Ooh - my new paper on case study is out! What’s a case study, how do you do one, how do you spot a good one? Includes niche examples like the REF impact case study (though it’s mainly about research case studies).

This is very exciting! A small clinical trial using gene therapy for Huntington's disease has been successful. microRNAs were used to edit the Huntington mRNA, stopping it making mutant protein that can damage neurons. Huge hopes now for treating such a devastating condition

As paper titles involving TB go, this one using the rhyming Fc is not bad... (also a good synopsis of an important paper) #IDSky #TBSky #immunosky www.science.org/doi/10.1126/...

IMPORTANT 🧵 We've been seeing how RFK Jr & anti-vax lobby has been steadily and effectively reducing access to vaccines in the US. But it could happen in UK too. It's a threat worth considering given Malhotra's speech at Reform conf & big overlap between anti-vax and RW populsim. Read on! 1/11

Front page of @apnews.com calling it like it is. These claims are unfounded. #VaccinesSaveLives #TylenolisSafe #Tylenol #FireRFK #MedSky #Vaccines

So the politicisation of health continues in the States and I want to highlight a few key things 🧪🧵

“Don’t pay any attention to what Trump says about medicine’, Wes Streeting tells Britons”

So the politicisation of health continues in the States and I want to highlight a few key things 🧪🧵

I was curious, and it took five minutes to find this. A lot of the data is US, plus Sweden. Superficially looks a larger sample set and the conclusion is the opposite. I am sure you will understand all this a lot better than I do. I am sceptical of scepticism! bsky.app/profile/mick...

The ITV exposé on COVID now turns its sights on testing. I was stunned in 2020 when Sir Paul Nurse - Director of the Francis Crick Institute - told me he’d written to the government to offer the services of the Crick (the biggest biomeolecular lab in the country) - and never got a reply…

I find the politicisation of autism spectrum disorder extremely troubling. Paracetamol or Tylenol as it is called in States should not be touted as a cause of ASD before anyone has scrutinised the data they allege will show this. 🧪🧵

So much history captured in these single images

Kennedy’s inexperienced and under-qualified ACIP continues to make a mockery of science based evidence with confusion regarding what they were voting for, actions such as changing votes, pushing other votes down the line, use of anecdotes versus science and ambiguous decisions…🧵

I watched the 1st meeting day of RFK Jr’s handpicked committee of vaccine advisors. It was utterly depressing. 1/

New in @science.org: "Together, these results suggest that long-term #ketogenic diets leads to multiple aberrations of metabolic parameters that caution their systematic use as a health-promoting dietary intervention." #keto #lowcarb #medsky #cardiosky #diabetes www.science.org/doi/10.1126/...

Important study (that rather flies in the face of recent vaccine decisions) that considers the risk of Covid (and long Covid) on the cardiovascular system and the need to note and rehabilitation to better manage CV symptoms. Also suggest vaccines are an important tool to prevent such complications

As expected, ACIP have voted through big changes to childhood vaccines schedule with more actions slated today. Firstly, no more combined MMRV - (mumps measles rubella chickenpox) for first dose- instead MMR and chickenpox to be given separately but option for 2nd dose & the combined shot remains 🧪🧵

"An influential CDC vaccine advisory committee that has been reconstituted by HHS RFK will meet Thursday and Friday to discuss changes to the childhood vaccine schedule. These changes, experts say, could make American children less healthy."

As the next meeting of the now-pointless US vax advisory panel is due this week, today felt like a good time to highlight some fact-based, accessible reports that we at @independentsage.bsky.social released this year. independentsage.org/wp-content/u... independentsage.org/wp-content/u...

The sheer extent of the accusations against RFKJr are staggering- pre- approving ACIP decisions without knowing results/seeing evidence, allowing unvetted (and contain falsehoods) presentations at ACIP masquerading as fact, disparaging CDC scientists… 🧪🧵

BREAKING: Royal Society to reconsider expelling Elon Musk Violent rhetoric in address to anti-immigration rally pushes science academy to reassess billionaire’s fellowship (Free to read) www.researchprofessionalnews.com/rr-news-uk-c...

Actuarial innit. If they don’t cover your disease shot, they’re more likely to have to cover your disease. #vaccineswork

A couple thoughts as a reporter who's been covering RFK Jr and watched today's hearing with fired CDC director Susan Monarez 1) the biggest things I heard today were about the CDC's childhood vaccine schedule. Monarez testified that RFK Jr told her he talks to Trump "every day" about changing it.

VAERS (vaccine adverse event reporting system) is an open tool for capturing any adverse event that occurs at some point after a vaccine is administered as part of longer monitoring🧪🧵

A quick summary of developments in US re infections and vaccines. Cuts of CDC staff threaten infectious disease monitoring and research 🧪🧵

A quick summary of developments in US re infections and vaccines. Cuts of CDC staff threaten infectious disease monitoring and research 🧪🧵

🚨 MILLIONS at higher risk will lose NHS Covid vaccines this autumn. Lives will be at risk. The NHS will face more pressure. Covid is as serious as 'flu and also requires updated seasonal vaccines. We can stop this! Sign + share our petition (on next post) 1/ #KeepCovidBoosters

It’s deeply concerning that such huge harm can be done to public health by opportunistic contrarians with no understanding of - how mRNA vaccines work, what T cell exhaustion is, or cancer epidemiology trends - but can spin them all into a word salad to hoodwink the gullible…

This may explain why there’s an aggressive response to people who merely post Kirk’s own words. It threatens the existence of the alternate Kirk - the motivational speaker that had been marketed to young kids and white Christian groups through selective quotation & clips.

Also, over next few weeks work is incredibly busy, so I simply can't do substacks for a while. What spare time I have will be on keeping the TrumpTracker (www.trumpactiontracker.info) up to date. So, see you in a few weeks!

Great to discuss the flagrant disinformation peddled at the Reform conference by Malhotra with @garethiacobucci.bsky.social As @LawrenceYoung11 et al agree, the 💩 re mRNA vax and "turbo cancer" (anyone taking that name seriously?!🤦‍♂️) is pure, insidious fiction designed to ⏫️ hesitancy.

Some personal news: I've been fired from the Washington Post in the aftermath of the Charlie Kirk shooting. Thread incoming. substack.com/@karenattiah...

Interesting to see that Farage has a history with Malhotra dating several years and Malhotra also spoke at a fringe event as well as the main event at the Reform conference so Farage has more questions to answer about platforming a known anti-vaxer

Good to see Trump challenge Ladapo’s move to make vaccines non mandatory for school in Florida and praise some vaccines so will he deal with RFK Jr gradual erosion of vaccine access for all?

Bernie Sanders calls for RFK Jr to step down due to his anti-science beliefs including that hiv doesn’t cause AIDs and that diet can stave off infection harms

Expect more silence from the Royal Society in the face of their most notorious fellow advocating for the overthrow of the democratically elected government of a country he is neither a citizen nor a resident of (yet he is a fellow of their most prestigious learned society).

Esp given assassination of Kirk in US i find Musk's intervention here, calling for dissolution of parliament and a new govt, really scary . Also UK govt bodies should get the fuck off X.

This is McCarthy era behaviour and shame on the university for losing 160 staff n students this way- the accused do not even know what the complaints were about and are not allowed to see the accusations which seems quite frankly out of the 1984 playbook

Trumps rhetoric here is chilling. I fear for the repercussions following his statements on Fox

Its been three years since a complaint was lodged to GNC about Malhotra’s anti- vaccine stance which has seen him continue to grow his sphere of influence reaching into US and now potentially Reform, UK policies

A flawed study pre-print that claimed to show link between mrna vaccines and cancer has been withdrawn thanks to @elisabethbik.bsky.social

Damning report concludes that USA is complicit in ethnic cleansing of Gaza by Israeli forces via a coordinated campaign enabling destruction of homes so that they cannot be lived in & depriving Palestinians of essentials to live

Malhotra, has been a prominent anti-vaccine voice for several years yet GMC did not take concerns about his actions seriously

Really useful update from Bob Hawkins on Long Covid in England from the annual GP survey bhawkins3.substack.com/p/long-covid...

see academic.oup.com/cid/article/...

This sounds great

That was a surprise! Wordle 1,544 2/6 ⬜⬜⬜⬜⬜ 🟩🟩🟩🟩🟩

Good news for those that can get the covid vaccine as the new vaccine has fourfold increase in neutralising antibodies as shown by phase three trials

An estimated 14 million kids don't get any vaccines. They face serious threats from measles, diarrhea, pneumonia and more.