The regulatory landscape of optic fissure closure in the vertebrate eye https://www.biorxiv.org/content/10.64898/2026.02.11.705341v1

Enhancer-mediated metabolic pre-patterning defines trabecular cardiomyocyte identity prior to morphogenesis https://www.biorxiv.org/content/10.64898/2026.02.12.705356v1

A dual-phase enhancer couples progenitor maintenance and pancreatic lineage stability https://www.biorxiv.org/content/10.64898/2026.02.11.705016v1

Two axolotl-adapted cell-ablation platforms reveal macrophage-dependent processes essential for spinal-cord and skeletal regeneration https://www.biorxiv.org/content/10.64898/2026.02.10.705144v1

Embryonic and larval development of the Pacific saury Cololabis saira: Distinctive characteristics of a rapidly growing beloniform fish https://www.biorxiv.org/content/10.64898/2026.02.10.705229v1

High resolution spatial transcriptomic and proteomic profiling of early primate gastrulation in utero https://www.biorxiv.org/content/10.64898/2026.02.10.705168v1

Male fertility is independent of Enh13 control of Sox9 testicular expression https://www.biorxiv.org/content/10.64898/2026.02.09.704748v1

Kinetic Control of Out-Of-Equilibrium Dynamics in the RhoA Signaling Cascade Shapes Actomyosin Contractility https://www.biorxiv.org/content/10.64898/2026.02.08.704688v1

Pancreatic Duct Cells as a Potential Source for Human Islet Neogenesis: Insights from Imaging Mass Cytometry https://www.biorxiv.org/content/10.64898/2026.02.07.704527v1

Ancient origin of the dorso-ventral patterning system of vertebrate paired fins https://www.biorxiv.org/content/10.64898/2026.02.08.704681v1

Cajal-Retzius fate specification is disrupted by constitutive activation of β-Catenin in hem progenitors https://www.biorxiv.org/content/10.64898/2026.02.09.704731v1

Inflammatory IL-1 signaling remodels epidermal stem cell compartments by suppressing Wnt activity https://www.biorxiv.org/content/10.64898/2026.02.06.704488v1

Mechanistic tradeoffs between local and long-range signaling activity in natural and synthetic morphogens https://www.biorxiv.org/content/10.64898/2026.02.06.704427v1

Determinants of the Transition Zone Width of Morphogen Readouts https://www.biorxiv.org/content/10.64898/2026.02.06.704367v1

Segmented wavetrains and sites of reversal in the mouse seminiferous tubules https://www.biorxiv.org/content/10.64898/2026.02.06.703668v1

Hypoxia differentially affects coronary vessel formation during heart development https://www.biorxiv.org/content/10.64898/2026.02.06.704033v1

Electrical stimulation combined with p27Kip1 inactivation drives proliferative neurogenic reprogramming of Mueller glia in the adult mouse retina https://www.biorxiv.org/content/10.64898/2026.02.05.704102v1

A Functional Basis for the Developmental Sequence of the Macrostructure of the Venus Flower Basket (Euplectella aspergillum) https://www.biorxiv.org/content/10.64898/2026.02.05.704042v1

Epitope-based labeling for improved live-imaging of endogenous proteins in C. elegans https://www.biorxiv.org/content/10.64898/2026.02.05.703904v1

Single-cell multiomic approaches define a gradual, spatially-regulated epigenetic and transcriptional transition from embryonic to adult neural stem cells https://www.biorxiv.org/content/10.64898/2026.02.06.704429v1

A knock-in Six2Cre line reveals transient interstitial potential in nephron progenitors https://www.biorxiv.org/content/10.64898/2026.02.04.703893v1

Directed conversion of porcine extended pluripotent stem cells into trophoblast-like stem cells through modulation of conserved TGF-β and ERK signaling pathways https://www.biorxiv.org/content/10.64898/2026.02.04.703856v1

Mutant FGFR3 restricts bone yet expands cortex via ERK-mediated self-repression https://www.biorxiv.org/content/10.64898/2026.02.03.703675v1

A transcriptional code controlling fluid shear stress-induced gene expression https://www.biorxiv.org/content/10.64898/2026.02.04.703710v1

Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 iPSC-derived neural cells https://www.biorxiv.org/content/10.64898/2026.02.05.704014v1

The Nkx2.3-Nr5a1 gene cascade plays a crucial role in spleen-specific vascular architecture and marginal zone formation https://www.biorxiv.org/content/10.64898/2026.02.02.703419v1

A Multi-tissue Transcriptomic-Metabolomic Map Linking Maternal High-Fiber Diet to Reduced Offspring Type 2 Diabetes https://www.biorxiv.org/content/10.64898/2026.02.02.703389v1

Cell-intrinsic compliance mechanism enables release of tensile stress to prevent tissue rupture https://www.biorxiv.org/content/10.64898/2026.02.02.703250v1

PRDM16 is necessary for sensory neuronal development in the Trigeminal Ganglion https://www.biorxiv.org/content/10.64898/2026.02.01.702826v1

Cellular diversity of the developing chick trigeminal ganglion at single-cell resolution https://www.biorxiv.org/content/10.64898/2026.02.01.702869v1

Synthetic germ granules reveal a direct role of Vasa/DDX4 in RNA localization and translational activation https://www.biorxiv.org/content/10.64898/2026.02.01.703065v1

Maternal-fetal immune conflict contributes to male-specific impairments in a mouse model of neurodevelopmental disorders https://www.biorxiv.org/content/10.64898/2026.02.02.703351v1

Arginine Kinase 1 regulates energy homeostasis in Drosophila muscle development https://www.biorxiv.org/content/10.64898/2026.01.30.702107v1

A stress-responsive morphogenetic program of the uterine epithelium safeguards the establishment of early pregnancy https://www.biorxiv.org/content/10.64898/2026.01.29.702684v1

Single-cell multiomics identifies key nodes and cis-regulatory elements of the networks specifying the eye domains in zebrafish https://www.biorxiv.org/content/10.64898/2026.01.31.703039v1

Neonatal diethylstilbestrol exposure disrupts uterine epithelial apical-basal polarity and partial EMT state https://www.biorxiv.org/content/10.64898/2026.01.29.702663v1

Tenascin N contributes to spinal motor nerve morphogenesis during development https://www.biorxiv.org/content/10.64898/2026.01.29.702601v1

Light-entrained chromatin priming poises rapid metamorphosis in a marine sponge https://www.biorxiv.org/content/10.64898/2026.01.28.702437v1

Prenatal corticosteroid exposure disrupts vascular-immune interactions and impairs steroidogenesis in the fetal testis https://www.biorxiv.org/content/10.64898/2026.01.27.702066v1

Notch signaling in the embryonic ectoderm promotes periderm cell fate and represses mineralization of vibrissa hair follicles https://www.biorxiv.org/content/10.64898/2026.01.27.702034v1

Establishing genetically controlled, closed 1 colonies of an ascidian https://www.biorxiv.org/content/10.64898/2026.01.29.702678v1

MYRF drives heterochronic miRNAs and LIN-42, and amplifies oscillatory programs for stage transitions https://www.biorxiv.org/content/10.64898/2026.01.27.701908v1

Profibrotic Changes Following Tension Application in a Fetal Lamb Model of Long Gap Esophageal Atresia https://www.biorxiv.org/content/10.64898/2026.01.26.701811v1

Hyaluronan underlies the emergence of form, fate, and function in human cardioids https://www.biorxiv.org/content/10.64898/2026.01.26.700345v1

Ybx1 Deficiency Causes ROS-Driven IBD-Like Intestinal Inflammation and Postnatal Lethality https://www.biorxiv.org/content/10.64898/2026.01.26.701719v1

Mechanically competitive regulation of cell volume in cytoplasm-sharing cells connected by intercellular bridges https://www.biorxiv.org/content/10.64898/2026.01.26.701669v1

Functional Redundancy of ZmSWEET6a/b in Mediating Sugar Transport and Redox Homeostasis for Maize Primexine Formation https://www.biorxiv.org/content/10.64898/2026.01.25.701620v1

Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure https://www.biorxiv.org/content/10.64898/2026.01.26.701676v1

A role for HDAC3 in regulating histone lactylation and maintaining oocyte chromatin architecture and fertility https://www.biorxiv.org/content/10.64898/2026.01.26.701805v1

Clocks and Dominoes: Timing Mechanisms of Embryogenesis https://www.biorxiv.org/content/10.64898/2026.01.25.701537v1