NFYA regulates two sequential genome-wide transcriptional activation events during oocyte-to-embryo transition https://www.biorxiv.org/content/10.64898/2026.03.30.715371v1

Integrated quantitative imaging and biomechanical modeling of early gastrulation in C. elegans https://www.biorxiv.org/content/10.64898/2026.03.30.715391v1

Dissecting developmental origins and pericyte dynamics during coverage of brain vessels https://www.biorxiv.org/content/10.64898/2026.03.30.715397v1

Nematic structures contribute to robust zygotic polarization in C. elegans https://www.biorxiv.org/content/10.64898/2026.03.30.715403v1

An integrated single cell and spatial omics atlas of human prenatal development https://www.biorxiv.org/content/10.64898/2026.03.30.714220v1

Deletion of the Wnt regulator Znrf3 alters bone geometry without inducing high bone mass https://www.biorxiv.org/content/10.64898/2026.03.30.715366v1

Hierarchical Assembly of Native Cytoplasmic Lattices Revealed by Cryo-EM https://www.biorxiv.org/content/10.64898/2026.03.30.715201v1

Smad6-mediated inhibition of BMP/TGF-β signaling disrupts midbrain growth in chick embryos https://www.biorxiv.org/content/10.64898/2026.03.30.714515v1

Proliferation and differentiation in intestinal organoids as a balance of ligand-modulated the EGFR trafficking https://www.biorxiv.org/content/10.64898/2026.03.30.715070v1

Synthetic lumen rounding directs neural progenitor division mode https://www.biorxiv.org/content/10.64898/2026.03.30.715222v1

Positional cues, not Notch, direct Neuroblast selection during early neurogenesis in the Drosophila embryo https://www.biorxiv.org/content/10.64898/2026.03.30.715196v1

Psi represses EGFR signalling in the neural stem cell niche to inhibit neuroblast proliferation in the Drosophila brain https://www.biorxiv.org/content/10.64898/2026.04.01.715755v1

Evolutionary rewiring of the endomesoderm gene regulatory networks specify skeleton secreting cells in stony corals. https://www.biorxiv.org/content/10.64898/2026.03.31.715602v1

Disease-associated microRNA, miR-9-2, regulates timing of retinal progenitor cell competence and maintenance of Müller glial identity https://www.biorxiv.org/content/10.64898/2026.03.27.714903v1

EFN-4/Ephrin converges with SAX-3/Robo, UNC-6/Netrin, and Heparan Sulfate Proteoglycan signaling to control MAB-5/Hox-dependent posterior Q neuroblast migration in Caenorhabditis elegans https://www.biorxiv.org/content/10.64898/2026.03.27.714887v1

Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen https://www.biorxiv.org/content/10.64898/2026.03.27.714580v1

Defining early human developmental identity: A curated, cross-platform marker framework https://www.biorxiv.org/content/10.64898/2026.03.26.714482v1

Expanding the C. elegans toolkit with gonad explants https://www.biorxiv.org/content/10.64898/2026.03.26.714430v1

Canonical mTOR signaling supports complete fin regeneration https://www.biorxiv.org/content/10.64898/2026.03.27.714790v1

Stage-resolved iPSC-to-motoneuron differentiation: Metabolic switch & mitochondrial remodeling https://www.biorxiv.org/content/10.64898/2026.03.25.714145v1

Abnormal ventricular wall patterning precedes and drives MYBPC3 hypertrophic cardiomyopathy https://www.biorxiv.org/content/10.64898/2026.03.25.714341v1

Increases in BCL2L1 and ID1 dosage synergistically drive fate bias and competitive advantage in human pluripotent stem cells https://www.biorxiv.org/content/10.64898/2026.03.26.714405v1

Notch mediated lateral inhibition is shaped by morphological differences to reinforce bias toward signal-sending or receiving roles https://www.biorxiv.org/content/10.64898/2026.03.27.712410v1

A Reproducible Fetal Lamb Model of Complex Gastroschisis with Temporal Characterization of Bowel Changes https://www.biorxiv.org/content/10.64898/2026.03.25.714287v1

Validated CRISPR/Cas9 guide RNAs targeting neurodevelopmental genes in the tunicate Ciona robusta https://www.biorxiv.org/content/10.64898/2026.03.25.711585v1

A Wnt-responsive fibrocartilage progenitor system coordinates postnatal mandibular condylar cartilage growth https://www.biorxiv.org/content/10.64898/2026.03.25.714159v1

Mitochondria-Associated Transcription Precedes Oxidative Phosphorylation Activation During Human Pre-Implantation Embryogenesis https://www.biorxiv.org/content/10.64898/2026.03.25.714226v1

Mitochondrial subpopulations in oocytes and cumulus cells exhibit distinct age-associated changes and selective plasticity in response to NMN supplementation https://www.biorxiv.org/content/10.64898/2026.03.25.714214v1

Mining functional genes and characterizing cellular transcriptomic profiles in the single-cell atlas of adult Spodoptera litura ovary https://www.biorxiv.org/content/10.64898/2026.03.25.713648v1

Embryo-eggshell interaction counteracts chiral bias in early Drosophila morphogenesis https://www.biorxiv.org/content/10.64898/2026.03.25.714261v1

Cascading periods of language-related brain plasticity across early childhood https://www.biorxiv.org/content/10.64898/2026.03.27.714739v1

Regulation of PDGF-BB Signaling in Placental Pericytes by Soluble PDGFRβ Isoforms: Implications for Fetoplacental Vascular Development https://www.biorxiv.org/content/10.64898/2026.03.24.713995v1

Rapid in vitro platform for functional analysis of maternal effect genes during mouse oocyte growth https://www.biorxiv.org/content/10.64898/2026.03.24.709698v1

EpiCure (Epithelial Curation): a versatile and handy tool for curation of epithelial segmentation https://www.biorxiv.org/content/10.64898/2026.03.27.714683v1

A mitochondrial program encodes brain vascular reserve https://www.biorxiv.org/content/10.64898/2026.03.25.714175v1

Uncovering zebrafish embryonic proteome dynamics across 16 time points during the first 24 hours of development https://www.biorxiv.org/content/10.64898/2026.03.24.713983v1

Aging compromises Zebrafish caudal fin regeneration by disrupting Regenerative gene networks and Cellular metabolism https://www.biorxiv.org/content/10.64898/2026.03.24.713633v1

Heparan sulfate is essential for Drosophila FGF export https://www.biorxiv.org/content/10.64898/2026.03.24.714045v1

MLL3/4 methyltransferases regulate the differentiation of pluripotent stem cells via cellular respiration https://www.biorxiv.org/content/10.64898/2026.03.24.713976v1

Distinct signaling center and progenitor identity dynamics initiate human forebrain patterning https://www.biorxiv.org/content/10.64898/2026.03.25.714146v1

Developmental determinants of male bias in medulloblastoma https://www.biorxiv.org/content/10.64898/2026.03.25.714163v1

Natural variation in transplacental transfer efficiency exposes distinct transcriptional network architectures of PFAS effects on birth weight and gestational age https://www.biorxiv.org/content/10.64898/2026.03.23.712893v1

Chronic morphine treatment induces a conserved Smchd1-dependent epigenetic memory that disrupts X-chromosome inactivation and genomic imprinting https://www.biorxiv.org/content/10.64898/2026.03.23.713629v1

The glp-1 3' untranslated region regulates germline proliferation and promotes reproductive fecundity through multiple mechanisms https://www.biorxiv.org/content/10.64898/2026.03.23.713686v1

Mitochondrial metabolic remodeling drives innate immune activation in Drosophila hemocytes https://www.biorxiv.org/content/10.64898/2026.03.23.713618v1

Tau regulates epithelial morphogenesis through vesicle trafficking dependent Notch activation https://www.biorxiv.org/content/10.64898/2026.03.23.713835v1

A postnatal human lung developmental atlas reveals windows of genetic vulnerability to chronic lung disease https://www.biorxiv.org/content/10.64898/2026.03.20.713166v1

Developmental regulation of progenitor aging shapes long-term intestinal homeostasis in Drosophila https://www.biorxiv.org/content/10.64898/2026.03.21.713357v1

KELPE: knock-in exchangeable dual landing pad embryonic stem cells enable efficient screening of synthetic gene circuits https://www.biorxiv.org/content/10.64898/2026.03.22.713470v1

ZMAP: A single-cell meta-atlas of zebrafish embryonic development reveals a consensus hierarchy of cell identities https://www.biorxiv.org/content/10.64898/2026.03.23.713599v1