On May the 14th, Paul Rignanese presented the Spikeling project for the first GRI-UK conference at @edinburgh-uni.bsky.social . We had insightful interactions with both scientists and families of patients affected by a GRIN mutation.

Here is a little simulation / teaser for something new coming to Open Source Neuro. Meet Spiky, a compact neuromorphic electronics implementation of a LIF / AdEx-style neuron model.

In her Nature piece “Train PhD students to be thinkers not just specialists”, Prof. @gundulaboschphd.bsky.social argues that scientific training should cultivate more than technical expertise. #Science #Neuroscience

From intracellular to extracellular, in one teaching platform. Spikeling lets students move from patch-clamp-style electrophysiology to calcium-imaging logic and extracellular tetrode recordings in a single open teaching workflow. #Neuroscience #Neurophysiology

Neuronal logic with Spikeling ! Part 3 Spikeling is a virtual spiking neuron you can patch and tune. It’s a brilliant bridge between neuroscience, boolean logic, and machine learning fundamentals. #Neuroscience #ComputationalSciences #Neurophysiology #Electrophysiology

Neuronal logic with Spikeling: part 2 In part 1, we showed how to build OR and AND gates for action potentials using excitatory synaptic gains. #Neuroscience #Neurophysiology #Electrophysiology #NeuralCircuits

Yesterday was #purpleday, the global epilepsy awareness day. Learn about mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Neuroscience #Education #Epilepsy

Neural computation emerges from physical processes in biological circuits. #Neuroscience #ComputerScience #NeuronalCircuits

Yesterday for @opensourceneuro.com , Paul Rignanese was presenting a poster and a live demo of Spikeling at the Institute for Neuroscience and Cardiovascular Research Early Career Researcher Day at the The @edinburghuni.bsky.social ! #Neuroscience #BiomedicalSciences

Spikeling v3 feature reveal : a new module ! After current clamp, voltage clamp, calcium imaging, we are implementing an extracellular tetrode recording module ! #Neuroscience #CalciumImaging

Interplay of behaviour and neurophysiology is at the core of neuroscience, and collaboration of ethologists and neurophysiologists is crutial. #Ethology #Neurophysiology

OSN promotes neuroscience access with open, low-cost tools for education, training, and outreach, especially where conventional neurophysiology setups aren’t available. #ScienceOutreach #OpenScience

Spikeling’s imaging simulation brings microscopy-grade data interpretation into the classroom by linking Vm/spikes to Ca²⁺ and fluorescence (F ; ΔF/F) in real time. #Neuroscience #CalciumImaging

State-of-the-art neuroscience education shouldn’t depend on access to patch-clamp rigs or two-photon microscopes. At the @trendcamina.bsky.social computational neuroscience & ML workshop feat. @akoumoundourou.bsky.social, students arrive with strong coding skills - #NeuroscienceEducation #CAMINA

See how we can approach the mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Epilepsy #Seizure #Neuroscience #Electrophysiology #Neurophysiology

POV : unboxing a Spikeling delivery from @opensourceneuro.com ! #Neuroscience #Education #STEM #Electrophysiology #Neurophysiology #Opensource #Spikes

Sensory neuroscience workshop with Spikeling — from light to spikes. Run meaningful sensory experiments outside the wet lab: the on-board photoreceptor provides a synaptic-like input to an in-silico patched neuron. #Neuroscience #SensoryNeuroscience

Spikeling allows to learn about neurophysiology from many angles, it is easy to see how different neuronal subtypes encode stimulus input information. #Neuroscience #Education #Teaching #InformationTheory

See how easy it is to plug and play with a buzzing Spikeling. This is just a teaser, follow us for more demos of the numerous cool functionalities and applications of Spikeling ! #Neuroscience #Electrophysiology #Teaching #Education

Last week @opensourceneuro.com was at Université Côte d'Azur for a Spikeling demo. Thanks to the Molecular and Cellular Pharmacology Institute affiliated with CNRS-INSERM for the invite ! #Spikeling #Neuroscience #Education

Spikeling is an open-source teaching device built to democratize neurophysiology education. In academia—especially in low-resource and low-income settings—hands-on electrophysiology is often limited by cost and logistics. #OpenScience #OpenHardware #NeuroscienceEducation

With a Spikeling board and the GUI, students have a hands-on interface to run patching ephys experiments with custom stimuli on a variety of neuronal subtypes. It is super intuitive, check this short video demo ! #Neuroscience #Education #OpenSource #Electrophysiology

I’ve been using Spikeling in teaching and outreach for the past 4 years, and it’s been a really effective way to make neuroscience concepts more approachable and engaging. Hands-on tools like this really help move neuroscience teaching forward 🧠⚡ Have a look 👇

For this new year, we are proud to announce the launch of Spikeling v3 ! Spikeling is an Open-Source neuroscience education platform that brings a patch-clamp-style electrophysiology workflow into the classroom. #Neuroscience #OpenScience #OpenHardware #Education

📌 Application deadline approaching! This is the final week with only 6 days left before the #TReNDCaMinA application deadline. If you haven’t submitted yet, now is the time; don’t wait until the final hours. #ComputationalNeuroscience #Machinelearning