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reposted by
Pierre Vanderhaeghen
Patricia Nano
about 1 year ago
It’s out! The first paper from my postdoc – and first from the
@bhadurilab.bsky.social
– is now live
@natneuro.nature.com
. 🧠✨ Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
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reposted by
Pierre Vanderhaeghen
Simon Fisher
about 1 year ago
Turns out eye colour (mainly a result of iris pigmentation) is yet another complex trait, now demystified by genomic advances. DNA variants in two neighbouring genes (HERC2 & OCA2) explain much of the blue-brown variation, but analyses of ~193k people in 2021 revealed another 50 genetic loci. 👇 7/n
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Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color
A GWAS including 192,986 European and 1636 Asian participants identifies 50 novel discrete associations with eye color.
https://www.science.org/doi/10.1126/sciadv.abd1239
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Very cool study from Ikuo Suzuki lab, comparing temporal patterning in mouse and rat cerebral cortex. Non-uniform temporal scaling of neurogenesis for species-specific dosing of cortical excitatory subtypes.
www.biorxiv.org/content/bior...
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https://www.biorxiv.org/content/biorxiv/early/2025/04/10/2025.04.10.648214.full.pdf
about 1 year ago
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reposted by
Pierre Vanderhaeghen
Seth Blackshaw
about 1 year ago
Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...
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Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...
https://www.biorxiv.org/content/10.1101/2025.04.25.650540v1
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reposted by
Pierre Vanderhaeghen
Pedro J. Goncalves
about 1 year ago
Exciting project in Parkinson's disease! Patrik Verstreken's lab (
verstrekenlab.sites.vib.be
) and my lab are looking for a postdoc to develop and apply ML methods to the analysis of exciting brain-on-chip data. Please spread the word! More details at:
jobs.vib.be/j/110908/pos...
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Postdoc position: Computational methods for neurodegeneration research - VIB
About the labs The Verstreken Lab and the Gonçalves Lab are based in Leuven, Belgium and part of the
https://jobs.vib.be/j/110908/postdoc-position-computational-methods-for-neurodegeneration-research
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reposted by
Pierre Vanderhaeghen
Blanca Lorente-EcheverrĂa
over 1 year ago
Very excited to share our new preprint together with
@daniedaaboul.bsky.social
, where we studied the gene regulatory code that hippocampal granule cells (GCs) use during synapse formation (1/n)
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With beautiful illustration of calcium imaging of human cortical neurons in visual cortex of awake transplanted mice by
@benvermaercke.bsky.social
@boninlab.bsky.social
add a skeleton here at some point
about 1 year ago
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A short Perspective on xenotransplantation to study human neuron development, evolution and disease
@thetransmitter.bsky.social
More related articles on human neurobiology coming out soon - thanks a lot to Josh Sanes for the initiative and opportunity!
www.thetransmitter.org/human-neurot...
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In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
https://www.thetransmitter.org/human-neurotechnology/in-vivo-veritas-xenotransplantation-can-help-us-study-the-development-and-function-of-human-neurons-in-a-living-brain/
about 1 year ago
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