What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope! Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals. Read the paper here: www.science.org/doi/10.1126/... (1/10)

Trans rights are human rights. Fresh work incoming: Here we quantitatively compare the representational geometry of mouse CA1 and human spatial memory during environmental deformations. Briefest TLDR: Human memory looks like a change-resistant version of mouse CA1. www.biorxiv.org/cgi/content/...

Gotta make sure your results generalize to mascots! #uic

Super excited to share that one of our outstanding founding undergrad RAs @dahery.bsky.social will be headed to the Kempner postbac program at Harvard to work with @gershbrain.bsky.social after graduation! Congratulations David! You cannot be replaced, and I’m so proud and excited for you!

The dataset and code for our recent paper in Neuron (tinyurl.com/yc48d6vr) is online now! The data is available on Zenodo (zenodo.org/records/1486...) and code on Github (github.com/jquinnlee/ge...). Big thanks to @markbrandonlab.bsky.social and @atkeinath.bsky.social on this effort! #neuroskyence 🧠

How good is your place cell model? Come benchmark yours against real data - nearly 70K CA1 rate maps in various geometric shapes across weeks - collected and curated in my lab by the great @jquinnlee.bsky.social and @atkeinath.bsky.social

If you’ve been wondering what Elon Musk and his lackeys are up to since taking control of the US government, look no further. Our latest story names six 19- to 24-year-olds working with his DOGE organization, which now has access to sensitive federal systems. wrd.cm/4jzpiSN

Shoutout to all the millennial junior faculty who finally got their dream jobs right as the scientific enterprise in the states is functionally dismantled.

i think an important thing for people outside the US to understand is that elon musk seized control of the government today and most americans don’t even realize it happened.

The campaign against trans rights is also about stripping away everyone’s protections against discrimination, reviving, as Douglass put it “the moral blindness” of those who “persuade themselves that they are safe, though the rights of others may be struck down.” www.theatlantic.com/ideas/archiv...

🚨 new publication from our lab in @pnas.org ! "Expert navigators deploy rational complexity–based decision precaching for large-scale real-world planning" Entropy of streets & successor representations explain planning speed Colab wth Daniel McNamee at Champalimaud www.pnas.org/doi/10.1073/...

Trump is attempting to unilaterally freeze trillions of dollars in federal spending that’s been duly appropriated by Congress. This is completely insane and illegal. He’s seizing unlawful control over the constitutional spending power? Five alarm fire www.washingtonpost.com/business/202...

RFkJr is a threat to human health: when the next pandemic hits we need disease tracking (CDC now silenced) and fast vaccine development (which he opposes). If you live in ME, NC, SD, LA, AK, ID, KY or SD call your senators to oppose his confirmation (hearing this Wed.). (continued, please retweet):

This is a very scary time for early career scientists like people looking for/who are postdocs and new faculty trying to get funding. Any words of encouragement to share for people in this category?

Okay, this is very cool: evidence from Peter Jonas' group that human CA3 follows a different logic of synaptic connectivity than rodent CA3, focussing more on sparser, but highly reliable synapses. www.cell.com/cell/fulltex... CC @dlevenstein.bsky.social & @repromancer.bsky.social #neuroscience 🧪

Tough week to be a trans neuroscientist with an immigrant spouse in the US… … anyway, see y’all at Winter Brain!

Out now in Nature from @behrenstimb.bsky.social and crew: www.nature.com/articles/s41... Understanding this kind of schematic pattern learning and transfer will be key, IMO, to moving towards models of what we might call "higher-order cognition" or "reasoning". 🧠📈 🧪

Our latest preprint has landed www.biorxiv.org/content/10.1... Fantastic work from @laurenb29.bsky.social and Will de Cothi showing how many of the cell types associated with subiculum (e.g. boundary vector cells, corner cells) can be understood as successor features. TLDR: SUB not CA1 is the SR

Super excited to share our first preprint of work from the lab! We monitor and manipulate the CA1 representation of mice exploring a multicompartment environment to contrast geometric vs. predictive theories of cognitive mapping. TLDR: All signs point to a predictive theory! tinyurl.com/yeyv5p3x

Just in time for Thanksgiving, we're grateful for the publication of our paper in #eLife doi.org/10.7554/eLif... We measured dopamine and behavioral responses to intraorally delivered sucrose across acquisition and extinction of a conditioned taste aversion. 1/n

Psyched that my postdoc work w @markbrandonlab.bsky.social + @atkeinath.bsky.social is now in Neuron! TL/DR: remapping in CA1 has a representational structure that is reliable across brains, and we use this representation to test models of cognitive maps. #NeuroSky #NeuroAI 🧪🧠 tinyurl.com/4juhmad8

My last postdoc pub with @markbrandonlab.bsky.social and @jquinnlee.bsky.social is out. Here we use RSA and miniscopes to characterize CA1 responses to diverse deformations and compare to models. The dataset is public, and we'll build on it in future work. authors.elsevier.com/c/1k8j8_KOmx...

Exciting day for us at the Keinath Lab! Last day of data collection for our first set of immersive VR experiments. 300+ participants across three experiments, this last one in an extra-large space! Stay tuned!