Nature Reviews Molecular Cell Biology (@natrevmcb.nature.com)

Regulation of inflammatory processes by caspases Nature Reviews Molecular Cell Biology, Published online: 02 July 2025; doi:10.1038/s41580-025-00869-6Mammalian caspases are a group of cysteine proteases historically categorized into an ‘inflammatory’ subgroup and an ‘apoptotic’ subgroup, although accumulating evidence indicates that this distinction is not as clearcut as initially thought. Here, we discuss the functions of inflammatory caspases and apoptotic caspases, while proposing that all caspases ultimately regulate inflammation, either directly or by controlling cell death. https://bit.ly/4nA2xQw