Thank you for having me on BrainInspired, Paul @braininspired.bsky.social! It was such an honor to be on my favorite show—a rare place where we can leisurely talk about manifolds, latent circuits, power laws, and other esoteric ideas, and still be taken seriously in knowing they are all real.

We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. The full study is now online at Cell. @cp-cell.bsky.social Paper 👉 www.cell.com/cell/fulltex... Thread for a synopsis 👉 bsky.app/profile/alex...

Are manifolds real? Are latent circuits real? Tatiana @engeltatiana.bsky.social uses one, infers the other, and says yes to both. Also, how timescales are different and the same across the entire brain... braininspired.co/podcast/226/

Finally got the job ad—looking for 2 PhD students to start spring next year: www.gao-unit.com/join-us/ If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply! I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

In our Learning Club @cmc-lab.bsky.social today (Dec 4, Thu, 2pm CET), @hritz.bsky.social will tell us about his recent paper (👇) [joint work w/ Jonathan Cohen lab]. Want to attend, send an empty email to virtual [email protected] to get the link!

1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs. 🔗 doi.org/10.1101/2025... Led by @atenagm.bsky.social @mshalvagal.bsky.social

Thrilled to share our new paper! With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste. Link @nature.com: www.nature.com/articles/s41...

Excited to announce our book “Neuroevolution: Harnessing Creativity in AI Agent Design” by Sebastian Risi, Yujin Tang, Risto Miikkulainen, and myself. We explore decades of work on evolving intelligent agents and shows how neuroevolution can drive creativity in deep learning, RL, LLMs and AI Agents!

Psst - neuromorphic folks. Did you know that you can solve the SHD dataset with 90% accuracy using only 22 kb of parameter memory by quantising weights and delays? Check out our preprint with @pengfei-sun.bsky.social and @danakarca.bsky.social, or read the TLDR below. 👇🤖🧠🧪 arxiv.org/abs/2510.27434

I am super happy to share that our project on training biophysical models with Jaxley is now published in Nature Methods: www.nature.com/articles/s41...

🧪Preprint! How foragers depart from optimal models can tell us a lot about how they compute their decisions. A strong but underexplored departure is that foragers widely vary when they leave identical patches. A 🧵 doi.org/10.1101/2025... With @emmavscholey.bsky.social @brainapps.bsky.social

I rarely come on here or any social media, but wanted to share our latest preprint of large-scale human single neuron recordings during an auditory working memory task: doi.org/10.1101/2025... I'm very grateful to our patients, my co-authors and the funders. And to anyone who reads it :-) 🧠📈🧵👇(1/5)

Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41... #blueprint 1/7

How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )

📣 Apply now for the 🌵CaCTüS 3-month fully funded internship in Germany in 2026! Work on ML, theor. neuroscience, computational psychiatry, behavioral experiments or data analysis at a top institution in Tübingen. For students facing barriers in higher education. 👉 cactus-internship.tuebingen.mpg.de

Very much looking forward to this exciting lineup! Also excited about presenting our work on how timescales of environmental dynamics affect foraging decisions (Wednesday), a work together w/ Tiffany Ona, @neuroprinciplist.bsky.social, Bruno Cruz, @xindipoo.bsky.social and Peter Dayan

Our work with @pawa-pawa.bsky.social is out in Nature Machine Intelligence! The choice of activation function affects the representations, dynamics, and circuit solutions that emerge in RNNs trained on cognitive tasks. Activation matters! www.nature.com/articles/s42...

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions, writes Xiao-Jing Wang. #neuroskyence www.thetransmitter.org/neural-dynam...

First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience Our latest in @natrevneuro.nature.com Link: rdcu.be/eMX3E @jeffcolgren.bsky.social @msarscentre.bsky.social

I saw David (Anderson) present this at a meeting. It's incredible - the idea that we can finally record the neural correlates of emotions like "hanger" in the brain. Congrats to this team!

This looks quite exciting!

Exciting new work from former team members Eric Romero, Cwyn Solvi, Fei Peng and colleagues makes the cover of Science: affective contagion in bumblebees! www.science.org/doi/10.1126/...

New #NeuroAI preprint on #ContinualLearning! Continual learning methods struggle in mostly unsupervised environments with sparse labels (e.g. parents telling their child the object is an 'apple'). We propose that in the cortex, predictive coding of high-level top-down modulations solves this! (1/6)

How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social) doi.org/10.1101/2025...

Excited to announce our new pre-print (www.biorxiv.org/cgi/content/...)! This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/

🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity! We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have: (1) more corticospinal neurons (CSNs) (2) better hand dexterity (3) more dexterous climbing, which is linked to CSN number🧵

The final paper of my PhD is now out as a preprint. This is a follow-up piece in series of two companion papers modelling awareness and suppression in a new variant of continuous flash suppression. arxiv.org/abs/2510.17154 🧵 1/3

The applications for the new round of CaCTüS Internship are now open! This is an extraordinary opportunity for students from underrepresented backgrounds to develop research skills necessary for advancing their careers! www.projects.tuebingen.mpg.de/application/

Our new paper would not have been possible without a brilliant team! Huge thanks to Katie Keller, @rorycoleman.bsky.social, @noelleeghbali.bsky.social, Sarah Zylka, @neuroluci.bsky.social 🪰🧪✨ Especially grateful for guidance and inspiration by my mentor Vanessa Ruta www.biorxiv.org/content/10.1...

Architectural immunity: #ants alter their nest networks to prevent epidemics | Science @Science.org

I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island. doi.org/10.1126/sci... With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others

Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...

“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances: doi.org/10.1126/scia...

🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging. 👇🧵 nature.com/articles/s41... #Neuroscience #Psychedelics #BrainImaging

Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8

Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

🚨Registration for Mechanistic Basis of Foraging 2025 closes October 20th 🚨 Speakers @mkflugge.bsky.social @aaronbornstein.bsky.social @benhayden.bsky.social @ellileadbeater.bsky.social @davidrobbe.bsky.social @dlbarack.bsky.social @becketebs.bsky.social uobevents.eventsair.com/the-mechanis...

A study led by Cina Aghamohammadi is now out in ‪@natcomms.nature.com‬! We developed a mathematical framework for partitioning spiking variability, which revealed that spiking irregularity is nearly invariant for each neuron and decreases along the cortical hierarchy. www.nature.com/articles/s41...

Can general artificial intelligence emerge by not following the evolution of complex brains? In this 2022 paper with @brigan.bsky.social we argued that embodiment, mind reading (mirror systems), mental time traveling... are necessary conditions www.mdpi.com/1099-4300/24... @anilseth.bsky.social

Are top-down feedback connections enough for robust vision? We found ConvRNN with top-down feedback exhibiting OOD robustness only when trained with dropout, revealing a dual mechanism for robust sensory coding with @marco-d.bsky.social, Karl Friston, Giovanni Pezzulo & @siegellab.bsky.social 🧵👇

Dear Student, It has been wonderful to see you grow from a lab novice into a thoughtful experimentalist. The results you have generated rob me of sleep because I am so excited thinking about the potential that lies in them. Science can be exhilarating! (1/4)

A little backstory on this one: sometime during the pandemic @hannah-haberkern.bsky.social and I were chatting in the servery at @hhmijanelia.bsky.social about how to encourage interactions between people working on foraging (+ neuroscience) across different species and perspectives... 1/n

Plus, there's now a related conference organized by some wonderful people @unibirmingham.bsky.social in the UK, including @brainapps.bsky.social, @markdhumphries.bsky.social, and others. (Registration for this conference is still open until the 20th October!) uobevents.eventsair.com/the-mechanis...

Pleased to have this review out in @cp-trendsneuro.bsky.social. In it we discuss various aspects of the intersection between foraging behaviors and neuroscience, and offer some future directions: www.sciencedirect.com/science/arti...

A glimpse at what #NeuroAI brain models might enable: a topographic vision model predicts stimulation patterns that steer complex object recognition behavior in primates. This could be a key 'software' component for visual prosthetic hardware 🧠🤖🧪

I've been arguing that #NeuroAI should model the brain in health *and* in disease -- very excited to share a first step from Melika Honarmand: inducing dyslexia in vision-language-models via targeted perturbations of visual-word-form units (analogous to human VWFA) 🧠🤖🧪 arxiv.org/abs/2509.24597

🚨 New preprint alert! 🧠🤖 We propose a theory of how learning curriculum affects generalization through neural population dimensionality. Learning curriculum is a determining factor of neural dimensionality - where you start from determines where you end up. 🧠📈 A 🧵: tinyurl.com/yr8tawj3

If you are @ #BernsteinConference we have 4 posters, thread👇 P II 25, Tue 18–19:30: abstracts.g-node.org/conference/B... P IV 5, Wed 14-15:30: abstracts.g-node.org/conference/B... P II 25, Tue 18-19:30: abstracts.g-node.org/conference/B... P I 11, Tue 16:30-18: abstracts.g-node.org/conference/B...

Don't miss our posters at #BernsteinConference 😍

📢🦋 Our paper ‘Global selection on insect antipredator coloration’ is out and featured on the cover of @science.org We ran a huge experiment to find out how ecological context favours camouflage and warning colouration as antipredator strategies. 1/6 www.science.org/doi/10.1126/...