Microglia checkpoints promote healthy myelin aging Our new paper is out in Nature Neuroscience @natneuro.nature.com www.nature.com/articles/s41... 🧵1/3

Research Spotlight 💡 New study shows #astrocyte reactivity in #Alzheimers depends on activated #microglia. PET imaging & biomarkers reveal microglia drive Aβ-linked astrocyte reactivity, tau pathology, and cognitive decline. 🔗 https://www.nature.com/articles/s41593-025-02103-0

Happy new year! 🎉 Don’t miss the second UK Glia meeting, 8–9 June 2026! Registration open now, abstracts close 16 Jan. 🔗 www.physoc.org/events/uk-gl... In this post, meet Philip Hasel @philiphasel.bsky.social from UK DRI @ukdri.ac.uk and the University of Edinburgh @edinburgh-uni.bsky.social

Very happy to have contributed to this wonderful/tentacular work alongside so many amazing colleagues and friends! It opens up new ways of understanding grey matter heterotopia associated with altered cortical function and #epilepsy in humans. 🧠🧪🔥 www.nature.com/articles/s41...

On Dec. 29, airstrikes impacted an area near Doctors Without Borders healthcare facility in Lankien, #SouthSudan. In response to the deteriorating security situation, MSF evacuated key staff, though the facility remains operational and continues providing essential medical care.

Review @jem.org @uwmadison.bsky.social The cribriform plate: A dynamic central nervous system–immune hub rupress.org/jem/article/...

Wishing everyone a peaceful and happy year. I’ll be joying,listening, learning… and hopefully celebrating a PhD acceptance as a bonus. 🥳💜🫶🏻Happy new year everyone 🫶🏻💙🥳

Remodeling of skull bone channels regulates immune infiltration into the meninges during neuroinflammation: Immunity www.cell.com/immunity/ful...

Remodeling of skull bone channels regulates immune infiltration into the meninges during neuroinflammation @cp-immunity.bsky.social @ciml.bsky.social @eemescolan.bsky.social www.cell.com/immunity/ful...

Just out in Lancet Neurology www.thelancet.com/journals/lan...

Nonrestorative sleep may signal impaired glymphatic clearance, allowing metabolic waste to accumulate and chronically prime microglia toward a proinflammatory, disease vulnerable state a striking neuroimmune link between sleep quality and brain health. academic.oup.com/brain/advanc...

𝗧𝗵𝗲 𝗘𝗻𝘁𝗮𝗻𝗴𝗹𝗲𝗱 𝗕𝗿𝗮𝗶𝗻 Annual reminder that the book is open access. How do we think of the brain as a deeply interconnected system with highly distributed, non hierarchical processing. Want to learn about the brain from a fresh perspective? #neuroskyence mitpress.mit.edu/978026254460...

Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesis @cp-immunity.bsky.social

COVID-19 associated neurological and psychological manifestations www.nature.com/articles/s41...

#Parkinsons -associated alpha-synuclein co-pathology drives tau accumulation in #Alzheimers patients & iPSCs-derived models alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

No matter our beliefs, Jesus’ message of opening our hearts to those who are different from us has never felt more important than this Christmas. I want to wish everyone celebrating in London and around the world a very Merry Christmas.

Behavioral Scientist’s Notable Books of 2025 behavioralscientist.org/behavioral-s... via @behscientist

This Christmas, we’re choosing togetherness over perfection. Holding space for family, friends, carers, and everyone living with chronic illness. Be gentle with yourself. You are seen, supported, and not alone. 💜 #MerryChristmas

Sterile Innate Immune Mechanisms in Neurodegenerative diseases www.jbc.org/article/S002...

Our lab has 2 new papers in the current issue of @painthejournal.bsky.social: The first study, by Georgia Hadjis, shows that motivational conflict, rather than resource competition, determines priority assignment when pain is concurrent to competing demands. journals.lww.com/pain/fulltex...

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵 rdcu.be/eVZ1A

25 Kasım Kadına Yönelik Şiddetle Uluslararası Mücadele Günü yaklaşıyor "Faşizmin inşa edilmeye çalışıldığı şu günlerde kadınların her yan yana gelişi, her örgütlenme çabası demokrasi mücadelesinin de önemli bir parçası ve dayanağı" is.gd/dqCyUN

Visit LaborOnline to catch Ian Rocksborough-Smith's interview with Naomi R Williams on their recent book, 'A Blueprint for Worker Solidarity: Class Politics and Community in Wisconsin.' lawcha.org/2025/12/10/n...

I finally got some time to flesh out my rant about these headlines... TL;DR: age differences ≠ aging jenndowd.substack.com/p/does-adole... #demography #episky #medsky #neurosky

In 2025, MSF continued to respond to some of the world’s most urgent crises. This selection of photos from the past year captures both breaking points and moments of resilience among the people we assist and our staff. View the full photo story: https://ow.ly/cqhA50XNenE

Just finished this thrilling, vulnerable, and inspiring book on friendship, loss, addiction, resilience, and editing memories by Prof Steve Ramirez. Neuroscientists and neuroscience enthusiasts should enjoy this one.

Here’s a snapshot of the services MSF provided in #Gaza in 2025. We’ve received no updates on our Israeli registration process for 2026 and it is unclear if we will be able to continue activities. - 800,000 consultations - 22,700 surgical operations - 700 million litres of water

Immune-brain plasticity underpins stress and affective behaviors: @cp-neuron.bsky.social www.cell.com/neuron/fullt...

Trump and DOGE gutted US science: Scientists from a variety of fields researching anything from chemical hazards, drug addiction, pollution, LBTQ health care & paediatric brain disease report how grants were withdrawn and and they struggle to support students, staff and research 🧪

Product Citation: Neuroimmune activation is an early marker of Parkinson’s disease pathology. Exogenous uptake of oligomeric #AlphaSynuclein by cortical microglia was visualized using StressMarq’s Kinetically-Stable #aSyn Oligomers. Paper ⚡ https://bit.ly/4gW8ZOG Product ☀️ https://bit.ly/491ImDG

🧠 Why it matters 🧠 -The results challenge a prevailing view that 5‑HT2A activation alone drives psilocybin’s therapeutic actions. -Highlights the importance of polypharmacology 🥳, and points to the 1B receptor as a target for non‑hallucinogenic antidepressant and anxiolytic pharmacotherapies.

netneurotools: a trainee-oriented approach to network neuroscience | doi.org/10.1101/2025... Our lab’s internal toolkit for accomplishing everyday tasks in brain imaging ⤵️

Just wrapped up the CAJAL Advanced Neuroscience Training Programme in Bordeaux! 🍷🧠 It was a privilege to introduce such a brilliant group of students to the world of #Neuroimmunometabolism. The future of our field looks very bright! #Neuroscience #Immunology #Cajal #Bordeaux tinyurl.com/276b6upe

Please share the next "Neural Circuits of behavior" school in #Pisa, organised by @biancasilvalab.bsky.social We will be exploring how #neuroplasticity shapes the #brain and #cognition 🧠 #NeuroSky #Neuroscience ⚠️ Applications and #scholarships are open until 15/01/26 ⚠️ www.sns.it/it/evento/ne...

This is a very new study and needs to be replicated further, but I found it interesting. As a physiotherapist and neuroscientist, what caught my attention more was whether this alleged epigenetic change on the mitochondria has an effect on infants' brain health, www.cell.com/cell-metabol...

I think everyone involved in neuroimmunology/psychoneuroimmunology should read this article; it is really beautifully written. It is wonderful how it lays out the things that are neatly organised in your mind before your eyes. www.nature.com/articles/s41...

Ever wanted to know how the visual system of a long distance migratory moth looks like? Then you'll find your answers in our new paper. Finally out, after about a decade of collecting data by a group af amazing co-authors. Find it here, open access: link.springer.com/article/10.1...

ATgliaNet Symposium 2026 March 20th, 2026 | Vienna Keynote speaker Prof. Leda Dimou (University of Ulm) Registration & abstract submission until Feb 13: https://loom.ly/33SkUKk Find more glia related meetings here: https://loom.ly/dwKZ1r8

This study develops human pluripotent stem cell derived 3D neural organoid models that recapitulate sympathetic ganglion development and function, enabling the study of peripheral nervous system maturation, target organ innervation, and related diseases. www.cell.com/cell-stem-ce...

AD genetic risk links microglial immunity and cholesterol. Our new BioRxiv study identifies CH25H-derived 25-HC as a toxic lipid downstream of cGAS–STING–IFN that drives tau spread, inflammation, and neurodegeneration, offering a tractable therapeutic pathway. www.biorxiv.org/cgi/content/...

Join Dr Fiona McLean, @ianharrisonneuro.bsky.social, @sorayam.bsky.social & Dr Kate Harris for a festive podcast special where they share their lab mishaps, admin chaos, and lessons learned from experiments that went wrong but taught them the most. pod.fo/e/3698bd

Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess. Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq. Preprint: www.biorxiv.org/content/10.6...

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation. Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

If the “alpha males” think shaming women online will bring back the world they miss… they’re gonna need a bigger anthill. My new post: “Just look at the degree on that chick.” strongsilenttype.net/2025/11/22/j...

A new Nature study reveals that a lesion remote astroglial subtype can actively reprogram microglia to clear myelin debris and promote whitematter repair uncovering a CCN1 mediated astrocyte microglia axis that enhances functional recovery after spinal cord injury www.nature.com/articles/s41...

A paper from my PhD lab is on Science! This is a really cool new way to utilize EM connectome datasets. Congrats to the team! www.science.org/doi/10.1126/...

New research reports that GPNMB is secreted in response to lysosomal stress via lysosomal exocytosis & highlights the #Parkinsons disease risk factor LRRK2 as a strong modulator of GPNMB secretion; A biomarker of lysosomal stress? www.science.org/doi/10.1126/...

Great opportunity for junior/mid career neuroscientists in Europe! Do apply!

My first paper just got published last week! *Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p* elifesciences.org/articles/107...