billionaire: i have 3 brains. in my skull interviewer: incredible

Another super fun combo lab holiday party this year with @jocelynrichard.bsky.social!

Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...

Some #FluorescenceFriday content for you - check out these anterior cingulate cortex neurons that project to the superior colliculus. Image by @izzabellagreen.bsky.social 🧠

NMDA receptor ablation in medial prefrontal cortex disrupts value updating and reward history integration https://www.biorxiv.org/content/10.64898/2025.12.06.692679v1

Excited to share our new GLP-1 receptor agonist study! Chronic semaglutide potentiates motivation for small food rewards and associated cues, but reduces intake when food is freely available—surprising twist! #GLP-1, #behavior #neuroscience #pharmacology 1/ 🔗 www.biorxiv.org/cgi/content/...

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455 #Neuroscience #TeachingJobs #AcademicJobs #HigherEd

In other exciting news, @mattgeramita.bsky.social’s @natneuro.nature.com + Eric Yttri paper exploring the neural circuits underlying hesitation just dropped today! 🧠🎤 To summarize the findings, please see my musical abstract (with apologies to Peter Frampton 🎶) www.nature.com/articles/s41... 🧪

We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. The full study is now online at Cell. @cp-cell.bsky.social Paper 👉 www.cell.com/cell/fulltex... Thread for a synopsis 👉 bsky.app/profile/alex...

The Office of Science and Technology Policy (OSTP) is seeking input on Federal policy updates to accelerate the American scientific enterprise. This is your chance to give some feedback on how the past ~10 months have gone for science. www.federalregister.gov/documents/20... I plan to highlight:

The first one is not a test of replicability. It is a test of generalization. It is important to stop conflating these.

After slow-walking critical funding for lifesaving research, the Trump administration has sabotaged the NIH grantmaking process so that researchers get LESS money on average and LESS time to use it.   No one is asking to fund less cancer research, but that's what's happening.

22% fewer NIH grants

“It’s giving mechanistic insight into how estrogen modulates reinforcement learning—all the way down to the molecular mechanism,” says Ilana Witten. By @avaskham.bsky.social #neuroskyence www.thetransmitter.org/sex-hormones...

Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level. 👉 www.nature.com/articles/s41...

So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking

Here we go. Its ALL #NIHGrant applications. Dec 8 is the new deadline. And a one page prelim data update will be accepted for all May Council submissions. grants.nih.gov/grants/guide...

So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking

Translation: partisan appointees overseeing ICOs can circumvent the peer review process by overriding Impact Scores when determining program grant paylines. Result: ideological choice over merit, lobbying, and corruption.

No more paylines at the NIH grants.nih.gov/news-events/...

we have PrEP because of these monkey studies. animal welfare in medical research is extremely strictly limited and regulated to ensure ethical use. there is no replacement for these animal models in biomedical research.

As the Neuroscience 2025 meeting comes to a close, it's time for us to think about the future. Do you want to help us shape neuroscience research and future @sfn.org meetings? Consider nominating yourself or colleagues: www.sfn.org/about/volunt...

We’ve thought a lot about how 💊 drugs act on dendrites of neurons, but what about when it is a 🧬 mutation that affects dendrites? PhD student Hao Wu studied #Scn2a deficiency in mice. Just out at @pnas.org, her research led to two major findings. www.pnas.org/doi/10.1073/... 1/6

@accumbenshelley.bsky.social re-writing the textbook on neural circuit function

This Week in The Journal #JNeurosci | How Partial Occlusion Influences Visual Processing; Hippocampal Ripples during Rest May Promote Motor Learning vist.ly/4f8bg

Go Tricia!!! 🫡🫡❤️❤️

So stoked to have our image on the cover of this week's issue of Journal of Neuroscience!! @sfnjournals.bsky.social #JNeurosci #SfN25. Check out the final version of the paper here www.jneurosci.org/content/45/4...

Blown away by all the interest in our work and fun connections this week at #SfN25. So proud and grateful to work with such an amazing group of people.

Update on a significant development NIH grant terms. On 10/1, a change to grant making regs went into effect that gives NIH more power to terminate grants for policy reasons. But to use this power, new grant terms must include specific language. See @aniloza.bsky.social w/ the story from July. 1/

These 2 UC President’s Fellows just learned that our hiring incentive is not going to be defunded….for now! UCs, please hire us for faculty positions ASAP haha!!! (But seriously if you’re at #sfn25 , let’s chat 😌)

*tapping the sign*

Good morning everyone! Suitably following the #dopamine dinner, we have our #dopamine symposium at 9:30am in SDCC room 6B! ‘Beyond Value: Non-canonical roles for dopamine in aversion and reward’ Come join us! 🧠 🧪

I fell ill and so can't be there as planned but #SfN25 this morning has awesome posters from lab members @nicglewwe.bsky.social and @micaelaporod.bsky.social

This morning #SfN25 check out @micaelaporod.bsky.social’s poster KK17, part of dream team collab with @nicolagrissom.bsky.social

The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum. If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

Okay cool science seekers @ #SfN25! Time to head to V7-11 to check out our posters. We are all over the brain studying sensory guided affective states and decision making.

Folks the Sharpe Lab are in the house for @sfn.org! 🎉 Come check out our talks and posters. We’ve been doing some cool stuff down under 🇦🇺 on dopamine, reinforcement learning, and remapping of the fear circuit. 🧠 🧪

For those of you headed to #SfN25 If you study social behaviors be sure to check out our posters. We will be presenting how the brain represents prosocial decisions, how dopamine dynamics relate to social memory, whether respiration relates to social hierarchies, and more!

🧠 The Cai Lab will be at #SfN25! Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓

The lab is presenting at #SfN2025 Come check out the amazing science being conducted by postdoc Nina Baumgartner @nbaumgar.bsky.social and grad student Alexa Jo Tellez! I am also recruiting a postdoc so please spread the word. #neuroskyence

Our lab has 2 great posters this year at #SfN25 and a collaborative poster making a computational modeling of the PPN. Come see us on Wednesday afternoon!

#SfN2025 here we come! I am thrilled to be joined at the Society for Neuroscience meeting this year by Madelyn Moore, @kelseyperson.bsky.social, @valeriarobleto.bsky.social, and Crystal Lemchi. If you are in San Diego for the conference, please stop by to say hi! 👋 🧪🧠🟦

The Day Lab will be representing our work at the annual Society for Neuroscience conference (@sfn.org) in San Diego this week in two sessions - stop by to see updates on a lot of really cool science! #SfN2025 #Neuroscience

The Society for Neuroscience meeting starts tomorrow! I prepared some microscopy images for display at the convention center in San Diego. Let me know if you see one of my images around! 🤓 🔬 🧠 @sfn.org #SfN25 #FluorescenceFriday

Book launch day is here 🚀 How to Change a Memory, in physical and audio form: www.amazon.com/How-Change-M... and here's a preview of one of the book's central themes: memories change and, as a result, we change too🧠. www.statnews.com/2025/11/04/a...

So stoked for another year with the best crew in the Art of Neuroscience exhibit at #SfN25! Thank you @artologica.net for compiling all the artists in one digital space for all to peruse!

I was hoping we would get the pre-SFN issue for the final version of this paper but stay tuned for an upcoming issue and a fun surprise

Just got an email from my SRO for the study section that was missed in October. Good news is that they are trying to reschedule ASAP (Dec/Jan). The bad news is that CSR is mandating that only the the top third (not half) of applications will get discussed for the next 2 rounds.

This coming week at #SfN25 come visit us at the Minnesota Graduate Program in Neuroscience booth at the grad fair! For applicants this cycle, note that the deadline is soon - Nov 20th. Also everyone check out the presentations at the meeting by UMN folks - shorturl.at/jNRxQ

Northern lights the past two nights