Nikos Konstantinides
@nkonst4.bsky.social
📤 744
📥 957
📝 153
pinned post!
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
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about 1 month ago
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Now in its final form published in
@devbiol.bsky.social
www.sciencedirect.com/science/arti...
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3 days ago
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Everything is a matter of perspective, dear Emmanuel… The further to the right you sit, the further left everyone else seems.
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5 days ago
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reposted by
Nikos Konstantinides
Carolina Rezaval
6 days ago
Our new preprint is out! A state-dependent neural circuit resolves approach–avoidance conflicts
www.biorxiv.org/content/10.6...
Fantastic work led by Devika Bodas, with key contributions from Marine Balcou, and a great collaboration with Lisa Scheunemann Lab, fearuting Şevval Demirci.
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https://www.biorxiv.org/content/10.64898/2026.02.05.704045v1Fantastic
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reposted by
Nikos Konstantinides
Jaime de Juan-Sanz
9 days ago
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to
@amrapalianjali.bsky.social
for spectacular work, and to all lab members for invaluable contributions!
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reposted by
Nikos Konstantinides
Ishier Raote
14 days ago
Postdoc job alert at Institut Jacques Monod in Paris! Interested in fundamental membrane trafficking? We seek a postdoc to study collagen secretion as a model for core principles of how cells and their environment build each other.
emploi.cnrs.fr/Offres/CDD/U...
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Portail Emploi CNRS - Offre d'emploi - Poste de chercheur postdoctoral en trafic membranaire fondamental et sécrétion du collagène (H/F)
Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler
https://emploi.cnrs.fr/Offres/CDD/UMR7592-ISHRAO-006/Default.aspx
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If you've had an amazing mentor that has shaped your and other colleagues' careers, this is the time to acknowledge them! See below and consider nominating them!
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16 days ago
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reposted by
Nikos Konstantinides
Lionel Christiaen, PhD (he/him/his)
20 days ago
Re-upping this as the deadline for abstract submission if so close ❗️🧪🧬🔬 Come discuss your latest research with movers and shakers in the field, including luminaries and journal editors. A whole-encompassing learning experience and networking opportunity. Not to be missed!
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reposted by
Nikos Konstantinides
Nicolas Minc
24 days ago
Latest work from the lab by Aude Nommick et al., in which we propose a "size-scaling" model for microtubule force exertion that regulates centrosome centration vs decentration during embryo development!
@ijmonod.bsky.social
www.biorxiv.org/content/10.6...
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reposted by
Nikos Konstantinides
James Lightfoot
29 days ago
Why do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by
@gunizgozeeren.bsky.social
and
@leoboeger.bsky.social
across the
@jameslightfoot.bsky.social
and
@monikakscholz.bsky.social
labs.
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Predatory aggression evolved through adaptations to noradrenergic circuits - Nature
Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp...
https://www.nature.com/articles/s41586-025-10009-x
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reposted by
Nikos Konstantinides
Institut Jacques Monod
about 1 month ago
✍️ New preprint from the Konstantinides Lab (
@nkonst4.bsky.social
) 📃 Evolutionary dynamics of temporal transcription factor series in the insect optic lobe 🔗
www.biorxiv.org/content/10.6...
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If you’re a young PI (or senior postdoc) heading to FENS, this one’s for you! It’ll be a lot of fun—and honestly, I can’t think of a better moment in one’s career to have a strong peer network.
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about 1 month ago
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reposted by
Nikos Konstantinides
Mateusz Ambrożkiewicz
about 1 month ago
Calling all senior postdocs and you g PIs for this wonderful symposium in Barcelona! Register and let's connect!
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reposted by
Nikos Konstantinides
Matthew L. Kraushar
about 1 month ago
yo 🦋 NEURO SKY 📣 the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona!
@young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
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Young PI Symposium 2026
Visit the post for more.
https://youngpisymposium2026.com/
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reposted by
Nikos Konstantinides
about 1 month ago
Step into a Europe-wide community of neuroscience leaders. Junior & mid-career group leaders: apply by 30 Jan to become a FENS-Kavli Network Scholar and connect, collaborate, and contribute to shaping neuroscience in Europe.
rb.gy/havqur
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reposted by
Nikos Konstantinides
Giselle Cheung
about 1 month ago
⚡️Funded PhD position in my lab in Exeter 🧠 @exeter.ac.uk If you are interested in brain development, cell-type diversity, neuroglia, subcortical structures and neurodevelopmental disorders, check out this opportunity. Deadline 28 Feb. Please RT🙏.
www.exeter.ac.uk/study/fundin...
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PhD Funding: Subcortical brain deve | University of Exeter
The University of Exeter’s Department of Clinical and Biomedical Sciences is inviting applications for a PhD studentship to commence on September 21st, 2026 or as soon as possible thereafter.
https://www.exeter.ac.uk/study/funding/award/?id=5796
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reposted by
Nikos Konstantinides
Dafni Hadjieconomou
about 1 month ago
📣First preprint of the lab📣 Did that really happen?😅 Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
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Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity
Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...
https://www.biorxiv.org/content/10.64898/2026.01.09.698651v1
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I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
add a skeleton here at some point
about 1 month ago
23
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63
reposted by
Nikos Konstantinides
Sergi Roig Puiggros
about 1 month ago
I'm very excited to finally see this one out in
@natneuro.nature.com
! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n
www.nature.com/articles/s41...
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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience
Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...
https://www.nature.com/articles/s41593-025-02142-7
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Very happy for this
@ejneuroscience.bsky.social
editorial on the importance of diverse research animals in neuroscience. We make the case that embracing a plurality of model organisms enriches the field and accelerates both basic and translational research.
onlinelibrary.wiley.com/doi/10.1111/...
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https://onlinelibrary.wiley.com/doi/10.1111/ejn.70384
about 1 month ago
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reposted by
Nikos Konstantinides
Federation of European Neuroscience Societies - FENS
2 months ago
🏃 A heads-up for the
#FENS
community!
#FENS
will take part in the Brussels 20K, with a dedicated team running and walking in support of FENS activities! 🌟 👉 Find out more information here:
buff.ly/49gkN7D
👉 Team registration form:
buff.ly/dGwCs6K
Stay tuned for more updates!
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reposted by
Nikos Konstantinides
Matthew L. Kraushar
2 months ago
come check out what we're cooking here! 📣 early career neuroscience researchers in europe 📣 this will be prior to FENS 2026 in Barcelona - have a look 😎
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reposted by
Nikos Konstantinides
Young PI Neuroscience Symposium'26
2 months ago
📢Are you a young PI or senior postdoc in neuroscience looking to embark on the challenging journey of starting your own lab? 📆Then save July 5, 2026 in your calendar and join us in Barcelona for the second Young PI Symposium.
youngpisymposium2026.com
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Young PI Symposium 2026
Visit the post for more.
https://youngpisymposium2026.com
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reposted by
Nikos Konstantinides
Max Farnworth
2 months ago
New paper covering what we think is a pretty nice and comprehensive overview over tools suitable for neuroethology in butterflies and moths. Also, check out the whole special issue if you're an insect neuroethologist.
@neuroethology.org
@dzg-neurobiology.bsky.social
doi.org/10.1007/s003...
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Emerging tools to advance neuroethology in butterflies and moths - Journal of Comparative Physiology A
Journal of Comparative Physiology A - Butterflies and moths have played historically important roles in developing our understanding of both ecology and evolutionary biology, and neuroethology. In...
https://doi.org/10.1007/s00359-025-01785-y
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reposted by
Nikos Konstantinides
Lisa Genzel (she/her)
2 months ago
Share and apply!
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Congrats Bassem - very well deserved!
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2 months ago
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reposted by
Nikos Konstantinides
Georgia Rapti
4 months ago
I’m proud to have helped launch the
#PITraining
survey of FKNE
@fkne-scholars.bsky.social
We ask PIs to share what really matters for effective research leadership. Your feedback = better support, better science. Take part or share:
fenskavlinetwork.org/fkne-pi-surv...
Deadline: 29 Dec 2025
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Nikos Konstantinides
Dafni Hadjieconomou
3 months ago
Apply for a PhD in Paris!! A project to come and work with me and my team at the GutSense lab included in the list! 🪰🧠⛽
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Cool preprint from the lab of Raouf Issa at ESPCI in Paris with a small contribution from our lab at
@ijmonod.bsky.social
Padmanabhan et al found that a specific set of Drosophila dopamine neurons, which is already active in embryos and stays functionally important for locomotion throughout life.
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3 months ago
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reposted by
Nikos Konstantinides
Thibaut Brunet
3 months ago
Having witnessed many HHMI labs during my postdoc, my impression was that many of them struggled to even productively spend all their money. At some point it seems logical that you just hit diminishing returns; systematic studies have come to the same conclusion.
www.science.org/content/blog...
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Research output as a function of grant support: The scatter matters
https://www.science.org/content/blog-post/research-output-function-grant-support-scatter-matters
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Nikos Konstantinides
Luisa F. Pallares
3 months ago
***Super cool-project alert***⚠️ Come work with
@dirkmetzler.bsky.social
and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by
@dfg.de
@gevol.bsky.social
)
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Paris in the top-5 bike-friendly cities in the world ❤️
www.paris.fr/pages/paris-...
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Paris rentre dans le top 5 des villes cyclables
La capitale française décroche la 5e place mondiale dans l’index international des villes cyclables du cabinet Copenhagenize. Paris est en 2e position pour la qualité de son infrastructure cyclable.
https://www.paris.fr/pages/paris-rentre-dans-le-top-5-des-villes-cyclables-33074??utm_source=newsletter&utm_medium=email&utm_campaign=s30
3 months ago
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reposted by
Nikos Konstantinides
3 months ago
Call for junior or mid-career group leaders in neuroscience! Apply by 30 Jan to join the FENS-Kavli Network. We are looking for excellent and engaged future scholars who are committed to exchanging scientific ideas & improve neuroscience in Europe.
fenskavlinetwork.org/who-we-are/a...
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Fellow neuroscientists, consider applying and reach out if you have any questions!
fenskavlinetwork.org/who-we-are/a...
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3 months ago
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reposted by
Nikos Konstantinides
Lisa Genzel (she/her)
3 months ago
Junior or mid-career group leaders working in neuroscience, apply by 30 Jan to join the FENS-Kavli Network! We are looking for excellent and engaged future scholars, committed to exchanging scientific ideas & contributing to improve Neuroscience in Europe.
rb.gy/havqur
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Application procedure – FKNE
http://rb.gy/havqur
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This👇is a balanced view
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3 months ago
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“Send it to Current Bio”
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4 months ago
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reposted by
Nikos Konstantinides
Ishier Raote
4 months ago
#MembraneTraffickers
! Our next online seminar is this Thursday, Nov 6 at 5 PM CEST! We’ll hear from
@agatawitkowska.bsky.social
on mechanical control of neurotransmission and
@abdourachidthiam.bsky.social
on lipid storage mechanisms in health and disease. Spread the word and join the discussion!
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It's 2025. The world is going to shit and, in Greece, people get killed over football teams. A sense of despair not only about the present but also about the future.
4 months ago
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Nikos Konstantinides
Vincent J Lynch 🐘🦣🦥 🦇🐋🐢🐍
4 months ago
50 years ago, King & Wilson published a foundational paper that underlies the cis-regulatory paradigm (CRP) of
#DevoEvo
#EvoDevo
, i.e., that *almost* all morphological evolution is driven by mutations in regulatory elements, rather than proteins, and it all arose from simple misunderstanding 🧪 🧵
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Nikos Konstantinides
Thomas Balan
4 months ago
🚨 Excited to share my first preprint on bioRxiv! 🎓 We uncover a non-canonical role of condensin I, beyond chromosome segregation 🧬 This work is the fruit of a collaboration between the
@sandraduharcourt.bsky.social
&
@betermieri2bc.bsky.social
labs! ➡️
doi.org/10.1101/2025...
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A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination
Prokaryotes and eukaryotes use diverse strategies to cope with invading mobile genetic elements, including programmed DNA elimination (PDE). In the ciliate Paramecium , elimination of transposable ele...
https://doi.org/10.1101/2025.10.03.680307
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Nikos Konstantinides
Ella Preger 🎗️
4 months ago
Check out our new preprint on the evolution of enhancer loss. Turns out there are 50 ways to lose a function. We found four of them.
www.biorxiv.org/content/10.1...
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Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution
The evolutionary loss of morphological traits is often driven by changes in gene regulation. Many developmental genes are controlled by multiple, redundant enhancers, raising the question of how robus...
https://www.biorxiv.org/content/10.1101/2025.10.27.684981v1
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Nikos Konstantinides
Junior European Drosophila Investigators
4 months ago
Preparations for the next JEDI meeting are underway! The upcoming Junior European
#Drosophila
Investigator /
#NewPI
meeting is planned for Portugal in June. Final dates and additional details will be announced soon - stay tuned for updates!
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reposted by
Nikos Konstantinides
Maxim Greenberg
4 months ago
Spread the word! There is a professor position opening at our University
@upcite.bsky.social
. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
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Nikos Konstantinides
PLOS Biology
4 months ago
How do pleiotropic TFs generate organized diversity in developing tissues?
@spinalorga.bsky.social
shows that PAX3 & PAX7 organize
#SpinalCord
by acting as both repressors & pioneer activators, regulated by
#morphogens
to ensure precise neural subtype specification
@plosbiology.org
🧪
plos.io/4qumsla
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Aabel Aaberg and Zyra Zywiec are celebrating!
add a skeleton here at some point
4 months ago
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reposted by
Nikos Konstantinides
Emília Santos
4 months ago
New preprint led by the brilliant
@aleksandra-marconi.bsky.social
on cichlid brain diversification, fgf8a signalling and regulatory divergence with TEs on the mix! All part of a wonderful collaboration with
@ebablab.bsky.social
www.biorxiv.org/content/10.1...
@camzoology.bsky.social
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In Donostia, teaching myself some Basque
4 months ago
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reposted by
Nikos Konstantinides
4 months ago
Our latest paper on a histone methyltransferase-independent function of PRC2 controlling small RNA dynamics during programmed DNA elimination in Paramecium is now published in
#NAR
.
#RNAbiology
#TEsky
#smallRNAs
#PRC2
#DNAelimination
1/5
academic.oup.com/nar/article-...
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A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium
Abstract. To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms
https://academic.oup.com/nar/article-abstract/doi/10.1093/nar/gkaf1048/8287599?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email
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reposted by
Nikos Konstantinides
Yad Ghavi-Helm
4 months ago
Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by
@mmasoura.bsky.social
, to find out!
www.biorxiv.org/content/10.1...
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Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
https://www.biorxiv.org/content/10.1101/2025.09.23.678065v2
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reposted by
Nikos Konstantinides
Richard Benton
4 months ago
I'm looking to recruit a post-doc to help push forward our growing interests in insect ecotoxicology. Apply here by Nov 30th! (thanks for reposting)
career5.successfactors.eu/sfcareer/job...
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Career Opportunities: Posdoctoral researcher in toxin susceptibility and evolution of resistance in insects (22517)
https://career5.successfactors.eu/sfcareer/jobreqcareer?jobId=22517&company=universitdP
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