🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

We have developed a new workflow to map whole human organs at single-cell resolution, while integrating spatial transcriptomics, proteomics, and metabolomics. We applied this workflow to map precancerous lesions of the fallopian tubes. More here: www.biorxiv.org/content/10.1...

Resharing with ALT

Nothing to add.

Sharing my own pretty image on #ZebrafishZunday! #devbio

Do you remember The twenty deadlines Of September

I refer to clams as a cross between a cow and a vacuum cleaner. And like a cow, some species of clams fart out a fair bit of methane! Their farts may account for ~10% of methane released in some environments. So to answer a question I'm sure many of you have, yes, clams fart. (261)

They are hiding something... Slingjaw Wrasse. #LetsChangeThat

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

this is wild - i was aware of Mary-Claire King's absurdly important discoveries on BRCA / inherited breast cancer but I had no idea that her first PhD paper (King & Wilson 1975, Science, not bad lol) is the "99% of protein coding shared btwn chimps and humans" result www.science.org/doi/abs/10.1...

"Shinji, we're going to need you to do another single-cell experiment or Rei will have to" youtu.be/fShlVhCfHig?...

Happy to share these gorgeous images of a chicken neural tube with fiery green, orange, and blue microtubules and explanted #NeuralCrest cells with green actin and pink microtubules taken by Camilo Echeverria on this #FluorescenceFriday. #DevBio @ucdavis.bsky.social @ucdavisvetmed.bsky.social

Tl;dr = No. www.science.org/content/blog...

It's #FluorescenceFriday! Another movie from our preprint, showing exocytosis of VAMP2-pHluorin (live-cell TIRF, blue) correlated with 2-color STORM of spectrins (green) and clathrin-coated pits (magenta). www.biorxiv.org/content/10.1...

Congrats to @errricpeterman.bsky.social on leading our latest paper now published in @jcellsci.bsky.social ! Eric found multiple roles for microtubules in tissue-resident macrophage homeostasis and function -- including in helping macrophages navigate around epithelial obstacles during wound repair👇

imagine relying on AI to write your bio and then having the nerve to say you're witty and full of personality

I am a promoter truther now. Only mammals have promoters. Other animals, such as fishes, use a Rube Goldberg machine

Were the reviewers asleep orrrrr.....? 🧪

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

The idea that the combined MMR is dangerous but separately the vaccines are fine was created out of whole cloth by Andrew Wakefield, a disgraced former doctor who had a patent on a non-combined version of the MMR. We've known his research was bunk for almost 30 years.

bioRxiv partners with Dryad to enable easier, better linking to curated datasets connect.biorxiv.org/news/2025/09...

Your Honor, they were not wearing gloves while grabbing the tube

Check out the latest President's Corner by SDB President Richard Behringer @rrbehringer.bsky.social on challenges. www.sdbonline.org/resource?Res...

Florence Pugh speaks up at the "Together for Palestine" fundraiser: "Silence in the face of such suffering is not neutrality, it is complicity. Pressure on the governments."

Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪 A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today! #InHoxWeTrust

Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1... Read the thread below for a summary of our findings 🧵1/11

Science: only when you write up the manuscript, you realize what you should have done.

u know who are skeptics scientists are skeptics being anti-science is not being a skeptic

Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information: 🔗 doi.org/10.1101/2025...

The News Splash is out! www.izfs.org/newssplash/n.... With a review of this summer’s IZFC, profiles of award winners, and Science Spotlight articles covering recent zebrafish research. Also an alternative career profile (medical writing) and updated news on international shipping of zebrafish lines.

This is the equivalent of Jesus on a toast for developmental biologists 🧪

'Memento', but it's every plot you make in R

me to my students: LLMs are like your worst ex. They will LIE to you with the most serene, most confident face one of my students, quietly: I hate that guy so much

This is the equivalent of Jesus on a toast for developmental biologists 🧪

This is huge.

Every artist I’ve ever known has this itch to create that won’t go away until they create. They have to do it. It’s why I know the “finally, someone like me can make art” AI users are full of shit. What they really mean is “finally, a way to get social media likes without hard work”.

The Company of Biologists and the British Society for Developmental Biology: a model partnership As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social doi.org/10.1242/dev....

Parents *shouldn't have to* lead the way in helping kids navigate AI risks and opportunities. Parents should be able to trust that developers and regulators are working to ensure that AI is safe and ethical, and that educators are trained to help kids navigate these tools responsibly. 1/

My review of the evidence (morphological, embryological and molecular) for the deuterostomes clade is now available. www.annualreviews.org/content/jour...

I *hate* when someone sends me a plasmid and I have to triple guess (a) what they blotted, (b) how they blotted it, (c) what the backbone and resistance may be, and (d) why they've stopped replying to my emails asking about all these details. I have tried this four times.

I dedicate this one to the one and only --the hottest confirmed entity in the observable universe- @reddiesteadygo.bsky.social

Its just the enshittification of research: cash out by squeezing out all possible value without investing in the long term.

I find it asinine that we're being told over and over again that there's possibly no money (dramatic pause) but then there's magically money to attract people to a system that has no money to fund people in the first place

This is a disaster if the EU doesn't follow up by doubling the budget 😬🧪

Our paper on central complex evolution in Heliconiini butterflies is now available as reviewed preprint at @elife.bsky.social 🎉🎉. Please check out the helpful and constructive reviews which we are going to address in the next weeks 🤗 elifesciences.org/reviewed-pre... @ebablab.bsky.social

This is my impression too. The poorer our critical thinking skills, the less opposition there can be to fascist and autocratic power.

Please use alt text. For the obvious reason—that’s enough reason to do it, put on the setting that reminds you—but also because the words used in alt text work with filters.

What’s happening to the higher education sector in the States is absolutely shocking and should be a warning to all of us academics across the globe. A warning not to be scared and shut up but to stay alert and ready to uphold and defend our academic freedom.

I have made a discovery today that's GHGHHNNNNGNHNNNHN youtu.be/5VDU4UTDkhg?...