Restoring Shugoshin 1 reduces chromosome errors in human eggs https://www.biorxiv.org/content/10.64898/2026.01.08.698387v1

Next generation open access?? www.jisc.ac.uk/news/all/lan...

What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....

The discovery of the first kinetochore proteins (CENP-A, CENP-B, CENP-C) was reported by Bill Earnshaw and Naomi Rothfield in 1985 in Chromosoma. Forty years later, Chromosoma/Chromosome Research has published a special issue (most articles are open access) link.springer.com/collections/...

Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍 W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social journals.biologists.com/jcs/article/...

Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles! www.biorxiv.org/content/10.6...

Mitosis is beautiful

Yes, this experiment says a lot...

Self-citations are not elegant, yet I feel that much of what we need to know about the robustness of "LLPS scaffolds" is summarized in this figure doi.org/10.1016/j.mo...

#Diplonemids are among the most diverse & abundant #protists in the deep #ocean. This study localises >5,000 proteins of #Paradiplonema papillatum, revealing #organelle compartmentalisation, including a membrane coated with carbohydrate-degrading enzymes @plosbiology.org 🧪 plos.io/3XvmpIO

whether you agree with Andrea or not, what he is doing is very important for a healthy scientific culture. Thank you @andrea-musacchio.bsky.social for setting a great example for all of us: Speak your mind even if it is against the mainstream flow.

There is always pseudoscience out there some of which are excellent at gaining momentum (and people, money, power) because they sound attractive. But pseudoscience is pseudoscience. Time will tell. As a scientist, one should judge what's right/wrong by themselves

So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth! #protistsonsky 🧵

A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration. www.nature.com/articles/s41...

I however wonder why a new supergroup was erected (Disparia) when the existing supergroup Promethea precisely describes this grouping? Promethea was published here: www.cell.com/iscience/ful...

Why IDPs Are Poor Candidates for Homotypic LLPS 🧵👇A thread

Why LLPS Scaffolds Cannot Exist – A Thermodynamic Thread If you consider arguments logical, please share. Else please expose logical faults 🧵👇

Trypanosoma

Deadline 18th Nov! Please write to express your support for continued funding for Jalview!

I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow! discourse.jalview.org/t/write-a-le...

Radiolarian - a huge one!

It’s a beautiful afternoon. Dive 3 (864). We are taking Subastian into a deep underwater canyon. Live feed will begin soon: www.youtube.com/@SchmidtOcea...

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

And!! www.biorxiv.org/content/10.1...

Simply looking at the 60 pages of images is just so much fun. Data S1 console.s3.embl.de/browser/cult...

Only the second radiolarian I’ve seen in my life, and this one is a chonks! #marineplankton #protistsonsky 🦑

I was happy with the cell counter which worked for more than 10 years. When I bought a new one recently, the company sent a newer version, which turned out to be an absolute nightmare

Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm Alexis Barr, Francis Barr and John Tyson remember Béla Novák. journals.biologists.com/jcs/article/...

We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.

HHMI adopts Plan U journals.plos.org/plosbiology/...

Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes

Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026! Keep an eye on the BSP website for registration and abstract submission! Logo by @shannaraeilean.bsky.social! 🦟

A big welcome to everyone who has joined us for the @bspparasitology.bsky.social trypanosomiasis and leishmaniasis meeting this week in the beautiful city of Ceske Budějovice!

I guess I have been quite open about my ongoing diplonema project, showing PCR results, live cell imaging, IF attempts, some interesting localization. For example, my tweet about "one of two flagella" protein led to conversations with various people I had not talked to. It's been so much fun

Core funding, Orbitrap Astral, Aquilos 2, super low facility charges, etc etc

Building a synthetic cell together - nice common perspective written by many leading scientists who gathered in Shenzhen China for the inaugural ‘SynCell Global Summit’. Check it out in Nature Comm: www.nature.com/articles/s41...

Hotel ISG, EMBL

In Tokyo last month. In Heidelberg this week. Let's see what kind of images we can get

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...

The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years! Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out. link.springer.com/article/10.1...

📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️ elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes? www.biorxiv.org/content/10.1...

Subcellular proteomics of Paradiplonema papillatum reveals digestive capacity of the cell membrane and the plasticity of peroxisomes across euglenozoans https://www.biorxiv.org/content/10.1101/2025.07.16.665091v1

The problem is that the more I understand, the less it makes sense. Something is not right