Had so much fun at Pint of Science last night. Brilliant talk from Holly Gregory. If you missed out last night there’s another night of talks tonight!

Join our team at the London @pintofscience.uk events. You'll get to hear from @caswell.bsky.social and Holly Gregory about how the body works! Still a few tickets for tomorrow! Book now! pintofscience.co.uk/event/maps-m...

We have several events that are part of the Pint of Science event series. If you're free this week check out our academics. You won't regret it! pintofscience.co.uk/event/maps-m...

If you're in London on Tuesday and fancy an evening of science and beers (who doesn't?!) come along to the Pint of Science night that I'm organising. There are also events on the 18th and 20th if you can't make this one. See you there! pintofscience.co.uk/event/maps-m... @pintofscience.uk

I'm hosting a #PintOfScience night on the 19th May! Come along for a fun evening with awesome talks from UCL's @caswell.bsky.social and Holly Gregory! @ucllifesciences.bsky.social pintofscience.co.uk/event/maps-m...

⚠️New review straight out of the oven! "Spatial navigation in preclinical Alzheimer's disease: A review" arxiv.org/abs/2603.23082 We focus on spatial navigation as a sensitive cognitive marker in preclinical AD, compiling evidence from cognitively unimpaired individuals with positive AD biomarkers.

Thanks for the feature @ucllifesciences.bsky.social! I plan to let the fame go straight to my head 🧠👩‍🔬

Really interesting from the Burgess stable — theta sweeps in entorhinal cortex show a dorsoventral gradient, with different spatial scales coordinated at different frequencies. Nice work @zilong-ji.bsky.social @neilburgess10.bsky.social 👏 biorxiv.org/content/10.1101/2026.03.08.710351v1

Thanks Caswell! Happy to see this out. Recent interesting work from Vollan et al @azvollan.bsky.social showed that the decoded locations from grid cell activity sweep out in a left-right alternative way across successive theta cycles, steered by an “internal direction” signal in parasubiculum.

Human hippocampal theta–gamma coupling coordinates sequential planning during navigation Impressive study from Dan Bush's Lab at UCL: www.pnas.org/doi/10.1073/...

What drives the sequential emergence of spatial neurons in developing rats? In our ICLR 2026 paper, we show how changes in movement statistics drive spatial tuning. Our model replicates experimental timelines and predicts novel conjunctive tuning maturation. doi.org/10.64898/2025.12.30.696864

So happy to finally see this out in @currentbiology.bsky.social! We found that disrupted replay structure in an AD model was linked to reduced place cell stability and more repetitive behaviour on a radial maze 🧠 @abrate.bsky.social @caswell.bsky.social #neurosky tinyurl.com/yx52vzjd

Memory dysfunction in Alzheimer’s disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice led by Dr Sarah Shipley @shipleysj.bsky.social and Prof Caswell Barry @caswell.bsky.social @ucllifesciences.bsky.social

Wooo! Exciting news - Inside Your Brain - the children's neuroscience book I wrote with @lucyannunwin.bsky.social has been listed in the 2025 Children's book of the year shortlist. Please vote for us: tinyurl.com/yhr8vawe (some of those other books look amazing too)

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky 1. The importance of stupidity in scientific research Open Access journals.biologists.com/jcs/article/...

OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019). The renamed: Bluesky-sized history of neuroscience (biased by my interests)

Excited to share that our preprint is out! doi.org/10.1101/2024... The structure of place cell reactivations was disordered in AD mice compared to WT! This was predictive of reduced place cell stability and memory performance on a radial-arm maze task. Here are a few details: 1/5🧵

Our latest preprint has landed www.biorxiv.org/content/10.1... Fantastic work from @laurenb29.bsky.social and Will de Cothi showing how many of the cell types associated with subiculum (e.g. boundary vector cells, corner cells) can be understood as successor features. TLDR: SUB not CA1 is the SR

Huge congrats to @karyna-mi.bsky.social for her paper published today in Science! She found that the hippocampus is really important for a key strategy we use to make decisions called hidden state inference! 🧪 🧠https://www.science.org/doi/10.1126/science.adq5874 1/7

What are the brain’s “real” tuning curves? Our new preprint "SIMPL: Scalable and hassle-free optimisation of neural representations from behaviour” argues that existing techniques for latent variable discovery are lacking. We suggest a much simpl-er way to do things. 1/21🧵