For the first time, we hosted a CNRS Unusual Visits event: 290 applications → 24 visitors→ A tremendous enthusiasm!! Highlights included immune system talks & hands-on workshops on skin, cholesterol, IgE, and DNA extraction.

🔬 A look back at the 2025 Science Festival in CIML! On Thursday 9 October, we had the pleasure of opening the doors of our laboratories to middle and high school students as part of the 2025 Science Festival. A day rich in discoveries and exchanges! #FêteDeLaScience #FDS2025

🔬 The CIML is proud to be an academic partner of the 11th edition of #MiFoBio2025, the Functional Microscopy in Biology school organized by @gdrimabio.bsky.social taking place from October 10–17, 2025. The CIML Imaging Platform and researchers will be sharing our expertise in immune system imaging.

A new study led by Sandrine Henri is out now in OncoImmunology. Authors characterized the prostate's immune landscape in healthy inidviduals and during cancer progression. Congratulations to 1st author Despoina Pervizou and all collaborators.

A new study led by Elena Tomasello & Marc Dalod is out now in @natimmunol.nature.com. Through the generation of a novel system lacking plasmacytoid DCs, authors show that pDCs are dispensable or deleterious in respiratory viral infections. Congrats to 1st author Clemence Ngo and all collaborators!

Today we had the great honor to welcome Dr Michela Locci from the University of Pennsylvania in our CIML seminar series. Michela gave an outstanding seminar entitled "Defense decoded: how mRNA vaccines train germinal center responses" and had great exchange with CIML scientists.

It was a pleasure to have Ang Cui presenting her work at CIML.

Today we had the great honor to welcome Dr Florent Ginhoux from Gustave Roussy Institute in our CIML seminar series. Florent gave an outstanding seminar entitled "Harnessing Tumor Macrophage Heterogeneity" and had great exchange with CIML scientists.

Today we had the great honor to welcome Dr Megan MacLeod from the University of Glasgow School of Infection and Immunity. Megan gave a great talk on"Different faces of immune memory in the lung following influenza virus infection" and had great exchange with CIML scientists. Thanks for visiting us!

Today we had the great honor to welcome Dr Ed Roberts from the Cancer Research UK-Scotland Institute @cruk-si.bsky.social. Ed gave a great talk on"Time dependent impact of viral infection on lung tumour development" and had great exchange with CIML scientists. Thanks Ed for visiting us!

Today we had the great honor to welcome Dr Francesca Granucci from the University of Milano-Bicocca in our CIML seminar series. Francesca gave an outstanding seminar entitled "Microbial adhesion promotes mechanotransduction to initiate innate immunity" and had great exchange with CIML scientists.

🗞️ La Provence newspaper dedicated an article to Réjane Rua's work and career on August 6th, highlighting her expertise and remarkable studies at CIML. Check here:

Big congratulations to Achille Broggi @achillebro.bsky.social, team leader at CIML, who has been awarded the 2025 CNRS Bronze Medal! This distinction honors his research on innate immunity, particularly his discoveries on the role of interferons in tissue protection and repair.

The CIML mourns the loss of its founding father, Michel Fougereau. In 1976, he founded our institute to bring immunology researchers in France together on one site. Generations of immunologists were shaped by what he built. His legacy lives on in the curiosity and collaboration that define CIML.

Last week we had the great honor to welcome Dr Maria Rescigno from Humanitas Research Hospital in our 2025 CIML seminar series. Maria gave an outstanding seminar on "The microbiota in pregnancy outcome and risk of sepsis in the newborn" and had lots of great exchange with CIML scientists.

Last week we had the great honor to welcome Dr Nuria Martínez-Martín from Severo Ochoa Molecular Biology Centre in our 2025 CIML seminar series. Nuria gave a brillant seminar on "Mitochondria as Gatekeepers of B Cell Function: Internal Regulators and External Gifts" Thanks Nuria for visiting !

Yesterday, we had the pleasure to welcome Dr. Vera Pancaldi from Centre de Recherche en Cancérologie de Toulouse in our CIML seminar series. Vera gave a brillant seminar on "Data-driven mathematical models for simulating the tumour microenvironment" Thanks for visiting @verapancaldi.bsky.social !

Last week we had the great honor to welcome Pr. Ping-Chih Ho from University of Lausanne and Ludwig Cancer Research in our 2025 CIML seminar series. Ping-Chih gave a brillant seminar on "Mitochondria-tailored T cell dysfunction and opportunity for cancer immunotherapy" Thanks for visiting !

Last week we had the great honor to welcome Pr. Tal Arnon from University of Oxford in our 2025 CIML seminar series. Tal gave an outstanding seminar on "Humoral immunity in the infected lung" and had lots of great exchange with CIML scientists. Thanks for visiting !

Check this last paper from the Malissen's lab👇. A gain-of-function CARMIL2 variant can substitute for CD28 costimulation, enabling T cells to bypass PD-1 and CTLA-4 checkpoints. This discovery revisits the architecture of the CD28 costimulatory pathway and opens avenues for next-gen immunotherapies.

🦠 Check the last study from the team of Philippe Pierre in PNAS @pnas.org. The authors show how a bacterial toxin can hijack our cells’ stress response to trigger immune signals linked to inflammation and infection. Congratulations to all authors!

Last week we had the great honor to welcome Dr. Eliane Piaggio from Institut Curie in our 2025 CIML seminar series. Eliane gave an interesting seminar on "Single-Cell Treg Profiling: New Cancer Therapies and Insights into Tumor-Treg Biology" and had great exchanges with CIML scientists.

🧠🦠 Check this Review written by the team of Sophie Ugolini @ugolinis.bsky.social on how sensory neurons modulate immune responses. Just out in Immunity @cp-immunity.bsky.social.

🔬 🦠 Check this great scientific meeting organized by Carolyn King and CIML's team leader Mauro Gaya. @immunologyking.bsky.social @maurogaya.bsky.social

🧠🛡️ CIML celebrates the International Day of Immunology 2025: When Brain Meets Immunity. This year, we spotlight two Inserm researchers whose research is transforming our understanding of how the nervous and immune systems interact, paving the way for new therapies for neurological diseases.

🎉 We're thrilled to share that Dr. Anaïs Rogier, trained at CIML in Sophie Ugolini’s team, has received the Aix-Marseille University Thesis Award for her outstanding work on neuro-immune regulation during viral infections. Bravo Anaïs! 🧠🦠

In a study led by Jean-Pierre Gorvel and Sylvie Mémet, CIML researchers found that SLAMF receptors shape human plasmacytoid dendritic cell responses to intracellular bacteria. Congrats to 1st author Joaquin Pellegrini and collaborators. www.jci.org/articles/vie... @jclinical-invest.bsky.social

We are proud to announce that Prof. Eric Vivier @ericvivier.bsky.social, team leader at CIML and former director (2008–2017), has been awarded the prestigious Léopold Griffuel Prize for "Translational and Clinical Research" by the ARC Foundation for Cancer Research. @univ-amu.fr @inserm.fr @cnrs.fr

Today, we had the pleasure of welcoming Dr. Iñaki Martin Subero from Fundació de Recerca Clínic Barcelona in Spain as part of the 2025 CIML seminar series. Iñaki gave an incredible seminar: “An epigenetic journey to the origin, pathogenesis and evolution of chronic lymphocytic leukemia”.

Yesterday we organized the CIML Scientific Day dedicated to "Immunology Meets Oncology" The day featured outstanding presentations on the intersection between immunology and cancer research from Bruno Quesnel, Pierre Milpied, Nathalie Auphan-Anezin, Eric Vivier, Carole Siret, and Rafael Argüello.

Today, we had the pleasure of welcoming Dr. Jakub Abramson from the Weizmann Institute of Science, as part of the 2025 CIML seminar series. Jakub gave a great seminar: “From Thymic Mysteries to Sex hormones - HECking the sexual dimorphism of the immune response” Thanks Jakub for your visit!

Check this last study led by Nathalie Pujol on skin damage in C. elegans 🪱 just published in PLOS Genetics 👇

Today, we had the pleasure of welcoming Dr. Filipe Pereira from Lund University in Sweden, as part of the 2025 CIML seminar series. Filipe gave an incredible seminar on "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy". Thanks Filipe for your visit!

🔬 🦠 Check this great scientific meeting organized by Wolfgang Kastenmueller, Menna Clatworthy and CIML's team leader Marc Bajenoff.

We are proud to announce that the AIR-MT project has been selected for funding by Inserm ImpactSanté program (€3M), with CIML researcher Béatrice Nal as a key partner. The project will use artificial intelligence to design optimized RNAs for more effective vaccines and therapies. #France2030.

We are proud to announce that the ANTIBAX project has been selected for funding by Inserm (€2.3M), with CIML team leader Pierre Milpied as main partner. Pierre’s team will identify antibodies in tumors that target cancer-causing bacteria, paving the way for new treatments against mucosal cancers.

Today, we had the pleasure of welcoming Dr. Nelson Gekara from the Institute of Microbiology and Hygiene in Freiburg, as part of the 2025 CIML seminar series. Nelson gave a fantastic talk on "The cross-talks between the innate immune and DNA repair system". Thanks Nelson for your visit!

Today, we had the pleasure of welcoming Dr. Steeve Boulant from the University of Florida, as part of the 2025 CIML seminar series. Steeve gave a great talk on "Type III Interferons: from regulation of antiviral response to promoting barrier function". Thanks @boulantlab.bsky.social for your visit!

✊ ♀️ 👩‍🦳 #8mars | À l'occasion de la #JournéeDesDroitsDesFemmes demain, découvrez 10 portraits de femmes travaillant au @cnrs.fr en Provence et qui ont été mises à l'honneur et distinguées lors des derniers mois.

The CIML supports the movement #StandUpForScience2025 and expresses its solidarity with scientists working in the United States, where academic freedom is currently being challenged. Gather at 12:00 pm at the Natural History Museum, Palais Longchamp, Marseille. @cnrs.fr @inserm.fr @univ-amu.fr

Today, we had the honor of welcoming Dr. Kim Good Jacobson from Monash University, Melbourne, to kick off the 2025 CIML seminar series. Kim gave a brilliant talk on "Molecular Regulation of Antibody and Immune Memory Responses to Viral Infections". Thanks @kimljacobson.bsky.social for your visit!

Today, we celebrate International Women’s Day in Science. To honor this day, we've created seven portraits of ♀️ scientists at CIML. Each portrait reflects their unique journey and contributions. Stay tuned for their inspiring stories. #WomenInScience @inserm.fr @cnrs.bsky.social @univ-amu.fr

The team of Pierre Milpied at CIML, in collaboration with Amédée Renand and Sophie Conchon's teams in Nantes, studied circulating autoreactive T cells in patients with autoimmune hepatitis by single cell RNA-seq and identified tissue-imprinting signatures. Check the study: @naturecomms.bsky.social.

In a study led by Sylvie Mémet and Jean-Pierre Gorvel, CIML researchers identified a new pathway by which Brucella abortus escapes host immune responses in the visceral fat. Congrats to 1st authors Joaquin Pellegrini, Gabriela González and all collaborators. Check the study: @naturecomms.bsky.social

The team of Pierre Milpied has just released a new method that links single-cell RNA sequencing with monoclonal antibody production: FB5P-seq-mAbs. This innovation provides a robust and cost-effective way to study B cell responses and rare populations. www.frontiersin.org/journals/imm...

Last week we had the great honor to welcome Dr. Cecilia Johanssen from Imperial College London in our CIML seminar series. Cecilia gave a brilliant seminar on "Type I interferons in respiratory viral infections and lung cancer" and had lots of exchange with CIML scientists.

We are proud to announce that two of our distinguished immunologists, Bernard Malissen and Eric Vivier, have been recognized as Highly Cited Researchers by @clarivate.com , with research publications ranking in the top 1% of citations in their field over the past decade.

@irlalab.bsky.social and collaborators reveals that RANKL therapy reverses age-related thymic decline, recovering immune health in older adults by restoring youthful T-cell responses to vaccines and tumors. Check their study in Science Translational Medicine. www.science.org/doi/10.1126/... .

Welcome to the BlueSky account of the Centre d’Immunologie de Marseille-Luminy (CIML). 🌟 Founded in 1976, we’re one of Europe’s largest and most prestigious immunology research centers, located in the heart of the Calanques National Park. 🏞️