Federal Troops Arrive in Portland and Immediately Form Bands

Here's a hawk on our fence trying to find an opening to grab a chicken. (This hawk is way smaller than any fat hen we have)

Premium newsletter: Based on my estimates and analysis, OpenAI needs one trillion dollars in the next four years to build 17GW of data centers and other commitments, with at least $500 billion needed for company operations. There is not enough capital to do this. www.wheresyoured.at/openai-onetr...

Even when he’s playing my squad I find it hard to root against Calais Campbell. Elder millennial solidarity.

The pattern is called "Light spattering of mud over rosy creme"

What in god's name is going on with these cardinal uniforms?

The nature relaxation playlist ain't working today so I'm gonna be a real peach over email.

Ok any #biking people out there? I get too many flats on my daily bike ride across Bham. Thinking about two options: 1) Schwalbe Marathon Plus Tires Or 2) Tannus Armour tire liners GO.

Science FTW!!!! This is amazing.

Patched it. Now for the ride home.

Excited to share this new work from the lab, in collaboration with @jtuscher.bsky.social & Rob Sorge! Here, we used single cell transcriptional profiling to define molecular adaptations induced by chronic pain and opioid experience, which often occur in conjunction. www.biorxiv.org/content/10.1...

My back tire has never found a piece of glass or a fastener on the street it did not like.

Happy one year anniversary to this banger tweet that got so ridiculously blown out of proportion that it got us 70k wishlists in like a day

Vaccines cause adults Tylenol causes pain relief Neurodiversity is good

You should ignore any information that directly comes from the top of US Health agencies.

Gourd luck all!

Okay we're there.

The New York Times piece today about US science is terrible and wrong—in many ways. I could write a whole article about this, but as one example: “To close observers, the original crisis began well before any of this…” No. I’m a close observer of science, and this is incorrect.

🎉 Congratulations to Needhi Bhalla, UC Santa Cruz (www.bhallalab.com ), named a 2025 #ASCB Fellow! This honor celebrates her outstanding contributions to cell biology, leadership, & service. Fellows will be recognized at #CellBio2025 in Philadelphia this December. #CellBiology

Watching Cam Ward is fun, but otherwise #Titans are hard to watch.

Now I'm getting conflicting reports about whether the Rapture will be on Tuesday, Wednesday or Thursday, and, look, I know that TECHNICALLY no man knows the hour of His coming and all, but if we could actually pin this down on the schedule it'll help me plan the rest of my week, thanks

Forever remember Curly Churk...or else.

Excited to highlight a new paper from my graduate student Sergio Bernal Garcia who, together withLuke Hammond, developed RESPAN, a new deep-learning pipeline automating the segmentation of neuronal morphology and dendritic spines from fluorescent microscopy images: www.cell.com/cell-reports...

Pretty clear illustration of "you may as well stand up for what you believe in, they're coming for you anyway."

Check out this cool preprint from the Krashes and Lutas labs on the signaling mechanisms of semaglutide GLP-1R agonism in the dorsal vagal complex: www.biorxiv.org/content/10.1...

This is true, but also the context here is the incentive structure of science. I WISH most of my time could be reading and writing. In actuality, I spend a ton of time on bullshit that provides legal protection for my university, fielding email homework, and putting out fires.

"Treating careful scholarship as somehow less important than the acquisition of data can adversely affect the reliability of the scientific record and consequently, the course of science," writes H. Holden Thorp in a new #ScienceEditorial. https://scim.ag/4mqrKet

So we get fired if we talk about Captain Kirk of the USS Enterprise now? Is that how this works now?

Morning snicky snacks.

Finally, we are one very very small step closer to doing stuff Tony Stark did in the 1st Iron Man movie 17 years ago.

As much as we are mostly working on our own lab's papers or grants; we, as a collective, contribute to a consensus truth on how the brain works. It's a huge responsibility to synthesize and generate a consensus view. That's what will inform public health policy.

A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions. Lots of updates from the preprint!

The annual UAB CNC retreat starts tomorrow in our beautiful new Heersink Institute for Biomedical Innovation Conference Center! Join us for trainee and faculty science as well as a keynote presentation from @ishmailsaboor.bsky.social! Link to program below. www.uab.edu/medicine/cnc...

NPR reports over 30 people have been fired, put on leave or faced calls to resign over social media posts criticizing Charlie Kirk or issues around his assassination. Seems odd those supporting his open debate style seemingly want to limit debate on him. https://loom.ly/m_0MjDM

I'm interested in people's current feelings about Flywheel. MRI folks? has it been worth it for you lately?

"I was the last remaining Black full-time opinion columnist at the Post, in one of the nation’s most diverse regions. Washington D.C. no longer has a paper that reflects the people it serves." If you haven't already canceled your WaPo subscript, let the rest of their articles die behind a paywall.

Mad respect to the home in Nashville I just passed that is completely decked out and ready for #Halloween It is September 15th.

It is here. McCarthyism 2.0. Wrongthink now gets you on a list that is openly trying to liaison with the government (which has already said it will be doing similar work in the weeks to come). The list referenced below now exceeds 100,000 people. People on the list are already getting death threats.

Can’t stop, got heron shit to do.

Not interested in any more Carley Chirk content or opinions.

We have updated our preprint "A green lifetime biosensor for calcium that remains bright over its full dynamic range" with some new data - including this photo showing the difference in color for the Turquoise and Green lifetime probe. www.biorxiv.org/content/10.1...

Titans QB Cam Ward looking forward to his Nissan Stadium debut, which he hopes is a win. "I am excited for it. I get to go out there in front of a packed stadium for the first time, for real, not a preseason game." READ bit.ly/4pg4m5N

Check out this cool preprint from the Krashes and Lutas labs on the signaling mechanisms of semaglutide GLP-1R agonism in the dorsal vagal complex: www.biorxiv.org/content/10.1...

Here the authors make inferences about macrophage GLP-1R signaling linked to senescence and efferocytosis using a GLP-1R antibody that is not validated for detection of the GLP-1R. www.sciencedirect.com/science/arti...

There are two competing narratives on this: science changed, or Republicans changed. You can figure out for yourself which one is more likely.

Titanup! Cam Ward debut in Denver! #Titans #Titanup

Incredibly proud of @kxhuang.bsky.social for persisting with such a challenging dataset from her PhD! We found some intriguing genetic targets in a corticostriatal circuit that may be involved in the development of #anorexia nervosa 🤔 onlinelibrary.wiley.com/doi/10.1002/...

Its supposed to get down to 59 on Sunday but not sure if its False Fall 3 or Pre-Fall. I am lost.

Job growth over the first eight months of the year: 2015: 1.76 million 2016: 1.58 million 2017: 1.51 million 2018: 1.75 million 2019: 1.36 million 2020: [pandemic] 2021: 4.69 million 2022: 3.5 million 2023: 1.84 million 2024: 1.14 million 2025: 598,000 #trumpeffect www.msnbc.com/rachel-maddo...