We are excited to announce up to 3 PhD positions in a new project on using ML for "Extracting Probabilistic Representations in Exponential Quantum Spaces" (EXPRESSO) with @philipphennig.bsky.social , @mariokrenn.bsky.social, Igor Lesanovsky, @gmartius.bsky.social in the @ml4science.bsky.social.

Our paper "Neural timescales from a computational perspective" is finally out in @natneuro.nature.com: www.nature.com/articles/s41... We discuss how computational models and methods can distill empirical observations on neural timescales into quantitative, testable theories of brain computation.

ModelSMC: we frame LLM-based scientific model discovery as Bayesian inference. Sequential Monte Carlo over executable model structures, with the LLM as a probabilistic proposal mechanism. 📍 Wed Jul 8, at 2:30–4:15 PM KST in Hall A #3512 📄 arxiv.org/abs/2602.18266 🧵 bsky.app/profile/mack...

Happy to have joined the ELLIS Institute! Excited to be working with the PIs at the Institute and the ELLIS network more broadly!

We congratulate @matthijspals.bsky.social on his successful PhD defense! During his time in the Mackelab, he used RNNs to link neural activity with underlying mechanisms. Now he moved on to a Postdoc position in @durstewitzlab.bsky.social at the ZI Mannheim and the University of Heidelberg.

New paper: We recast automated scientific model discovery with LLMs as Bayesian inference! LLMs write code and carry domain knowledge, great for proposing models. The key idea: discovery is inference, not just generation. What distribution of models explains the data? 🧵 arxiv.org/abs/2602.18266

We are recruiting several Early Career Research Group Leaders for Machine Learning in Science (m/f/d; E14 TV-L, 100%) in Tübingen! Open to researchers directly after their PhD or with postdoctoral experience. Application deadline: July 15, 2026. More info: uni-tuebingen.de/en/128980#c2... 1/2

Great opportunity: The Leibniz Institute for Neurobiology @linmd.bsky.social + University @uni-magdeburg.de Magdeburg are hiring a Full Professor/Research Group Head in Integrative Neurobiology, especially computation, theory neurotech! Apply by 29 May 2026 ncloud.lin-magdeburg.de/s/cnSj2Ys5YE...

For its 50th birthday*, MLSS is back in Tübingen— come to beautiful Tübingen to learn about ML from great speakers, and, most importantly, meet lots of other students and researchers!!!

We're excited to welcome our 2026 AIMS Fellows: Ndim Handson Nsani, Arlette Musanabera, Vongai Mitchell Makuwaza, Dzodzoenyenye Senanou and Benedict Ositadinma Ejelonu have recently arrived in Tübingen and started their nine-month research visit. We wish them a productive and rewarding stay!

sbi v.0.26.1 is out 🎉. We initially planned this release for January, but then the Grenoble Hackathon and GSoC applications happened. Now we have three new methods, better neural nets, cleaner internals, better docs, and 9 new contributors 🤗. Highlights below 🧵

We’re launching a new AI Methods & Software Hub in the ML cluster and are looking for a Director to build and lead it! Shape how ML/AI and software drive scientific discovery—in close collaboration with AI and domain scientists—within an extremely vibrant and collaborative ecosystem!

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...

How academic are different cities in Germany? The one definite ranking. #exinit @unituebingen.bsky.social

🚨 We're hiring: Research Coordinator for CRC Robust Vision @unituebingen.bsky.social Take a leading role in our DFG funded consortium in neuroscience, ML & CV MSc/PhD + science mgmt. Apply by Mar 15 👇 join our team w/ @jakhmack.bsky.social @bethgelab.bsky.social uni-tuebingen.de/en/universit...

Hiring now! 📢 The CRC 1233 Robust Vision consortium at @unituebingen.bsky.social is looking for a Research Coordinator to lead science management, support project execution, and help steer our interdisciplinary research in neuroscience, machine learning and computer vision.

A special year for the Cajal Course in Computational Neuroscience: the BRAIN Prize winners Haim Sompolinsky and Larry Abbott will join us as keynote speakers. And we will bring you the same great roster of instructors as every year. Applications are now open! cajal-training.org/on-site/comp...

SBI Hackathon Grenoble is a wrap! 🎉 35 researchers and a great hybrid format of 1.5 days of tutorials + 1.5 days of applied hackathon. Many went from “having heard of sbi” to applying full SBI workflows to their own research projects. 🧵👇

Happy 2026 everyone! Two freshly minted PhDs 🧑‍🎓emerged from our lab at the end of last year. We congratulate Dr Julius Vetter (@vetterj.bsky.social) and Dr Guy Moss (@gmoss13.bsky.social)! Here seen celebrating with the lab 🎳. 1/3

📢We’re hiring: W3-Professorship in Machine Learning in Physics @unituebingen.bsky.social! What we’re looking for: Established research profile in a core area of #physics (condensedmatter, quantum or theoretical particle physics), strong track record in research questions related to #ML and/or #AI.

Congrats to all the ERC COG recipients, of course especially to the 5 from @unituebingen.bsky.social, and even more so to the @ml4science.bsky.social members @tobiasuhauser.bsky.social and @andreasgeiger.bsky.social (AI assistants!)!!! erc.europa.eu/system/files...

Come work with us!!!

Finally got the job ad—looking for 2 PhD students to start spring next year: www.gao-unit.com/join-us/ If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply! I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

We were asked to do an online training on 'AI awareness' by admin. I almost failed the test, as I was not aware of some of the fundamental limitations of #AI4Science.

Not going to NeurIPS Nor Eurips, but the lab is showing cool new work on SBI and differentiable biophysics, do check it out and talk to them (we also have open positions …)!

@gmoss13.bsky.social et al sending SBI to space 🚀*!!!

On our blog: For decades, brain simulations have either been largely simplified, or they could not perform cognitive tasks. #JAXLEY, a new AI tool, opens possibilities to build brain simulations that overcome both limitations: www.machinelearningforscience.de/en/jaxley-ai... #AIforScience

Possibly the best part of the job: The amazing students and scientists we get to work with!

Simulation-based inference has really become a commonly used tool for parameter inference across many fields and applications. We (finally...) got together to write a tutorial introduction and guide to (hopefully) help users get started and navigate the different methods and diagnostics!

I am super happy to share that our project on training biophysical models with Jaxley is now published in Nature Methods: www.nature.com/articles/s41...

Great new work from the labs of @jakhmack.bsky.social and @philipp.hertie.ai! The software Jaxley enables brain simulations which both imitate the processes in the brain in detail and can solve challenging cognitive tasks. Press release of @unituebingen.bsky.social: uni-tuebingen.de/en/universit...

Congrats to @deismic.bsky.social and everyone for getting this out!

“Mapping ion channel function” doi.org/10.7554/eLif... isn’t exactly a citation slayer, but it’s still one of my favourites (& my first independent project). Today we push pt 2, where we trace code origin & unite almost all channel models in a common expression. Boom! www.biorxiv.org/content/10.1...

🎉 sbi participated in GSoC 2025 through @numfocus.bsky.social and it was a great success: our two students contributed major new features and substantial internal improvements: 🧵 👇

Hello Frankfurt 🇩🇪 - We are excited to share the latest result from our group and collaborators at @bernsteinneuro.bsky.social 🚀🧠 #BernsteinConference Thanks to @brainloops.bsky.social, @ekfstiftung.bsky.social and @cherish-msca.bsky.social for supporting these projects and our scholars.

The Macke lab is well-represented at the @bernsteinneuro.bsky.social conference in Frankfurt this year! We have lots of exciting new work to present with 7 posters (details👇) 1/9

From hackathon to release: sbi v0.25 is here! 🎉 What happens when dozens of SBI researchers and practitioners collaborate for a week? New inference methods, new documentation, lots of new embedding networks, a bridge to pyro and a bridge between flow matching and score-based methods 🤯 1/7 🧵

Sharing this here a bit late, but @vstaros.bsky.social and I wrote a little something about our experience contributing to the @sbi-devs.bsky.social (simulation-based inference) hackathon. @mlcolab.org @mackelab.bsky.social We were obviously very hungry while writing.

My first paper on simulation-based inference (SBI) as part of @mackelab.bsky.social! Exciting work on adapting state-of-the-art foundation models for posterior estimation. Almost plug-and-play, and surprisingly effective. Paper/code in thread below 🧵

I have been genuinely amazed how well tabpfn works as a density estimator, and how helpful this is for SBI ... Great work by @vetterj.bsky.social, Manuel and @danielged.bsky.social!!

Together with #AIMS, the African Institute for Mathematical Sciences, we have an exciting position to fill: The AIMS - Tübingen Junior Research Chair in Machine Learning for Science! 1/2

Come work with us in Tübingen! Our new professor @mariokrenn.bsky.social is looking for PhDs and postdocs! The group builds #AI systems for discovering new concepts, experiments and ideas in #physics. Find out more: uni-tuebingen.de/en/128980#c2... #AIforScience

👨‍💻 Open PI position in our institute 👨‍💻 !! If you are an expert in Computational Neuroscience and want to start your lab in Bordeaux, contact us ! www.fens.org/careers/job-... @neuromagendie.bsky.social @neurobordeaux.bsky.social

Sbi can take you places … very proud about @gmoss13.bsky.social et als work, a wild and serendipitous collaboration made possible by @ml4science.bsky.social!

I always find the figures from the @mackelab.bsky.social really clear and pretty! For example in arxiv.org/abs/2404.09636.

We’ve successfully automated part of the (neuro)scientific process. Now I may be out of a job. After a lot of iterations, here’s our framework for automatic discovery, built to embrace degeneracy and the realities of underconstrained modeling.

magic, by magician @bconfavreux.bsky.social, using a magic SBI-wand conjured with Poornima Ramesh, under the auspices of the wise @tpvogels.bsky.social!

Last month, we organized #ODIN2025 @alleninstitute.org (along w Karel, Saskia @sejdevries.bsky.social , David & Satra) with the theme "Integrating Scales & Modalities". See the videos📣👇 Full playlist: youtube.com/playlist?lis... 🎥 Speaker: alleninstitute.org/odin-symposi... youtu.be/N1IMki0RnIc?...

📢 Amazing speaker in our Neurocolloquium on Wed. May 21 at 4.15pm CEST: Marion Silies @unimainz.bsky.social‬ will talk about "From heterogeneous wiring to degenerative function in motion-detection circuit", live in Tübingen & in Zoom. 🙌 Host: @jakhmack.bsky.social 👉 Sign up: tinyurl.com/32ku5jth