Researchers from the De Strooper Lab just revealed how #lecanemab ’s Fc fragment is key to activating microglia to clear toxic amyloid plaques. It’s the first direct mechanistic evidence for this class of Alzheimer’s therapies, published in Nature Neuroscience. Read more: tinyurl.com/44x5bxjt

Apply for our International PhD Call! Discover the 11 new projects for this edition and apply until the 20th of November. 🔗More info: cbd.sites.vib.be/en/phdcall2026

⚡ It's #TechnologyTuesday, and Suresh Kumar Poovathingal and Kristofer Davie are taking us on a whirlwind tour around the Single Cell units! 🌪️ (1/3) youtu.be/paqikg_sK5M

🏆 Bart de Strooper, M.D., Ph.D., is the recipient of the Khalid Iqbal Lifetime Achievement Award. #AAIC25 @ucl.ac.uk‬ @cbdresearch.bsky.social @ukdri.ac.uk

🌟 We warmly welcomed this scientific delegation from the KOREA-EU Research Centre! It was a fantastic opportunity to forge connections between biotechnology researchers based in South Korea and Belgium. Find out more 👉 lnkd.in/ekmNA27S

A new review from our center, published by Céline Vrancx and Wim Annaert, sheds more light into how APP-CTF toxicity could be an overlooked factor in the pursuit of preventive therapies for #Alzheimer's disease 🧠 Read it here: www.sciencedirect.com/science/arti... @cellpress.bsky.social

Last piece of work by Urban lab @viblifesciences.bsky.social @cbdresearch.bsky.social @nerflabs.bsky.social

🌟 Congratulations to the laureates of the 2025 Queen Elisabeth Medical Foundation for Neuroscience scientific awards, which include two researchers from our Center! Find out more 👉 cbd.sites.vib.be/en/news#/new...

New prize at our center! Our Liu Lab received the Outstanding Early Investigator Award, by the Sleep Research Society. This distinction was awarded to Joana Dopp, former PhD student at our center, following their publication on Nature Neuroscience. Congratulations! cbd.sites.vib.be/en/news#/new...

'RNA-binding proteins in #ALS and #FTD: from pathogenic mechanisms to therapeutic insights' Jens Rummens & Sandrine Da Cruz @cbdresearch.bsky.social #FrontotemporalDementia #TDP43 molecularneurodegeneration.biomedcentral.com/articles/10....

🌅 We warmly invite you to New Horizons in Neuroscience, a conference to explore the latest in neurodegeneration technologies, models, and treatments! 🗓️ 9-10 October, 2025 📍 Leuven, Belgium Find out more 👉 www.vibconferences.be/events/new-h...

✨ Congratulations are in order for our FWO Postdoctoral Fellows — Artemis Koumoundourou, Gemma Martinez Rivas, and Ramon Duran-Romaña! 🧠 Through FWO's support, these scientists will continue to study the fundamental mechanisms driving brain development and functioning in health and disease.

🤸‍♂️ We once again teamed up with TAJO vzw — an organization combatting early school leaving, and allowing youth from vulnerable home situations to enter society autonomously and prepared — to inspire young people to get interested in neuroscience! Find out more 👉 cbd.sites.vib.be/en/news#/new...

🐦 Early bird registrations for the TRP conference #TRP2025 — organized by the Thomas Voets Laboratory of Ion Channel Research — are now open! 📅 Save the Date: 17-19 September 2025 📍 Location: Leuven, Belgium 👉 Find out more here: lnkd.in/dwRpv_sH

📣 New research from the De Wit lab identified a 'molecular break' that regulates synaptic maturation and function. These new findings show how two different proteins — GPR158 and PLCXD2 — interact to form the spine apparatus in developing synapses. Find out more 👉 cbd.sites.vib.be/en/news#/new...

🤸 This year's Science Day was as energizing, inspiring, and fun as ever! We teamed up with @nerflabs.bsky.social — another @viblifesciences.bsky.social neuroscience research center, who became our neighbors on the Gasthuisberg campus this year — and enjoyed arguably the best Science Day yet.

🚀 #WeAreHiring! The Verstreken and Goncalves labs are looking for a postdoctoral researcher to investigate computational methods for neurodegeneration research ⤵️ Apply now 👉 lnkd.in/e4Huym6t (1/5)

🌟 We welcome João Cardoso, who joined Bethan Burnside in the science communication team at the VIB-KU Leuven Cenrter for Brain & Disease Research this month! Find out more about communication, outreach and engagement initiatives at our center and get in touch 👉 cbd.sites.vib.be/en/engagement

⚡ It's #TechnologyTuesday, and this week Nicolas Poulvellarie is taking us for a tour around the Neuroengineering unit! 🤖 (1/3) www.youtube.com/watch?v=RZ3o...

🌟 New research from the Lucia Chavez Gutierrez lab unravels the genetic contributions to familial Alzheimer’s disease development and reveals how specific mutations act as a clock to predict the disease age of onset ⏰ Find out more 👉 lnkd.in/eAd4rwcp Read the paper 👉 lnkd.in/ePDE2hVQ

📣 New review from the Ludo Van Den Bosch lab on lipid metabolism alterations in peripheral neuropathies published in Neuron! Read the review 👉 lnkd.in/e2MHz8xN Find out more about Alessio’s research on lipid metabolism alterations and ferroptosis in CMT1A 👉 lnkd.in/eUXyTrC5

⚡ This #TechnologyTuesday, we're being taken around the VIB Metabolomics Core Leuven with Bart Ghesquière, Camila Cologna and Pedro Magalhães! ✨ #metabolomics #proteomics #massspectrometry #biology #neuroscience #brain #research www.youtube.com/watch?v=EZuA...

🌟 A very special #FluorescentFriday this week featuring the winners of the annual VIB Bioimaging Core competition! 🤩 🔬 #neuroscience #microscopy #brain #bioimaging

🚀 New study reveals how four different anti-amyloid drugs interact with amyloid beta protein. They found that lecanemab performed best in binding to small oligomeric forms of the amyloid protein, suggesting a working model for treating people in the earlier stages of Alzheimer’s (1/4)

📣 Looking for binf master students ! @cbdresearch.bsky.social @kuleuven.bsky.social @kuleuvenuniversity.bsky.social klinglerlab.org

In a recent study from the Da Cruz Lab @cbdresearch.bsky.social, Jens Rummens et al. used image-based FACS on the S8 to distinguish cells with or without TDP-43 aggregates. @vibflowcore-lv.bsky.social Congrats to the entire team! 👏 Link to the paper: https://doi.org/10.1016/j.neuron.2025.03.004

🌟 We celebrate Annerieke Sierksma who was awarded the Miet Smet Prize for her achievements in Alzheimer’s disease research. This award not only honors her contributions to understanding neurodegeneration but also serves as a tribute to Miet Smet, a trailblazer for women's rights 👩‍🔬

⚡ This #TechnologyTuesday, we join Jochen Lamote for tour around the VIB Flow Cytometry Core in Leuven! 🌀 www.youtube.com/watch?v=1fTh...

🏃‍♀️‍➡️ Support Researchers Running for Alzheimer's! For the second time this year, we're teaming up with Stichting Alzheimer Onderzoek (SAO) to raise awareness and funds for Alzheimer's research through a sponsored run 💜 (1/4)

⚡ It's #TechnologyTuesday, and this week Keimpe Wierda Weirda is taking us around for a tour of the Electrophysiology Unit! 👨‍🔬 (1/3) www.youtube.com/watch?v=mEhk... ✨ #biophysics #biology #neuroscience #brain #research

📣 Scientists led by Sandrine Da Cruz have successfully seeded the accumulation of TDP-43—a hallmark of ALS and frontotemporal dementia—using lab-engineered protein fragments 🧠🔬 Find out more 👉 cbd.sites.vib.be/en/news#/new...

🤸‍♀️ We invite you to join this course on Molecular Neurodegeneration and Therapeutic Approaches, which includes Patrik Verstreken as an instructor! 🧬 Find out more and apply 👇 coursesandconferences.wellcomeconnectingscience.org/event/molecu...

⚡ It's #TechnologyTuesday, and to kick-start the series we have a tour of the VIB Bioimaging Core by Pablo Hernández-Varas! 🔬 (1/4) www.youtube.com/watch?v=hKUy...

✨ Congratulations to the researchers who received a grant from Stichting Alzheimer Onderzoek (SAO) to fund projects with a focus on Alzheimer's disease. Find out more 👉 cbd.sites.vib.be/en/news#/new...

⚡ The Leica LMD7 laser microdissection system is one of the latest instruments to arrive at VIB. Rodrigo Gallardo, Project Leader of the BE.Amycon #GrandChallenges project, explains how the device will help tackle the diagnostic challenges of #amyloidosis (1/5)

Chelsea Hayen, a PhD student in the lab of @estherkli.bsky.social, studies how early-life stress shapes the emotional circuits of the brain 🤯🧠 (1/5)

🧠 Researchers at EARA members @vibai.bsky.social & @cbdresearch.bsky.social have used #AI, trained on human and animal data, to shed light on #BrainEvolution and how this may give clues to #BrainDiseases. www.eara.eu/post/insight...

Mooi nieuws op Dag Zeldzame Ziekten: LBI bestuurslid prof Patrik Verstreken krijgt dit jaar de Prijs Generet voor zeldzame ziekten van de Koning Boudewijn Stichting 🏆 Bekijk de infofilm hier images.app.goo.gl/xZ9z9187JH7m... Of lees erover hier kbs-frb.be/nl/1-miljoen... @cbdresearch.bsky.social

Great #incuabseminar by Dr. Anna Martínez Muriana, from @cbdresearch.bsky.social (and former NFIS researcher at our Institute!) She presented a pioneering human microglia xenotransplantation model, revealing species-specific transcriptomic and proteomic profiles.

What better way to mark two years as the Proteomics Expertise Unit Leader @cbdresearch.bsky.social than with the installation of the first Orbitrap Astral in Belgium! Eager to push the limits of this state-of-the-art MS - not only in Proteomics but also in Multiomics workflows!

🧠 #BrainAwarenessWeek aan het #LeuvenBrainInstitute 💡Gisteren werden leerlingen van het Sint-Pieterscollege Leuven ondergedompeld in de wondere wereld van het brein 🔬Lezingen door @lucasmergan.bsky.social & @eliskbv.bsky.social, demo’s door @cbdresearch.bsky.social @viblifesciences.bsky.social

🚀 Congratulations to our group leaders who received senior research project grants from the Research Foundation Flanders - FWO! • Sandrine Da Cruz • Joris de Wit • Pierre Vanderhaeghen • Esther Klingler

Scientists in the De Strooper Lab show that the role of microglia in Alzheimer's varies depending on the stage of the disease, in a new study published in Nature Communications. Find out more 👉 cbd.sites.vib.be/en/news#/news/microglia-the-double-edged-sword-in-alzheimers-progression

📣 New research from the Annaert Lab sheds light on how mutated PSEN2 accelerates disease progression in familial Alzheimer's disease! Their findings, published in Nature Communications, offer new insights into the mechanisms driving this genetic form of the disease. Article in comments 👇

⏲️ Just one day left! Apply to do a #PhD in #Neuroscience and join our vibrant and diverse research community in Leuven, Belgium! 🌍💙 11 projects available spanning #ComputationalBiology, #Neurodegeneration, #Development, #Sleep, #Pain, and much more! Apply today 👉 lnkd.in/ekijhCzy