Sergi Roig Puiggros
@sroig.bsky.social
📤 172
📥 324
📝 21
Developmental Neurobiology Postdoc - University of Geneva
pinned post!
I'm very excited to finally see this one out in
@natneuro.nature.com
! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n
www.nature.com/articles/s41...
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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience
Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...
https://www.nature.com/articles/s41593-025-02142-7
17 days ago
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Relating to our recently published paper in
@natneuro.nature.com
! 🔥🚨 Find here a research briefing that we wrote w/
@djabaudon.bsky.social
trying to reach a broader neuroscience audience! Enjoy the reading!
www.nature.com/articles/s41...
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https://www.nature.com/articles/s41593-025-02191-y
13 days ago
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Maëlle Guyoton
17 days ago
Delighted to have contributed to this thorough and collaborative piece of work with amazing colleagues and friends! 🧠🚀
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I'm very excited to finally see this one out in
@natneuro.nature.com
! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n
www.nature.com/articles/s41...
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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience
Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...
https://www.nature.com/articles/s41593-025-02142-7
17 days ago
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Sergi Roig Puiggros
Cedric Boeckx
23 days ago
Great
@natneuro.nature.com
study by
@sroig.bsky.social
@djabaudon.bsky.social
@jbmanent.bsky.social
& colleagues, showing “equivalent circuits can emerge in different spatial configurations, allowing diverse brain architectures to converge on similar functional outcomes” 🧪🧠🧬
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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience
Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...
https://www.nature.com/articles/s41593-025-02142-7
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Sergi Roig Puiggros
JB Manent
23 days ago
Very happy to have contributed to this wonderful/tentacular work alongside so many amazing colleagues and friends! It opens up new ways of understanding grey matter heterotopia associated with altered cortical function and
#epilepsy
in humans. 🧠🧪🔥
www.nature.com/articles/s41...
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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience
Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...
https://www.nature.com/articles/s41593-025-02142-7
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Sergi Roig Puiggros
Denis Jabaudon
4 months ago
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood.
www.science.org/doi/10.1126/...
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Cell-extrinsic controls over neocortical neuron fate and diversity
Cell-extrinsic cues are key for neocortical cell identity and diversity.
https://www.science.org/doi/10.1126/sciadv.adw0218
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Very happy to have contributed to this great story 🧠🚀. It focuses on environment-dependent neuronal identity acquisition in the cortex! Big congrats to Natalia Baumann, Ilaria Morassut and Sabine Fièvre for pushing this w/
@djabaudon.bsky.social
. Congrats to all!
www.science.org/doi/10.1126/...
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Cell-extrinsic controls over neocortical neuron fate and diversity
Cell-extrinsic cues are key for neocortical cell identity and diversity.
https://www.science.org/doi/10.1126/sciadv.adw0218
4 months ago
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Marc A. Marti-Renom
5 months ago
Super lab looking for postdoc ... do not miss it! 👇🏼
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Darío Lupiáñez
6 months ago
How bats developed their wings? 🦇 Turns out they reutilize existing gene programs 🔧 Find out more in our paper
@natecoevo.nature.com
in collaboration with
@fany-real.bsky.social
and
@stemundi.bsky.social
labs
www.nature.com/articles/s41...
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Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution
Single-cell comparison of developing bat and mouse limbs reveals conservation of cell populations and gene expression patterns, and suggests repurposing of genes involved in proximal limb development ...
https://www.nature.com/articles/s41559-025-02780-x
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Sergi Roig Puiggros
Oscar Marín Lab
6 months ago
1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the
#cortex
. This is the story
@cellcellpress.bsky.social
www.cell.com/cell/fulltex...
⬇︎ thread
@devneuro.bsky.social
@kingsioppn.bsky.social
@wellcometrust.bsky.social
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A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α partners with ERRγ and Mef2c to ...
https://www.cell.com/cell/fulltext/S0092-8674(25)00731-7
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Sergi Roig Puiggros
Riccardo Bocchi
7 months ago
Thrilled to co-chair Symposium S08: Developmental Origins of Astrocyte Diversity tomorrow at
#GLIA2025
! Join us for cutting-edge insights into how astrocytes are born , diversify, and shape brain function. Wed, July 9 | 🕙 10:00–12:00 With
@loulierk.bsky.social
, Maryam Faiz &
@sloanlab.bsky.social
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Sergi Roig Puiggros
Riccardo Bocchi
7 months ago
✨ Astrocyte diversity starts at the source! 🧬 We uncover how dual radial glia lineages generate distinct astrocyte subtypes in the neocortex — revealed by MERFISH, scRNA-seq & clonal tracing. 📍#GLIA2025 | Poster T10-010A 🧠 w/
@alanzhoujf.bsky.social
in Marseille Come talk glia with us!
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Sergi Roig Puiggros
Christian Mayer
7 months ago
Now out in
@natneuro.nature.com
: Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice. Congrats to first authors
@annrosebright.bsky.social
, Yana Kotlyarenko,
@flo-neuhaus.bsky.social
, and thanks to all collaborators!
www.nature.com/articles/s41...
1/n
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Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience
Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...
https://www.nature.com/articles/s41593-025-01999-y
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Sergi Roig Puiggros
Eve Seuntjens
8 months ago
We're hiring! Our lab is looking for a postdoc to investigate the
#evodevo
of
#cephalopod
brains. Did you recently graduate, and do you want to join our EU
#WEAVE
project with the Simakov and
@simon-sprecher.bsky.social
labs? Find the application form👇Thanks for RT 🐙🦑
www.kuleuven.be/personeel/jo...
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Postdoctoral researcher in evolutionary developmental neurobiology
Come join our EU cephalopod consortium to discover how octopuses and other coleoids developed their large nervous system. Postdoc position available in the Seuntjens Lab in Leuven, Belgium.
https://www.kuleuven.be/personeel/jobsite/jobs/60479471
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Very grateful to have been able to present our work at the
@corticodevelopment.bsky.social
meeting in Naxos! Thanks putting together such a great line of speakers in this amazing location! 🧠☀️🍕
8 months ago
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Sergi Roig Puiggros
Denis Jabaudon
8 months ago
Still openings, check it out!
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Sergi Roig Puiggros
Esther Klingler
9 months ago
🎉 Excited to share that our paper on FCDII is out today! 🙌🏻 Huge thanks to
@sbaulac.bsky.social
and @sara baldassari for bringing me on board and introducing me to the complexity of somatic mutations. Hope our work helps advance understanding of the disease mechanisms.
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Sergi Roig Puiggros
Arnau Sebé-Pedrós
9 months ago
Check out our latest work on the evolution of animal genome regulation out today in
@nature.com
. Nicely summarized below by
@ianakim.bsky.social
.
www.nature.com/articles/s41...
This is a major output from our ERC-StG project Evocellmap
@erc.europa.eu
at
@crg.eu
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Guille López-Bendito
9 months ago
🚨 We're hiring! A Research Project Manager position is open in our lab at the Institute of Neuroscience (CSIC-UMH, Alicante)! Join us in exploring how spontaneous activity shapes sensory circuits 🧠✨
@glb-lab.bsky.social
#Neuroscience
#Jobs
#ResearchManager
📅 Deadline: May 25
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Sergi Roig Puiggros
Denis Jabaudon
9 months ago
Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below.
authors.elsevier.com/a/1k-udL7PXu...
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Sergi Roig Puiggros
Katherine Brown
10 months ago
Find out more about this exciting initiative from Biology Open in this editorial and the accompanying preprint
www.biorxiv.org/content/10.1...
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Sergi Roig Puiggros
James Briscoe
10 months ago
Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by
@biologyopen.bsky.social
More innovation from
@biologists.bsky.social
Details here:
www.biorxiv.org/content/10.1...
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Esther Klingler
11 months ago
📣 Postdoc opportunity ! Our lab is hiring a funded postdoc to explore the development of fear circuits using slice electrophysiology. If you have expertise in this area and are interested about cutting-edge neuroscience, reach out ! 🤗
klinglerlab.org
Please share with your network 🙏
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Sergi Roig Puiggros
Guille López-Bendito
11 months ago
Super proud of this massive work led by Mar Anibal from the lab. Early rescaling of barrel maps is possible and thanks to a transcriptional switch in thalamic neurons! Check it out!
@neuroalc.bsky.social
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Sergi Roig Puiggros
Riccardo Bocchi
11 months ago
🌌 The journey into astrocyte diversity doesn’t stop here! Stay tuned for new insights into how their molecular and functional diversity originates during brain development. 🚀 A new story is coming soon—check out our bioRxiv preprint here:
www.biorxiv.org/content/10.1...
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Dual lineage origins of neocortical astrocytes
Astrocytes represent one of the most abundant cell types in the central nervous system, and play an essential role in nearly all aspects of brain functions[1][1]. Recent studies have challenged the no...
https://www.biorxiv.org/content/10.1101/2023.09.12.557313v1
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Sergi Roig Puiggros
Riccardo Bocchi
11 months ago
🚀 Think all white matter (WM) astrocytes are the same? Think again! 🌟 Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. 🧠
www.nature.com/articles/s41...
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Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter - Nature Neuroscience
White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in cerebellar WM, suggestin...
https://www.nature.com/articles/s41593-025-01878-6
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Sergi Roig Puiggros
Nature Neuroscience
11 months ago
White matter (WM)
#astrocytes
differ significantly from grey matter (GM) astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity 🧪🧠
www.nature.com/articles/s41...
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Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter - Nature Neuroscience
White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in cerebellar WM, suggestin...
https://www.nature.com/articles/s41593-025-01878-6
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Sergi Roig Puiggros
Awais Javed
11 months ago
Delighted to have this out as a preprint! Thanks to all authors, especially
@estherkli.bsky.social
and
@djabaudon.bsky.social
for leading the work. If you are interested in how conserved genes played a part in evolving human brains, give it a read!
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Esther Klingler
11 months ago
✨ We tend to think of species-specific differences as resulting from the presence of species-specific genes. In our latest work with
@djabaudon.bsky.social
, we show that building brains is not only about which genes you use, but also about when and where you do.
www.biorxiv.org/content/10.1...
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Denis Jabaudon
12 months ago
🧠Job Opening!🧠 We are opening 2️⃣! positions – bioinformatics / molecular biology – in a project studying how temporal patterns set up connectivity in human brain tissue.
@institutimagine.bsky.social
. Full details below, contact me for details if interested. And please retweet (re-bluesky?)!
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Julien Ferent
12 months ago
📢A position of assistant professor (tenure) in developmental biology with a focus on IPSC/organoid technologies will soon be open to competition for a profile in neurodevelopment or development in my research team affiliated to Sorbonne University (good level in French and qualification required).
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Sergi Roig Puiggros
Teresa Rayon
about 1 year ago
Join us in Paris 6-9 May 2025 for the
#EvoDevoTempo
conference (2nd edition) with a fantastic line up of speakers confirmed!! Organized by
@mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social
and me. Please RT to spread the word
meetings.embo.org/event/25-dev...
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Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
https://meetings.embo.org/event/25-dev-timing
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Sergi Roig Puiggros
James Briscoe
about 1 year ago
Our latest: how to generate the notochord "Timely TGFβ signalling inhibition induces notochord" A thread:
www.nature.com/articles/s41...
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Timely TGFβ signalling inhibition induces notochord - Nature
Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.
https://www.nature.com/articles/s41586-024-08332-w
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It was such a great pleasure to attend and participate to the
#ChristmasMeeting_IN
today! Thanks for the warm welcome and for putting together such a stimulating meeting!
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about 1 year ago
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Sergi Roig Puiggros
Instituto de Neurociencias CSIC-UMH
about 1 year ago
And now Sergi Roig Puiggros from
@genevunige.bsky.social
shows his work on the location-independent emergence of neocortical circuits.
#ChristmasMeeting_IN
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Sergi Roig Puiggros
Fekrije
about 1 year ago
Excited to announce the publication of our team's work suggesting a new framework for understanding hashtag#synapse hashtag#development and diversity in the mammalian hashtag#brain in Nature Neuroscience
rdcu.be/d2100
🧵
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Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells
Nature Neuroscience - Brain function requires the formation of diverse and specific synapses. The authors show that the molecular code specifying excitatory connectivity on Purkinje cells evolves...
https://rdcu.be/d2100
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Sergi Roig Puiggros
Oliver Harschnitz
about 1 year ago
Thrilled & immensely honoured to receive the Italian Science Fund (FIS) Starting Grant. We will uncover the mechanisms underlying HSV-1 latency and reactivation in human, disease relevant, cells. Postdoc positions in virology and human stem cell biology
@humantechnopole.bsky.social
available soon!
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Sara Bizzotto
about 1 year ago
‼️Job alert ‼️(please share) The lab is slowly growing 😃 I'm looking for a postdoctoral fellow in computational biology👇 Please get in touch if interested in the position!!
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M. Veronica Pravata
about 1 year ago
My first paper as lead author as a postdoc is out on bioRxiv! We show how CSTB influences ganglionic eminence development via intrinsic and extrinsic mechanisms. Huge thanks to
@rossdg.bsky.social
, Silvia Cappello, and the team for their collaboration on this exciting work!
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Sergi Roig Puiggros
SEBD
about 1 year ago
Estamos aquí! We are now here! Follow us for all things related with developmental biology research and outreach, from Spain to the world!
#SEBD
#DevBio
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Sergi Roig Puiggros
Sara Bizzotto
about 1 year ago
📢 Thrilled to announce that I’m opening my lab at Institut Imagine in January 2025!! We study
#SomaticMosaicism
#Neurodevelopment
#CellLineages
#DevelopmentalDisorders
And I'm recruiting!! ERC-funded postdoc, PhD student and research assistant positions are available👇
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