Archaeaophiles! Last chance to sign up as a virtual attendee for MBoA2026. It’s cheap and you will have access to all the talks include our archaea@50 celebration with a special guest: meetings.embo.org/event/26-arc...

Excited to be part of this fantastic project!

Archaea are the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria for a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.

now published!!! @johninnescentre.bsky.social @leahmcphillips.bsky.social academic.oup.com/nar/article/...

New preprint! Cell division has to happen at the right place but how Archaea pick that place is unknown. We now identified a three-protein system, Dip, that positions the divisome at midcell in H. volcanii and is broadly conserved across Archaea. A thread 🧵 www.biorxiv.org/content/10.6...

The Bisson Lab at IU (bissonlab.com) is hiring makers/builders/engineers across all career stages to join our team in one of the most exciting and crazy projects I've set to work on. Candidates can email us: [email protected] More info in the thread [1/3]

how does loop extrusion and chromatid cohesion interact in interphase? Find out in our latest collaboration with Gerlich lab | | | vvv

New preprint alert! Together with Tetsuya Yamamoto at Hokkaido University, we propose a “polymer micelle” model of transcriptional bursting. www.biorxiv.org/content/10.6...

Our new preprint! 🧬✨ www.biorxiv.org/cgi/content/... @ynagata.bsky.social et al. combined single-nucleosome imaging with Fucci probes to follow local chromatin behavior during interphase. Local nucleosome motion stays nearly constant from G1 to G2, except in early G1. Thanks to all coauthors!

🚨Pls repost!🚨 I'm looking for a postdoc who will lead the research investigating the mechanisms of epigenetic reprogramming using mouse embryos. Background in chromatin biology and genomics is desirable. The application deadline is 28 May. Please apply here!! www.dundee.ac.uk/work-for-us/...

Paper published! PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes -PDS5 facilitate NIPBL dissociation from cohesin, stopping loop extrusion -Extrusion governs chrm compartmentalization by competing w/polymer relaxation authors.elsevier.com/sd/article/S...

【NEWS】EMBO–MBSJ Laboratory Leadership Forum 2026 in Tokyo Institute of Science Tokyo Yushima Campus, M&D Tower Saturday, June 27, 2026 To foster diverse perspectives in the discussions, we also encourage applications from women researchers. sites.google.com/view/embo-mb...

Our latest paper is online. www.nature.com/articles/s41... We expanded the speed-optimized DNA-PAINT sequences from 6 to 12 — enabling faster, higher-resolution multiplexed super-resolution imaging of up to 10 cellular targets. Here's the story. 1/n

Now published in @cytoskeljournal.bsky.social !🎉 Diurnal Regulation of Flagellar Length and Swimming Speed in the Red-Tide Raphidophyte Chattonella marina 🔗 doi.org/10.1002/cm.7... © 2026 Wiley #protistsonsky

🚨Hear, hear, fellow microbial cell biologists!🚨 🦠 Bacterial and Archaeal Cell Biology will be represented again at this year’s CELL BIO (ASCB-EMBO) meeting! The deadline to be considered for a talk in our Minisymposium is June 9. Help us spread the word! www.ascb.org/cellbio2026/

Hearts have topological defects. By treating the mouse myocardium as a 3D nematic, we found disclination lines threading through it. In situs inversus hearts, twist must match structural chirality for contraction to work, as found by quantifying the nematic chirality. biorxiv.org/content/10.6...

Finally published. Many thanks to a wonderful collaborative team and scientific platforms!!! And thanks to editors and reviewers for enthusiasm and a great review. www.nature.com/articles/s41...

Very pleased to say that the paper version of our study examining the role of de novo DNMTs in cancer-associated hypomethylation is now out in @plos.org Genetics 🎉: doi.org/10.1371/jour... You can read more on the previous thread but here is a summary of the main updates! #epigenetics 🧵 1/9

Excited to share our structural insights into how microtubules differentially guide phosphorylation of kinetochore-microtubule regulators, Ndc80 and MCAK, for chromosome segregation. Heroic efforts by Yiming Niu with a fun collaboration with Jennifer DeLuca lab! www.science.org/doi/10.1126/...

My first, first author paper is now on #ScienceAdvances ! Linker histone H1 is a liquid-like "glue" condensing chromatin, which revises textbooks! 📖✨ science.org/doi/10.1126/sc… Huge thanks to @kazu-maeshima.bsky.social , for supervision. Amazing collab with @rcollepardo.bsky.social ’s group! 1/

🧬 Last call to join us in Cambridge for #EMBOMBoA26 (July 6th-10th)! We are just one week away from the registration and abstract submission deadline for the EMBO Workshop on the Molecular Biology of Archaea!

【拡散希望】私も運営に携わらせてもらっているEMBO–MBSJ Laboratory Leadership Forumが6月27日に東京で開催されます！ラボ運営に必要なスキルについて学べる貴重な機会だと思いますので、みなさん是非ご参加ください！

【NEWS】EMBO–MBSJ Laboratory Leadership Forum 2026 in Tokyo Institute of Science Tokyo Yushima Campus, M&D Tower (formerly Tokyo Medical and Dental University) Saturday, June 27, 2026 sites.google.com/view/embo-mb...

I wrote an essay. It’s about gain-of-function mutations. And penguins. Also ion channels, chihuahuas, the film Alien, recycled cardboard, and the Apollonian mind. Oh, and muffins. Thanks to the editors of #GENETICS @genetics-gsa.bsky.social for letting me take some stylistic liberties. 1/2

🚨Another open position in the lab! A long-term Staff Scientist position for people who love working on the bench!!👩🏻‍🔬👨‍🔬The Staff Scientist will function semi-independently in the lab to manage multiple projects 🧬🐭🔬#meiosis4eva

Happy to have been part of the study! “Transient residence of the repulsive client Shutdown in Yb bodies plays a critical role in Piwi-piRISC biogenesis and maintaining fertility” www.cell.com/molecular-ce...

New preprint! We identified many components that localize to the structure involved in "eating" in a marine organism. #ProtistOnSky #diplonemid www.biorxiv.org/content/10.6...

New review in @cp-trendsgenetics.bsky.social on the fascinating world of chromatin organization in Asgard archaea. Very nice joint effort with @jvhooff.bsky.social www.sciencedirect.com/science/arti...

We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️

I am excited to have been awarded a Wellcome Trust CDA fellowship. This award allows us to dissect the mechanistic basis for trophectoderm lineage commitment across scales, from atoms to embryos. I will start the recruitment for several positions. Stay tuned! www.dundee.ac.uk/news/wellcom...

Happy to share our work on conventional and time-resolved cryo-EM studies of NTSR1, now published in Nature! nature.com/articles/s41... Wonderful collab. w/ Sumino, Mitsutake, Kobilka, & Inoue labs. Congrats to Kazuhiro, Kouki, Toshiki, Shun & everyone involved!

www.biorxiv.org/content/10.6... Amazing work by Kris and gang! For the first time we have been able to image division ring components live in Sulfolobus. And guess what - CdvA is asymmetrically inherited.

The collaboration with the Taka Nojima lab (Kyushu University) and the Michael Tellier lab (University of Leicester) was published in EMBO Reports! We contributed to this work by analysing the effect of transcription termination defects on DNA replication. link.springer.com/article/10.1...

Congrats Duilio on discovering the 1st Toxin-Antidote system in vertebrates! 🎉He single-handedly established the embryo project in my lab!👍

We’re recruiting a postdoc to start at the end of this year or early next year! We use cryo-EM to uncover the structural basis of key chromatin events using native complexes isolated from human cells or assembled in Xenopus (frog) egg extracts!

Diving into evolutionary biology! What is the origin of the most abundant class of insect transcription factors, ZAD-ZnFs? We suggest that they evolved from ancestral insulator-binding proteins that control 3D genome topology. www.science.org/doi/10.1126/...

📢 Save the date! #Biophychrom2027 will take place at Paris-Saclay in July 2027. More details coming soon!

At the first health checkup of our second baby after his discharge. Having a lot of fun parenting 24 h😪

Now online: Pingzhuang Ge's studies on the impact of pH on local chromatin structure and transcriptional activity of the H-NS-regulated hdeAB operon www.biorxiv.org/content/10.6...

Another announcement! 📣 Our work on hybrid incompatibility in cohesin protection in 🐭oocytes is published!! Congrats Warif El Yakoubi and Eddie Pan!!🎉 We found hybrids with cohesion errors in two distinct genus. www.science.org/doi/10.1126/...

Preprint alert: Jiangyuan Liu developed a new workflow for chromatin loop calling across Hi-C datasets, e.g., during differentiation. Most loops are shared between datasets/cell states. Important work for all interested in chromatin loops and how to identify them! www.biorxiv.org/content/10.6...

I am very pleased to share that our database of prokaryotic and viral histones, ProHistoneDB, is now available online at prohistonedb.org. Please also see the accompanying article in J Mol Biol: doi.org/10.1016/j.jm...

@archaellum.bsky.social lab reveals how #cdiAMP and 4 RCK proteins shape osmotic stress responses in H. volcanii 🧬🦠. In highly halophilic #archaea, c-di-AMP coordinates ion balance and cell volume—mirroring bacterial strategies for environmental stress adaptation. 👉 buff.ly/ApWkCtg

Ordering of cell cycle events by regulated proteolysis is not just for eukaryotes: @buzzbaum.bsky.social et al define mechanisms underlying switch-like degradation of archaeal ESCRT-III CvdB in Sulfolobus Thanks to @reviewcommons.org for another #RefereedPreprint link.springer.com/article/10.1...

I’m honored to give a seminar at the TUM School of Life Sciences in January. I’ll be presenting our work on multi-omics analysis. I look forward to the discussion! www.ls.tum.de/en/ls/public...

Happy to share a protocol for analysis of TF-nucleosome interactions and cryo-EM structure determination in STAR Protocols. I had a great opportunity to describe this protocol with @aliciakmichael.bsky.social. Thank you very much, all! www.sciencedirect.com/science/arti...

My PhD students Aoi Otsuka @masaashimazoe.bsky.social et al. published @csf-jscb.bsky.social 🎉 Single-nucleosome imaging in an oncogene-inducible human carcinogenesis model shows biphasic chromatin dynamics (1–3 d same; 5–7 d ↑; back by week 4). Congrats! 👉 doi.org/10.1247/csf....

Exciting new paper out! @allanaschooley.bsky.social and Sergey Venev led this project that let to the discovery of two chromosome folding programs: one inherited via mitotic chromosomes and one mitotic inherited through the cytoplasm! www.nature.com/articles/s41...

Proud of contributing to this work on archaeal chromosome segregation! Congrats, Rachel and Steve! www.nature.com/articles/s41...