RadfordLab
@radford-lab.bsky.social
📤 276
📥 115
📝 25
Radford Brockwell and Calabrese labs post here
reposted by
RadfordLab
Maddie Gilbert
about 2 months ago
It was graduation day on Friday! A fitting celebration for a very enjoyable cryoET PhD experience with
@drrenefrank.bsky.social
@radford-lab.bsky.social
@jenkinsjj.bsky.social
@astbury-bsl.bsky.social
and the team 🎉🎉
2
17
2
See our latest paper on BAM action. Great work to the team and super collaborations with
@naranson.bsky.social
@antoncalabrese.bsky.social
and @Jean Francois collet. Have a read
rdcu.be/eJjDp
loading . . .
Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function
Nature Communications - BamA is the catalytic core of the BAM complex, which inserts proteins into bacterial outer membranes. Here, the authors show that hinge flexibility between BamA’s...
https://rdcu.be/eJjDp
4 months ago
0
5
3
Delighted to see our new DMS of amyloid formation and predication of amyloid stability vs sequence changes out at PNAS. Brilliant work Conor!
doi.org/10.1073/pnas...
loading . . .
Employing deep mutational scanning in the Escherichia coli periplasm to decode the thermodynamic landscape for amyloid formation | PNAS
Deep mutational scanning (DMS) assays provide a powerful method to generate large-scale datasets essential for advancing AI-driven predictions in b...
https://doi.org/10.1073/pnas.2516165122
4 months ago
0
5
0
Our review on CPEB and memory published today- thanks to all authors. Enjoy the read
5 months ago
0
1
2
Delighted to see Jon Machin's lovely OMP folding and assembly work on the front cover of JMB (doi: 10.1016/j.jmb.2025.169346) and in this Faraday Discussion article (doi: 10.1039/d4fd00180). Congratulations on your great work Jonathan!
5 months ago
0
8
5
Interested in amyloid polymorphs? Our latest paper with PhD student Jack Connor is just out. Have a read and do try out his analysis on your favourite amyloid structures!
doi.org/10.1016/j.st...
6 months ago
0
7
4
Delighted to share our latest paper on OMPs and the effects of their interactions on OMP catalysis in the bacterial outer membrane. The latest super work from Jonathan Machin. See
doi.org/10.1016/j.jm...
6 months ago
1
6
3
Great day celebrating Katy Dewison’s PhD. Good luck in all you do in the future Katy in your postdoc at Aarhus. We will miss you’
6 months ago
0
7
2
Super FASEB meeting on protein misfolding and amyloid fibre polymorphs in Phoenix Arizona. Hot science and a hot place (45C)! Katy and Jack did a great job presenting their data in talks and posters.
7 months ago
0
6
1
So proud our lab was awarded Gold LEAF status for sustainability. Thanks to Nasir Khan, Tabitha Howe and
@antoncalabrese.bsky.social
for making it happen for us all! Keep up the good work!
8 months ago
0
8
1
Two prizes in one day! So proud of Maddie Gilbert and Katy Dewison who each was awarded a prize for their PhD thesis work in the Faculty of Biological Sciences on Alzheimer’s and Parkinson’s disease respectively.
8 months ago
0
10
1
reposted by
RadfordLab
Bijvoet Centre
9 months ago
Beautiful and inspiring talk by Sheena Radford of the
@radford-lab.bsky.social
at the Astbury Centre for Structural Molecular Biology (
@astbury-bsl.bsky.social
) from the University of Leeds (
@universityofleeds.bsky.social
) at our annual Bijvoet Symposium!
0
8
5
Honoured to sign the book to become an international member of the National Academy of Sciences. Proud to receive this in recognition of all the work of many group members and collaborators over the years. Thank you all.
9 months ago
0
26
1
Our commentary on flow and amyloid formation published today
www.pnas.org/doi/10.1073/pnas.2504573122
10 months ago
0
1
1
At last our paper is out at JACS and we made the front cover! Thanks to Phospho animation for the image. See
doi.org/10.1021/jacs...
.
10 months ago
0
3
3
Had a wonderful time at ADAM10 in Gothenburg with old and new friends! Thank you for a great 3 days of amyloid science.
10 months ago
0
2
0
reposted by
RadfordLab
Cláudio Gomes Lab - Protein Misfolding in Disease
11 months ago
Looking forward
#ADAM10
kick-off 🇸🇪 3 days of all things amyloid and great opportunity to meet old friends and making new ones! Thanks
@professorpernilla.bsky.social
and Elin Esbjorner et al for such a great program. Reach out if you are around
www.chalmers.se/en/conferenc...
0
6
2
reposted by
RadfordLab
Michelle Peckham
11 months ago
Just some of the amazing scientists
@universityofleeds.bsky.social
in FBS,
#international
women’s day
0
10
6
Proud to be part of this great article with
@ldaubrey.bsky.social
. Of interest to all working on amyloid polymorphs see
doi.org/10.1016/j.jmb.2025.169008
11 months ago
0
8
3
Delighted our latest paper on amyloid polymorphs is published in JACS- doi 10.1021/jacs.4c16743. Well done all- very proud!
11 months ago
1
12
5
reposted by
RadfordLab
Joel A. Crossley
12 months ago
BPS day 2!
@emilyjbyrd.bsky.social
@radford-lab.bsky.social
@biophysicalsoc.bsky.social
0
4
1
Super visit to UTSWCentre for Alzheimer and Neurodegeneration yesterday and to see Nikos Louros- a great host in a frozen and cold Dallas!
12 months ago
0
2
1
Are you interested in proteins as exciting, dynamic interacting species. Come and join our meeting on March 28th 2025. Places are limited so register ASAP (ÂŁ25 only!) at sheena-radford-lab.uk/fida.php. New news- thanks to British Biophys Soc travel bursaries will be available for ECR registrants.
about 1 year ago
0
5
3
Do come snd join our excellent meeting. All welcome for a great day of science of proteins in action. And all for ÂŁ25!! We would love to see you and our conference venue is great too!
add a skeleton here at some point
about 1 year ago
0
0
0
reposted by
RadfordLab
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025. Places are limited so please register ASAP at
sheena-radford-lab.uk/fida.php
. (ÂŁ25.00 registration only, including excellent catering).
about 1 year ago
0
4
4
reposted by
RadfordLab
Neil Gow
about 1 year ago
Brilliant talk (introduced by our VC Lisa Roberts) on the formation of a temporal series of amyloid aggregates in driving human diseases by Sheena Radford at our distinguished lecturer series.
@lsiexeter.bsky.social
a LSI / Biosciences @ Exeter.
1
3
2
reposted by
RadfordLab
Great opportunity to join the Radford / Ranson labs and the world-renowned Astbury Centre as a Research Fellow in Structural Biology! Please see
jobs.leeds.ac.uk/vacancy.aspx...
loading . . .
Job Opportunity at University of Leeds: Research Fellow in Structural Biology
Are you an ambitious researcher looking for your next challenge? Do you have an established background in structural studies of amyloid aggregates and want to help to develop new routes to combat amyl...
https://jobs.leeds.ac.uk/vacancy.aspx?ref=FBSAC1010
about 1 year ago
0
1
4
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025. Places are limited so please register ASAP at
sheena-radford-lab.uk/fida.php
. (ÂŁ25.00 registration only, including excellent catering).
about 1 year ago
0
4
4
Congratulations to Leon Willis and co-authors for getting two publications accepted recently: a review on antibody developability in Biologics and a paper where we develop an analytical workflow to assess this in Molecular Pharmaceutics. Links to both below!
www.dovepress.com/biophysical-...
loading . . .
Biophysical analysis of proteins in the early drug development pipelin | BTT
Therapeutic proteins, particularly monoclonal antibodies, have emerged as powerful medicines over the past forty years due to their potency. Read more.
https://www.dovepress.com/biophysical-analysis-of-therapeutic-antibodies-in-the-early-developmen-peer-reviewed-fulltext-article-BTT
about 1 year ago
1
2
0
Great opportunity to join the Radford / Ranson labs and the world-renowned Astbury Centre as a Research Fellow in Structural Biology! Please see
jobs.leeds.ac.uk/vacancy.aspx...
loading . . .
Job Opportunity at University of Leeds: Research Fellow in Structural Biology
Are you an ambitious researcher looking for your next challenge? Do you have an established background in structural studies of amyloid aggregates and want to help to develop new routes to combat amyl...
https://jobs.leeds.ac.uk/vacancy.aspx?ref=FBSAC1010
about 1 year ago
0
1
4
reposted by
RadfordLab
about 1 year ago
Great opportunity to join the Radford / Ranson labs and the world-renowned Astbury Centre as a Research Fellow in Structural Biology! Please see
jobs.leeds.ac.uk/vacancy.aspx...
loading . . .
Job Opportunity at University of Leeds: Research Fellow in Structural Biology
Are you an ambitious researcher looking for your next challenge? Do you have an established background in structural studies of amyloid aggregates and want to help to develop new routes to combat amyl...
https://jobs.leeds.ac.uk/vacancy.aspx?ref=FBSAC1010
0
1
3
Hello all in Bluesky. The RadfordLab and friends will be posting here so please look out for our updates. We wish you all well for 2025!
about 1 year ago
2
13
4
you reached the end!!
feeds!
log in