Seipin mediates Perilipin-1 recruitment to lipid droplets to preserve human adipocyte identity https://www.biorxiv.org/content/10.1101/2025.11.09.687445v1

Lightweight open-source fine-tuning of SAM2 enables domain-specific microscopy segmentation https://www.biorxiv.org/content/10.1101/2025.11.08.687405v1

Physical, chemical, and structural properties of human gastric organoid-derived mucus https://www.biorxiv.org/content/10.1101/2025.11.08.687257v1

Stress granules and protein aggregates reveal intracellular resource competition https://www.biorxiv.org/content/10.1101/2025.11.08.687377v1

The inner membrane complex protein, IMC55, is dispensable for intra-erythrocytic development of Plasmodium falciparum https://www.biorxiv.org/content/10.1101/2025.11.07.687246v1

Intercellular mitochondrial transfer and transmitophagy in response to protein import dysfunction https://www.biorxiv.org/content/10.1101/2025.11.10.687620v1

Neat1 alleviates ischemic injury in skeletal muscles https://www.biorxiv.org/content/10.1101/2025.11.08.687205v1

Prognosis prediction using autophagy gene expression in osteosarcoma https://www.biorxiv.org/content/10.1101/2025.11.05.685081v1

Spatial Partitioning of Core Glycolysis Enables Tissue-Specific Metabolic Programs In Vivo https://www.biorxiv.org/content/10.1101/2025.11.09.687253v1

Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation. https://www.biorxiv.org/content/10.1101/2025.11.07.687309v1

The CENP-A chaperone complex spatially organizes centromeres https://www.biorxiv.org/content/10.1101/2025.11.07.687291v1

Depletion of microenvironmental syndecan-2 impairs hematopoietic stem cell self-renewal and cytokine responses https://www.biorxiv.org/content/10.1101/2025.11.07.687077v1

Viscoelasticity driven deformation dynamics of the substrate affect mechanically induced Ca2+ signals https://www.biorxiv.org/content/10.1101/2025.11.07.687272v1

Reconstitution of multistep recruitment of ULK1 to membranes in autophagy https://www.biorxiv.org/content/10.1101/2025.11.07.687251v1

Antiphospholipid syndrome (APS) is a platelet factor 4 (PF4)-centric immunothrombotic disorder https://www.biorxiv.org/content/10.1101/2025.11.07.687095v1

Drosophila HS dendrites are resilient to adult-onset deficits in mitochondrial dynamics https://www.biorxiv.org/content/10.1101/2025.11.07.687201v1

Gene editing in "cell villages" enables exploring disease-relevant mutations in many genetic backgrounds https://www.biorxiv.org/content/10.1101/2025.11.08.687374v1

Development of long-term oyster tissue cultures reveals cellular plasticity, regenerative potential, and sustained physiological activity https://www.biorxiv.org/content/10.1101/2025.11.07.687009v1

Microprotein miP-PSTPIP2 affects cytoskeleton dynamics to modulate endothelial cell endocytosis, barrier function and migration https://www.biorxiv.org/content/10.1101/2025.11.07.687176v1

Secondary bile acid lithocholic acid ameliorates colitis-like inflammation in a human intestine-on-chip system https://www.biorxiv.org/content/10.1101/2025.11.07.686950v1

Proteomic characterisation of matrix vesicles from primary osteoblasts indicates a mixed population with both exosomal and ectosomal routes of biogenesis. https://www.biorxiv.org/content/10.1101/2025.11.07.687130v1

HeartMap: An Integrated Cell Atlas of 2.4 million cells across 209 Individuals in Health and Disease https://www.biorxiv.org/content/10.1101/2025.11.06.686995v1

3D Mapping of Intact Ovaries Reveals the Aging Dynamics of the Ovarian Reserve https://www.biorxiv.org/content/10.1101/2025.11.07.686728v1

Preservation of vision after chemically induced retinal ganglion-like-cell transplantation. https://www.biorxiv.org/content/10.1101/2025.11.06.686630v1

Electron transport chain disruption leads to failure of glucose derepression via the Snf1/AMPK pathway https://www.biorxiv.org/content/10.1101/2025.11.06.687039v1

Electron Cryo-Tomography Reveals the Caulobacter vibrioidesTight Adherence Pilus Architecture https://www.biorxiv.org/content/10.1101/2025.11.06.686991v1

Dystonia-associated Torsins sustain CLCC1 function to promote membrane fusion of the nuclear envelope for NPC biogenesis https://www.biorxiv.org/content/10.1101/2025.11.07.687155v1

Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes https://www.biorxiv.org/content/10.1101/2025.11.06.686945v1

ORP5 controls the partitioning of phosphatidic acid between triacylglycerol and cardiolipin synthesis at mitochondria-ER-lipid droplet contact sites https://www.biorxiv.org/content/10.1101/2025.11.06.685814v1

Transcriptomic and functional comparison of cells isolated from healthy and degenerated ovine intervertebral discs https://www.biorxiv.org/content/10.1101/2025.11.06.686904v1

Extra-ciliary role for polycystins in regulation of Ezrin and renal tubular morphology https://www.biorxiv.org/content/10.1101/2025.11.05.684799v1

An Asgard archaeon with internal membrane compartments https://www.biorxiv.org/content/10.1101/2025.11.06.686947v1

The APOL1 variant p.N264K blocks ion flow by occluding a pore at the cell surface https://www.biorxiv.org/content/10.1101/2025.11.05.686714v1

Derivation, Characterizations, and Applications of Rabbit Haploid Embryonic Stem Cells https://www.biorxiv.org/content/10.1101/2025.11.05.686447v1

Sparse delivery of Synaptobrevin-2 to neurons using extracellular vesicles https://www.biorxiv.org/content/10.1101/2025.11.04.686638v1

The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition https://www.biorxiv.org/content/10.1101/2025.11.04.686150v1

BCHS acts as a stress transducer connecting autophagic quality control with DNA damage repair https://www.biorxiv.org/content/10.1101/2025.11.04.685471v1

Cryptococcus neoformans employs both PP1 and PP2A phosphatases to silence the spindle checkpoint https://www.biorxiv.org/content/10.1101/2025.11.04.686612v1

Aberrant 5-Methylcytosine tRNA Modification Disrupts Proteostasis and Exacerbates Age-Related Osteoporosis https://www.biorxiv.org/content/10.1101/2025.11.04.686482v1

Fission yeast cells use distinct cell size control mechanisms for size adaptation to osmotic, oxidative, or low glucose conditions https://www.biorxiv.org/content/10.1101/2025.11.04.686600v1

GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombination https://www.biorxiv.org/content/10.1101/2025.11.04.686352v1

A role for the Stentor syntaxin protein in post-wound cell survival https://www.biorxiv.org/content/10.1101/2025.11.04.686591v1

Superoxide dismutase impacts extracellular vesicle biogenesis and uptake https://www.biorxiv.org/content/10.1101/2025.11.04.686557v1

Genetic interaction of Specc1l and Thm1 reveals cytoskeletal - ciliary crosstalk https://www.biorxiv.org/content/10.1101/2025.11.03.686369v1

Cisplatin and Copper Induce Distinct Endocytic Pathways of Copper Transporter-1 and Elicits Unique Response on Copper Homeostasis Proteins https://www.biorxiv.org/content/10.1101/2025.11.03.686439v1

A multidisciplinary approach for the study of age-dependent expression patterns in porcine experimental wounds https://www.biorxiv.org/content/10.1101/2025.11.04.686454v1

Sequestration of clock proteins into repressive nuclear condensates orchestrates circadian gene repression https://www.biorxiv.org/content/10.1101/2025.11.03.686412v1

Rapamycin can revert CCM phenotype in brain endothelial cells and ameliorates chronic cavernoma development in combination with lapatinib https://www.biorxiv.org/content/10.1101/2025.11.03.686432v1

Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells https://www.biorxiv.org/content/10.1101/2025.11.03.685424v1

The Function of Efhd1+ Telocytes in the Synovial Lymphatic System and Inflammatory-Erosive Arthritis https://www.biorxiv.org/content/10.1101/2025.11.03.685859v1