We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

Preprint 🧵! I’m really excited to introduce BIGSMALL, an interleaved multi-magnification cryo-ET scheme bridging molecular and cellular scales in a single acquisition! BIGSMALL = 𝐁road 𝐈nformation 𝐆athering 𝐒trategy by 𝐌ultiscale 𝐀cquisition of lame𝐋𝐋a www.biorxiv.org/content/10.6... (1/6)

We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated. mrc.tal.net/vx/appcentre...

Delighted to see Jon Machin's lovely OMP folding and assembly work on the front cover of JMB (doi: 10.1016/j.jmb.2025.169346) and in this Faraday Discussion article (doi: 10.1039/d4fd00180). Congratulations on your great work Jonathan!

Big congrats to @lola-stephens.bsky.social for finishing her DVRS placement today! She’s spent the last eight weeks diving into computational projects in the lab, getting to grips with particle picking, segmentation, and subtomogram averaging. Good luck with your final year of neuroscience!

Huge shout out to @jenkinsjj.bsky.social for his excellent talk on the #cryoET structure of Tau filaments from human brain tissue at CCPEM Spring Symposium in Nottingham! #cryo-EM @diamondlightsource.bsky.social @ccpem.bsky.social

🚨 We’re hiring! 🚨 We’re looking for a Correlative Imaging Scientist to join our EM team at ABSL! You will be developing and supporting cryo-EM & cryo-CLEM workflows across multiple imaging platforms (FIB-SEM, cryo-confocal, cryo-EM). Any questions? Get in touch! jobs.leeds.ac.uk/Vacancy.aspx...