Letter of resignation from @jennifer-troyer.bsky.social former Dir of Extramural Ops at NHGRI "The NIH is not only no longer the organization that I love but is now an organization that I can no longer be a part of and retain my integrity and self-respect." www.linkedin.com/posts/jennif... 1/6

I’m running for Congress in NY-12, my home. We have a demented, criminal president running the country like a mob operation—government by the boss, for the boss. We need Democratic fighters who will defend the rule of law and deliver government by the people. Join us.

The district court injunction that prevented NIH from capping indirects at 15% was upheld today on appeal! www.reuters.com/world/trump-...

Tfw you're a PI and winter staycation lets you test crazy ideas and submit a bunch of supercompute model optimization jobs that you never have time to do during the semester and get a really fucking cool result. Either a bug or a paper lol

A history of how the #NIH came to be. The purpose of the NIH is to support science innovation. Government support of science grows the economy, brings power and prosperity to the country. This was part of the budget increase after WWI. It became our backbone. 🧪 theconversation.com/how-the-nih-...

Science 🤝 Democracy. The Trump admin's fight against science harms our 1st Amendment rights. Flipping a complicit Congress is critical in the fight against unpatriotic anti-science, and where the Science Fight Club comes in. Find out how to join the fight here: zurl.co/fa315 #standupforscience

To life, liberty, and pursuit another go around, friends

On delayed application review, the NIH grant terminations lawsuit appears to be headed for a settlement. Both plaintiffs and defendants have submitted a joint document outlining their agreement. Judge Young must sign off on it before it takes effect. Here's what it says and what all this means 🧵

ACLU: NIH Agrees to Evaluate and Complete Review on Stalled Scientific Grant Applications Parties resolve claims on behalf of applicants harmed by unlawful directives bit.ly/4jg5SSW @aclu.org @apha.org @aclum.bsky.social

Every single time Trump has a meeting with Zelensky, Putin calls Trump the day before and Trump’s position in the Zelensky meeting then mirrors the Russian position. The talking points are the same, with all the same lies. It’s a simple playbook for Putin and it works every time.

Statement from the American Academy of Neurology: “This decision was made without consulting key neurology stakeholders, and there was no formal announcement nor a clear succession plan for NINDS leadership. NINDS plays a vital role in funding and directing research into the brain”

Bichan Wu (@bichanw.bsky.social) & I wrote a tutorial paper on Reduced Rank Regression (RRR) — the statistical method underlying "communication subspaces" from Semedo et al 2019 — aimed at neuroscientists. arxiv.org/abs/2512.12467

A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research, writes @alexkwan.bsky.social. www.thetransmitter.org/drug-develop... #neuroskyence

An awesome figure illustrating key aspects of hippocampal encoding and replay during continuous behavior ; from great work by Brian Lustig and co www.biorxiv.org/content/10.6...

I thought it was Kpop Demon Hunters

Sorry hiber-what now?!

NSF - Forced reorg - POs down ~ 40% (DRP, most rotators not renewed, retirements) - Forced move (and we have to pack and clean) to a building with no furniture, little to no conference space for panels, inadequate 🛜, …) I personally love the boxes they gave us for packing. “Details matter” 🙃

With Masashi launching his new lab, we’ll be recruiting a new postdoc in the Oldenburg Lab. Work: high-precision multiphoton holography, neural coding, motor cortex circuits, all-optical physiology. If you’re interested, just reach out.

Thrilled to be a part of this AFOSR-funded project bridging across scales to probe energy efficiency of neural circuit function, and understand how the brain adapts and prioritizes competing cognitive demands under resource constraints, with implications for neuromorphic computing! bit.ly/44h9oq5

It's almost as if the Coast Guard is better at the job of apprehending drugs without killing anyone.

Under Trump, the NIH is giving fewer grants to fewer scientists. The grants awarded are smaller and scientists have less time to spend them. Projects in cancer, diabetes, aging, neurological disorder, and more are going unfunded. “Make America Healthy Again.”

There's new guidance with respect to #foreignawards at #NIH. Please share with your networks. #foreignsubs #funding

This field is on fire. So many cool methods these days. Happy Thanksgiving friends!

How prior experience biases new learning for generalization? new preprint is out: 1) behavioral and hippocampal generalization co-emerged in a novel context. 2) BTSP was involved in forming cross-context stable representations, as well as aligning novel neural dynamics to familiar subspace.

Andrea is one of over 170 U.S. citizens who have detained by ICE. It should never have happened, and we will hold Kristi Noem and the Trump Administration accountable.

🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇 kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification https://www.biorxiv.org/content/10.1101/2025.11.20.689599v1

Sorry, WTAF?

Simulation-based inference has really become a commonly used tool for parameter inference across many fields and applications. We (finally...) got together to write a tutorial introduction and guide to (hopefully) help users get started and navigate the different methods and diagnostics!

Every member of Congress and frankly every American should denounce what Trump did today in suggesting members of Congress be executed. It shouldn't even need to be said, but apparently does: it is beyond the pale for anyone to suggest such things, let alone the president of the united states.

Who are civil servants and mission-oriented. It is a Bad Thing to put NIH under control of political appointees and the president. It is breaking what made NIH great.

BTSP in V1 www.biorxiv.org/content/10.1...

BTSP in V2

High school students? How about Cabinet appointees

We also have a review out in JNeuro on the topic with @neurosutras.bsky.social, Tom O'Dell, Anant Jain, @clopathlab.bsky.social and Mark Sheffield. Physical copies available at @sfnjournals.bsky.social booth. www.jneurosci.org/content/45/4...

A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions. A bit of a video explainer here: 1/ 🧪

Trump’s HHS put me on “non-disciplinary” admin leave today. This was retaliation for speaking up. Moves like this are designed to silence us. Let’s not let. www.tiktok.com/t/ZP8Dteoop/

The loss of SNAP, the doubling of premiums, the cancelled flights, the furloughed workers were all the result of GOP House being intentionally out of session. The Senate Democrats got cold feet because we all need to fly home and buy turkeys for Thanksgiving. Everyone lost.

bluesky branding refresh unveiled

My kids have measles and my SNAP benefits were cut. But at least those cashiers at Walmart aren’t writing “they/them” on their name tags anymore.

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

Submitted a paper revision today. Project started in 2021. Received positive constructive addressable reviews this August. This paper is the best of my career. Working with postdoc @argalloni.bsky.social has been the most rewarding scientific relationship of my career.

Join us for a BTSP mini symposium Tuesday morning of SfN: Behavioral Timescale Synaptic Plasticity: Phenomenology, Mechanisms and Role in Learning and Memory www.abstractsonline.com/pp8/#!/21171...

Want to see what a Neuromatch course is like…on your own time? Our full course materials are freely available for anyone to explore, anytime. While the live courses include team projects, TAs, and learning pods, the content itself is always open. ➡️ neuromatch.io/open-educati...

Here's the link to the system, try it! qedscience.com @qedscience.bsky.social

Connectome suggests brain’s synaptic weights follow heavy-tailed distributions, yet most analyses of RNNs assume Gaussian connectivity.  🧵⬇️ Our @alleninstitute.org #NeurIPS2025 paper shows heavy-tailed weights can strongly affect dynamics, trade off robustness + attractor dimension.