My PhD students Aoi Otsuka @masaashimazoe.bsky.social et al. published @csf-jscb.bsky.social 🎉 Single-nucleosome imaging in an oncogene-inducible human carcinogenesis model shows biphasic chromatin dynamics (1–3 d same; 5–7 d ↑; back by week 4). Congrats! 👉 doi.org/10.1247/csf....

Congrats Tegan!🎉

📣Plant Meiosis Meeting is back for its second edition‼️ Save the date: 9–11 September 2026, Poznań, Poland🌱 More details coming soon🤩

Hey #CellBio2025, want to learn how rRNAs tell the cell about the quantity of ribosmal DNA in the genome? Come by poster board 054 this afternoon to learn about the lab's recent work!

Huge congrats Ben!!🎉

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

We had a nice cycling trip on a perfect autumn day to celebrate Takaya’s recent paper!🚲 Congrats again!🎉 www.cell.com/current-biol...

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on. (Please repost to reach a broad audience.)

🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

Very exciting news: My first first-author paper is now out (open access!) in Chromosoma! link.springer.com/article/10.1...

Don’t look away. What some people call ‘suicidal empathy’ other (medical professionals) might call ‘psychopathy’

Wow. Neat. Congratulations!!!

Among the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social www.science.org/doi/10.1126/...

Dr. Steven Henikoff receives the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research. www.brandeis.edu/rosenstiel/r... (Personal note: I continue to be inspired and astonished by my postdoctoral mentor & current colleague)

🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/

"There’s a cancer running through Washington, D.C., and I’m running to cure it." #NC11 www.maddoxforcongress.com/2025/10/24/l...

When all your PCRs fail, except for the negative control 😱

Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it? Turns out we can harness the power of bacteria to power the world’s smallest machines. 1/7 ⚛️🧪

What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...

Happy Sunday ovo-lovers! A new issue of #cebooc is here! biomed.news/bims-cebooc/... This week 2 stunning highlights: pubmed.ncbi.nlm.nih.gov/41129643/ and pubmed.ncbi.nlm.nih.gov/41131150/ Thanks @biomednews.bsky.social for preselecting!

非天然アミノ酸の効率的導入 タンパク質設計における非天然アミノ酸の導入のボトルネックに、細胞内取り込み効率の低さがある。今回細菌のトランスポーターを利用/改変して同時に最大2つの非天然アミノ酸を高効率に導入する手法を確立。基礎から応用まで発展に期待 www.nature.com/articles/s41...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Scm3 interacts with the N-terminal tail of Cse4 to regulate kinetochore assembly in budding yeast https://www.biorxiv.org/content/10.1101/2025.10.20.683541v1

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️. Check out the new paper: www.cell.com/molecular-ce...

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n jobs.utoronto.ca/job/Toronto-... jobs.utoronto.ca/job/Toronto-...

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share. www.jobs.ac.uk/job/DOW912/s...

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

PhD or Master's position available for Fall 2026! Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont... Please share!

Congrats Mia and Mike🎉 Great paper for journal club!

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone

🚨 New from our lab in #ScienceAdvances! RAD21L cohesin acts as both a 3D genome architect and a transcriptional gatekeeper in the male germline. Its loss disrupts both structure and function—highlighting the tight link between genome folding and gene regulation www.science.org/doi/10.1126/...

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

"If we lose hope, we're doomed." We must continue Dr. Jane Goodall's mission and all fight for the future of the planet.

JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

Dr. Jane Goodall, 1934-2025 An exceptional scientist, and a singular woman in science #WomeninScience 🐒 www.nytimes.com/2025/10/01/o...

Huge congrats, Chloe!!🎉

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction! Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1 doi.org/10.1101/2025...

Super excited that this story by @borissieber.bsky.social is now on BioRxiv! For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it ! See the thread 👇 and enjoy the paper! doi.org/10.1101/2025...

Congrats Jen, Adam, and the team!!🎉🥂Love this work.

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3] 📺 youtu.be/JmlY5omxQVc 📄 www.nature.com/articles/s41...

Know rising stars in biological, medicinal, or pharmaceutical chemistry? Nominate them for a feature. Link to a blog post and the nomination form below! axial.acs.org/biology-and-...

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Tenure-track Assistant Professor in Computational Ecology and/or Evolution @columbiauniversity.bsky.social. Deadline to apply September 30. Reach out if you have questions. apply.interfolio.com/172496